Toshihito Suzuki

Summary

Affiliation: University of Tsukuba
Country: Japan

Publications

  1. pmc The (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals
    K Imai
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba City, Ibaraki, Japan
    BMC Psychiatry 1:1. 2001
  2. ncbi request reprint Effects of cocaine administration on receptor binding and subunits mRNA of GABA(A)-benzodiazepine receptor complexes
    T Suzuki
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tennodai, Tsukuba, Japan
    Synapse 38:198-215. 2000
  3. ncbi request reprint Drug-induced Pisa syndrome (pleurothotonus): epidemiology and management
    Toshihito Suzuki
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    CNS Drugs 16:165-74. 2002
  4. ncbi request reprint Time course for memory dysfunction in early-life and late-life major depression: a longitudinal study from the Juntendo University Mood Disorder Project
    Hitoshi Maeshima
    Juntendo University Mood Disorder Project JUMP, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan
    J Affect Disord 151:66-70. 2013
  5. doi request reprint Prenatal phencyclidine exposure alters hippocampal cell proliferation in offspring rats
    Atsushi Tanimura
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan
    Synapse 63:729-36. 2009
  6. doi request reprint Heterogeneity of elderly depression: increased risk of Alzheimer's disease and Aβ protein metabolism
    Yuki Namekawa
    Juntendo University Mood Disorder Project JUMP, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 43:203-8. 2013
  7. doi request reprint Plasma alanine levels increase in patients with schizophrenia as their clinical symptoms improve-Results from the Juntendo University Schizophrenia Projects (JUSP)
    Tokiko Hatano
    Juntendo University Schizophrenia Projects JUSP, Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    Psychiatry Res 177:27-31. 2010
  8. doi request reprint Effects of single and repeated electroconvulsive stimulation on hippocampal cell proliferation and spontaneous behaviors in the rat
    Kyoko Nakamura
    Department of Psychiatry, Juntendo University Faculty of Medicine, Tokyo, Japan
    Brain Res 1491:88-97. 2013
  9. ncbi request reprint Effects of repeated phencyclidine administration on adult hippocampal neurogenesis in the rat
    Juan Liu
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan
    Synapse 60:56-68. 2006
  10. doi request reprint Residual memory dysfunction in recurrent major depressive disorder--a longitudinal study from Juntendo University Mood Disorder Project
    Hitoshi Maeshima
    Juntendo University Mood Disorder Project, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan
    J Affect Disord 143:84-8. 2012

Collaborators

Detail Information

Publications31

  1. pmc The (CTG)n polymorphism in the NOTCH4 gene is not associated with schizophrenia in Japanese individuals
    K Imai
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba City, Ibaraki, Japan
    BMC Psychiatry 1:1. 2001
    ....
  2. ncbi request reprint Effects of cocaine administration on receptor binding and subunits mRNA of GABA(A)-benzodiazepine receptor complexes
    T Suzuki
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tennodai, Tsukuba, Japan
    Synapse 38:198-215. 2000
    ....
  3. ncbi request reprint Drug-induced Pisa syndrome (pleurothotonus): epidemiology and management
    Toshihito Suzuki
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    CNS Drugs 16:165-74. 2002
    ..Idiopathic Pisa syndrome is characterised by an adult-onset, segmental truncal dystonia in patients with no previous exposure to antipsychotics. It occurs rarely but shows a complete resolution with high doses of anticholinergic drugs...
  4. ncbi request reprint Time course for memory dysfunction in early-life and late-life major depression: a longitudinal study from the Juntendo University Mood Disorder Project
    Hitoshi Maeshima
    Juntendo University Mood Disorder Project JUMP, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan
    J Affect Disord 151:66-70. 2013
    ..The present study compared patients during early-life (age<60) and late-life (age ≥ 60) depression while in their remitted stage with healthy controls to elucidate the impact of a long-term course on memory...
  5. doi request reprint Prenatal phencyclidine exposure alters hippocampal cell proliferation in offspring rats
    Atsushi Tanimura
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan
    Synapse 63:729-36. 2009
    ..Changes to cell proliferation in the hippocampus may affect behavioral abnormalities during infancy in offspring...
  6. doi request reprint Heterogeneity of elderly depression: increased risk of Alzheimer's disease and Aβ protein metabolism
    Yuki Namekawa
    Juntendo University Mood Disorder Project JUMP, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 43:203-8. 2013
    ..201, p=0.032). These results suggest that an earlier onset of MDD may have a more serious abnormality in Aβ metabolism, possibly explaining a biological mechanism underlying the link between depression and AD...
  7. doi request reprint Plasma alanine levels increase in patients with schizophrenia as their clinical symptoms improve-Results from the Juntendo University Schizophrenia Projects (JUSP)
    Tokiko Hatano
    Juntendo University Schizophrenia Projects JUSP, Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    Psychiatry Res 177:27-31. 2010
    ..Drug-naïve patients did not show a significant difference in plasma alanine levels when compared with healthy controls. The measurement of plasma alanine levels may be a therapeutic marker for schizophrenia...
  8. doi request reprint Effects of single and repeated electroconvulsive stimulation on hippocampal cell proliferation and spontaneous behaviors in the rat
    Kyoko Nakamura
    Department of Psychiatry, Juntendo University Faculty of Medicine, Tokyo, Japan
    Brain Res 1491:88-97. 2013
    ..These results suggest that repeated ECSs affect progenitors that have a limited ability for cell proliferation, like amplifying progenitors, to increase newly generated neurons without negative behavioral change...
  9. ncbi request reprint Effects of repeated phencyclidine administration on adult hippocampal neurogenesis in the rat
    Juan Liu
    Department of Psychiatry, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan
    Synapse 60:56-68. 2006
    ..Further studies are required to elucidate the biological significance of hippocampal neurogenesis in the mechanisms underlying the development of cognitive dysfunctions and the psychosis of schizophrenia...
  10. doi request reprint Residual memory dysfunction in recurrent major depressive disorder--a longitudinal study from Juntendo University Mood Disorder Project
    Hitoshi Maeshima
    Juntendo University Mood Disorder Project, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan
    J Affect Disord 143:84-8. 2012
    ..This study compared patients with recurrent and single-episode depression in the remitted stage, and healthy controls to elucidate the impact of the number of depressive episodes on memory...
  11. doi request reprint Association analysis between functional polymorphism of the rs4606 SNP in the RGS2 gene and antipsychotic-induced Parkinsonism in Japanese patients with schizophrenia: results from the Juntendo University Schizophrenia Projects (JUSP)
    Masayuki Higa
    Juntendo University Schizophrenia Projects JUSP, Department of Psychiatry, Juntendo University, School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Neurosci Lett 469:55-9. 2010
    ..Taken together, these results, although preliminary, suggest that rs4606 does not affect AIEPSs in Japanese subjects...
  12. doi request reprint Effects of repeated electroconvulsive seizure on cell proliferation in the rat hippocampus
    Masanobu Ito
    Department of Psychiatry, Juntendo University Faculty of Medicine, Tokyo, Japan
    Synapse 64:814-21. 2010
    ..These findings indicate that the optimal number of treatments and duration of stimulation requires investigation. Further studies are needed to elucidate the intracellular mechanisms underlying both effective and excessive ECT...
  13. doi request reprint Association study between Disrupted-in-Schizophrenia-1 (DISC1) and Japanese patients with treatment-resistant schizophrenia (TRS)
    Yuri Hotta
    Juntendo University Schizophrenia Projects, Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 35:636-9. 2011
    ..Taken together, results showed that DISC1 had no apparent degree of association with Japanese patients with schizophrenia as a candidate susceptibility gene for disease per se or TRS...
  14. ncbi request reprint Duration of last depressive episode may influence serum BDNF levels in remitted patients with major depression
    Naoko Takebayashi
    Department of Psychiatry, Juntendo University, School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, Japan
    Depress Anxiety 29:775-9. 2012
    ..The purpose of the present study was to determine which factors influence the alteration of serum BDNF levels in depression in the remitted state...
  15. doi request reprint Changes in plasma glycine, L-serine, and D-serine levels in patients with schizophrenia as their clinical symptoms improve: results from the Juntendo University Schizophrenia Projects (JUSP)
    Tohru Ohnuma
    Juntendo University Schizophrenia Projects JUSP, Department of Psychiatry, Juntendo University, School of Medicine, 2 1 1 Hongo Bunkyo ku, Tokyo 113 8421, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:1905-12. 2008
    ..The plasma levels of these amino acids during the clinical course of schizophrenia were also compared...
  16. ncbi request reprint Decreased cell proliferation in the dentate gyrus of rats after repeated administration of cocaine
    Mika Yamaguchi
    Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Synapse 58:63-71. 2005
    ..These data imply that the regulation of hippocampal cell proliferation by cocaine may be involved in the development of certain symptoms of addiction, such as cognitive impairment and acquisition of behavioral sensitization...
  17. doi request reprint Executive dysfunction in remitted late-life depression: Juntendo University Mood Disorder Projects (JUMP)
    Kanako Baba
    Department of Psychiatry, School of Medicine, Juntendo University, Tokyo, Japan
    J Neuropsychiatry Clin Neurosci 22:70-4. 2010
    ....
  18. ncbi request reprint Repeated cocaine administration differentially affects NMDA receptor subunit (NR1, NR2A-C) mRNAs in rat brain
    Mika Yamaguchi
    Department of Psychiatry, Juntendo Koshigaya Hospital, Juntendo University, School of Medicine, Koshigaya, Saitama, Japan
    Synapse 46:157-69. 2002
    ..Further studies on the changes in non-NMDA receptors are required to elucidate the biological significance of glutamate receptors for the mechanisms underlying the development of behavioral sensitization...
  19. ncbi request reprint Effects of single and repeated phencyclidine administration on [3H]flunitrazepam binding in rat brain
    Shuzo Abe
    Department of Psychiatry, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 29:133-40. 2005
    ....
  20. doi request reprint Serum amyloid beta protein in young and elderly depression: a pilot study
    Yohei Kita
    Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan
    Psychogeriatrics 9:180-5. 2009
    ..Although several studies have examined Abeta levels in the peripheral blood of elderly individuals with depression, results have been inconsistent. Furthermore, no results have been described for younger depression...
  21. ncbi request reprint Hypothesis: minimal changes in neural transmission in schizophrenia: decreased glutamatergic and GABAergic functions in the prefrontal cortex
    Tohru Ohnuma
    Department of Psychiatry, Juntendo University, School of Medicine, 2 1 1 Hongo, Tokyo 113 8421, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 29:889-94. 2005
    ..But these changes are small and failed to be statistically significant. The "receptors/transporters ratio" for each case magnified these changes, such that they became statistically significant...
  22. doi request reprint Correlations between brain-derived neurotrophic factor and clinical symptoms in medicated patients with major depression
    Emi Satomura
    Department of Psychiatry, Juntendo University, School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo, Japan
    J Affect Disord 135:332-5. 2011
    ..However, few investigations have examined the relationship between serum BDNF and detailed clinical symptoms. The aim of present study was to clarify the magnitudes of the relationships between various depressive symptom and serum BDNF...
  23. doi request reprint Executive dysfunction in medicated, remitted state of major depression
    Yoshiyuki Nakano
    Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    J Affect Disord 111:46-51. 2008
    ....
  24. ncbi request reprint Comparative study of cognitive impairment between medicated and medication-free patients with remitted major depression: Class-specific influence by tricyclic antidepressants and newer antidepressants
    Akiko Nagane
    Juntendo University Mood Disorder Project JUMP, Department of Psychiatry, Juntendo Koshigaya Hospital, Saitama, Japan Shumeikai Minami saitama Hospital, Saitama, Japan Shumeikai Izumi Clinic, Saitama, Japan
    Psychiatry Res 218:101-5. 2014
    ..These results suggest that cognitive impairment remained even in remitted patients with MDD, however, part of this impairment may be influenced by class-specific antidepressant side effects. ..
  25. ncbi request reprint Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia -- Juntendo University Schizophrenia Projects (JUSP)
    Hitoshi Maeshima
    Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:1410-8. 2007
    ..Although GLS and GLS2 are not likely genetic risk factors for schizophrenia, changes in plasma glutamate concentration might be connected with clinical course of schizophrenia...
  26. ncbi request reprint Expression of nNOS and soluble guanylate cyclase in schizophrenic brain
    Hajime Baba
    Department of Psychiatry, Juntendo University, School of Medicine, Tokyo, Japan
    Neuroreport 15:677-80. 2004
    ..Abnormalities of nNOS expression in the brain might contribute to the development of schizophrenia...
  27. ncbi request reprint The effects of mental state on assessment of bipolar temperament
    Hajime Baba
    Department of Psychiatry, Juntendo University School of Medicine, Japan Department of Psychiatry, Juntendo Koshigaya Hospital, Japan
    J Affect Disord 161:1-3. 2014
    ..For the purpose of clarifying the effects of mental state on TEMPS-A scores, it is worthwhile to examine associations of the full version of the TEMPS-A with various depressive scales and, if possible, mania rating scales...
  28. ncbi request reprint Case reports and literature review: the association between reactivation of human herpes virus-6 and peripheral white blood cell count in patients with carbamazepine-induced hypersensitivity syndrome
    Kentaro Matsuda
    Department of Psychiatry, Juntendo Koshigaya Hospital, 560 Fukuroyama, Koshigaya shi, Saitama 343 0032, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:751-4. 2006
    ..When an increase in white blood cells are observed in HS cases at onset, immediate discontinuation of cause drug and intensive care are necessary to avoid the more severe symptoms of HS...
  29. ncbi request reprint Nicotine effects on mismatch negativity in nonsmoking schizophrenic patients
    Rie Inami
    Department of Psychiatry, Juntendo University School of Medicine, Koshigaya, Japan
    Neuropsychobiology 56:64-72. 2007
    ..The goal of the present study is to identify the effect of nicotine on auditory automatic processing, as reflected by mismatch negativity (MMN), in nonsmoking schizophrenic patients...
  30. ncbi request reprint Repeated cocaine administration increases GABA(B(1)) subunit mRNA in rat brain
    Mika Yamaguchi
    Department of Psychiatry, Institute of Clinical Medicine, Institute of Basic Medical Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Ibaraki 305 8575, Japan
    Synapse 43:175-80. 2002
    ..The observed changes in the mRNA level after the repeated cocaine may imply changes of GABA(B(1)) subunit in molecular mechanisms which underlie development of behavioral sensitization...
  31. ncbi request reprint Risperidone failed to improve polydipsia-hyponatremia of the schizophrenic patients
    Nobutoshi Kawai
    Department of Clinical Psychiatry, Mitsukaido Kosei Hospital, Mitsukaido, Japan
    Psychiatry Clin Neurosci 56:107-10. 2002
    ..Although the sample size is relatively small, our preliminary data showed that risperidone might not be effective on polydipsia-hyponatremia of schizophrenic patients...