Tetsuro Shirasaka

Summary

Affiliation: University of Miyazaki
Country: Japan

Publications

  1. doi request reprint High-dose remifentanil increases blood pressure and heart rate mediated by sympatho-activation in conscious rats
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, 5200 Kihara Kiyotake, Miyazaki, Japan
    J Anesth 27:325-32. 2013
  2. ncbi request reprint The effects of centrally administered dexmedetomidine on cardiovascular and sympathetic function in conscious rats
    Tetsuro Shirasaka
    Department of Anesthesiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
    Anesth Analg 105:1722-8, table of contents. 2007
  3. ncbi request reprint Activation of a G protein-coupled inwardly rectifying K+ current and suppression of Ih contribute to dexmedetomidine-induced inhibition of rat hypothalamic paraventricular nucleus neurons
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Japan
    Anesthesiology 107:605-15. 2007
  4. doi request reprint Effects of orexin-A on propofol anesthesia in rats
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, 5200 Kihara Kiyotake, Miyazaki 889 1692, Japan
    J Anesth 25:65-71. 2011
  5. doi request reprint Cardiovascular responses to intravenous injection of a novel isoindolin-1-one derivate in conscious rats
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
    Brain Res 1300:105-13. 2009
  6. ncbi request reprint The effects of propofol on hypothalamic paraventricular nucleus neurons in the rat
    Tetsuro Shirasaka
    Departments of Anesthesiology, Miyazaki Medical College, Kiyotake, Japan
    Anesth Analg 98:1017-23, table of contents. 2004
  7. ncbi request reprint Corticotrophin-releasing factor augments the I(H) in rat hypothalamic paraventricular nucleus parvocellular neurons in vitro
    De lai Qiu
    Department of Physiology, Miyazaki Medical College, University of Miyazaki, 5200 Kihara, Kiyotake cho, Miyazaki gun, Miyazaki 889 1692, Japan
    J Neurophysiol 94:226-34. 2005
  8. ncbi request reprint Neuromedin U receptor-2 mRNA and HCN channels mRNA expression in NMU-sensitive neurons in rat hypothalamic paraventricular nucleus
    De lai Qiu
    Department of Physiology, Miyazaki Medical College, University of Miyazaki, 5200 Kihara, Kiyotake cho, Miyazaki gun, Miyazaki 889 1692, Japan
    Neurosci Lett 374:69-72. 2005
  9. ncbi request reprint [Central action of orexins on sympathetic outflow and cardiovascular function with a focus on the paraventricular nucleus of the hypothalamus]
    Hiroshi Kannan
    Department of Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 889 1692
    Masui 56:30-9. 2007
  10. doi request reprint Clinical dose of lidocaine destroys the cell membrane and induces both necrosis and apoptosis in an identified Lymnaea neuron
    Shin Onizuka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Kiyotake cho, Miyazaki, 889 1692, Japan
    J Anesth 26:54-61. 2012

Collaborators

Detail Information

Publications20

  1. doi request reprint High-dose remifentanil increases blood pressure and heart rate mediated by sympatho-activation in conscious rats
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, 5200 Kihara Kiyotake, Miyazaki, Japan
    J Anesth 27:325-32. 2013
    ..We investigated the effects of an ultra-short-acting μ-opioid receptor agonist, remifentanil, on cardiovascular and sympathetic function in conscious rats...
  2. ncbi request reprint The effects of centrally administered dexmedetomidine on cardiovascular and sympathetic function in conscious rats
    Tetsuro Shirasaka
    Department of Anesthesiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
    Anesth Analg 105:1722-8, table of contents. 2007
    ..In this study, we explored the effects and the mechanism of intracerebroventricularly (icv) administered DEX on cardiovascular responses and sympathetic nerve activity in conscious, unrestrained rats...
  3. ncbi request reprint Activation of a G protein-coupled inwardly rectifying K+ current and suppression of Ih contribute to dexmedetomidine-induced inhibition of rat hypothalamic paraventricular nucleus neurons
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Japan
    Anesthesiology 107:605-15. 2007
    ..The purpose of this study was to examine the effects of dexmedetomidine on the PVN neuron, which is involved in the arginine vasopressin release and autonomic regulation...
  4. doi request reprint Effects of orexin-A on propofol anesthesia in rats
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, 5200 Kihara Kiyotake, Miyazaki 889 1692, Japan
    J Anesth 25:65-71. 2011
    ..Activation of the orexin system induces wakefulness, and inhibition of the orexin system causes narcolepsy. We hypothesized that orexin would affect propofol anesthesia...
  5. doi request reprint Cardiovascular responses to intravenous injection of a novel isoindolin-1-one derivate in conscious rats
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
    Brain Res 1300:105-13. 2009
    ..These results show that the i.v. administration of JM-1232(-) decreased MAP mediated by benzodiazepine-GABA(A) receptors...
  6. ncbi request reprint The effects of propofol on hypothalamic paraventricular nucleus neurons in the rat
    Tetsuro Shirasaka
    Departments of Anesthesiology, Miyazaki Medical College, Kiyotake, Japan
    Anesth Analg 98:1017-23, table of contents. 2004
    ....
  7. ncbi request reprint Corticotrophin-releasing factor augments the I(H) in rat hypothalamic paraventricular nucleus parvocellular neurons in vitro
    De lai Qiu
    Department of Physiology, Miyazaki Medical College, University of Miyazaki, 5200 Kihara, Kiyotake cho, Miyazaki gun, Miyazaki 889 1692, Japan
    J Neurophysiol 94:226-34. 2005
    ..These results suggest that CRF modulates the subpopulation of PVN parvocellular neuronal function by CRF-receptor 1-mediated potentiation of HCN ion channel activity...
  8. ncbi request reprint Neuromedin U receptor-2 mRNA and HCN channels mRNA expression in NMU-sensitive neurons in rat hypothalamic paraventricular nucleus
    De lai Qiu
    Department of Physiology, Miyazaki Medical College, University of Miyazaki, 5200 Kihara, Kiyotake cho, Miyazaki gun, Miyazaki 889 1692, Japan
    Neurosci Lett 374:69-72. 2005
    ..These results suggest that NMU modulates the function of the PVN putative parvocellular neurons and is involved in the regulation of OTergic and VPergic neurons by enhanced HCN ion channels activity via NMU-receptor 2...
  9. ncbi request reprint [Central action of orexins on sympathetic outflow and cardiovascular function with a focus on the paraventricular nucleus of the hypothalamus]
    Hiroshi Kannan
    Department of Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 889 1692
    Masui 56:30-9. 2007
    ..The present studies suggest that PVN plays a role as one of the efferent pathways of orexin-induced activation of the sympathetic outflow...
  10. doi request reprint Clinical dose of lidocaine destroys the cell membrane and induces both necrosis and apoptosis in an identified Lymnaea neuron
    Shin Onizuka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Kiyotake cho, Miyazaki, 889 1692, Japan
    J Anesth 26:54-61. 2012
    ..Using an identified LPeD1 neuron from Lymnaea stagnalis, we sought to determine how lidocaine affects these factors and how lidocaine is related to damage of the cell membrane...
  11. ncbi request reprint Neuromedin U depolarizes rat hypothalamic paraventricular nucleus neurons in vitro by enhancing IH channel activity
    De lai Qiu
    Department of Physiology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    J Neurophysiol 90:843-50. 2003
    ..These results suggest that NMU selectively depolarizes the subpopulation of PVN parvocellular neurons via enhancement of the hyperpolarization-activated inward current...
  12. ncbi request reprint Neuronal effects of orexins: relevant to sympathetic and cardiovascular functions
    Tetsuro Shirasaka
    Department of Anesthesiology, Miyazaki Medical College, 5200 Kihara, Kiyotake, 889 1692, Miyazaki, Japan
    Regul Pept 104:91-5. 2002
    ..This review will focus on the neural effects of orexins and how these peptides may participate in the regulation of cardiovascular and sympathetic functions...
  13. ncbi request reprint Effect of hypertonic saline on rat hypothalamic paraventricular nucleus magnocellular neurons in vitro
    De lai Qiu
    Department of Physiology, Miyazaki Medical College, 5200 Kihara, Kiyotake cho, Miyazaki gun, Miyazaki 889 1692, Japan
    Neurosci Lett 355:117-20. 2004
    ..Hypertonic saline excited PVN magnocellular neurons via osmo-reception, Na+ -detection, and excitatory glutamatergic synaptic input...
  14. doi request reprint Capsaicin indirectly suppresses voltage-gated Na+ currents through TRPV1 in rat dorsal root ganglion neurons
    Shin Onizuka
    Department of Anaesthesiology and Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki 889 1692, Japan
    Anesth Analg 112:703-9. 2011
    ..Therefore, in this study we sought to characterize the effect of capsaicin on tetrodotoxin-sensitive (TTX-s) and resistant (TTX-r) INa(+)...
  15. ncbi request reprint Cardiovascular effects of leptin and orexins
    Tetsuro Shirasaka
    Department of Anesthesiology, Miyazaki Medical College, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    Am J Physiol Regul Integr Comp Physiol 284:R639-51. 2003
    ..The objective of this article is to summarize evidence on the effects of leptin and orexins on cardiovascular function in vivo and in vitro and to discuss the pathophysiological relevance of these peptides and possible interactions...
  16. doi request reprint Lidocaine treatment during synapse reformation periods permanently inhibits NGF-induced excitation in an identified reconstructed synapse of Lymnaea stagnalis
    Shin Onizuka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, Kiyotake cho, Miyazaki, 889 1692, Japan
    J Anesth 26:45-53. 2012
    ....
  17. doi request reprint Effects of landiolol on the cardiovascular response during tracheal extubation
    Tetsuro Shirasaka
    Department of Anesthesiology and Intensive Care, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692, Japan
    J Anesth 22:322-5. 2008
    ..Continuous administration of landiolol, at 0.03 or 0.04 mg x kg(-1) x min(-1), may prevent the increases in HR and RPP, respectively, that occur at the emergence from anesthesia and tracheal extubation...
  18. doi request reprint Involvement of the orexin system in adrenal sympathetic regulation
    Takayuki Nemoto
    Department of Pharmacology, Graduate School of Medicine, University of Miyazaki, Miyazaki, Japan
    Pharmacology 91:250-8. 2013
    ..Our results indicate involvement of the orexin system in the sympathetic regulation of the adrenal medulla...
  19. ncbi request reprint [Anchor Fast endotracheal tube securing device for a pediatric patient during therapeutic hypothermia]
    Takeshi Yano
    Department of Anesthesiology and Critical Care, School of Medicine, University of Miyazaki, Miyazaki 889 1692
    Masui 63:84-7. 2014
    ..Seventy-two hours later, she was rewarmed and extubated as scheduled. Ten days after admission, she was discharged without any neurological deficits...
  20. ncbi request reprint [Optimal dose of fentanyl for postoperative epidural analgesia after cesarean section]
    Tetsuro Shirasaka
    Department of Anesthesiology, Faculty of Medicine, University of Miyazaki, Miyazaki
    Masui 54:1008-13. 2005
    ..The aim of this study was to investigate which dose of fentanyl in ropivacaine for epidural anesthesia will provide effective analgesia with minimal side effects after cesarean section (CS)...