Research Topics
Genomes and GenesSpecies | Aya ShinozakiSummaryAffiliation: University of Tokyo Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Claudin-18 in biliary neoplasms. Its significance in the classification of intrahepatic cholangiocarcinomaAya Shinozaki
Department of Pathology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Virchows Arch 459:73-80. 2011..These results suggest that CLDN18 may play an important role in biliary carcinogenesis, and especially in ICCs, it is associated with aggressive behavior and serves as a useful marker for the classification of ICC...- Expression of ribonucleotide reductase M2 subunit in gastric cancer and effects of RRM2 inhibition in vitroTeppei Morikawa
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Hum Pathol 41:1742-8. 2010..Our data suggest that ribonucleotide reductase M2 subunit overexpression could be associated with the gastric cancer progression and that suppression of its function is a potential therapeutic strategy in gastric cancer... - Downregulation of microRNA-200 in EBV-associated gastric carcinomaAya Shinozaki
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Cancer Res 70:4719-27. 2010.... - SOX9 expression and its methylation status in gastric cancerMinhua Sun
Department of Pathology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
Virchows Arch 460:271-9. 2012..Upregulation of SOX9 is related to GC development. Downregulation by promoter methylation is related to GC progression and EBV infection. SOX9 is closely related to GC carcinogenesis and EBV-associated GC carcinogenesis... 
Transcriptional factor typing with SOX2, HNF4aP1, and CDX2 closely relates to tumor invasion and Epstein-Barr virus status in gastric cancerHiroshi Uozaki
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
Int J Clin Exp Pathol 4:230-40. 2011..Gastric cancer (GC) is a major cancer, sometimes associated with Epstein-Barr virus (EBV). Some transcriptional factors (TFs) are specific to the digestive tract and related to the character of the tumors...- Claudin-18 is an early-stage marker of pancreatic carcinogenesisMariko Tanaka
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Japan
J Histochem Cytochem 59:942-52. 2011..Activation of the PKC pathway might be involved in CLDN18 expression associated with pancreatic carcinogenesis... - Gastric carcinoma with osteoclast-like giant cells. Lymphoepithelioma-like carcinoma with Epstein-Barr virus infection is the predominant typeTetsuo Ushiku
Department of Pathology and Diagnostic Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Pathol Int 60:551-8. 2010..Both LELC and no-LELC types were also suggested to have better prognoses, but the behavior of the GCT type needs to be further characterized... - Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinomaRumi Hino
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
Cancer Res 69:2766-74. 2009..LMP2A plays an essential role in the epigenetic abnormalities in host stomach cells and in the development and maintenance of EBV-associated cancer... - Prominent Mott cell proliferation in Epstein-Barr virus-associated gastric carcinomaAya Shinozaki
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113 0033, Japan
Hum Pathol 41:134-8. 2010..The differential diagnosis included primary gastric lymphoma and nonneoplastic conditions such as Russell body gastritis; EBER in situ hybridization was helpful in their differentiation... - Glypican 3-expressing gastric carcinoma: distinct subgroup unifying hepatoid, clear-cell, and alpha-fetoprotein-producing gastric carcinomasTetsuo Ushiku
Department of Pathology and Diagnostic Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Cancer Sci 100:626-32. 2009..GPC3-GC is a distinctive group of GC, which unifies hepatoid, clear-cell, and alpha-fetoprotein-producing GC. GPC3 is expected to be a target of forthcoming immunotherapy for a patient bearing this specific type of GC... - Composite diffuse large B-cell lymphoma and CD20-positive peripheral T-cell lymphomaSho Yamazaki
Department of Hematology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Pathol Int 61:662-6. 2011..Moreover, a literature review of composite DLBCL and PTCL-NOS indicates that this rare clinical entity may be featured by efficacy of systemic chemotherapy in spite of prevalent extranodal lesions... - Hyperbilirubinemia after hematopoietic stem cell transplantation: comparison of clinical and pathologic findings in 41 autopsied casesYuki Kagoya
Department of Hematology and Oncology, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
Clin Transplant 25:E552-7. 2011..Although analysis of clinical data is useful for narrowing diagnosis, histological analysis by liver biopsy is crucially important, especially in cases suspected of having GVHD... - Epstein-Barr virus-associated gastric carcinoma: a distinct carcinoma of gastric phenotype by claudin expression profilingAya Shinozaki
Department of Pathology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
J Histochem Cytochem 57:775-85. 2009..EBV-associated GC may undergo distinct carcinogenic processes, which differ from those of EBV-negative GC...