Shinichi Shimizu

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. doi request reprint Use of implanted markers and interportal adjustment with real-time tracking radiotherapy system to reduce intrafraction prostate motion
    Shinichi Shimizu
    Department of Radiation Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 81:e393-9. 2011
  2. ncbi request reprint Can hybrid FDG-PET/CT detect subclinical lymph node metastasis of esophageal cancer appropriately and contribute to radiation treatment planning? A comparison of image-based and pathological findings
    Shinichi Shimizu
    Department of Radiology, Hokkaido University, Graduate School of Medicine, Kita ku, Sapporo, Japan
    Int J Clin Oncol 14:421-5. 2009
  3. ncbi request reprint Tumor location, cirrhosis, and surgical history contribute to tumor movement in the liver, as measured during stereotactic irradiation using a real-time tumor-tracking radiotherapy system
    Kei Kitamura
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 56:221-8. 2003
  4. pmc Stereotactic body radiotherapy using gated radiotherapy with real-time tumor-tracking for stage I non-small cell lung cancer
    Tetsuya Inoue
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Radiat Oncol 8:69. 2013
  5. ncbi request reprint Reduction in acute morbidity using hypofractionated intensity-modulated radiation therapy assisted with a fluoroscopic real-time tumor-tracking system for prostate cancer: preliminary results of a phase I/II study
    Kei Kitamura
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Cancer J 9:268-76. 2003
  6. ncbi request reprint Real-time tumor-tracking radiotherapy for adrenal tumors
    Norio Katoh
    Department of Radiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Radiother Oncol 87:418-24. 2008
  7. pmc Dose-volume analysis for respiratory toxicity in intrathoracic esophageal cancer patients treated with definitive chemoradiotherapy using extended fields
    Satoshi Tanabe
    Department of Radiation Oncology, Keiyukai Sapporo Hospital, 1 1, 14 chome, Hondori, Shiroishi ku, Sapporo, 003 0027, Japan
    J Radiat Res 54:1085-94. 2013
  8. pmc What is the appropriate size criterion for proton radiotherapy for hepatocellular carcinoma? A dosimetric comparison of spot-scanning proton therapy versus intensity-modulated radiation therapy
    Chie Toramatsu
    Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Radiat Oncol 8:48. 2013
  9. doi request reprint Integration of a real-time tumor monitoring system into gated proton spot-scanning beam therapy: an initial phantom study using patient tumor trajectory data
    Taeko Matsuura
    Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, 060 8638, Japan
    Med Phys 40:071729. 2013
  10. ncbi request reprint Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy
    Mikado Imura
    First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 63:1442-7. 2005

Collaborators

Detail Information

Publications34

  1. doi request reprint Use of implanted markers and interportal adjustment with real-time tracking radiotherapy system to reduce intrafraction prostate motion
    Shinichi Shimizu
    Department of Radiation Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 81:e393-9. 2011
    ..The incidence of table position adjustment required to keep intrafractional uncertainty within 2.0 mm was investigated in this study...
  2. ncbi request reprint Can hybrid FDG-PET/CT detect subclinical lymph node metastasis of esophageal cancer appropriately and contribute to radiation treatment planning? A comparison of image-based and pathological findings
    Shinichi Shimizu
    Department of Radiology, Hokkaido University, Graduate School of Medicine, Kita ku, Sapporo, Japan
    Int J Clin Oncol 14:421-5. 2009
    ....
  3. ncbi request reprint Tumor location, cirrhosis, and surgical history contribute to tumor movement in the liver, as measured during stereotactic irradiation using a real-time tumor-tracking radiotherapy system
    Kei Kitamura
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 56:221-8. 2003
    ..To investigate the three-dimensional (3D) intrafractional motion of liver tumors during real-time tumor-tracking radiotherapy (RTRT)...
  4. pmc Stereotactic body radiotherapy using gated radiotherapy with real-time tumor-tracking for stage I non-small cell lung cancer
    Tetsuya Inoue
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Radiat Oncol 8:69. 2013
    ..To clarify the clinical outcomes of two dose schedule of stereotactic body radiotherapy (SBRT) for stage I non-small cell lung cancer (NSCLC) using a real-time tumor-tracking radiation therapy (RTRT) system in single institution...
  5. ncbi request reprint Reduction in acute morbidity using hypofractionated intensity-modulated radiation therapy assisted with a fluoroscopic real-time tumor-tracking system for prostate cancer: preliminary results of a phase I/II study
    Kei Kitamura
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Cancer J 9:268-76. 2003
    ..The acute radiation reaction and preliminary tumor response of prostate cancer to hypofractionated intensity-modulated radiation therapy assisted with real-time tumor-tracking radiation therapy were investigated in this study...
  6. ncbi request reprint Real-time tumor-tracking radiotherapy for adrenal tumors
    Norio Katoh
    Department of Radiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Radiother Oncol 87:418-24. 2008
    ....
  7. pmc Dose-volume analysis for respiratory toxicity in intrathoracic esophageal cancer patients treated with definitive chemoradiotherapy using extended fields
    Satoshi Tanabe
    Department of Radiation Oncology, Keiyukai Sapporo Hospital, 1 1, 14 chome, Hondori, Shiroishi ku, Sapporo, 003 0027, Japan
    J Radiat Res 54:1085-94. 2013
    ....
  8. pmc What is the appropriate size criterion for proton radiotherapy for hepatocellular carcinoma? A dosimetric comparison of spot-scanning proton therapy versus intensity-modulated radiation therapy
    Chie Toramatsu
    Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Radiat Oncol 8:48. 2013
    ....
  9. doi request reprint Integration of a real-time tumor monitoring system into gated proton spot-scanning beam therapy: an initial phantom study using patient tumor trajectory data
    Taeko Matsuura
    Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, 060 8638, Japan
    Med Phys 40:071729. 2013
    ..The clinically acceptable range of adjustable irradiation control parameters was explored. Also, the relation between the dose error and the characteristics of tumor motion was investigated...
  10. ncbi request reprint Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy
    Mikado Imura
    First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 63:1442-7. 2005
    ....
  11. ncbi request reprint Intrafractional tumor motion: lung and liver
    Hiroki Shirato
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Semin Radiat Oncol 14:10-8. 2004
    ..This article reviews the current basic knowledge on respiratory physiology and summarizes the accumulating knowledge on internal motion of lung and liver tumors...
  12. pmc Early results of urethral dose reduction and small safety margin in intensity-modulated radiation therapy (IMRT) for localized prostate cancer using a real-time tumor-tracking radiotherapy (RTRT) system
    Shinichi Shimizu
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Radiat Oncol 9:118. 2014
    ....
  13. ncbi request reprint Tolerance of organs at risk in small-volume, hypofractionated, image-guided radiotherapy for primary and metastatic lung cancers
    Rikiya Onimaru
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 56:126-35. 2003
    ..To determine the organ at risk and the maximum tolerated dose (MTD) of radiation that could be delivered to lung cancer using small-volume, image-guided radiotherapy (IGRT) using hypofractionated, coplanar, and noncoplanar multiple fields...
  14. pmc Prospective phase II study of image-guided local boost using a real-time tumor-tracking radiotherapy (RTRT) system for locally advanced bladder cancer
    Kentaro Nishioka
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine School of Medicine, Sapporo, Japan
    Jpn J Clin Oncol 44:28-35. 2014
    ....
  15. ncbi request reprint Registration accuracy and possible migration of internal fiducial gold marker implanted in prostate and liver treated with real-time tumor-tracking radiation therapy (RTRT)
    Kei Kitamura
    Department of Radiology, Hokkaido University School of Medicine, North 15 West 7, Kita ku, Sapporo 060 8638, Japan
    Radiother Oncol 62:275-81. 2002
    ..The registration accuracy and possible migration of the internal fiducial gold marker implanted into prostate and liver was investigated...
  16. ncbi request reprint Three-dimensional conformal setup (3D-CSU) of patients using the coordinate system provided by three internal fiducial markers and two orthogonal diagnostic X-ray systems in the treatment room
    Hiroki Shirato
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 60:607-12. 2004
    ..We call this system "three-dimensional conformal setup" (3D-CSU)...
  17. doi request reprint A new brain positron emission tomography scanner with semiconductor detectors for target volume delineation and radiotherapy treatment planning in patients with nasopharyngeal carcinoma
    Norio Katoh
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 82:e671-6. 2012
    ....
  18. doi request reprint Three-dimensional intrafractional motion of breast during tangential breast irradiation monitored with high-sampling frequency using a real-time tumor-tracking radiotherapy system
    Rumiko Kinoshita
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 70:931-4. 2008
    ..To evaluate the three-dimensional intrafraction motion of the breast during tangential breast irradiation using a real-time tracking radiotherapy (RT) system with a high-sampling frequency...
  19. doi request reprint Optimization of fluoroscopy parameters using pattern matching prediction in the real-time tumor-tracking radiotherapy system
    Naoki Miyamoto
    Division of Medical Physics and Engineering, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    Phys Med Biol 56:4803-13. 2011
    ..The result shows that the proposed prediction method is expected to be applicable in a real clinical situation...
  20. doi request reprint Dosimetric comparison between intensity-modulated radiotherapy and standard wedged tangential technique for whole-breast radiotherapy in Asian women with relatively small breast volumes
    Kazuhiko Tsuchiya
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, North 15 West 7 Kita Ku, Sapporo, 060 8638, Japan
    Radiol Phys Technol 7:67-72. 2014
    ..001) and to the contralateral lung (p < 0.001). Tangential-field IMRT provided an improved dose distribution compared with SWT for WBRT in Asian women with a relatively small breast volume...
  21. pmc Evaluation of inter-observer variability of bladder boundary delineation on cone-beam CT
    Kentaro Nishioka
    Department of Radiation Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Radiat Oncol 8:185. 2013
    ..The aim of this work was to analyze and evaluate the inter-observer contouring uncertainties of bladder boundary delineation on CBCT images in a prospective fashion...
  22. pmc A proton beam therapy system dedicated to spot-scanning increases accuracy with moving tumors by real-time imaging and gating and reduces equipment size
    Shinichi Shimizu
    Department of Radiation Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan
    PLoS ONE 9:e94971. 2014
    ..The dose distribution and treatment time of the newly designed real-time-image gated, spot-scanning proton beam therapy (RGPT) were compared with free-breathing spot-scanning proton beam therapy (FBPT) in a simulation...
  23. ncbi request reprint Organ motion in image-guided radiotherapy: lessons from real-time tumor-tracking radiotherapy
    Hiroki Shirato
    Division of Radiation Oncology, Department of Radiology, Hokkaido University School of Medicine, North 15 West 7, Kita ku, 060 8638 Sapporo, Japan
    Int J Clin Oncol 12:8-16. 2007
    ..Lung, liver, prostate, spinal/paraspinal, gynecological, head and neck, esophagus, and pancreas tumors are now ready for dose escalation studies using RTRT...
  24. ncbi request reprint Biological effect of dose distortion by fiducial markers in spot-scanning proton therapy with a limited number of fields: a simulation study
    Taeko Matsuura
    Department of Medical Physics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan
    Med Phys 39:5584-91. 2012
    ..This paper focuses on prostate cancer and explores the possibility that multiple-field irradiation improves the underdose effect by markers on tumor-control probability (TCP)...
  25. ncbi request reprint Three-dimensional intrafractional movement of prostate measured during real-time tumor-tracking radiotherapy in supine and prone treatment positions
    Kei Kitamura
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 53:1117-23. 2002
    ..To quantify three-dimensional (3D) movement of the prostate gland with the patient in the supine and prone positions and to analyze the movement frequency for each treatment position...
  26. ncbi request reprint Real-time tumor-tracking radiation therapy for lung carcinoma by the aid of insertion of a gold marker using bronchofiberscopy
    Toshiyuki Harada
    First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan
    Cancer 95:1720-7. 2002
    ..The purpose of the current study was to evaluate RTRT's feasibility in lung carcinoma treatment...
  27. pmc High dose three-dimensional conformal boost using the real-time tumor tracking radiotherapy system in cervical cancer patients unable to receive intracavitary brachytherapy
    Hee Chul Park
    Department of Radiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    Yonsei Med J 51:93-9. 2010
    ..The purpose of this study is to evaluate the clinical results of treatment with a high dose of 3-dimensional conformal boost (3DCB) using a real-time tracking radiation therapy (RTRT) system in cervical cancer patients...
  28. doi request reprint Clinical outcomes of stereotactic body radiotherapy for small lung lesions clinically diagnosed as primary lung cancer on radiologic examination
    Tetsuya Inoue
    Department of Radiology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita ku, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 75:683-7. 2009
    ..The aim of the present study was to evaluate the outcome of stereotactic body radiotherapy (SBRT) for small lung lesions that were clinically diagnosed as primary lung cancer without pathologic confirmation...
  29. doi request reprint Real-time 4-D radiotherapy for lung cancer
    Hiroki Shirato
    Department of Radiation Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan
    Cancer Sci 103:1-6. 2012
    ..Real-time tumor tracking via spot-scanning proton beam therapy has the capability to cure large lung cancers in motion, and is expected to be the next-generation real-time 4DRT...
  30. ncbi request reprint Real-time monitoring of a digestive tract marker to reduce adverse effects of moving organs at risk (OAR) in radiotherapy for thoracic and abdominal tumors
    Takayuki Hashimoto
    Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
    Int J Radiat Oncol Biol Phys 61:1559-64. 2005
    ..To evaluate the feasibility of real-time monitoring of a fiducial marker in/near the digestive tract and to analyze the motion of organs at risk to determine a reasonable internal margin...
  31. pmc Co-overexpression of GEP100 and AMAP1 proteins correlates with rapid local recurrence after breast conservative therapy
    Rumiko Kinoshita
    Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan
    PLoS ONE 8:e76791. 2013
    ..We also discuss why mRNAs encoding these proteins have not been identified to correlate with local recurrence by previous conventional gene expression profiling analyses. ..
  32. doi request reprint Efficacy of therapy for advanced hepatocellular carcinoma: intra-arterial 5-fluorouracil and subcutaneous interferon with image-guided radiation
    Makoto Chuma
    Department of Gastroenterology and Hematology, Hokkaido University, Sapporo, Japan
    J Gastroenterol Hepatol 26:1123-32. 2011
    ..To evaluate the efficacy of intra-arterial 5-fluorouracil (5-FU) and subcutaneous interferon (IFN) combined with image-guided radiation therapy (IGRT) in advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT)...
  33. ncbi request reprint MR imaging of primary malignant lymphoma of the pancreas
    Takayuki Masui
    Department of Radiology, Seirei Hamamatsu General Hospital, Hamamatsu 430 8558, Japan
    Radiat Med 23:213-5. 2005
    ..The infiltrative nature and hypovascularity in early-phase dynamic contrast study without encasement of arteries and veins were well demonstrated by MR imaging and were consistent with malignant lymphoma...
  34. ncbi request reprint Exophytic giant cavernous hemangioma of the liver with growing tendency
    Takayuki Masui
    Department of Radiology, Seirei Hamamatsu General Hospital, Shizuoka, Japan
    Radiat Med 23:121-4. 2005
    ..We report a case of exophytic hemangioma of the liver with a growing tendency, demonstrated using magnetic resonance imaging (MRI) and computed tomography (CT) combined with angiography...