Hajime Sato

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint [Policy science and health policy]
    H Sato
    Department of Public Health, Graduate School of Medicine, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Nihon Eiseigaku Zasshi 56:561-70. 2001
  2. ncbi request reprint Politics of leprosy segregation in Japan: the emergence, transformation and abolition of the patient segregation policy
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, 113 0033, Tokyo, Japan
    Soc Sci Med 56:2529-39. 2003
  3. ncbi request reprint Agenda setting for smoking control in Japan, 1945-1990: influence of the mass media on national health policy making
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Health Commun 8:23-40. 2003
  4. pmc Countermeasures and vaccination against terrorism using smallpox: pre-event and post-event smallpox vaccination and its contraindications
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo ku, Japan
    Environ Health Prev Med 16:281-9. 2011
  5. pmc The public acceptance of smallpox vaccination to fight bioterrorism in Japan: results of a large-scale opinion survey in Japan
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo ku, Japan
    Environ Health Prev Med 16:290-8. 2011
  6. ncbi request reprint [History of Hansen's disease control policy in the United States]
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Nihon Hansenbyo Gakkai Zasshi 74:23-41. 2005
  7. ncbi request reprint Influence of monopoly privatization and market liberalization on smoking prevalence in Japan: trends of smoking prevalence in Japan in 1975-1995
    H Sato
    Department of Public Health and Occupational Medicine, Graduate School of Medicine, University of Tokyo, Japan
    Addiction 95:1079-88. 2000
  8. ncbi request reprint [Social consensus on medical technology policy: ethical issues and citizen participation]
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Nihon Eiseigaku Zasshi 59:12-22. 2004
  9. ncbi request reprint Appraisal of the policymaking process in Japan for gene therapy: results of national surveys of academic societies, hospitals, and medical schools
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Med Sci Monit 12:PH7-15. 2006
  10. ncbi request reprint Public, experts, and acceptance of advanced medical technologies: the case of organ transplant and gene therapy in Japan
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Health Care Anal 14:203-14. 2006

Detail Information

Publications68

  1. ncbi request reprint [Policy science and health policy]
    H Sato
    Department of Public Health, Graduate School of Medicine, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Nihon Eiseigaku Zasshi 56:561-70. 2001
    ..In addition to the main topics in the field, empirical studies, from Japan or from other countries, are also summarized. Finally, future research needs and expectations are addressed...
  2. ncbi request reprint Politics of leprosy segregation in Japan: the emergence, transformation and abolition of the patient segregation policy
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, 113 0033, Tokyo, Japan
    Soc Sci Med 56:2529-39. 2003
    ..To make policies reflective of scientific knowledge, it is essential to understand and foresee the effect of policy legacy, when introducing and appraising public health policies...
  3. ncbi request reprint Agenda setting for smoking control in Japan, 1945-1990: influence of the mass media on national health policy making
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Health Commun 8:23-40. 2003
    ....
  4. pmc Countermeasures and vaccination against terrorism using smallpox: pre-event and post-event smallpox vaccination and its contraindications
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo ku, Japan
    Environ Health Prev Med 16:281-9. 2011
    ..Public health professionals, as well as physicians and government officials, should also be well equipped with all information necessary for appropriate and effective smallpox management in the face of such a bioterrorism attack...
  5. pmc The public acceptance of smallpox vaccination to fight bioterrorism in Japan: results of a large-scale opinion survey in Japan
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo ku, Japan
    Environ Health Prev Med 16:290-8. 2011
    ..This study examines the public acceptance of smallpox vaccinations in the event of a terrorist attack using smallpox. The article also provides public health professionals with the information necessary for such smallpox management...
  6. ncbi request reprint [History of Hansen's disease control policy in the United States]
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Nihon Hansenbyo Gakkai Zasshi 74:23-41. 2005
    ..It was in 1985 when the Act was abolished. Provision of long-term care for new patients at the Center was terminated finally in 1997...
  7. ncbi request reprint Influence of monopoly privatization and market liberalization on smoking prevalence in Japan: trends of smoking prevalence in Japan in 1975-1995
    H Sato
    Department of Public Health and Occupational Medicine, Graduate School of Medicine, University of Tokyo, Japan
    Addiction 95:1079-88. 2000
    ..In the mid-1980s, the public tobacco monopoly was privatized and the tobacco market was liberalized in Japan. This study examines whether the trends in smoking prevalence changed at the time of these market changes...
  8. ncbi request reprint [Social consensus on medical technology policy: ethical issues and citizen participation]
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Nihon Eiseigaku Zasshi 59:12-22. 2004
    ..Finally, the paper discusses some of the future agendas on this issue...
  9. ncbi request reprint Appraisal of the policymaking process in Japan for gene therapy: results of national surveys of academic societies, hospitals, and medical schools
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Med Sci Monit 12:PH7-15. 2006
    ..Appraisals of these guidelines were obtained from academic societies, institutional review boards (IRBs) of hospitals, and ethics committees (ECs) at medical schools nationwide...
  10. ncbi request reprint Public, experts, and acceptance of advanced medical technologies: the case of organ transplant and gene therapy in Japan
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Health Care Anal 14:203-14. 2006
    ....
  11. ncbi request reprint Policy and politics of smoking control in Japan
    H Sato
    Department of Public Health and Occupational Medicine, Graduate School of Medicine, University of Tokyo, Japan
    Soc Sci Med 49:581-600. 1999
    ..Consequently, they have been mostly ineffective in decreasing the prevalence of smoking among the populace. Clearly, leadership by the health ministry coupled with political support are the key to advancing effective smoking control...
  12. doi request reprint Cardiac surgery in patients with trisomy 18
    Yukihiro Kaneko
    Department of Cardiovascular Surgery, Japanese Red Cross Medical Center, Tokyo, Japan
    Pediatr Cardiol 30:729-34. 2009
    ..Only one patient died of heart failure, suggesting that cardiac surgery was effective in preventing heart failure-related death...
  13. doi request reprint Alcohol consumption is inversely correlated with insulin resistance, independent of metabolic syndrome factors and fatty liver diseases
    Toshiaki Gunji
    Center for Preventive Medicine, Kanto Medical Center, University of Tokyo, Tokyo, Japan
    J Clin Gastroenterol 45:808-13. 2011
    ..The role of alcohol consumption in insulin resistance remains unclear. The aim of this study was to examine the association between alcohol consumption and insulin resistance in a large asymptomatic population...
  14. doi request reprint Helicobacter pylori infection is significantly associated with metabolic syndrome in the Japanese population
    Toshiaki Gunji
    Center for Preventive Medicine, Kanto Medical Canter, NTT East, Tokyo, Japan
    Am J Gastroenterol 103:3005-10. 2008
    ..Metabolic syndrome comprises a cluster of metabolic abnormalities leading to insulin resistance and atherosclerosis, and Helicobacter pylori is thought to be a contributing factor...
  15. ncbi request reprint Modest alcohol consumption has an inverse association with liver fat content
    Toshiaki Gunji
    Center for Preventive Medicine, NTT Medical Center Tokyo, Tokyo, Japan
    Hepatogastroenterology 59:2552-6. 2012
    ..We aimed to explore the association between alcohol consumption and liver fat content as quantitative-ly determined by computed tomography (CT)...
  16. doi request reprint Risk factors for erosive esophagitis: a cross-sectional study of a large number of Japanese males
    Toshiaki Gunji
    Center for Preventive Medicine, Kanto Medical Center, NTT East, Tokyo, Japan
    J Gastroenterol 46:448-55. 2011
    ..We undertook this study, with a large sample size, to investigate risk factors for endoscopic erosive esophagitis by multivariate analysis, including visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) as covariates...
  17. pmc Public appraisal of government efforts and participation intent in medico-ethical policymaking in Japan: a large scale national survey concerning brain death and organ transplant
    Hajime Sato
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    BMC Med Ethics 6:E1. 2005
    ..On the other hand, public involvement is required if effective policy is to be developed and accepted...
  18. pmc Disparity in disaster preparedness among rheumatoid arthritis patients with various general health, functional, and disability conditions
    Jun Tomio
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Environ Health Prev Med 17:322-31. 2012
    ....
  19. doi request reprint Risk factors for serum alanine aminotransferase elevation: A cross-sectional study of healthy adult males in Tokyo, Japan
    Toshiaki Gunji
    Center for Preventive Medicine, Kanto Medical Center, NTT East, Tokyo, Japan
    Dig Liver Dis 42:882-7. 2010
    ..Liver-protective effects of light-to-moderate alcohol consumption have been suggested...
  20. doi request reprint A five year follow-up national study of ethics committees in medical organizations in Japan
    Akira Akabayashi
    Department of Biomedical Ethics, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    HEC Forum 20:49-60. 2008
  21. pmc Delay in the treatment of pulmonary tuberculosis: a report from Afghanistan
    Wrishmeen Sabawoon
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 0033, Japan
    Environ Health Prev Med 17:53-61. 2012
    ....
  22. pmc An eight-year follow-up national study of medical school and general hospital ethics committees in Japan
    Akira Akabayashi
    Department of Biomedical Ethics, Graduate School of Medicine University of Tokyo University of Tokyo 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    BMC Med Ethics 8:8. 2007
    ..The purpose of this study was to describe the characteristics and developments of ethics committees established at medical schools and general hospitals in Japan...
  23. doi request reprint Impact of natural disasters on the functional and health status of patients with rheumatoid arthritis
    Jun Tomio
    Department of Public Health, Graduate School of Medicine, The University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo, 113 0033, Japan
    Mod Rheumatol 21:381-90. 2011
    ..Based on these results, we conclude that the functional and health status of women RA patients could worsen due to the consequences of a natural disaster, with a disproportionately large impact upon those with a poorer functional status...
  24. ncbi request reprint Does preoperative transbronchial biopsy worsen the postsurgical prognosis of lung cancer? A propensity score-adjusted analysis
    Jun Nakajima
    Department of Cardiothoracic Surgery, Graduate School of Medicine, University of Tokyo, Japan
    Chest 128:3512-8. 2005
    ....
  25. ncbi request reprint Effectiveness of combined blood conservation measures in thoracic aortic operations with deep hypothermic circulatory arrest
    Ko Shibata
    Department of Cardiothoracic Surgery, University of Tokyo, Japan
    Ann Thorac Surg 73:739-43; discussion 743-4. 2002
    ..The effectiveness of blood conservation measures for thoracic aortic operations with deep hypothermic circulatory arrest has not yet been documented...
  26. ncbi request reprint Chronic active desease refext cancer riski in ulcreative collitis
    M Shinozaki
    Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo
    Jpn J Cancer Res 90:1066-70. 1999
    ..Multivariate analysis revealed two significant factors: duration of diarrhea (P<0.001) and age at onset (P<0.01). Chronic active disease is a risk factor for colorectal cancer or dysplasia in extensive and longstanding UC...
  27. ncbi request reprint Doppler ultrasonographic identification of the critical segmental artery for spinal cord protection
    K Shibata
    Department of Cardiothoracic Surgery, University of Tokyo, 7 3 1 Hongo Bunkyo ku, 113 8655, Tokyo, Japan
    Eur J Cardiothorac Surg 20:527-32. 2001
    ..The purpose of this study is to evaluate the possibility of identifying critical segmental arteries (CSAs) based on Doppler ultrasonographic hemodynamics...
  28. ncbi request reprint Correlation between neurotoxic events and intracerebral concentration of tacrolimus in rats
    Y Sakamoto
    Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan
    Biol Pharm Bull 23:1008-10. 2000
    ....
  29. ncbi request reprint Interruption of medication among outpatients with chronic conditions after a flood
    Jun Tomio
    Department of Public Health, Graduate School of Medicine, The University of Tokyo
    Prehosp Disaster Med 25:42-50. 2010
    ..The aims of this study are to describe the prevalence of the interruption of medication among the outpatients in the flood-affected area and to determine the risk and preventive factors for the interruption of medication...
  30. ncbi request reprint Neurocognitive outcome after retrograde cerebral perfusion
    Takeshi Miyairi
    Department of Cardiothoracic Surgery, University of Tokyo, Tokyo, Japan
    Ann Thorac Surg 77:1630-3; discussion 1635. 2004
    ..Neurocognitive outcome in patients undergoing thoracic aortic surgery using retrograde cerebral perfusion (RCP) remains uncertain...
  31. ncbi request reprint Experience with diphtheria toxoid-tetanus toxoid-acellular pertussis vaccine in Japan
    H Sato
    National Institute of Health, Tokyo, Japan
    Clin Infect Dis 28:S124-30. 1999
    ..To control pertussis, booster vaccination with diphtheria toxoid-tetanus toxoid-acellular pertussis vaccine in adults should be considered...
  32. pmc Simple preoperative computed tomography image analysis shows good predictive performance for pathological vessel invasion in clinical stage IA non-small cell lung cancer
    Takuya Ito
    Department of Thoracic Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Interact Cardiovasc Thorac Surg 15:633-8. 2012
    ..We evaluated the importance of vessel invasion as a prognostic factor in clinical stage IA non-small cell lung cancer and predictive performance of simple diameter-based computed tomography image analysis for vessel invasion...
  33. doi request reprint Helicobacter pylori infection significantly increases insulin resistance in the asymptomatic Japanese population
    Toshiaki Gunji
    Center for Preventive Medicine, Kanto Medical Center, NTT East, Tokyo, Japan
    Helicobacter 14:144-50. 2009
    ..Insulin resistance is the pathophysiologic background of the clinical features of atherosclerosis and cardiovascular diseases. We examined the association between H. pylori infection and insulin resistance in a large Japanese population...
  34. doi request reprint Intensive cardiac management in patients with trisomy 13 or trisomy 18
    Yukihiro Kaneko
    Department of Cardiovascular Surgery, Japanese Red Cross Medical Center, Tokyo, Japan
    Am J Med Genet A 146:1372-80. 2008
    ..Therefore, we suggest that this approach is a treatment option for cardiac lesions associated with these trisomies. These data are helpful for clinicians and families to consider in the optimal treatment of patients with these trisomies...
  35. ncbi request reprint Higher intracerebral concentration of tacrolimus after intermittent than continuous administration to rats
    Y Sakamoto
    Division of Surgery, Artificial Organ and Transplantation Surgery, Graduate School of Medicine, University of Tokyo, Japan
    Liver Transpl 7:1071-6. 2001
    ..Continuous administration of tacrolimus might be more advantageous than the intermittent method to reduce the intracerebral concentration and neurotoxicity...
  36. ncbi request reprint Myasthenia gravis accompanied by alopecia areata: clinical and immunogenetic aspects
    S Suzuki
    Department of Neurology, Keio University School of Medicine, Shinanomachi, Tokyo, Japan
    Eur J Neurol 12:566-70. 2005
    ..In conclusion, a subset of MG patients who have severe neuromuscular symptoms and thymoma develop AA several years after thymectomy...
  37. ncbi request reprint Quantitative relationship between myocardial concentration of tacrolimus and QT prolongation in guinea pigs: pharmacokinetic/pharmacodynamic model incorporating a site of adverse effect
    T Minematsu
    Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Japan
    J Pharmacokinet Pharmacodyn 28:533-54. 2001
    ..Such a hysteresis pattern for QTprolongation might be caused, therefore, mainly by the delayed disposition of FK506 to ventricular myocytes...
  38. ncbi request reprint Effect of hematocrit on pharmacokinetics of tacrolimus in adult living donor liver transplant recipients
    T Minematsu
    Department of Pharmacy, University of Tokyo Hospital, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Transplant Proc 36:1506-11. 2004
    ..Because FK506 highly and saturably binds in blood cells, a change in hematocrit value (Hct) may affect FK506 pharmacokinetics. Therefore, we investigated effects of Hct on FK506 pharmacokinetics...
  39. ncbi request reprint Effects of safety behaviours with pesticide use on occurrence of acute symptoms in male and female tobacco-growing Malaysian farmers
    Rusli Bin Nordi
    Department of Public Health and Occupational Medicine, Graduate School of Medicine, The University of Tokyo, Japan
    Ind Health 40:182-90. 2002
    ..Safety behaviours in pesticide use in male and female tobacco-growing farmers are discussed in the light of these findings...
  40. ncbi request reprint Thymoma associated with pure red-cell aplasia: clinical features and prognosis
    Tomohiro Murakawa
    Department of Cardiothoracic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Asian Cardiovasc Thorac Ann 10:150-4. 2002
    ..The possible onset of pure red-cell aplasia after thymectomy should be kept in mind during follow-up...
  41. ncbi request reprint Comparison of neurocognitive results after coronary artery bypass grafting and thoracic aortic surgery using retrograde cerebral perfusion
    Takeshi Miyairi
    Department of Cardiothoracic Surgery, University of Tokyo, Tokyo, Japan
    Eur J Cardiothorac Surg 28:97-101; discussion 102-3. 2005
    ..It remains unclear whether RCP provides improved neurological and neuropsychological outcome...
  42. ncbi request reprint The limiting factors for the transxiphoid approach in congenital cardiac surgery
    Kagami Miyaji
    Department of Cardiothoracic Surgery, University of Tokyo Hospital, Tokyo, Japan
    Heart Surg Forum 7:E250-3. 2004
    ..However, this approach cannot be performed for all patients because of the small "xiphoid window." We analyzed the factors limiting this approach to determine the best factor predicting risk...
  43. ncbi request reprint In vitro activation of the corticosteroid ciclesonide in animal nasal mucosal homogenates
    H Sato
    Teijin Institute for Biomedical Research, Teijin Pharma Limited, Tokyo, Japan
    Biopharm Drug Dispos 28:59-64. 2007
    ..5 micromol/l and 5 micromol/l, respectively. This study confirms that ciclesonide is converted to des-CIC in nasal mucosal homogenates without any marked differences among animal species...
  44. doi request reprint Cardiovascular event rates in patients with cerebrovascular disease and atherothrombosis at other vascular locations: results from 1-year outcomes in the Japanese REACH Registry
    Shinichiro Uchiyama
    Department of Neurology, Tokyo Women s Medical University School of Medicine, Tokyo, Japan
    J Neurol Sci 287:45-51. 2009
    ..9 were significant predisposing factors for stroke. Patients with CVD and co-existing atherothrombotic diseases had a high risk of recurrent events, including events arising in other vascular beds than originally diagnosed...
  45. ncbi request reprint Induction of bronchial hyperresponsiveness by Bordetella bronchiseptica infection in dogs
    H Nishikata
    Showa University, School of Medicine, Tokyo, Japan
    Ann Allergy 62:51-8. 1989
    ..Thus, it is speculated that airway epithelial damage and effects on ciliostatic function induced by the organism are primarily involved in the pathogenesis...
  46. ncbi request reprint [Protective effects of naftidrofuryl oxalate against hypoxia-induced death]
    J Hayashi
    Department of Medicine and Gerontology, School of Medicine, Kyorin University, Tokyo, Japan
    Nihon Yakurigaku Zasshi 99:247-54. 1992
    ..Neither idebenone (10 mg/kg) nor nicergoline (10 mg/kg) showed significant changes in survival duration. These findings suggest that LS-121, either with or without BI, could improve cerebrovascular disorders induced by hypoxia...
  47. ncbi request reprint Three-field lymph node dissection for esophageal cancer in elderly patients over 70 years of age
    W Fang
    Department of Surgery, National Cancer Center Hospital, Tokyo, Japan
    Ann Thorac Surg 72:867-71. 2001
    ..For elderly patients with multiorgan dysfunction, however, less invasive procedures might be more appropriate...
  48. ncbi request reprint Predictive risk factors for delayed extubation in patients undergoing coronary artery bypass grafting
    Y Suematsu
    Department of Cardiothoracic Surgery, University of Tokyo, Japan
    Heart Vessels 15:214-20. 2000
    ..Moreover, the PaO2/FiO2 ratio may be a useful predictor of delayed extubation in patients undergoing CABG...
  49. ncbi request reprint Polymorphism in the promoter of lipopolysaccharide receptor CD14 and ischemic cerebrovascular disease
    D Ito
    Department of Neurology, School of Medicine, Keio University, Tokyo, Japan
    Stroke 31:2661-4. 2000
    ..In the present study we investigated a possible association between the C(-260)-->T polymorphism in the CD14 promoter and the occurrence of symptomatic ischemic cerebrovascular disease (CVD)...
  50. ncbi request reprint Relationship between total and regional bone mineral density and menopausal state, body composition and life style factors in overweight Japanese women
    J S Lee
    Department of Health Economics and Health Promotion Sciences, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Int J Obes Relat Metab Disord 25:880-6. 2001
    ..To investigate whether menopausal state, body composition and lifestyle factors influence total and regional bone mineral density in overweight Japanese women...
  51. ncbi request reprint Association of seropositivity for antibody to Chlamydia-specific lipopolysaccharide and coronary artery disease in Japanese men
    K Shimada
    Department of Cardiology, Juntendo University, School of Medicine, Tokyo, Japan
    Jpn Circ J 65:182-7. 2001
    ..This study discovered that IgA antibody to Chlamydia was significantly associated with CAD, especially with MI, in Japanese Men and the findings suggest that chronic infection of Chlamydia may be linked to the pathogenesis of MI...
  52. ncbi request reprint Evaluation and structure-activity relationship of synthesized cyclohexanol derivatives on percutaneous absorption of ketoprofen using artificial neural network
    Y Obata
    Department of Pharmaceutics, Hoshi University, Ebara 2 4 41, Shinagawa, 142 8501, Tokyo, Japan
    Int J Pharm 212:223-31. 2001
    ..The contribution index of logP was approximately 50% in the prediction of Ef, suggesting that lipophilicity among physicochemical properties contributes most of the promoting activity of these compounds...
  53. ncbi request reprint Guanabenz, an antihypertensive centrally acting alpha2-agonist, suppresses morning elevations in aggregation of human platelets
    J Hayashi
    Department of Medicine and Gerontology, School of Medicine, Kyorin University, Tokyo, Japan
    J Cardiovasc Pharmacol 37:89-93. 2001
    ..Thus, in addition to its antihypertensive actions, guanabenz may help to reduce the risk of vascular accidents, which frequently occur in the morning...
  54. ncbi request reprint Otolith and canal integration on single vestibular neurons in cats
    Y Uchino
    Department of Physiology, Tokyo Medical University, 6 1 1 Shinjuku, Shinjuku ku, Tokyo, 160 8402, Japan
    Exp Brain Res 164:271-85. 2005
    ..Some of the convergent neurons that receive both canal and otolith input may contribute to the short-latency pathway of the vestibulocollic reflex. The functional significance of these convergences is discussed...
  55. ncbi request reprint Mapping of rat bilirubin UDP-glucuronosyl-transferase gene (Ugt1a1) to chromosome region 9q35-->q36
    F Nagai
    Kyoritsu College of Pharmacy, Tokyo, Japan
    Cytogenet Cell Genet 69:185-6. 1995
    ..This assignment is the first report on the location of a gene of the rat UGT1 complex using high-resolution banded metaphase chromosomes...
  56. ncbi request reprint Influence of working side contacts on masticatory function for mandibular distal extension removable partial dentures
    S Sueda
    Removable Prosthodontics, Department of Masticatory Function Rehabilitation, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Oral Rehabil 30:301-6. 2003
    ..However, there was no significant difference in the comminuting ability test. These results suggested that working side contacts between artificial teeth and opposite natural teeth influenced mixing ability, but not comminuting ability...
  57. ncbi request reprint Novel 615delC mutation in the CRX gene in a Japanese family with cone-rod dystrophy
    Toshitaka Itabashi
    Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan
    Am J Ophthalmol 138:876-7. 2004
    ..To characterize the clinical features of a Japanese family with cone-rod dystrophy associated with a novel 615delC mutation in the cone-rod homeobox (CRX) gene...
  58. ncbi request reprint Preliminary study of hair form of Japanese head hairs using image analysis
    Hajime Sato
    National Research Institute of Police Science, 6 3 1 Kashiwanoha, Kashiwa, Chiba 277 0882, Japan
    Forensic Sci Int 131:202-8. 2003
    ..The use of an objective measure of hair form will be especially useful for Japanese head hairs since they are generally thought to show very limited variation in morphological features...
  59. ncbi request reprint Screening for mutations in the IMPDH1 gene in Japanese patients with autosomal dominant retinitis pigmentosa
    Yuko Wada
    Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan
    Am J Ophthalmol 140:163-5. 2005
    ....
  60. ncbi request reprint Clinical features of Japanese families with a 402delT or a 555-556delAG mutation in choroideremia gene
    Toshitaka Itabashi
    Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan
    Retina 24:940-5. 2004
    ..To characterize the clinical features of two Japanese families with choroideremia associated with a 402delT and a 555-556delAG mutation in the choroideremia gene (CHM)...
  61. ncbi request reprint Pediatric cardiac surgery without homologous blood transfusion, using a miniaturized bypass system in infants with lower body weight
    Kagami Miyaji
    Department of Thoracic and Cardiovascular Surgery, Kitasato University School of Medicine, Sagamihara, Japan
    J Thorac Cardiovasc Surg 134:284-9. 2007
    ..The priming volume of our system is down to 140 mL for patients weighing less than 7 kg. We can prime the bypass circuits without blood products for patients weighing more than 4 kg...
  62. ncbi request reprint Miniaturized cardiopulmonary bypass system in neonates and small infants
    Kagami Miyaji
    Department of Cardiovascular Surgery, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara, Kanagawa 228 8555, Japan
    Interact Cardiovasc Thorac Surg 7:75-8. 2008
    ..02, P=0.001) most affected the MVT (days). The miniaturized circuits reduced the peri-operative inflammatory response, resulting in reduced postoperative systemic edema, and postoperative mechanical ventilation time...
  63. ncbi request reprint Phylogeny of gamma-polyglutamic acid-producing Bacillus strains isolated from fermented soybean foods manufactured in Asian countries
    Jomkhwan Meerak
    Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Shizuoka, Japan
    J Gen Appl Microbiol 53:315-23. 2007
    ..The results of the present study indicate that PGA-producing strains isolated from local natto in Asian countries and soil in Japan can be divided into two species, B. subtilis and B. amyloliquefaciens...
  64. ncbi request reprint Novel 2336-2337delCT mutation in RP1 gene in a Japanese family with autosomal dominant retinitis pigmentosa
    Miyuki Kawamura
    Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan
    Am J Ophthalmol 137:1137-9. 2004
    ..To determine the frequency and kinds of mutations in the RP1 gene, and to characterize the clinical features of a Japanese family with autosomal dominant retinitis pigmentosa (ADRP) with a novel 2336 to 2337delCT mutation in the RP1 gene...
  65. ncbi request reprint Clinical features of a Japanese family with autosomal dominant retinitis pigmentosa associated with a Thr494Met mutation in the HPRP3 gene
    Yuko Wada
    Department of Ophthalmology, Tohoku University School of Medicine, 1 1, Seiryo machi, Aoba ku, 980 77, Sendai, Japan
    Graefes Arch Clin Exp Ophthalmol 242:956-61. 2004
    ..To determine the clinical features of a Japanese family with autosomal dominant retinitis pigmentosa (ADRP) associated with a Thr494Met mutation in the HPRP3 gene...
  66. ncbi request reprint Alleles responsible for ABO phenotype-genotype discrepancy and alleles in individuals with a weak expression of A or B antigens
    Natsuko Mizuno
    National Research Institute of Police Science, 6 3 1, Kashiwanoha Kashiwa, Chiba 277 0082, Japan
    J Forensic Sci 49:21-8. 2004
    ..Therefore, the existence of such alleles must be given some consideration when predicting phenotype based on genotype...
  67. ncbi request reprint Japanese population database for nine STR loci of the AmpFlSTR Profiler kit
    Kanako Yoshida
    National Research Institute of Police Science, 6 3 1 Kashiwanoha, Kashiwa, 277 0882, Chiba, Japan
    Forensic Sci Int 132:166-7. 2003
    ..Allele frequencies for nine short tandem repeats (STR) loci: D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317 and D7S820 were determined in a Japanese population using the AmpFlSTR Profiler PCR amplification kit (Applied biosystems)...
  68. ncbi request reprint Mutations in the pre-mRNA splicing gene, PRPF31, in Japanese families with autosomal dominant retinitis pigmentosa
    Hajime Sato
    Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
    Am J Ophthalmol 140:537-40. 2005
    ..To describe the clinical and genetic characteristics of three Japanese families with autosomal dominant retinitis pigmentosa (ADRP) associated with mutations in the PRPF31 gene...