Kieko Saito

Summary

Affiliation: University of Shizuoka
Country: Japan

Publications

  1. ncbi request reprint ESR imaging on a solid-tumor-bearing mouse using spin-labeled dextran
    K Saito
    Institute for Environmental Sciences, University of Shizuoka, Yada, Japan
    Biosci Biotechnol Biochem 65:787-94. 2001
  2. ncbi request reprint ESR characterization of a novel spin-trapping agent, 15N-labeled N-tert-butyl-alpha-phenylnitrone, as a nitric oxide donor
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Shizuoka 422 8526, Japan
    Biosci Biotechnol Biochem 66:2189-93. 2002
  3. ncbi request reprint Nitric oxide and effect of a radical scavenger N-tert-butyl-alpha-phenylnitrone on stroke in a rat model
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Shizuoka, Japan
    Pharmacology 73:76-80. 2005
  4. ncbi request reprint Feasibility of simple chitosan sheet as drug delivery carrier
    Kieko Saito
    Institute for Enviromental Sciences, University of Shizuoka, Shizuoka, Japan
    Eur J Pharm Biopharm 64:161-6. 2006
  5. ncbi request reprint Protective effect of spin trap agent, N-tert-butyl-alpha-phenylnitrone on hyperoxia-induced oxidative stress and its potential as a nitric oxide donor
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Japan
    Free Radic Res 36:143-9. 2002
  6. ncbi request reprint Effect of radical scavenger N-tert-butyl-alpha-phenylnitrone on stroke in a rat model using a telemetric system
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Shizuoka, Japan
    J Pharm Pharm Sci 11:25-31. 2008
  7. ncbi request reprint Preventive effects of green tea catechins on spontaneous stroke in rats
    Masahiko Ikeda
    College of Environment and Disaster Research, Fuji Tokoha University, Ohbuchi, Fuji, Shizuoka, Japan
    Med Sci Monit 13:BR40-5. 2007

Detail Information

Publications7

  1. ncbi request reprint ESR imaging on a solid-tumor-bearing mouse using spin-labeled dextran
    K Saito
    Institute for Environmental Sciences, University of Shizuoka, Yada, Japan
    Biosci Biotechnol Biochem 65:787-94. 2001
    ..These results suggest that TEMPO-DX could stay much longer than a low molecular weight spin probe in vivo and concentrate at the tumor. TEMPO-DX may be useful for developing specific ESR imaging agents for tumor...
  2. ncbi request reprint ESR characterization of a novel spin-trapping agent, 15N-labeled N-tert-butyl-alpha-phenylnitrone, as a nitric oxide donor
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Shizuoka 422 8526, Japan
    Biosci Biotechnol Biochem 66:2189-93. 2002
    ..These results suggested that 15N-PBN is a useful molecule, not only as a spin-trapping agent, but also as an NO donor to explore the pharmacological mechanisms of PBN in vivo...
  3. ncbi request reprint Nitric oxide and effect of a radical scavenger N-tert-butyl-alpha-phenylnitrone on stroke in a rat model
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Shizuoka, Japan
    Pharmacology 73:76-80. 2005
    ..These data demonstrate an association between NO and stroke in M-SHRSP. Further, PBN administration results in maintenance of NO levels after stroke in M-SHRSP...
  4. ncbi request reprint Feasibility of simple chitosan sheet as drug delivery carrier
    Kieko Saito
    Institute for Enviromental Sciences, University of Shizuoka, Shizuoka, Japan
    Eur J Pharm Biopharm 64:161-6. 2006
    ..These results suggested that the chitosan sheet prepared in this study might improve therapeutic efficacy in topical lesions as a carrier of sustained-release drugs...
  5. ncbi request reprint Protective effect of spin trap agent, N-tert-butyl-alpha-phenylnitrone on hyperoxia-induced oxidative stress and its potential as a nitric oxide donor
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Japan
    Free Radic Res 36:143-9. 2002
    ..These findings suggested that PBN functions as an NO donor under specific physiological conditions. PBN appears to protect against hyperoxia-induced NO toxicity by anti-inflammatory action rather than by serving as an NO donor...
  6. ncbi request reprint Effect of radical scavenger N-tert-butyl-alpha-phenylnitrone on stroke in a rat model using a telemetric system
    Kieko Saito
    Institute for Environmental Sciences, University of Shizuoka, Shizuoka, Japan
    J Pharm Pharm Sci 11:25-31. 2008
    ..As a result, no significant difference in age of stroke onset was seen between PBN-treated and control rats, but PBN-treated rats displayed prolonged mean life spans. PBN might be effective in prolonging life span...
  7. ncbi request reprint Preventive effects of green tea catechins on spontaneous stroke in rats
    Masahiko Ikeda
    College of Environment and Disaster Research, Fuji Tokoha University, Ohbuchi, Fuji, Shizuoka, Japan
    Med Sci Monit 13:BR40-5. 2007
    ..In this study, we examined whether tea catechin intake decreases the incidence of spontaneous stroke in M-SHRSP...