Y Osada

Summary

Affiliation: University of Occupational and Environmental Health
Country: Japan

Publications

  1. doi request reprint Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, 1 1, Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan Electronic address
    Exp Parasitol 135:388-96. 2013
  2. pmc Origin of a novel protein-coding gene family with similar signal sequence in Schistosoma japonicum
    Evaristus Chibunna Mbanefo
    Department of Immunogenetics, Institute of Tropical Medicine NEKKEN, and Global COE Program, Nagasaki University, 1 12 4 Sakamoto, 852 8523, Nagasaki, Japan
    BMC Genomics 13:260. 2012
  3. pmc Suppressive effect of azithromycin on Plasmodium berghei mosquito stage development and apicoplast replication
    Shoichi Shimizu
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
    Malar J 9:73. 2010
  4. pmc Parasitic helminths: new weapons against immunological disorders
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Japan, Kitakyushu 807 8555, Japan
    J Biomed Biotechnol 2010:743758. 2010
  5. doi request reprint Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
    Int J Parasitol 39:457-64. 2009
  6. ncbi request reprint The antibody responses to adult-worm antigens of Schistosoma haematobium, among infected and resistant individuals from an endemic community in southern Ghana
    Y Osada
    Parasitology Unit, Noguchi Memorial Institute for Medical Research, University of Ghana, PO Box LG581, Legon, Ghana
    Ann Trop Med Parasitol 97:817-26. 2003
  7. ncbi request reprint Establishment of Schistosoma japonicum calpain-specific mouse T cell hybridomas and identification of a T cell epitope that stimulates IFNgamma production
    Yoshio Osada
    Department of Parasitology and Tropical Public Health, The University of Occupational and Environmental Health, Japan, Kitakyushu 807 8555, Japan
    Vaccine 23:2813-9. 2005
  8. ncbi request reprint Mutagenicity evaluation of Schistosoma spp. extracts by the umu-test and V79/HGPRT gene mutation assay
    Yoshio Osada
    Department of Parasitology and Tropical Public Health, The University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Parasitol Int 54:29-34. 2005
  9. pmc Schistosome: its benefit and harm in patients suffering from concomitant diseases
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Kitakyushu 807 8555, Japan
    J Biomed Biotechnol 2011:264173. 2011
  10. ncbi request reprint Infant schistosomiasis in Ghana: a survey in an irrigation community
    K M Bosompem
    Parasitology Unit, Noguchi Memorial Institute for Medical Research, Legon, Ghana
    Trop Med Int Health 9:917-22. 2004

Collaborators

Detail Information

Publications13

  1. doi request reprint Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, 1 1, Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan Electronic address
    Exp Parasitol 135:388-96. 2013
    ..The genetic absence of IL-10 or STAT6 did not abrogate the anti-hyperglycemic effect of Hp. Hp has a suppressive effect on immune mechanism-mediated experimental T1D via Th2 polarization-independent mechanisms. ..
  2. pmc Origin of a novel protein-coding gene family with similar signal sequence in Schistosoma japonicum
    Evaristus Chibunna Mbanefo
    Department of Immunogenetics, Institute of Tropical Medicine NEKKEN, and Global COE Program, Nagasaki University, 1 12 4 Sakamoto, 852 8523, Nagasaki, Japan
    BMC Genomics 13:260. 2012
    ....
  3. pmc Suppressive effect of azithromycin on Plasmodium berghei mosquito stage development and apicoplast replication
    Shoichi Shimizu
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
    Malar J 9:73. 2010
    ..This study evaluated the transmission-blocking effect of AZM using a rodent malaria model...
  4. pmc Parasitic helminths: new weapons against immunological disorders
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Japan, Kitakyushu 807 8555, Japan
    J Biomed Biotechnol 2010:743758. 2010
    ..We also discuss possible mechanisms of helminth-induced suppression according to the recent advances of immunology...
  5. doi request reprint Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
    Int J Parasitol 39:457-64. 2009
    ....
  6. ncbi request reprint The antibody responses to adult-worm antigens of Schistosoma haematobium, among infected and resistant individuals from an endemic community in southern Ghana
    Y Osada
    Parasitology Unit, Noguchi Memorial Institute for Medical Research, University of Ghana, PO Box LG581, Legon, Ghana
    Ann Trop Med Parasitol 97:817-26. 2003
    ..These results indicate that anti-worm IgE and IgG could be used as markers to reflect current infection intensity, and that anti-worm antibodies may not act as protective antibodies in the natural course of urinary schistosomiasis...
  7. ncbi request reprint Establishment of Schistosoma japonicum calpain-specific mouse T cell hybridomas and identification of a T cell epitope that stimulates IFNgamma production
    Yoshio Osada
    Department of Parasitology and Tropical Public Health, The University of Occupational and Environmental Health, Japan, Kitakyushu 807 8555, Japan
    Vaccine 23:2813-9. 2005
    ....
  8. ncbi request reprint Mutagenicity evaluation of Schistosoma spp. extracts by the umu-test and V79/HGPRT gene mutation assay
    Yoshio Osada
    Department of Parasitology and Tropical Public Health, The University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
    Parasitol Int 54:29-34. 2005
    ..Our results suggest that there is very little possibility of immediate gene mutation due to the parasite-derived substances in schistosomiasis-related carcinogenesis...
  9. pmc Schistosome: its benefit and harm in patients suffering from concomitant diseases
    Yoshio Osada
    Department of Immunology and Parasitology, University of Occupational and Environmental Health, Kitakyushu 807 8555, Japan
    J Biomed Biotechnol 2011:264173. 2011
    ..In this paper, we summarize the beneficial and harmful effects of schistosomes. The importance of controlling schistosomiasis is also discussed...
  10. ncbi request reprint Infant schistosomiasis in Ghana: a survey in an irrigation community
    K M Bosompem
    Parasitology Unit, Noguchi Memorial Institute for Medical Research, Legon, Ghana
    Trop Med Int Health 9:917-22. 2004
    ..Fifteen of 71 S. haematobium egg negative individuals tested dipstick positive, giving a dipstick specificity of 78.9% as compared with microscopy as gold standard test. The relative sensitivity of the dipstick was 100%...
  11. ncbi request reprint 2-Cys peroxiredoxins from Schistosoma japonicum: the expression profile and localization in the life cycle
    Takashi Kumagai
    Department of Parasitology and Tropical Public Health, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyusyu 807 8555, Japan
    Mol Biochem Parasitol 149:135-43. 2006
    ....
  12. ncbi request reprint Schistosoma japonicum: localization of calpain in the penetration glands and secretions of cercariae
    Takashi Kumagai
    Department of Parasitology and Tropical Public Health, The University of Occupational and Environmental Health Japan, Kitakyusyu, Japan
    Exp Parasitol 109:53-7. 2005
    ..Calpain-based vaccines could thus possibly induce protective immunity against cercariae and the following early developing stages...
  13. ncbi request reprint Early detection of Schistosoma mansoni infection by touchdown PCR in a mouse model
    Tomoyuki Suzuki
    Department of Parasitology and Tropical Public Health, University of Occupational and Environmental Health, Japan 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu, 807 8555, Japan
    Parasitol Int 55:213-8. 2006
    ..In contrast, S. mansoni DNA was detected in the sera at 2 weeks post-infection. These data suggest that touchdown PCR is a potential tool for the early diagnosis of S. mansoni infection...