Affiliation: University of Tokyo
Okubo K, Miyazoe D, Nishiike Y. A conceptual framework for understanding sexual differentiation of the teleost brain. Gen Comp Endocrinol. 2019;: pubmed publisher
..The consequent sexually dimorphic but reversible steroid sensitivity in response to the adult steroid milieu may enable the teleost brain to maintain lifelong sexual lability and to undergo phenotypic sex reversal. ..
Kikuchi Y, Hosono K, Yamashita J, Kawabata Y, Okubo K. Glucocorticoid receptor exhibits sexually dimorphic expression in the medaka brain. Gen Comp Endocrinol. 2015;223:47-53 pubmed publisher
..These findings suggest that glucocorticoids have a greater influence on physiology and behavior mediated by these neuropeptides in females than in males, which may contribute to sex differences in the brain's response to stress. ..
Okubo K, Takeuchi A, Chaube R, Paul Prasanth B, Kanda S, Oka Y, et al
. Sex differences in aromatase gene expression in the medaka brain. J Neuroendocrinol. 2011;23:412-23 pubmed publisher
..These unique properties of aromatase expression in the brain probably contribute substantially to the less rigid sexual differentiation process, thus ensuring remarkable sexual plasticity in the teleost brain. ..
Maehiro S, Takeuchi A, Yamashita J, Hiraki T, Kawabata Y, Nakasone K, et al
. Sexually dimorphic expression of the sex chromosome-linked genes cntfa and pdlim3a in the medaka brain. Biochem Biophys Res Commun. 2014;445:113-9 pubmed publisher