Research Topics
| T NishiyamaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Publications
Analgesic effects of systemic midazolam: comparison with intrathecal administrationTomoki Nishiyama
Department of Anesthesiology, The Univesity of Tokyo, Japan
Can J Anaesth 53:1004-9. 2006..In the present study, the antinociceptive properties of systemically vs intrathecally administered midazolam were investigated in a rat model of thermal and inflammatory pain...
The median approach to transsacral epidural blockTomoki Nishiyama
Surgical Center, The Institute of Medical Science, Department of Anesthesiology, The University of Tokyo, USA
Anesth Analg 95:1067-70, table of contents. 2002..We found that it is technically feasible in adults and presents an alternative to caudal block for procedures on the rectal, anal, or urethral region...
Effects of combining midazolam and barbiturate on the response to tracheal intubation: changes in autonomic nervous systemTomoki Nishiyama
Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
J Clin Anesth 14:344-8. 2002....
Rapid inhalation induction with 7% sevoflurane combined with intravenous midazolamTomoki Nishiyama
Surgical Center, Department of Anesthesiology, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, 108 8639 Tokyo, Japan
J Clin Anesth 14:290-5. 2002..To identify an improved rapid inhalation induction (RII) technique by investigating hemodynamics and heart rate variability of induction with midazolam and RII with 7% sevoflurane in comparison with RII alone...
Effects of adding midazolam on the postoperative epidural analgesia with two different doses of bupivacaineTomoki Nishiyama
Surgical Center, The Institute of Medical Science, The University of Tokyo, Japan
J Clin Anesth 14:92-7. 2002..To investigate the interaction of midazolam with different doses of bupivacaine, by comparing the analgesic, sedative, and amnesic effects of continuous epidural midazolam with two different doses of bupivacaine...
Hemolysis in stored red blood cell concentrates: modulation by haptoglobin or ulinastatin, a protease inhibitorT Nishiyama
Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
Crit Care Med 29:1979-82. 2001..Haptoglobin binds to free hemoglobin to reduce hemolysis. The purpose of the study was to investigate the effects of ulinastatin on hemolysis in blood preparations in comparison with haptoglobin...
The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of ratsT Nishiyama
Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
Anesth Analg 93:1025-31. 2001..IMPLICATIONS: Spinally-administered midazolam, a benzodiazepine, and clonidine, an alpha2-adrenergic receptor agonist, have significant synergistic effects on thermally-induced acute and formalin-induced inflammatory pain...
Propofol-induced bronchoconstriction: two case reportsT Nishiyama
Surgical Center, The Institute of Medical Science, and Department of AnesthesiologyThe University of Tokyo, Tokyo, Japan
Anesth Analg 93:645-6. 2001..One had severe bronchospasm improved by epinephrine. Propofol should be used with caution in patients with allergic disease...
Synergistic analgesic effects of intrathecal midazolam and NMDA or AMPA receptor antagonists in ratsT Nishiyama
Department of Surgical Center, Institute of Medical Science, University of Tokyo, Japan
Can J Anaesth 48:288-94. 2001..To investigate the interaction of midazolam and N-methyl-D-aspartate (NMDA) receptor or -amino-3-hydroxy-5-methyl isoxazole-4-propionic acid (AMPA) receptor antagonist on the effects of persistent inflammatory nociceptive activation...
The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in ratsT Nishiyama
Department of Anesthesiology, Harbor University of California, Los Angeles Medical Center, Torrance, California, USA
Anesth Analg 92:725-32. 2001....
A traumatic asphyxia in a childT Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Japan
Can J Anaesth 47:1099-102. 2000..We report a case of traumatic asphyxia in a child who recovered without specific treatment, even though chest and abdominal compression was severe...
Continuous nicardipine infusion to control blood pressure after evacuation of acute cerebral hemorrhageT Nishiyama
Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Japan
Can J Anaesth 47:1196-201. 2000....
Do the effects of a protease inhibitor, ulinastatin, on elastase release by blood transfusion depend on interleukin 6?T Nishiyama
Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
Crit Care Med 29:2106-10. 2001..Ulinastatin, a protease inhibitor, inhibits PMNE release by blood transfusion. The purpose of this study was to investigate whether the effects of ulinastatin on PMNE release by blood transfusion come through inhibition of IL-6...
Analgesic interaction between intrathecal midazolam and glutamate receptor antagonists on thermal-induced pain in ratsT Nishiyama
Department of Anesthesiology, Harbor University of California, Los Angeles Medical Center, USA
Anesthesiology 91:531-7. 1999..The purpose of this study was to investigate the spinal analgesic interaction between midazolam, a benzodiazepine-GABA(A) receptor agonist, and two glutamate receptor antagonists on acute thermal nociception...
Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesiaT Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Can J Anaesth 47:693-8. 2000..In contrast, the AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor antagonists have a major role in acute nociception. We investigated the interactions among these three antagonists in acute nociception...
Interaction between intrathecal morphine and glutamate receptor antagonists in formalin testT Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Eur J Pharmacol 395:203-10. 2000..Spinal mu-opioid receptor activation and NMDA or AMPA receptor antagonism showed a synergistic antinociception against tonic pain. These results suggest an important direction in the management of inflammatory pain...
Analgesic effects of intrathecally administered celecoxib, a cyclooxygenase-2 inhibitor, in the tail flick test and the formalin test in ratsT Nishiyama
Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
Acta Anaesthesiol Scand 50:228-33. 2006..The purpose of this study was to examine the analgesic effects of intrathecally administered celecoxib on inflammatory induced pain, thermal-induced pain and hemodynamics...
Interaction between a NMDA receptor antagonist, AP-5 and an AMPA receptor antagonist, YM 872 in antinociception in the spinal cordT Nishiyama
Department of Anesthesiology, The University of Tokyo, Hongo, Bunkyo ku, Tokyo, Japan
Acta Anaesthesiol Scand 52:493-8. 2008..The present study was performed to investigate the interaction between intrathecal AP-5 and YM 872 in antinociception for acute and chronic nociception...
Nicardipine did not activate renin-angiotensin-aldosterone system during isoflurane or sevoflurane anesthesiaT Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Can J Anaesth 47:1249-52. 2000..To investigate the changes of renin-angiotensin-aldosterone system by nicardipine administration during isoflurane or sevoflurane anesthesia...
Is the ARX index a more sensitive indicator of anesthetic depth than the bispectral index during sevoflurane/nitrous oxide anesthesia?T Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Acta Anaesthesiol Scand 48:1028-32. 2004..The purpose of this study was to compare the changes of the A-line ARX index and the bispectral index during sevoflurane - nitrous oxide anesthesia...
Optimal dose of thiamylal in combination with midazolam for induction of anaesthesiaT Nishiyama
Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Japan
Can J Anaesth 43:1134-7. 1996..The optimal dose range of thiamylal, combined with midazolam, in the induction of anaesthesia was evaluated using haemodynamic variables...
Intrathecal edaravone, a free radical scavenger, is effective on inflammatory-induced pain in ratsT Nishiyama
Department of Anaesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
Acta Anaesthesiol Scand 49:147-51. 2005..The purpose of this study was to investigate analgesic effects of intrathecally administered edaravone, a free radical scavenger, on thermal and inflammatory pain...
Haemodynamic and catecholamine changes during rapid sevoflurane induction with tidal volume breathingT Nishiyama
Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Japan
Can J Anaesth 44:1066-70. 1997..v...
The effects of epidural bupivacaine, morphine, and their combination on thermal nociception with different stimulus intensity in ratsT Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Anesth Analg 91:652-6. 2000..IMPLICATIONS: When patients have severe pain even when receiving epidural morphine, adding bupivacaine might be more effective than increasing the dose of epidural morphine...
Free hemoglobin concentrations in patients receiving massive blood transfusion during emergency surgery for traumaT Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Japan
Can J Anaesth 47:881-5. 2000..To determine free hemoglobin concentration in patients who received massive blood transfusion during emergency surgery for trauma with consideration of the storage of the transfused blood...
Optimal length and angle of a new lightwand device (Trachlight)T Nishiyama
Department of Anesthesiology, University of Tokyo, Faculty of Medicine, Japan
J Clin Anesth 11:332-5. 1999..To investigate the effects of angle and length of the Trachlight lightwand and the effect of obesity on transillumination of the neck and difficulty of intubation...
Molecular phylogenetic analysis among bryophytes and tracheophytes based on combined data of plastid coded genes and the 18S rRNA geneT Nishiyama
Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan
Mol Biol Evol 16:1027-36. 1999..Total-evidence evaluation of rRNA data and plastid protein-coding genes by TOTALML had an almost identical result...
Changes in the auditory evoked potentials index by induction doses of four different intravenous anestheticsT Nishiyama
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
Acta Anaesthesiol Scand 49:1326-9. 2005..The present study was performed to compare the changes in AAI caused by induction doses of thiopental, propofol, midazolam and ketamine...
Novel antagonists for proteinase-activated receptor 2: inhibition of cellular and vascular responses in vitro and in vivoT Kanke
Tokyo New Drug Research Laboratories, Kowa Company Limited, Noguchicho, Higashimurayama, Tokyo, Japan
Br J Pharmacol 158:361-71. 2009..Here, we identify a number of novel peptide-mimetic PAR(2) antagonists and demonstrate inhibitory effects on PAR(2)-mediated intracellular signalling pathways and vascular responses...
[Anesthesia for emergency surgery in a patient with Shy-Drager syndrome]H Hashimoto
Department of Anesthesiology, University of Tokyo, Faculty of Medicine, Tokyo 113-8655
Masui 50:40-1. 2001..He was extubated on the first postoperative day without any complications. The effects of vecuronium, norepinephrine, and dopamine might be changed in the patient with Shy-Drager syndrome...
Amelioration of lacrimal gland inflammation by oral administration of K-13182 in Sjögren's syndrome model miceT Nishiyama
Department of Pathology, Tsurumi University School of Dental Medicine, Yokohama, Japan Sjögren s Syndrome Project, Shinanomachi Research Park, Keio University, Tokyo, Japan
Clin Exp Immunol 149:586-95. 2007..These data reveal that VCAM-1 is a promising target molecule for the treatment of autoimmune diseases as a therapeutic strategy and that K-13182 has the potential as a new anti-inflammatory drug for SS...
[Useful tools for prone position: ProneView and OPTI-GARD]T Nishiyama
Surgical Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639
Masui 50:1357-9. 2001..In addition, we can check the position of the face easily by mirror. Therefore, the ProneView and the OPTI-GARD must be useful to decrease injuries to eyes, nose, lips, ears, and facial nerve, and neck pain in prone position...
Comparison of the transcutaneous oxygen and carbon dioxide tension in different electrode locations during general anaesthesiaT Nishiyama
The University of Tokyo, Faculty of Medicine, Department of Anesthesiology, Tokyo, Japan
Eur J Anaesthesiol 23:1049-54. 2006..The best place for the electrode of transcutaneous measurement of oxygen tension (tcPO2) and carbon dioxide tension (tcPCO2) during general anaesthesia was investigated in three different locations...
Effects of a 5-HT2A receptor antagonist, sarpogrelate on thermal or inflammatory painTomoki Nishiyama
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Eur J Pharmacol 516:18-22. 2005..In conclusion, sarpogrelate might be analgesic on inflammatory induced acute and facilitated pain by intrathecal or systemic administration. However, only systemic administration could be effective on thermal induced acute pain...
Intrathecal propofol has analgesic effects on inflammation-induced pain in ratsTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
Can J Anaesth 51:899-904. 2004..In this study, we examined the effects of intrathecal propofol on acute thermally- or inflammation-induced pain in rats...
Sedation guidelines for midazolam infusion during combined spinal and epidural anesthesiaTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
J Clin Anesth 16:568-72. 2004..To investigate the adequate infusion dose regimen of midazolam to induce sedation with the Ramsay score 4 with rapid onset during combined spinal and epidural anesthesia..
Dose-finding study of intravenous midazolam for sedation and amnesia during spinal anesthesia in patients premedicated with intramuscular midazolamTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
J Anesth 18:257-61. 2004..06 mg.kg(-1) as a premedication, intravenous midazolam 0.02 mg.kg(-1) might be effective and safe...
Spinal cord blood flow change by intravenous midazolam during isoflurane anesthesiaTomoki Nishiyama
Department of Anesthesiology, University of Tokyo, Japan
Anesth Analg 101:242-5, table of contents. 2005..In contrast, a larger dose of midazolam (4 mg/kg) did not change spinal cord blood flow but substantially decreased arterial blood pressure during isoflurane anesthesia...
Hemodynamic and catecholamine response to a rapid increase in isoflurane or sevoflurane concentration during a maintenance phase of anesthesia in humansTomoki Nishiyama
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan
J Anesth 19:213-7. 2005..CONCLUSION: During surgery a sudden increase in isoflurane concentration induced larger changes in hemodynamics and sympathetic nerve activity than sevoflurane...
Stress hormone changes in general anesthesia of long duration: isoflurane-nitrous oxide vs sevoflurane-nitrous oxide anesthesiaTomoki Nishiyama
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 113 8655 Tokyo, Japan
J Clin Anesth 17:586-91. 2005..We investigated perioperative changes of stress hormone in these two anesthetic methods with duration of more than 10 hours...
Comparison between neurotropin and mepivacaine for stellate ganglion injectionTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
J Anesth 20:240-2. 2006..In conclusion, the SG injection of neurotropin decreased the VAS score in postherpetic neuralgia to the same extent as mepivacaine. The incidence of Horner's sign was significantly lower with neurotropin than with mepivacaine...
Efficacy of a heat and moisture exchanger in inhalation anesthesia at two different flow ratesKoichi Yamashita
Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku, Kochi, 783 8505, Japan
J Anesth 21:55-8. 2007..During general anesthesia with a total flow of 2 lxmin(-1) in 2 h, HME might not be necessary, while with a total flow of 4 lxmin(-1), HME could be useful to maintain inspired gas humidity...
Inhibitory effects of intravenous anesthetics on mast cell functionTakahiro Fujimoto
Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, Japan
Anesth Analg 101:1054-9, table of contents. 2005..Ketamine, midazolam, and propofol had a dose-dependent inhibitory effect on mast cell exocytosis. The impairment of mast cell function by IV anesthetics may influence the defense against infection...
How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofenTomoki Nishiyama
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
J Anesth 19:273-6. 2005..CONCLUSIONS: Flurbiprofen 50 mg i.v. just before propofol injection completely abolished propofol injection pain. When it was administered 1 min before propofol injection it was less effective...
[A case of giant thyroid tumor with tracheal stenosis]Ju Mizuno
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8665
Masui 53:682-6. 2004..Intubation under conscious sedation with midazolam and fentanyl is useful for a patient with a giant thyroid tumor and tracheal stenosis...
Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced painTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Anesth Analg 96:1386-91, table of contents. 2003..IMPLICATIONS: In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats...
[Sedation with intravenous midazolam during upper gastrointestinal endoscopy--changes in hemodynamics, oxygen saturation and memory]Ju Mizuno
Pain Relief Center, Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113-8655
Masui 52:976-80. 2003..CONCLUSIONS: Sedation with intravenous midazolam during upper gastrointestinal endoscopy is useful to control the cardiovascular responses, and to obtain amnesia. However, a decrease in SpO2 should be watched carefully...
Comparison of hemodynamic and anesthetic effects of hyperbaric bupivacaine and tetracaine in spinal anesthesiaTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
J Anesth 17:218-22. 2003..46 in the Tetracaine group. CONCLUSION: In spinal anesthesia, hyperbaric tetracaine in 10% glucose induced a faster and higher spread of anesthesia than hyperbaric bupivacaine in 7.27% glucose without any differences in hemodynamics...
A comparison of liver function after hepatectomy in cirrhotic patients between sevoflurane and isoflurane in anesthesia with nitrous oxide and epidural blockTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
Anesth Analg 98:990-3, table of contents. 2004..However, the increases were small, and there was no clinical liver damage...
Serum and cerebrospinal fluid concentrations of midazolam after epidural administration in dogsTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
Anesth Analg 96:159-62, table of contents. 2003..Epidurally administered midazolam enters the cerebrospinal fluid, but concentrations are only 3% of those in the systemic circulation...
Intrathecal clonidine and bupivacaine have synergistic analgesia for acute thermally or inflammatory-induced pain in ratsTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
Anesth Analg 98:1056-61, table of contents. 2004..The analgesia produced by the combination of these two drugs was synergistic in both acute thermal and inflammatory induced pain, with a decrease in behavioral side effects...
A comparison of the clinical usefulness of three different electroencephalogram monitors: Bispectral Index, processed electroencephalogram, and Alaris auditory evoked potentialsTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
Anesth Analg 98:1341-5, table of contents. 2004....
[A case of ectopic pheochromocytoma of pulmonary origin]Takahiro Fujimoto
Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655
Masui 53:537-9. 2004..A case of ectopic pheochromocytoma of pulmonary origin was managed with midazolam, propofol, fentanyl and continuous epidural block. Diltiazem, nicardipine and norepinephrine were administered to control blood pressure...
The A-line ARX index may be a more sensitive detector of arousal than the bispectral index during propofol-fentanyl-nitrous oxide anesthesia: a preliminary investigationTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
Can J Anaesth 51:539-44. 2004..To compare changes in the A-line ARX index (AAI) by the Alaris AEP monitor(TM) with those of the bispectral index (BIS) during propofol-fentanyl-nitrous oxide anesthesia...
Spinal neurotoxicity and tolerance after repeated intrathecal administration of YM 872, an AMPA receptor antagonist, in ratsTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Japan
J Anesth 18:113-7. 2004..No changes were observed in the spinal cord in either group. CONCLUSION: Administration of YM 872 (1 micro g) once a day for 30 days did not induce any tolerance and caused no histological changes in the spinal cord...
[Anesthetic management of a morbidly obese patient with mental retardation]Masako Seyama
Department of Anesthesiology, The University of Tokyo, Tokyo 113-8655
Masui 55:1225-7. 2006..We successfully used ultrasound sonography to identify spinous process and could insert an epidural catheter at the right place...
Accidental overdose of midazolam as intramuscular premedicationTomoki Nishiyama
Surgical Center, Institute of Medical Science, and Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
J Clin Anesth 14:543-5. 2002..However, the situations suggest that we should carefully check the dosage and review the correct procedures, even when using a drug that is considered to be familiar with most practitioners...
[A new heat and moisture exchanger, Trach-Vent Plus, for patients with spontaneous respiration]Tomoki Nishiyama
Surgical Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639
Masui 52:417-9. 2003..This new heat and moisture exchanger, Trach-Vent Plus is useful to administer oxygen to intubated patients breathing spontaneously, especially with tracheostomy...
Effects of vasodilation on cardiac output measured by PulseCOKoichi Yamashita
Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku Shi, Kochi, 783 8505, Japan
J Clin Monit Comput 21:335-9. 2007..during cardiac surgery has been reported. In the present study, we investigated the effects of vasodilation by prostaglandin E1 (PGE1) on the relation between cardiac output measured by PulseCO and that by thermodilution...
[Usefulness of a new nasal cannula with an end-tidal carbon dioxide measuring port]Tomoki Nishiyama
Surgical Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639
Masui 52:424-6. 2003..CONCLUSION: A new cannula with EtCO2 port is useful to oxygenate and measure EtCO2 simultaneously except when patients snore or move...
Effects of quazepam as a preoperative night hypnotic: comparison with brotizolamTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
J Anesth 21:7-12. 2007..The purpose of this study was to evaluate the effects of quazepam, a long-acting hypnotic, as a preoperative night medication in comparison with brotizolam, a shortacting hypnotic...
Electrostatic field can preserve red blood cells in stored blood preparationsTomoki Nishiyama
Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
J Anesth 21:42-6. 2007..We hypothesized that the storage of CRCs under an electrostatic field could keep red blood cells in better condition than conventional storage...
[Bronchospasm during upper gastrointestinal endoscopy under sedation]Ju Mizuno
Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113-8665
Masui 52:170-3. 2003..The insertion of upper gastrointestinal endoscope might have induced bronchospasm stimulating distal esophageal afferent vagal reflex partly by regurgitation of gastric acid under sedation...
Propofol infusion for sedation during spinal anesthesiaTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, 7 3 1, Hongo, Tokyo 113 8655, Japan
J Anesth 21:265-9. 2007..The dose and time course of propofol infusion required to induce rapid sedation without oversedation during spinal anesthesia were investigated...
Changes in percutaneous oxygen tension induced by spinal anesthesiaTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, 7 3 1 Hongo, Tokyo 113 8655, Japan
J Anesth 21:317-9. 2007..The purpose of this study was to determine whether changes in percutaneous oxygen tension (tcPO(2)) were suitable for checking the level of spinal anesthesia...
Antithrombin can modulate coagulation, cytokine production, and expression of adhesion molecules in abdominal aortic aneurysm repair surgeryTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
Anesth Analg 102:1007-11. 2006..In conclusion, antithrombin could decrease hypercoagulation and inflammatory activation during abdominal aortic aneurysm surgery, which may decrease adverse events...
[Cardiac arrest during bilateral inguinal herniorrhaphy under epidural anesthesia]Kazuhiro Nagao
Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Nankoku 783-8505
Masui 53:1404-6. 2004..Vagal reflex induced by bilateral inguinal herniorrhaphy might cause cardiac arrest. We should be careful for vagal reflex during bilateral herniorrhaphy...
Blood flow velocity of the femoral vein with foot exercise compared to pneumatic foot compressionKoichi Yamashita
Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kochi 783 8505, Japan
J Clin Anesth 17:102-5. 2005..To compare the effects of foot exercise with an intermittent pneumatic foot compression (IPC) device on blood flow velocity of the femoral veins...
Cardiac output by PulseCO is not interchangeable with thermodilution in patients undergoing OPCABKoichi Yamashita
Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku Shi, Kochi, 783 8505, Japan
Can J Anaesth 52:530-4. 2005..To investigate the reliability of cardiac output assessed by arterial pressure waveform (PulseCO) in comparison with bolus thermodilution measurements in patients undergoing off-pump coronary artery bypass grafting (OPCAB)...
[Does common cold increase perioperative respiratory complications in adults?]Tomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo
Masui 54:643-7. 2005..We investigated whether perioperative respiratory complications increase in adults with common cold symptom...
Comparison of the intracuff pressures of three different tracheostomy tubesTomoki Nishiyama
Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
J Anesth 19:260-2. 2005..Based on these results, the MERA sofit CLEAR was found to maintain most safely the lowest intracuff pressure to seal the trachea among the three tracheostomy tubes tested...
[General anesthesia for a patient with Noonan's syndrome and long-term antidepressant therapy]Shinji Nakamura
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo 113-8655
Masui 54:901-3. 2005..This patient presented a problem of difficult intubation as Noonan's syndrome and had a history of a long-term use of antidepressant, which might induce sympathomimetic resistant hypotension...
[A case report of the laryngeal edema and peripheral cyanosis after extubation of the tracheal tube]Keiichi Itatani
Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113-8655
Masui 52:897-9. 2003..The hemodynamic instability during surgery and cyanosis after extubation might have come from changes of the vascular resistance by sepsis...
Doxapram produces a dose-dependent reduction in the shivering threshold in rabbitsKatsumi Okuyama
Department of Anesthesia, University of Yamanashi, Faculty of Medicine, Tamaho, Yamanashi, Japan
Anesth Analg 97:759-62. 2003..50 mg x kg(-1) x h(-1) shivered at 33.7 degrees +/- 0.6 degrees C. All the shivering thresholds significantly (P < 0.001) differed from one another. The magnitude of this inhibition, if similar in humans, would be clinically important...
[General anesthesia for diaphragmatic herniorrhaphy in a patient with myasthenia gravis and severe gibbus]Shinji Nakamura
Department of Anesthesiology, The University of Tokyo, Faculty of Medicine
Masui 54:1371-2. 2005..Thus, we used sevoflurane and epidural block. We successfully anesthetized a patient for diaphragmatic herniorrhaphy complicated with myasthenia gravis and gibbus by sevoflurane and epidural block...
Spinally mediated analgesia and receptor binding affinity of epibatidine analogsTomoki Nishiyama
Department of Anesthesiology, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Eur J Pharmacol 470:27-31. 2003..In summary, the two epibatidine analogs have higher potency ratio of spinally mediated analgesia/side effects than epibatidine...
Core temperature monitoring with new ventilatory devicesTakashi Matsukawa
Department of Anesthesia, University of Yamanashi, Faculty of Medicine, Japan
Anesth Analg 96:1688-91, table of contents. 2003..IMPLICATIONS: Temperatures measured on airway devices correlated well with independent measurements of core body temperature. Thus, body temperature measured on the cuffs of airway devices is sufficiently accurate for routine use...
[High dose L-dopa infusion during general anesthesia for gastrectomy in a patient with parkinsonism]Tetsuya Horai
Department of Anesthesiology, University of Tokyo, Tokyo 113-8655
Masui 51:42-5. 2002..However, he developed no complications, which suggests a wide safety range of levodopa. In conclusion, high dose levodopa infusion was effective in controlling the symptoms of Parkinsonism during general anesthesia...
