T Nishiyama

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi Analgesic effects of systemic midazolam: comparison with intrathecal administration
    Tomoki Nishiyama
    Department of Anesthesiology, The Univesity of Tokyo, Japan
    Can J Anaesth 53:1004-9. 2006
  2. ncbi The median approach to transsacral epidural block
    Tomoki Nishiyama
    Surgical Center, The Institute of Medical Science, Department of Anesthesiology, The University of Tokyo, USA
    Anesth Analg 95:1067-70, table of contents. 2002
  3. ncbi Effects of combining midazolam and barbiturate on the response to tracheal intubation: changes in autonomic nervous system
    Tomoki Nishiyama
    Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    J Clin Anesth 14:344-8. 2002
  4. ncbi Rapid inhalation induction with 7% sevoflurane combined with intravenous midazolam
    Tomoki Nishiyama
    Surgical Center, Department of Anesthesiology, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, 108 8639 Tokyo, Japan
    J Clin Anesth 14:290-5. 2002
  5. ncbi Effects of adding midazolam on the postoperative epidural analgesia with two different doses of bupivacaine
    Tomoki Nishiyama
    Surgical Center, The Institute of Medical Science, The University of Tokyo, Japan
    J Clin Anesth 14:92-7. 2002
  6. ncbi Hemolysis in stored red blood cell concentrates: modulation by haptoglobin or ulinastatin, a protease inhibitor
    T Nishiyama
    Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Crit Care Med 29:1979-82. 2001
  7. ncbi The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats
    T Nishiyama
    Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Anesth Analg 93:1025-31. 2001
  8. ncbi Propofol-induced bronchoconstriction: two case reports
    T Nishiyama
    Surgical Center, The Institute of Medical Science, and Department of AnesthesiologyThe University of Tokyo, Tokyo, Japan
    Anesth Analg 93:645-6. 2001
  9. ncbi Synergistic analgesic effects of intrathecal midazolam and NMDA or AMPA receptor antagonists in rats
    T Nishiyama
    Department of Surgical Center, Institute of Medical Science, University of Tokyo, Japan
    Can J Anaesth 48:288-94. 2001
  10. ncbi The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats
    T Nishiyama
    Department of Anesthesiology, Harbor University of California, Los Angeles Medical Center, Torrance, California, USA
    Anesth Analg 92:725-32. 2001

Collaborators

Detail Information

Publications78

  1. ncbi Analgesic effects of systemic midazolam: comparison with intrathecal administration
    Tomoki Nishiyama
    Department of Anesthesiology, The Univesity of Tokyo, Japan
    Can J Anaesth 53:1004-9. 2006
    ..In the present study, the antinociceptive properties of systemically vs intrathecally administered midazolam were investigated in a rat model of thermal and inflammatory pain...
  2. ncbi The median approach to transsacral epidural block
    Tomoki Nishiyama
    Surgical Center, The Institute of Medical Science, Department of Anesthesiology, The University of Tokyo, USA
    Anesth Analg 95:1067-70, table of contents. 2002
    ..No side effects were observed. We conclude that the median transsacral epidural approach is technically feasible in adults and presents an alternative to caudal block...
  3. ncbi Effects of combining midazolam and barbiturate on the response to tracheal intubation: changes in autonomic nervous system
    Tomoki Nishiyama
    Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    J Clin Anesth 14:344-8. 2002
    ....
  4. ncbi Rapid inhalation induction with 7% sevoflurane combined with intravenous midazolam
    Tomoki Nishiyama
    Surgical Center, Department of Anesthesiology, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku, 108 8639 Tokyo, Japan
    J Clin Anesth 14:290-5. 2002
    ..To identify an improved rapid inhalation induction (RII) technique by investigating hemodynamics and heart rate variability of induction with midazolam and RII with 7% sevoflurane in comparison with RII alone...
  5. ncbi Effects of adding midazolam on the postoperative epidural analgesia with two different doses of bupivacaine
    Tomoki Nishiyama
    Surgical Center, The Institute of Medical Science, The University of Tokyo, Japan
    J Clin Anesth 14:92-7. 2002
    ..To investigate the interaction of midazolam with different doses of bupivacaine, by comparing the analgesic, sedative, and amnesic effects of continuous epidural midazolam with two different doses of bupivacaine...
  6. ncbi Hemolysis in stored red blood cell concentrates: modulation by haptoglobin or ulinastatin, a protease inhibitor
    T Nishiyama
    Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Crit Care Med 29:1979-82. 2001
    ..Haptoglobin binds to free hemoglobin to reduce hemolysis. The purpose of the study was to investigate the effects of ulinastatin on hemolysis in blood preparations in comparison with haptoglobin...
  7. ncbi The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats
    T Nishiyama
    Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Anesth Analg 93:1025-31. 2001
    ..Side effects did not increase by using the combination. These results suggest a favorable combination of intrathecal midazolam and clonidine in the management of acute and inflammatory pain after proper neurotoxicologic studies...
  8. ncbi Propofol-induced bronchoconstriction: two case reports
    T Nishiyama
    Surgical Center, The Institute of Medical Science, and Department of AnesthesiologyThe University of Tokyo, Tokyo, Japan
    Anesth Analg 93:645-6. 2001
    ..Bronchoconstriction was induced by anesthetic induction with propofol in two patients with allergic diseases. One had severe bronchospasm improved by epinephrine. Propofol should be used with caution in patients with allergic disease...
  9. ncbi Synergistic analgesic effects of intrathecal midazolam and NMDA or AMPA receptor antagonists in rats
    T Nishiyama
    Department of Surgical Center, Institute of Medical Science, University of Tokyo, Japan
    Can J Anaesth 48:288-94. 2001
    ..To investigate the interaction of midazolam and N-methyl-D-aspartate (NMDA) receptor or -amino-3-hydroxy-5-methyl isoxazole-4-propionic acid (AMPA) receptor antagonist on the effects of persistent inflammatory nociceptive activation...
  10. ncbi The analgesic interaction between intrathecal clonidine and glutamate receptor antagonists on thermal and formalin-induced pain in rats
    T Nishiyama
    Department of Anesthesiology, Harbor University of California, Los Angeles Medical Center, Torrance, California, USA
    Anesth Analg 92:725-32. 2001
    ..In conclusion, spinally administered clonidine and AP-5 or YM872 exhibited potent synergistic analgesia on acute thermal and formalin-induced nociception with decreased side effects in rats...
  11. ncbi A traumatic asphyxia in a child
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Japan
    Can J Anaesth 47:1099-102. 2000
    ..We report a case of traumatic asphyxia in a child who recovered without specific treatment, even though chest and abdominal compression was severe...
  12. ncbi Continuous nicardipine infusion to control blood pressure after evacuation of acute cerebral hemorrhage
    T Nishiyama
    Department of Surgical Center, The Institute of Medical Science, The University of Tokyo, Japan
    Can J Anaesth 47:1196-201. 2000
    ....
  13. ncbi Do the effects of a protease inhibitor, ulinastatin, on elastase release by blood transfusion depend on interleukin 6?
    T Nishiyama
    Surgical Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
    Crit Care Med 29:2106-10. 2001
    ..Ulinastatin, a protease inhibitor, inhibits PMNE release by blood transfusion. The purpose of this study was to investigate whether the effects of ulinastatin on PMNE release by blood transfusion come through inhibition of IL-6...
  14. ncbi Analgesic interaction between intrathecal midazolam and glutamate receptor antagonists on thermal-induced pain in rats
    T Nishiyama
    Department of Anesthesiology, Harbor University of California, Los Angeles Medical Center, USA
    Anesthesiology 91:531-7. 1999
    ..The purpose of this study was to investigate the spinal analgesic interaction between midazolam, a benzodiazepine-GABA(A) receptor agonist, and two glutamate receptor antagonists on acute thermal nociception...
  15. ncbi Interaction among NMDA receptor-, NMDA glycine site- and AMPA receptor antagonists in spinally mediated analgesia
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Can J Anaesth 47:693-8. 2000
    ..In contrast, the AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor antagonists have a major role in acute nociception. We investigated the interactions among these three antagonists in acute nociception...
  16. ncbi Interaction between intrathecal morphine and glutamate receptor antagonists in formalin test
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Eur J Pharmacol 395:203-10. 2000
    ..Spinal mu-opioid receptor activation and NMDA or AMPA receptor antagonism showed a synergistic antinociception against tonic pain. These results suggest an important direction in the management of inflammatory pain...
  17. ncbi Analgesic effects of intrathecally administered celecoxib, a cyclooxygenase-2 inhibitor, in the tail flick test and the formalin test in rats
    T Nishiyama
    Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Acta Anaesthesiol Scand 50:228-33. 2006
    ..The purpose of this study was to examine the analgesic effects of intrathecally administered celecoxib on inflammatory induced pain, thermal-induced pain and hemodynamics...
  18. doi Interaction between a NMDA receptor antagonist, AP-5 and an AMPA receptor antagonist, YM 872 in antinociception in the spinal cord
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Hongo, Bunkyo ku, Tokyo, Japan
    Acta Anaesthesiol Scand 52:493-8. 2008
    ..The present study was performed to investigate the interaction between intrathecal AP-5 and YM 872 in antinociception for acute and chronic nociception...
  19. ncbi Nicardipine did not activate renin-angiotensin-aldosterone system during isoflurane or sevoflurane anesthesia
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Can J Anaesth 47:1249-52. 2000
    ..To investigate the changes of renin-angiotensin-aldosterone system by nicardipine administration during isoflurane or sevoflurane anesthesia...
  20. ncbi Is the ARX index a more sensitive indicator of anesthetic depth than the bispectral index during sevoflurane/nitrous oxide anesthesia?
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Acta Anaesthesiol Scand 48:1028-32. 2004
    ..The purpose of this study was to compare the changes of the A-line ARX index and the bispectral index during sevoflurane - nitrous oxide anesthesia...
  21. ncbi Optimal dose of thiamylal in combination with midazolam for induction of anaesthesia
    T Nishiyama
    Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Japan
    Can J Anaesth 43:1134-7. 1996
    ..The optimal dose range of thiamylal, combined with midazolam, in the induction of anaesthesia was evaluated using haemodynamic variables...
  22. ncbi Intrathecal edaravone, a free radical scavenger, is effective on inflammatory-induced pain in rats
    T Nishiyama
    Department of Anaesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Acta Anaesthesiol Scand 49:147-51. 2005
    ..The purpose of this study was to investigate analgesic effects of intrathecally administered edaravone, a free radical scavenger, on thermal and inflammatory pain...
  23. ncbi Haemodynamic and catecholamine changes during rapid sevoflurane induction with tidal volume breathing
    T Nishiyama
    Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Japan
    Can J Anaesth 44:1066-70. 1997
    ..v...
  24. ncbi The effects of epidural bupivacaine, morphine, and their combination on thermal nociception with different stimulus intensity in rats
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Anesth Analg 91:652-6. 2000
    ..Therefore, adding bupivacaine might be more effective than increasing the dose of epidural morphine for intense nociception...
  25. ncbi Free hemoglobin concentrations in patients receiving massive blood transfusion during emergency surgery for trauma
    T Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Japan
    Can J Anaesth 47:881-5. 2000
    ..To determine free hemoglobin concentration in patients who received massive blood transfusion during emergency surgery for trauma with consideration of the storage of the transfused blood...
  26. ncbi Optimal length and angle of a new lightwand device (Trachlight)
    T Nishiyama
    Department of Anesthesiology, University of Tokyo, Faculty of Medicine, Japan
    J Clin Anesth 11:332-5. 1999
    ..To investigate the effects of angle and length of the Trachlight lightwand and the effect of obesity on transillumination of the neck and difficulty of intubation...
  27. ncbi Molecular phylogenetic analysis among bryophytes and tracheophytes based on combined data of plastid coded genes and the 18S rRNA gene
    T Nishiyama
    Department of Biological Sciences, Graduate School of Science, University of Tokyo, Japan
    Mol Biol Evol 16:1027-36. 1999
    ..Total-evidence evaluation of rRNA data and plastid protein-coding genes by TOTALML had an almost identical result...
  28. ncbi Changes in the auditory evoked potentials index by induction doses of four different intravenous anesthetics
    T Nishiyama
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Acta Anaesthesiol Scand 49:1326-9. 2005
    ..The present study was performed to compare the changes in AAI caused by induction doses of thiopental, propofol, midazolam and ketamine...
  29. pmc Novel antagonists for proteinase-activated receptor 2: inhibition of cellular and vascular responses in vitro and in vivo
    T Kanke
    Tokyo New Drug Research Laboratories, Kowa Company Limited, Noguchicho, Higashimurayama, Tokyo, Japan
    Br J Pharmacol 158:361-71. 2009
    ..Here, we identify a number of novel peptide-mimetic PAR(2) antagonists and demonstrate inhibitory effects on PAR(2)-mediated intracellular signalling pathways and vascular responses...
  30. ncbi [Anesthesia for emergency surgery in a patient with Shy-Drager syndrome]
    H Hashimoto
    Department of Anesthesiology, University of Tokyo, Faculty of Medicine, Tokyo 113-8655
    Masui 50:40-1. 2001
    ..He was extubated on the first postoperative day without any complications. The effects of vecuronium, norepinephrine, and dopamine might be changed in the patient with Shy-Drager syndrome...
  31. pmc Amelioration of lacrimal gland inflammation by oral administration of K-13182 in Sjögren's syndrome model mice
    T Nishiyama
    Department of Pathology, Tsurumi University School of Dental Medicine, Yokohama, Japan Sjögren s Syndrome Project, Shinanomachi Research Park, Keio University, Tokyo, Japan
    Clin Exp Immunol 149:586-95. 2007
    ..These data reveal that VCAM-1 is a promising target molecule for the treatment of autoimmune diseases as a therapeutic strategy and that K-13182 has the potential as a new anti-inflammatory drug for SS...
  32. ncbi [Useful tools for prone position: ProneView and OPTI-GARD]
    T Nishiyama
    Surgical Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639
    Masui 50:1357-9. 2001
    ..In addition, we can check the position of the face easily by mirror. Therefore, the ProneView and the OPTI-GARD must be useful to decrease injuries to eyes, nose, lips, ears, and facial nerve, and neck pain in prone position...
  33. ncbi Comparison of the transcutaneous oxygen and carbon dioxide tension in different electrode locations during general anaesthesia
    T Nishiyama
    The University of Tokyo, Faculty of Medicine, Department of Anesthesiology, Tokyo, Japan
    Eur J Anaesthesiol 23:1049-54. 2006
    ..The best place for the electrode of transcutaneous measurement of oxygen tension (tcPO2) and carbon dioxide tension (tcPCO2) during general anaesthesia was investigated in three different locations...
  34. ncbi Effects of a 5-HT2A receptor antagonist, sarpogrelate on thermal or inflammatory pain
    Tomoki Nishiyama
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Eur J Pharmacol 516:18-22. 2005
    ..In conclusion, sarpogrelate might be analgesic on inflammatory induced acute and facilitated pain by intrathecal or systemic administration. However, only systemic administration could be effective on thermal induced acute pain...
  35. ncbi Intrathecal propofol has analgesic effects on inflammation-induced pain in rats
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
    Can J Anaesth 51:899-904. 2004
    ..In this study, we examined the effects of intrathecal propofol on acute thermally- or inflammation-induced pain in rats...
  36. ncbi Sedation guidelines for midazolam infusion during combined spinal and epidural anesthesia
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
    J Clin Anesth 16:568-72. 2004
    ..To investigate the adequate infusion dose regimen of midazolam to induce sedation with the Ramsay score 4 with rapid onset during combined spinal and epidural anesthesia..
  37. ncbi Dose-finding study of intravenous midazolam for sedation and amnesia during spinal anesthesia in patients premedicated with intramuscular midazolam
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
    J Anesth 18:257-61. 2004
    ..We investigated the effective and safe dose of intravenous midazolam for sedation and amnesia during spinal anesthesia in patients premedicated with intramuscular midazolam...
  38. ncbi Spinal cord blood flow change by intravenous midazolam during isoflurane anesthesia
    Tomoki Nishiyama
    Department of Anesthesiology, University of Tokyo, Japan
    Anesth Analg 101:242-5, table of contents. 2005
    ..In contrast, a larger dose of midazolam (4 mg/kg) did not change spinal cord blood flow but substantially decreased arterial blood pressure during isoflurane anesthesia...
  39. ncbi Hemodynamic and catecholamine response to a rapid increase in isoflurane or sevoflurane concentration during a maintenance phase of anesthesia in humans
    Tomoki Nishiyama
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    J Anesth 19:213-7. 2005
    ..The purpose of this study was to compare hemodynamic and catecholamine changes due to a sudden increase in inhalation anesthetic concentrations (isoflurane and sevoflurane) during surgery...
  40. ncbi Stress hormone changes in general anesthesia of long duration: isoflurane-nitrous oxide vs sevoflurane-nitrous oxide anesthesia
    Tomoki Nishiyama
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 113 8655 Tokyo, Japan
    J Clin Anesth 17:586-91. 2005
    ..We investigated perioperative changes of stress hormone in these two anesthetic methods with duration of more than 10 hours...
  41. ncbi Comparison between neurotropin and mepivacaine for stellate ganglion injection
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
    J Anesth 20:240-2. 2006
    ..In conclusion, the SG injection of neurotropin decreased the VAS score in postherpetic neuralgia to the same extent as mepivacaine. The incidence of Horner's sign was significantly lower with neurotropin than with mepivacaine...
  42. ncbi Efficacy of a heat and moisture exchanger in inhalation anesthesia at two different flow rates
    Koichi Yamashita
    Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku, Kochi, 783 8505, Japan
    J Anesth 21:55-8. 2007
    ..During general anesthesia with a total flow of 2 lxmin(-1) in 2 h, HME might not be necessary, while with a total flow of 4 lxmin(-1), HME could be useful to maintain inspired gas humidity...
  43. ncbi Inhibitory effects of intravenous anesthetics on mast cell function
    Takahiro Fujimoto
    Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, Japan
    Anesth Analg 101:1054-9, table of contents. 2005
    ..In conclusion, midazolam and propofol inhibited both chemotaxis and exocytosis of mast cells, while thiopental only inhibited chemotaxis, and ketamine only inhibited exocytosis...
  44. ncbi How to decrease pain at rapid injection of propofol: effectiveness of flurbiprofen
    Tomoki Nishiyama
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Anesth 19:273-6. 2005
    ..In the present study, the most effective method was investigated by adding lidocaine or a nonsteroidal antiinflammatory drug or by changing the solvent...
  45. ncbi [A case of giant thyroid tumor with tracheal stenosis]
    Ju Mizuno
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo 113 8665
    Masui 53:682-6. 2004
    ..Intubation under conscious sedation with midazolam and fentanyl is useful for a patient with a giant thyroid tumor and tracheal stenosis...
  46. ncbi Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Anesth Analg 96:1386-91, table of contents. 2003
    ..In conclusion, intrathecally administered midazolam and bupivacaine had synergistic analgesic effects on acute thermal- or inflammatory-induced pain, with decreased behavioral side effects...
  47. ncbi [Sedation with intravenous midazolam during upper gastrointestinal endoscopy--changes in hemodynamics, oxygen saturation and memory]
    Ju Mizuno
    Pain Relief Center, Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113 8655
    Masui 52:976-80. 2003
    ..In this study, we examined hemodynamics, oxygen saturation and memory during upper gastrointestinal endoscopy under sedation with intravenous midazolam...
  48. ncbi Comparison of hemodynamic and anesthetic effects of hyperbaric bupivacaine and tetracaine in spinal anesthesia
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Anesth 17:218-22. 2003
    ..To compare the anesthetic and hemodynamic effects and the predictive factor of anesthesia level of commonly used preparations of hyperbaric bupivacaine and tetracaine in spinal anesthesia...
  49. ncbi A comparison of liver function after hepatectomy in cirrhotic patients between sevoflurane and isoflurane in anesthesia with nitrous oxide and epidural block
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
    Anesth Analg 98:990-3, table of contents. 2004
    ..Whether sevoflurane might be a better anesthetic when combined with N(2)O and epidural block for cirrhotic patients than isoflurane with respect to liver damage remains to be determined...
  50. ncbi Serum and cerebrospinal fluid concentrations of midazolam after epidural administration in dogs
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    Anesth Analg 96:159-62, table of contents. 2003
    ..2 +/- 4.7 ng/mL), and decreased to 3.6 +/- 3.3 ng/mL at 240 min. In conclusion, epidurally administered midazolam enters CSF, but CSF concentrations are only 3% of those in the systemic circulation...
  51. ncbi Intrathecal clonidine and bupivacaine have synergistic analgesia for acute thermally or inflammatory-induced pain in rats
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
    Anesth Analg 98:1056-61, table of contents. 2004
    ..2 and 0.16 microg) of the formalin test. Side effects were decreased by the combination. These results suggest a favorable combination of intrathecal bupivacaine and clonidine in the management of acute and inflammatory pain...
  52. ncbi A comparison of the clinical usefulness of three different electroencephalogram monitors: Bispectral Index, processed electroencephalogram, and Alaris auditory evoked potentials
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
    Anesth Analg 98:1341-5, table of contents. 2004
    ..The recovery time was shorter in pEEG < A-AEP < BIS. In summary, the BIS had the largest success rate, the A-AEP had the least inappropriateness rate and the largest responsiveness, and the pEEG had the fastest recovery time...
  53. ncbi [A case of ectopic pheochromocytoma of pulmonary origin]
    Takahiro Fujimoto
    Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655
    Masui 53:537-9. 2004
    ..A case of ectopic pheochromocytoma of pulmonary origin was managed with midazolam, propofol, fentanyl and continuous epidural block. Diltiazem, nicardipine and norepinephrine were administered to control blood pressure...
  54. ncbi The A-line ARX index may be a more sensitive detector of arousal than the bispectral index during propofol-fentanyl-nitrous oxide anesthesia: a preliminary investigation
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
    Can J Anaesth 51:539-44. 2004
    ..To compare changes in the A-line ARX index (AAI) by the Alaris AEP monitor(TM) with those of the bispectral index (BIS) during propofol-fentanyl-nitrous oxide anesthesia...
  55. ncbi Spinal neurotoxicity and tolerance after repeated intrathecal administration of YM 872, an AMPA receptor antagonist, in rats
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Japan
    J Anesth 18:113-7. 2004
    ..We examined the spinal neurotoxicity and tolerance of YM 872 analgesia by repeated intrathecal administration in rats...
  56. ncbi [Anesthetic management of a morbidly obese patient with mental retardation]
    Masako Seyama
    Department of Anesthesiology, The University of Tokyo, Tokyo 113 8655
    Masui 55:1225-7. 2006
    ..We successfully used ultrasound sonography to identify spinous process and could insert an epidural catheter at the right place...
  57. ncbi Accidental overdose of midazolam as intramuscular premedication
    Tomoki Nishiyama
    Surgical Center, Institute of Medical Science, and Department of Anesthesiology, The University of Tokyo, Tokyo, Japan
    J Clin Anesth 14:543-5. 2002
    ..However, the situations suggest that we should carefully check the dosage and review the correct procedures, even when using a drug that is considered to be familiar with most practitioners...
  58. ncbi [A new heat and moisture exchanger, Trach-Vent Plus, for patients with spontaneous respiration]
    Tomoki Nishiyama
    Surgical Center, Institute of Medical Science, University of Tokyo, Tokyo 108 8639
    Masui 52:417-9. 2003
    ..This new heat and moisture exchanger, Trach-Vent Plus is useful to administer oxygen to intubated patients breathing spontaneously, especially with tracheostomy...
  59. ncbi Effects of vasodilation on cardiac output measured by PulseCO
    Koichi Yamashita
    Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku Shi, Kochi, 783 8505, Japan
    J Clin Monit Comput 21:335-9. 2007
    ..during cardiac surgery has been reported. In the present study, we investigated the effects of vasodilation by prostaglandin E1 (PGE1) on the relation between cardiac output measured by PulseCO and that by thermodilution...
  60. ncbi [Usefulness of a new nasal cannula with an end-tidal carbon dioxide measuring port]
    Tomoki Nishiyama
    Surgical Center, Institute of Medical Science, University of Tokyo, Tokyo 108 8639
    Masui 52:424-6. 2003
    ..We investigated the usefulness of a new nasal cannula with which EtCO2 can be monitored simultaneously with oxygen delivery...
  61. ncbi Effects of quazepam as a preoperative night hypnotic: comparison with brotizolam
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
    J Anesth 21:7-12. 2007
    ..The purpose of this study was to evaluate the effects of quazepam, a long-acting hypnotic, as a preoperative night medication in comparison with brotizolam, a shortacting hypnotic...
  62. ncbi Electrostatic field can preserve red blood cells in stored blood preparations
    Tomoki Nishiyama
    Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    J Anesth 21:42-6. 2007
    ..We hypothesized that the storage of CRCs under an electrostatic field could keep red blood cells in better condition than conventional storage...
  63. ncbi [Bronchospasm during upper gastrointestinal endoscopy under sedation]
    Ju Mizuno
    Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113 8665
    Masui 52:170-3. 2003
    ..The insertion of upper gastrointestinal endoscope might have induced bronchospasm stimulating distal esophageal afferent vagal reflex partly by regurgitation of gastric acid under sedation...
  64. ncbi Propofol infusion for sedation during spinal anesthesia
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, 7 3 1, Hongo, Tokyo 113 8655, Japan
    J Anesth 21:265-9. 2007
    ..The dose and time course of propofol infusion required to induce rapid sedation without oversedation during spinal anesthesia were investigated...
  65. ncbi Changes in percutaneous oxygen tension induced by spinal anesthesia
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, 7 3 1 Hongo, Tokyo 113 8655, Japan
    J Anesth 21:317-9. 2007
    ..The purpose of this study was to determine whether changes in percutaneous oxygen tension (tcPO(2)) were suitable for checking the level of spinal anesthesia...
  66. ncbi Antithrombin can modulate coagulation, cytokine production, and expression of adhesion molecules in abdominal aortic aneurysm repair surgery
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo, Japan
    Anesth Analg 102:1007-11. 2006
    ..In conclusion, antithrombin could decrease hypercoagulation and inflammatory activation during abdominal aortic aneurysm surgery, which may decrease adverse events...
  67. ncbi [Cardiac arrest during bilateral inguinal herniorrhaphy under epidural anesthesia]
    Kazuhiro Nagao
    Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Nankoku 783 8505
    Masui 53:1404-6. 2004
    ..Vagal reflex induced by bilateral inguinal herniorrhaphy might cause cardiac arrest. We should be careful for vagal reflex during bilateral herniorrhaphy...
  68. ncbi Blood flow velocity of the femoral vein with foot exercise compared to pneumatic foot compression
    Koichi Yamashita
    Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kochi 783 8505, Japan
    J Clin Anesth 17:102-5. 2005
    ..To compare the effects of foot exercise with an intermittent pneumatic foot compression (IPC) device on blood flow velocity of the femoral veins...
  69. ncbi Cardiac output by PulseCO is not interchangeable with thermodilution in patients undergoing OPCAB
    Koichi Yamashita
    Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kohasu, Oko cho, Nankoku Shi, Kochi, 783 8505, Japan
    Can J Anaesth 52:530-4. 2005
    ..To investigate the reliability of cardiac output assessed by arterial pressure waveform (PulseCO) in comparison with bolus thermodilution measurements in patients undergoing off-pump coronary artery bypass grafting (OPCAB)...
  70. ncbi [Does common cold increase perioperative respiratory complications in adults?]
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo
    Masui 54:643-7. 2005
    ..We investigated whether perioperative respiratory complications increase in adults with common cold symptom...
  71. ncbi Comparison of the intracuff pressures of three different tracheostomy tubes
    Tomoki Nishiyama
    Department of Anesthesiology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    J Anesth 19:260-2. 2005
    ..Based on these results, the MERA sofit CLEAR was found to maintain most safely the lowest intracuff pressure to seal the trachea among the three tracheostomy tubes tested...
  72. ncbi [General anesthesia for a patient with Noonan's syndrome and long-term antidepressant therapy]
    Shinji Nakamura
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine, Tokyo 113 8655
    Masui 54:901-3. 2005
    ..This patient presented a problem of difficult intubation as Noonan's syndrome and had a history of a long-term use of antidepressant, which might induce sympathomimetic resistant hypotension...
  73. ncbi [A case report of the laryngeal edema and peripheral cyanosis after extubation of the tracheal tube]
    Keiichi Itatani
    Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo 113 8655
    Masui 52:897-9. 2003
    ..The hemodynamic instability during surgery and cyanosis after extubation might have come from changes of the vascular resistance by sepsis...
  74. ncbi Doxapram produces a dose-dependent reduction in the shivering threshold in rabbits
    Katsumi Okuyama
    Department of Anesthesia, University of Yamanashi, Faculty of Medicine, Tamaho, Yamanashi, Japan
    Anesth Analg 97:759-62. 2003
    ..50 mg x kg(-1) x h(-1) shivered at 33.7 degrees +/- 0.6 degrees C. All the shivering thresholds significantly (P < 0.001) differed from one another. The magnitude of this inhibition, if similar in humans, would be clinically important...
  75. ncbi [General anesthesia for diaphragmatic herniorrhaphy in a patient with myasthenia gravis and severe gibbus]
    Shinji Nakamura
    Department of Anesthesiology, The University of Tokyo, Faculty of Medicine
    Masui 54:1371-2. 2005
    ..Thus, we used sevoflurane and epidural block. We successfully anesthetized a patient for diaphragmatic herniorrhaphy complicated with myasthenia gravis and gibbus by sevoflurane and epidural block...
  76. ncbi Spinally mediated analgesia and receptor binding affinity of epibatidine analogs
    Tomoki Nishiyama
    Department of Anesthesiology, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Eur J Pharmacol 470:27-31. 2003
    ..In summary, the two epibatidine analogs have higher potency ratio of spinally mediated analgesia/side effects than epibatidine...
  77. ncbi Core temperature monitoring with new ventilatory devices
    Takashi Matsukawa
    Department of Anesthesia, University of Yamanashi, Faculty of Medicine, Japan
    Anesth Analg 96:1688-91, table of contents. 2003
    ..5 degrees C was 7% with LMA and 10% with COPA. These results suggest that body temperature measured from the cuffs of COPA or LMAs is sufficiently accurate for routine clinical use...
  78. ncbi [High dose L-dopa infusion during general anesthesia for gastrectomy in a patient with parkinsonism]
    Tetsuya Horai
    Department of Anesthesiology, University of Tokyo, Tokyo 113 8655
    Masui 51:42-5. 2002
    ..However, he developed no complications, which suggests a wide safety range of levodopa. In conclusion, high dose levodopa infusion was effective in controlling the symptoms of Parkinsonism during general anesthesia...