Research Topics
| Tetsuhito MurataSummaryAffiliation: University of Fukui Country: Japan Publications
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Detail Information
Publications
Dynamic changes in glucose metabolism by lactate loading as revealed by a positron autoradiography technique using rat living brain slicesT Murata
Biomedical Imaging Research Center, Fukui Medical University, Japan
Neurosci Lett 249:155-8. 1998..The lactate concentration in the surrounding medium decreased after lactate loading. Hence brain tissue preferentially uses lactate over glucose under normoxic and euglycemic condition...- White coat phenomenon, anxiety and endothelial function in healthy normotensive elderly subjectsTetsuhito Murata
Department of Neuropsychiatry, University of Fukui, Japan
Blood Press 15:88-92. 2006..We studied the possible association between WCP and anxiety or vascular function in normotensive elderly subjects without major cardiovascular risk factors... - Effects of haloperidol and its pyridinium metabolite on plasma membrane permeability and fluidity in the rat brainTetsuhito Murata
Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
Prog Neuropsychopharmacol Biol Psychiatry 31:848-57. 2007..These results suggest that HPP(+) has a higher potency to induce plasma membrane damage than HP, and these actions of HPP(+) may partly underlie the pathogenesis of HP-induced extrapyramidal side effects... - A comparative study of the plasma membrane permeabilization and fluidization induced by antipsychotic drugs in the rat brainTetsuhito Murata
Department of Neuropsychiatry, University of Fukui, Fukui, Japan
Int J Neuropsychopharmacol 10:683-9. 2007.... - MRI white matter hyperintensities, (1)H-MR spectroscopy and cognitive function in geriatric depression: a comparison of early- and late-onset casesT Murata
Department of Neuropsychiatry, Fukui Medical University, Matsuoka, Japan
Int J Geriatr Psychiatry 16:1129-35. 2001.... - Serial MRI and (1)H-MRS of Wernicke's encephalopathy: report of a case with remarkable cerebellar lesions on MRIT Murata
Department of Neuropsychiatry, Fukui Medical University, 23 3 Shimoaizuki, Matsuoka, Fukui 910 1193, Japan
Psychiatry Res 108:49-55. 2001..It is suggested that serial MRI/(1)H-MRS observation may be helpful in determining the neuronal viability of Wernicke's encephalopathy and the prognostic implications of sequelae such as Korsakoff's syndrome and cerebellar ataxia... 
Neuronal damage in the interval form of CO poisoning determined by serial diffusion weighted magnetic resonance imaging plus 1H-magnetic resonance spectroscopyT Murata
Department of Neuropsychiatry, Fukui Medical University, Matsuoka, Fukui 910 1193, Japan
J Neurol Neurosurg Psychiatry 71:250-3. 2001..Serial diffusion weighted imaging plus 1H-MRS measurements are useful in determining the tissue damage and long term outcome of delayed sequelae associated with the interval form of CO poisoning...- Neurotoxicity after hypoxia/during ischemia due to glutamate with/without free radicals as revealed by dynamic changes in glucose metabolismT Murata
Biomedical Imaging Research Center, Fukui Medical University, Matsuoka cho, 910 1193, Fukui, Japan
Brain Res 865:259-63. 2000.... - Dynamic changes in glucose metabolism of living rat brain slices induced by hypoxia and neurotoxic chemical-loading revealed by positron autoradiographyT Murata
Biomedical Imaging Research Center, and Department of Neuropsychiatry, Fukui Medical University, Japan
J Neural Transm 106:1075-87. 1999.... - Individual trait anxiety levels characterizing the properties of zen meditationT Murata
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Neuropsychobiology 50:189-94. 2004..These results suggest that lower trait anxiety more readily induces meditation with a predominance of internalized attention, while higher trait anxiety more readily induces meditation with a predominance of relaxation... 
Effects of vitamin E supplementation on plasma membrane permeabilization and fluidization induced by chlorpromazine in the rat brainNobuyuki Maruoka
Department of Neuropsychiatry, University of Fukui, Fukui, Japan
J Psychopharmacol 22:119-27. 2008..CPZ can reduce plasma membrane integrity in the brain, and this reduction can be prevented by vitamin E via its membrane-stabilizing properties, not via its antioxidant activity...- The clinical significance of abnormal diurnal blood pressure variation in healthy late middle-aged and older adultsToshihiko Hamada
Department of Clinical and Laboratory Science, University of Fukui, Fukui, Japan
Blood Press 17:134-40. 2008..Conclusion. In healthy elderly subjects, the extreme-dipper type may reflect a decrease in endothelial function, i.e. initial stage atherosclerosis, rather than the dipper type... - Application of a multifractal analysis to study brain white matter abnormalities of schizophrenia on T2-weighted magnetic resonance imagingTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Psychiatry Res 171:177-88. 2009..Multifractal analysis reveals abnormal patterns of WM structures in schizophrenia that could be implicated in the disorder's etiology... - Effects of chlorpromazine on plasma membrane permeability and fluidity in the rat brain: a dynamic positron autoradiography and fluorescence polarization studyNobuyuki Maruoka
Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
Prog Neuropsychopharmacol Biol Psychiatry 31:178-86. 2007..CPZ loading dose-dependently increased both membrane permeability and membrane fluidity, which suggested the involvement of a perturbation of membrane order in the mechanisms of membrane destabilization induced by antipsychotic drugs... - Different mechanisms of hypoxic injury on white matter and gray matter as revealed by dynamic changes in glucose metabolism in ratsNaoto Omata
Department of Neuropsychiatry, Fukui Medical University, Fukui 910-1193, Japan
Neurosci Lett 353:148-52. 2003..e. the involvement of both glutamate and free radicals in gray matter, and the more selective involvement of free radicals in white matter... - Multifractal analysis of deep white matter microstructural changes on MRI in relation to early-stage atherosclerosisTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan
Neuroimage 32:1158-66. 2006.... - Associations between trait anxiety, insulin resistance, and atherosclerosis in the elderly: a pilot cross-sectional studyKosuke Narita
Department of Neuropsychiatry, University of Fukui, Eiheiji cho, Fukui 910 1193, Japan
Psychoneuroendocrinology 33:305-12. 2008..This pilot study, with a cross-sectional design, supports the promising role of IR for clarifying the pathophysiological mechanism by which anxiety contributes to an increasing risk of atherosclerosis... - Changes in EEG and autonomic nervous activity during meditation and their association with personality traitsTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Matsuoka-cho, Fukui 910-1193, Japan
Int J Psychophysiol 55:199-207. 2005..These results suggest that internalized attention and mindfulness as two major core factors of behaviors of mind during meditation are characterized by different combinations of psychophysiological properties and personality traits... - Assessment of EEG dynamical complexity in Alzheimer's disease using multiscale entropyTomoyuki Mizuno
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Clin Neurophysiol 121:1438-46. 2010..To test this method as an aid to elucidating the pathophysiology of Alzheimer's disease (AD), we examined MSE in resting state EEG activity in comparison with traditional EEG analysis... - Association between trait anxiety and endothelial function observed in elderly males but not in young malesKosuke Narita
Department of Neuropsychiatry, University of Fukui, Fukui, Japan
Int Psychogeriatr 19:947-54. 2007..The present study was intended to examine whether an association exists between trait anxiety and endothelial function in healthy young and elderly subjects... - Antipsychotics reverse abnormal EEG complexity in drug-naive schizophrenia: a multiscale entropy analysisTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
Neuroimage 51:173-82. 2010..These findings show that entropy-based analytic methods may serve as a novel approach for characterizing and understanding abnormal cortical dynamics in schizophrenia and elucidating the therapeutic mechanisms of antipsychotics... - Age-related variation in EEG complexity to photic stimulation: a multiscale entropy analysisTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
Clin Neurophysiol 120:476-83. 2009.... - The association between anger-related personality trait and cardiac autonomic response abnormalities in elderly subjectsKosuke Narita
Department of Neuropsychiatry, University of Fukui, Fukui, Japan
Eur Arch Psychiatry Clin Neurosci 257:325-9. 2007.... - Hypoxic tolerance induction in rat brain slices following hypoxic preconditioning due to expression of neuroprotective proteins as revealed by dynamic changes in glucose metabolismNaoto Omata
Department of Neuropsychiatry, Fukui Medical University, Fukui 910-1193, Japan
Neurosci Lett 329:205-8. 2002..In addition, profiling of gene expression using an Atlas Rat Stress Array suggested the involvement of the expression of genes such as stress protein in hypoxic tolerance induction... - Biphasic mechanism of the toxicity induced by 1-methyl-4-phenylpyridinium ion (MPP+) as revealed by dynamic changes in glucose metabolism in rat brain slicesNobuyuki Maruoka
Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
Neurotoxicology 28:672-8. 2007.... - Interactions among higher trait anxiety, sympathetic activity, and endothelial function in the elderlyKosuke Narita
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Matsuoka cho, Yoshida gun, Fukui 910 1193, Japan
J Psychiatr Res 41:418-27. 2007..This finding may be useful in clarifying the pathophysiological mechanism by which anxiety is associated with increased risks for atherosclerosis and CVD... - Smaller insula and inferior frontal volumes in young adults with pervasive developmental disordersHirotaka Kosaka
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, 910 1193, Japan
Neuroimage 50:1357-63. 2010..These smaller GM volumes in high-functioning PDD subjects may reflect the clinical features of PDD itself, rather than FSIQ... - Relationship between plasma leptin level and brain structure in elderly: a voxel-based morphometric studyKosuke Narita
Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
Biol Psychiatry 65:992-4. 2009..Recent accumulating lines of evidence reveal that leptin is associated with synaptic plasticity and neuroprotective activity in the brain... - Hypoxic tolerance induction in rat brain slices following 3-nitropropionic acid pretreatment as revealed by dynamic changes in glucose metabolismNobuyuki Maruoka
Department of Neuropsychiatry, Fukui Medical University, Fukui, Japan
Neurosci Lett 319:83-6. 2002.... - Plasma levels of adiponectin and tumor necrosis factor-alpha in patients with remitted major depression receiving long-term maintenance antidepressant therapyKosuke Narita
Department of Neuropsychiatry, University of Fukui, Fukui 910-1193, Japan
Prog Neuropsychopharmacol Biol Psychiatry 30:1159-62. 2006..This preliminary cross-sectional study suggests the possibility that maintenance antidepressant therapy may have anti-inflammatory effects and prevent the development of atherosclerosis... - Quantitative evaluation of age-related white matter microstructural changes on MRI by multifractal analysisTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, Japan
J Neurol Sci 225:33-7. 2004.... - Effect of dietary zinc deficiency on ischemic vulnerability of the brainNaoto Omata
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
Neurosci Lett 531:10-3. 2012..These findings, obtained for all analyzed brain regions, suggest that dietary zinc deficiency increased ischemic vulnerability in the brain, and that glutamate might contribute to this effect through activation of the NMDA receptor... - Adiponectin multimer distribution, not absolute amount of plasma, correlates with depression severity in healthy elderly subjectsKosuke Narita
Department of Neuropsychiatry, University of Fukui, Eiheiji cho, Fukui 910 1193, Japan
Prog Neuropsychopharmacol Biol Psychiatry 32:124-7. 2008.... - Region-specific causal mechanism in the effects of ammonia on cerebral glucose metabolism in the rat brainNobuyuki Maruoka
Department of Neuropsychiatry, University of Fukui, Fukui, Japan
J Neural Transm 120:375-82. 2013..These results suggested that NMDA receptor activation is responsible for the impairment of glucose metabolism induced by ammonia specifically in cerebellum... - Switching to aripiprazole in subjects with pervasive developmental disorders showing tolerability issues with risperidoneMakoto Ishitobi
Department of Neuropsychiatry, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
Prog Neuropsychopharmacol Biol Psychiatry 37:128-31. 2012..This retrospective study was designed to examine children and adolescents with PDD experiencing tolerability issues with risperidone treatment, and thereby assess the efficacy and tolerability of switching to aripiprazole... - Effects of antidepressants and mood stabilizers on serum levels of adiponectinNaoto Omata
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
Neuro Endocrinol Lett 33:1-2. 2012..This difference of these drugs' effectiveness on serum adiponectin might contribute to their differences of action mechanisms and therapeutic effects... - A case of diffuse neurofibrillary tangles with calcificationKosuke Narita
Department of Neuropsychiatry, Fukui Medical University, Fukui, Japan
Psychiatry Clin Neurosci 56:117-20. 2002..The characteristics of psychiatric symptoms and neuroradiological findings in DNTC are discussed... - Opposite effects of SSRIs and tandospirone in the treatment of REM sleep behavior disorderTetsuya Takahashi
Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui 910 1193, Japan
Sleep Med 9:317-9. 2008..We report on the effects of these serotonin-modulating agents, which yield clues to a possible pharmacological approach to RBD... - Age-related differences in the medial temporal lobe responses to emotional faces as revealed by fMRITetsuya Iidaka
Biomedical Imaging Research Center, Fukui Medical University, Japan
Hippocampus 12:352-62. 2002..The parieto-occipital lobe, which has been found to be involved in face processing, also showed a functional decline associated with aging... - Hypomanic switching during influenza infection without intracranial infection in an adolescent patient with bipolar disorderMakoto Ishitobi
Department of Neuropsychiatry, University of Fukui, Fukui, Japan
Pediatr Emerg Care 27:652-3. 2011.... - Successful treatment of blepharospasm with tandospirone, a 5-HT1A partial agonist: a case reportTetsuya Takahashi
Mov Disord 23:151-2. 2008 - Understanding of cerebral energy metabolism by dynamic living brain slice imaging system with [18F]FDGMikako Ogawa
Photon Medical Research Center, Hamamatsu University School of Medicine, Laboratory of Genome Bio-Photonics, 1-20-1 Handayama, Hamamatsu 431-3192, Japan
Neurosci Res 52:357-61. 2005.... - Effectiveness of serotonin (5-HT)1A receptor agonist in a patient with psychogenic apneusisJiro Onizuka
J Clin Psychopharmacol 22:334-7. 2002 - Demonstration of competition between endogenous dopamine and [11C]raclopride binding in in vitro brain slices using a dynamic autoradiography techniqueToru Sasaki
Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo 173 0022, Japan
Synapse 44:42-50. 2002..These results provide supportive evidence for in vivo binding competition between radioligand and endogenous neurotransmitter... - A patient with lithium intoxication developing at therapeutic serum lithium levels and persistent delirium after discontinuation of its administrationNaoto Omata
Gen Hosp Psychiatry 25:53-5. 2003 - Clonazepam augmentation therapy in a male at early adolescence with rapid cycling bipolar disorderTakahito Sugimoto
Gen Hosp Psychiatry 25:57-9. 2003 - Association of abnormal diurnal blood pressure variation with the development of silent cerebral infarction in patients with late-life-onset depressionTetsuhito Murata
Gen Hosp Psychiatry 25:298-300. 2003 - Role of lactate in the brain energy metabolism: revealed by BioradiographyMasaaki Tanaka
Department of Physiology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan
Neurosci Res 48:13-20. 2004..In contrast, when 0.5 mM 4-CIN was applied to the normal glucose solution, [18F]FDG uptake rate increased. These results suggest that exogenous and endogenous lactate can substitute for glucose in the brain... - Successful treatment of intractable hiccups with serotonin (5-HT)1A receptor agonistTetsuya Takahashi
J Neurol 251:486-7. 2004 - Depressive psychosis: clinical usefulness of MR spectroscopy data in predicting prognosisHirotsugu Kado
Department of Radiology, Akita Research Institute for Brain and Blood Vessels, 6-10 Kubotamachi, Sensyu, Akita 010-0874, Japan
Radiology 238:248-55. 2006.... - [Changes in autonomic function and EEG power during mental arithmetic task and their mutual relationship]Toshihiko Hamada
Department of Clinical Laboratory, Fukui University Hospital, Yoshida-gun, Fukui-pref 910-1193
Rinsho Byori 54:329-34. 2006..These results suggest that specific correlated relationships exist between the change in autonomic nervous activity and EEG power depending on the difference in mental task (i.e., meditation or MA)... - [The association between autonomic response status and the changes in EEG activity during mental arithmetic task]Yuka Ohtake
Department of Clinical Laboratory, Fukui University Hospital, Yoshida gun, Fukui pref 910 1193
Rinsho Byori 55:1075-9. 2007..These results suggest that there are correlations between the autonomic response in an individual and EEG power changes during MA tasks...