Tetsuhito Murata

Summary

Affiliation: University of Fukui
Country: Japan

Publications

  1. ncbi request reprint Dynamic changes in glucose metabolism by lactate loading as revealed by a positron autoradiography technique using rat living brain slices
    T Murata
    Biomedical Imaging Research Center, Fukui Medical University, Japan
    Neurosci Lett 249:155-8. 1998
  2. ncbi request reprint Effects of haloperidol and its pyridinium metabolite on plasma membrane permeability and fluidity in the rat brain
    Tetsuhito Murata
    Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:848-57. 2007
  3. ncbi request reprint A comparative study of the plasma membrane permeabilization and fluidization induced by antipsychotic drugs in the rat brain
    Tetsuhito Murata
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    Int J Neuropsychopharmacol 10:683-9. 2007
  4. ncbi request reprint Individual trait anxiety levels characterizing the properties of zen meditation
    T Murata
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Neuropsychobiology 50:189-94. 2004
  5. ncbi request reprint White coat phenomenon, anxiety and endothelial function in healthy normotensive elderly subjects
    Tetsuhito Murata
    Department of Neuropsychiatry, University of Fukui, Japan
    Blood Press 15:88-92. 2006
  6. ncbi request reprint MRI white matter hyperintensities, (1)H-MR spectroscopy and cognitive function in geriatric depression: a comparison of early- and late-onset cases
    T Murata
    Department of Neuropsychiatry, Fukui Medical University, Matsuoka, Japan
    Int J Geriatr Psychiatry 16:1129-35. 2001
  7. ncbi request reprint Serial MRI and (1)H-MRS of Wernicke's encephalopathy: report of a case with remarkable cerebellar lesions on MRI
    T Murata
    Department of Neuropsychiatry, Fukui Medical University, 23 3 Shimoaizuki, Matsuoka, Fukui 910 1193, Japan
    Psychiatry Res 108:49-55. 2001
  8. pmc Neuronal damage in the interval form of CO poisoning determined by serial diffusion weighted magnetic resonance imaging plus 1H-magnetic resonance spectroscopy
    T Murata
    Department of Neuropsychiatry, Fukui Medical University, Matsuoka, Fukui 910 1193, Japan
    J Neurol Neurosurg Psychiatry 71:250-3. 2001
  9. ncbi request reprint Neurotoxicity after hypoxia/during ischemia due to glutamate with/without free radicals as revealed by dynamic changes in glucose metabolism
    T Murata
    Biomedical Imaging Research Center, Fukui Medical University, Matsuoka cho, 910 1193, Fukui, Japan
    Brain Res 865:259-63. 2000
  10. ncbi request reprint Dynamic changes in glucose metabolism of living rat brain slices induced by hypoxia and neurotoxic chemical-loading revealed by positron autoradiography
    T Murata
    Biomedical Imaging Research Center, and Department of Neuropsychiatry, Fukui Medical University, Japan
    J Neural Transm 106:1075-87. 1999

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Dynamic changes in glucose metabolism by lactate loading as revealed by a positron autoradiography technique using rat living brain slices
    T Murata
    Biomedical Imaging Research Center, Fukui Medical University, Japan
    Neurosci Lett 249:155-8. 1998
    ..The lactate concentration in the surrounding medium decreased after lactate loading. Hence brain tissue preferentially uses lactate over glucose under normoxic and euglycemic condition...
  2. ncbi request reprint Effects of haloperidol and its pyridinium metabolite on plasma membrane permeability and fluidity in the rat brain
    Tetsuhito Murata
    Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:848-57. 2007
    ..These results suggest that HPP(+) has a higher potency to induce plasma membrane damage than HP, and these actions of HPP(+) may partly underlie the pathogenesis of HP-induced extrapyramidal side effects...
  3. ncbi request reprint A comparative study of the plasma membrane permeabilization and fluidization induced by antipsychotic drugs in the rat brain
    Tetsuhito Murata
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    Int J Neuropsychopharmacol 10:683-9. 2007
    ....
  4. ncbi request reprint Individual trait anxiety levels characterizing the properties of zen meditation
    T Murata
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Neuropsychobiology 50:189-94. 2004
    ..These results suggest that lower trait anxiety more readily induces meditation with a predominance of internalized attention, while higher trait anxiety more readily induces meditation with a predominance of relaxation...
  5. ncbi request reprint White coat phenomenon, anxiety and endothelial function in healthy normotensive elderly subjects
    Tetsuhito Murata
    Department of Neuropsychiatry, University of Fukui, Japan
    Blood Press 15:88-92. 2006
    ..We studied the possible association between WCP and anxiety or vascular function in normotensive elderly subjects without major cardiovascular risk factors...
  6. ncbi request reprint MRI white matter hyperintensities, (1)H-MR spectroscopy and cognitive function in geriatric depression: a comparison of early- and late-onset cases
    T Murata
    Department of Neuropsychiatry, Fukui Medical University, Matsuoka, Japan
    Int J Geriatr Psychiatry 16:1129-35. 2001
    ....
  7. ncbi request reprint Serial MRI and (1)H-MRS of Wernicke's encephalopathy: report of a case with remarkable cerebellar lesions on MRI
    T Murata
    Department of Neuropsychiatry, Fukui Medical University, 23 3 Shimoaizuki, Matsuoka, Fukui 910 1193, Japan
    Psychiatry Res 108:49-55. 2001
    ..It is suggested that serial MRI/(1)H-MRS observation may be helpful in determining the neuronal viability of Wernicke's encephalopathy and the prognostic implications of sequelae such as Korsakoff's syndrome and cerebellar ataxia...
  8. pmc Neuronal damage in the interval form of CO poisoning determined by serial diffusion weighted magnetic resonance imaging plus 1H-magnetic resonance spectroscopy
    T Murata
    Department of Neuropsychiatry, Fukui Medical University, Matsuoka, Fukui 910 1193, Japan
    J Neurol Neurosurg Psychiatry 71:250-3. 2001
    ..Serial diffusion weighted imaging plus 1H-MRS measurements are useful in determining the tissue damage and long term outcome of delayed sequelae associated with the interval form of CO poisoning...
  9. ncbi request reprint Neurotoxicity after hypoxia/during ischemia due to glutamate with/without free radicals as revealed by dynamic changes in glucose metabolism
    T Murata
    Biomedical Imaging Research Center, Fukui Medical University, Matsuoka cho, 910 1193, Fukui, Japan
    Brain Res 865:259-63. 2000
    ....
  10. ncbi request reprint Dynamic changes in glucose metabolism of living rat brain slices induced by hypoxia and neurotoxic chemical-loading revealed by positron autoradiography
    T Murata
    Biomedical Imaging Research Center, and Department of Neuropsychiatry, Fukui Medical University, Japan
    J Neural Transm 106:1075-87. 1999
    ....
  11. doi request reprint Effects of vitamin E supplementation on plasma membrane permeabilization and fluidization induced by chlorpromazine in the rat brain
    Nobuyuki Maruoka
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    J Psychopharmacol 22:119-27. 2008
    ..CPZ can reduce plasma membrane integrity in the brain, and this reduction can be prevented by vitamin E via its membrane-stabilizing properties, not via its antioxidant activity...
  12. doi request reprint Effect of dietary zinc deficiency on ischemic vulnerability of the brain
    Naoto Omata
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
    Neurosci Lett 531:10-3. 2012
    ..These findings, obtained for all analyzed brain regions, suggest that dietary zinc deficiency increased ischemic vulnerability in the brain, and that glutamate might contribute to this effect through activation of the NMDA receptor...
  13. doi request reprint The clinical significance of abnormal diurnal blood pressure variation in healthy late middle-aged and older adults
    Toshihiko Hamada
    Department of Clinical and Laboratory Science, University of Fukui, Fukui, Japan
    Blood Press 17:134-40. 2008
    ..Conclusion. In healthy elderly subjects, the extreme-dipper type may reflect a decrease in endothelial function, i.e. initial stage atherosclerosis, rather than the dipper type...
  14. ncbi request reprint Effects of chlorpromazine on plasma membrane permeability and fluidity in the rat brain: a dynamic positron autoradiography and fluorescence polarization study
    Nobuyuki Maruoka
    Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:178-86. 2007
    ..CPZ loading dose-dependently increased both membrane permeability and membrane fluidity, which suggested the involvement of a perturbation of membrane order in the mechanisms of membrane destabilization induced by antipsychotic drugs...
  15. ncbi request reprint Different mechanisms of hypoxic injury on white matter and gray matter as revealed by dynamic changes in glucose metabolism in rats
    Naoto Omata
    Department of Neuropsychiatry, Fukui Medical University, Fukui 910 1193, Japan
    Neurosci Lett 353:148-52. 2003
    ..e. the involvement of both glutamate and free radicals in gray matter, and the more selective involvement of free radicals in white matter...
  16. doi request reprint Application of a multifractal analysis to study brain white matter abnormalities of schizophrenia on T2-weighted magnetic resonance imaging
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Psychiatry Res 171:177-88. 2009
    ..Multifractal analysis reveals abnormal patterns of WM structures in schizophrenia that could be implicated in the disorder's etiology...
  17. ncbi request reprint Multifractal analysis of deep white matter microstructural changes on MRI in relation to early-stage atherosclerosis
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23 3 Shimoaizuki, Matsuoka cho, Yoshida gun, Fukui 910 1193, Japan
    Neuroimage 32:1158-66. 2006
    ....
  18. doi request reprint Region-specific causal mechanism in the effects of ammonia on cerebral glucose metabolism in the rat brain
    Nobuyuki Maruoka
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    J Neural Transm 120:375-82. 2013
    ..These results suggested that NMDA receptor activation is responsible for the impairment of glucose metabolism induced by ammonia specifically in cerebellum...
  19. doi request reprint Associations between trait anxiety, insulin resistance, and atherosclerosis in the elderly: a pilot cross-sectional study
    Kosuke Narita
    Department of Neuropsychiatry, University of Fukui, Eiheiji cho, Fukui 910 1193, Japan
    Psychoneuroendocrinology 33:305-12. 2008
    ..This pilot study, with a cross-sectional design, supports the promising role of IR for clarifying the pathophysiological mechanism by which anxiety contributes to an increasing risk of atherosclerosis...
  20. ncbi request reprint Association between trait anxiety and endothelial function observed in elderly males but not in young males
    Kosuke Narita
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    Int Psychogeriatr 19:947-54. 2007
    ..The present study was intended to examine whether an association exists between trait anxiety and endothelial function in healthy young and elderly subjects...
  21. pmc Antipsychotics reverse abnormal EEG complexity in drug-naive schizophrenia: a multiscale entropy analysis
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Neuroimage 51:173-82. 2010
    ..These findings show that entropy-based analytic methods may serve as a novel approach for characterizing and understanding abnormal cortical dynamics in schizophrenia and elucidating the therapeutic mechanisms of antipsychotics...
  22. ncbi request reprint Changes in EEG and autonomic nervous activity during meditation and their association with personality traits
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Matsuoka cho, Fukui 910 1193, Japan
    Int J Psychophysiol 55:199-207. 2005
    ..These results suggest that internalized attention and mindfulness as two major core factors of behaviors of mind during meditation are characterized by different combinations of psychophysiological properties and personality traits...
  23. pmc Assessment of EEG dynamical complexity in Alzheimer's disease using multiscale entropy
    Tomoyuki Mizuno
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Clin Neurophysiol 121:1438-46. 2010
    ..To test this method as an aid to elucidating the pathophysiology of Alzheimer's disease (AD), we examined MSE in resting state EEG activity in comparison with traditional EEG analysis...
  24. ncbi request reprint The association between anger-related personality trait and cardiac autonomic response abnormalities in elderly subjects
    Kosuke Narita
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    Eur Arch Psychiatry Clin Neurosci 257:325-9. 2007
    ....
  25. pmc Age-related variation in EEG complexity to photic stimulation: a multiscale entropy analysis
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
    Clin Neurophysiol 120:476-83. 2009
    ....
  26. ncbi request reprint Hypoxic tolerance induction in rat brain slices following hypoxic preconditioning due to expression of neuroprotective proteins as revealed by dynamic changes in glucose metabolism
    Naoto Omata
    Department of Neuropsychiatry, Fukui Medical University, Fukui 910 1193, Japan
    Neurosci Lett 329:205-8. 2002
    ..In addition, profiling of gene expression using an Atlas Rat Stress Array suggested the involvement of the expression of genes such as stress protein in hypoxic tolerance induction...
  27. ncbi request reprint Biphasic mechanism of the toxicity induced by 1-methyl-4-phenylpyridinium ion (MPP+) as revealed by dynamic changes in glucose metabolism in rat brain slices
    Nobuyuki Maruoka
    Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
    Neurotoxicology 28:672-8. 2007
    ....
  28. doi request reprint Mania: not the opposite of depression, but an extension? Neuronal plasticity and polarity
    Tomoyuki Mizuno
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
    Med Hypotheses 81:175-9. 2013
    ..Based on this hypothesis, it is expected that the pathophysiology of mood disorder and clinical mechanism of mood stabilizers and antidepressants can be understood in an integrated manner. ..
  29. ncbi request reprint Interactions among higher trait anxiety, sympathetic activity, and endothelial function in the elderly
    Kosuke Narita
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Matsuoka cho, Yoshida gun, Fukui 910 1193, Japan
    J Psychiatr Res 41:418-27. 2007
    ..This finding may be useful in clarifying the pathophysiological mechanism by which anxiety is associated with increased risks for atherosclerosis and CVD...
  30. doi request reprint Smaller insula and inferior frontal volumes in young adults with pervasive developmental disorders
    Hirotaka Kosaka
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, 910 1193, Japan
    Neuroimage 50:1357-63. 2010
    ..These smaller GM volumes in high-functioning PDD subjects may reflect the clinical features of PDD itself, rather than FSIQ...
  31. ncbi request reprint Plasma levels of adiponectin and tumor necrosis factor-alpha in patients with remitted major depression receiving long-term maintenance antidepressant therapy
    Kosuke Narita
    Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 30:1159-62. 2006
    ..This preliminary cross-sectional study suggests the possibility that maintenance antidepressant therapy may have anti-inflammatory effects and prevent the development of atherosclerosis...
  32. ncbi request reprint Hypoxic tolerance induction in rat brain slices following 3-nitropropionic acid pretreatment as revealed by dynamic changes in glucose metabolism
    Nobuyuki Maruoka
    Department of Neuropsychiatry, Fukui Medical University, Fukui, Japan
    Neurosci Lett 319:83-6. 2002
    ....
  33. doi request reprint Relationship between plasma leptin level and brain structure in elderly: a voxel-based morphometric study
    Kosuke Narita
    Department of Neuropsychiatry, University of Fukui, Fukui 910 1193, Japan
    Biol Psychiatry 65:992-4. 2009
    ..Recent accumulating lines of evidence reveal that leptin is associated with synaptic plasticity and neuroprotective activity in the brain...
  34. ncbi request reprint Quantitative evaluation of age-related white matter microstructural changes on MRI by multifractal analysis
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui 910 1193, Japan
    J Neurol Sci 225:33-7. 2004
    ....
  35. ncbi request reprint Adiponectin multimer distribution, not absolute amount of plasma, correlates with depression severity in healthy elderly subjects
    Kosuke Narita
    Department of Neuropsychiatry, University of Fukui, Eiheiji cho, Fukui 910 1193, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 32:124-7. 2008
    ....
  36. doi request reprint Switching to aripiprazole in subjects with pervasive developmental disorders showing tolerability issues with risperidone
    Makoto Ishitobi
    Department of Neuropsychiatry, University of Fukui, 23 3 Matsuokashimoaizuki, Eiheiji cho, Yoshida gun, Fukui 910 1193, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 37:128-31. 2012
    ..This retrospective study was designed to examine children and adolescents with PDD experiencing tolerability issues with risperidone treatment, and thereby assess the efficacy and tolerability of switching to aripiprazole...
  37. ncbi request reprint Effects of antidepressants and mood stabilizers on serum levels of adiponectin
    Naoto Omata
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
    Neuro Endocrinol Lett 33:1-2. 2012
    ..This difference of these drugs' effectiveness on serum adiponectin might contribute to their differences of action mechanisms and therapeutic effects...
  38. ncbi request reprint Opposite effects of SSRIs and tandospirone in the treatment of REM sleep behavior disorder
    Tetsuya Takahashi
    Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui 910 1193, Japan
    Sleep Med 9:317-9. 2008
    ..We report on the effects of these serotonin-modulating agents, which yield clues to a possible pharmacological approach to RBD...
  39. ncbi request reprint A case of diffuse neurofibrillary tangles with calcification
    Kosuke Narita
    Department of Neuropsychiatry, Fukui Medical University, Fukui, Japan
    Psychiatry Clin Neurosci 56:117-20. 2002
    ..The characteristics of psychiatric symptoms and neuroradiological findings in DNTC are discussed...
  40. ncbi request reprint Age-related differences in the medial temporal lobe responses to emotional faces as revealed by fMRI
    Tetsuya Iidaka
    Biomedical Imaging Research Center, Fukui Medical University, Japan
    Hippocampus 12:352-62. 2002
    ..The parieto-occipital lobe, which has been found to be involved in face processing, also showed a functional decline associated with aging...
  41. doi request reprint Hypomanic switching during influenza infection without intracranial infection in an adolescent patient with bipolar disorder
    Makoto Ishitobi
    Department of Neuropsychiatry, University of Fukui, Fukui, Japan
    Pediatr Emerg Care 27:652-3. 2011
    ....
  42. ncbi request reprint Effectiveness of serotonin (5-HT)1A receptor agonist in a patient with psychogenic apneusis
    Jiro Onizuka
    J Clin Psychopharmacol 22:334-7. 2002
  43. ncbi request reprint Successful treatment of blepharospasm with tandospirone, a 5-HT1A partial agonist: a case report
    Tetsuya Takahashi
    Mov Disord 23:151-2. 2008
  44. ncbi request reprint Understanding of cerebral energy metabolism by dynamic living brain slice imaging system with [18F]FDG
    Mikako Ogawa
    Photon Medical Research Center, Hamamatsu University School of Medicine, Laboratory of Genome Bio Photonics, 1 20 1 Handayama, Hamamatsu 431 3192, Japan
    Neurosci Res 52:357-61. 2005
    ....
  45. ncbi request reprint Demonstration of competition between endogenous dopamine and [11C]raclopride binding in in vitro brain slices using a dynamic autoradiography technique
    Toru Sasaki
    Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo 173 0022, Japan
    Synapse 44:42-50. 2002
    ..These results provide supportive evidence for in vivo binding competition between radioligand and endogenous neurotransmitter...
  46. ncbi request reprint [The association between autonomic response status and the changes in EEG activity during mental arithmetic task]
    Yuka Ohtake
    Department of Clinical Laboratory, Fukui University Hospital, Yoshida gun, Fukui pref 910 1193
    Rinsho Byori 55:1075-9. 2007
    ..These results suggest that there are correlations between the autonomic response in an individual and EEG power changes during MA tasks...
  47. ncbi request reprint A patient with lithium intoxication developing at therapeutic serum lithium levels and persistent delirium after discontinuation of its administration
    Naoto Omata
    Gen Hosp Psychiatry 25:53-5. 2003
  48. ncbi request reprint Clonazepam augmentation therapy in a male at early adolescence with rapid cycling bipolar disorder
    Takahito Sugimoto
    Gen Hosp Psychiatry 25:57-9. 2003
  49. ncbi request reprint Association of abnormal diurnal blood pressure variation with the development of silent cerebral infarction in patients with late-life-onset depression
    Tetsuhito Murata
    Gen Hosp Psychiatry 25:298-300. 2003
  50. ncbi request reprint Role of lactate in the brain energy metabolism: revealed by Bioradiography
    Masaaki Tanaka
    Department of Physiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahimachi, Abeno Ku, Osaka 545 8585, Japan
    Neurosci Res 48:13-20. 2004
    ..In contrast, when 0.5 mM 4-CIN was applied to the normal glucose solution, [18F]FDG uptake rate increased. These results suggest that exogenous and endogenous lactate can substitute for glucose in the brain...
  51. ncbi request reprint Successful treatment of intractable hiccups with serotonin (5-HT)1A receptor agonist
    Tetsuya Takahashi
    J Neurol 251:486-7. 2004
  52. ncbi request reprint [Changes in autonomic function and EEG power during mental arithmetic task and their mutual relationship]
    Toshihiko Hamada
    Department of Clinical Laboratory, Fukui University Hospital, Yoshida gun, Fukui pref 910 1193
    Rinsho Byori 54:329-34. 2006
    ..These results suggest that specific correlated relationships exist between the change in autonomic nervous activity and EEG power depending on the difference in mental task (i.e., meditation or MA)...
  53. ncbi request reprint Depressive psychosis: clinical usefulness of MR spectroscopy data in predicting prognosis
    Hirotsugu Kado
    Department of Radiology, Akita Research Institute for Brain and Blood Vessels, 6 10 Kubotamachi, Sensyu, Akita 010 0874, Japan
    Radiology 238:248-55. 2006
    ..To prospectively assess the usefulness of magnetic resonance (MR) spectroscopy data acquired before the initiation of medical therapy in predicting prognosis in patients with depressive psychosis...