Masaki Mori

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. pmc Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis
    Masaki Mori
    Division of Gene Therapy Science and Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Osaka 565 0871, Japan
    Mol Biol Cell 20:3115-24. 2009
  2. ncbi request reprint Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization
    Makoto Kammori
    Department of Gastrointestinal Surgery, The University of Tokyo, Tokyo 113 0033, Japan
    Int J Oncol 20:15-21. 2002
  3. ncbi request reprint Prognostic utility of fluorescence in situ hybridization for determining HER2 gene amplification in breast cancer
    Makoto Kammori
    Department of Surgery, Kanaji Thyroid Hospital, Tokyo 114 0015, Japan
    Oncol Rep 19:651-6. 2008
  4. ncbi request reprint Image in endocrinology: giant mediastinal cystic parathyroid adenoma
    Makoto Kammori
    Division of Metabolic Care Unit and Endocrine Surgery, Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655, Japan
    J Clin Endocrinol Metab 91:1635-6. 2006
  5. ncbi request reprint Demonstration of human telomerase reverse transcriptase (hTERT) in human parathyroid tumours by in situ hybridization with a new oligonucleotide probe
    Makoto Kammori
    Endocrine and Metabolic Unit, Department of Surgery, The University of Tokyo, Japan
    Clin Endocrinol (Oxf) 58:43-8. 2003
  6. ncbi request reprint Forty-three cases of obturator hernia
    Makoto Kammori
    Division of Gastrointestinal Surgery and Metabolic and Endocrine Surgery, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Am J Surg 187:549-52. 2004
  7. ncbi request reprint Expression of human telomerase reverse transcriptase gene and protein, and of estrogen and progesterone receptors, in breast tumors: preliminary data from neo-adjuvant chemotherapy
    Makoto Kammori
    Division of Breast and Endocrine Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Japan
    Int J Oncol 27:1257-63. 2005
  8. ncbi request reprint The pathological findings of vasculitis simultaneously occurring with carcinoma, invasive breast carcinoma in a patient with Behçet's disease
    Makoto Kammori
    Division of Breast and Endocrine Surgery, Department of Surgery, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo, Japan
    Breast Cancer 13:378-81. 2006
  9. ncbi request reprint Clinical application of human telomerase reverse transcriptase gene expression in thyroid follicular tumors by fine-needle aspirations using in situ hybridization
    Makoto Kammori
    Division of Breast Cancer Surgery, Department of Surgery, The University of Tokyo, Japan
    Int J Oncol 22:985-91. 2003
  10. ncbi request reprint Consistent decrease in telomere length in parathyroid tumors but alteration in telomerase activity limited to malignancies: preliminary report
    Makoto Kammori
    Department of Surgery, Endocrine and Metabolic Unit, The University of Tokyo, 3 28 6 Mejirodai, Bunkyo ku, Tokyo 112 8688, Japan
    World J Surg 26:1083-7. 2002

Detail Information

Publications145 found, 100 shown here

  1. pmc Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis
    Masaki Mori
    Division of Gene Therapy Science and Department of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Osaka 565 0871, Japan
    Mol Biol Cell 20:3115-24. 2009
    ..Thus, zyxin reorganizes actin fibers and enhances cell motility in response to TGF-beta1, thereby regulating EMT...
  2. ncbi request reprint Demonstration of human telomerase reverse transcriptase in human colorectal carcinomas by in situ hybridization
    Makoto Kammori
    Department of Gastrointestinal Surgery, The University of Tokyo, Tokyo 113 0033, Japan
    Int J Oncol 20:15-21. 2002
    ..Our findings suggest that ISH-based analysis of hTERT gene expression is superior to both TRAP telomerase activity and hTERT mRNA RT-PCR analysis as a means of determining telomerase status during carcinogenesis...
  3. ncbi request reprint Prognostic utility of fluorescence in situ hybridization for determining HER2 gene amplification in breast cancer
    Makoto Kammori
    Department of Surgery, Kanaji Thyroid Hospital, Tokyo 114 0015, Japan
    Oncol Rep 19:651-6. 2008
    ..Moreover, triple negativity for HER2, ER and PR is a potentially very important prognostic marker...
  4. ncbi request reprint Image in endocrinology: giant mediastinal cystic parathyroid adenoma
    Makoto Kammori
    Division of Metabolic Care Unit and Endocrine Surgery, Department of Cardiothoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655, Japan
    J Clin Endocrinol Metab 91:1635-6. 2006
  5. ncbi request reprint Demonstration of human telomerase reverse transcriptase (hTERT) in human parathyroid tumours by in situ hybridization with a new oligonucleotide probe
    Makoto Kammori
    Endocrine and Metabolic Unit, Department of Surgery, The University of Tokyo, Japan
    Clin Endocrinol (Oxf) 58:43-8. 2003
    ..We have therefore studied hTERT expression in parathyroid tumours...
  6. ncbi request reprint Forty-three cases of obturator hernia
    Makoto Kammori
    Division of Gastrointestinal Surgery and Metabolic and Endocrine Surgery, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Am J Surg 187:549-52. 2004
    ..Obturator hernia is a relatively rare pelvic hernia and usually occurs in elderly, thin, multiparous women. Because symptoms are nonspecific, the diagnosis is often delayed until laparotomy is performed form to treat bowel obstruction...
  7. ncbi request reprint Expression of human telomerase reverse transcriptase gene and protein, and of estrogen and progesterone receptors, in breast tumors: preliminary data from neo-adjuvant chemotherapy
    Makoto Kammori
    Division of Breast and Endocrine Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Japan
    Int J Oncol 27:1257-63. 2005
    ..These results suggest that detection of hTERT protein by ICH can be used to distinguish breast cancers as a potential diagnostic and therapeutic marker...
  8. ncbi request reprint The pathological findings of vasculitis simultaneously occurring with carcinoma, invasive breast carcinoma in a patient with Behçet's disease
    Makoto Kammori
    Division of Breast and Endocrine Surgery, Department of Surgery, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo, Japan
    Breast Cancer 13:378-81. 2006
    ..At 10 months follow-up the patient remains disease free. Malignancies associated with BD are very uncommon. The pathological findings showed small vessel vasculitis and lobulitis of the breast in association with invasive carcinoma...
  9. ncbi request reprint Clinical application of human telomerase reverse transcriptase gene expression in thyroid follicular tumors by fine-needle aspirations using in situ hybridization
    Makoto Kammori
    Division of Breast Cancer Surgery, Department of Surgery, The University of Tokyo, Japan
    Int J Oncol 22:985-91. 2003
    ....
  10. ncbi request reprint Consistent decrease in telomere length in parathyroid tumors but alteration in telomerase activity limited to malignancies: preliminary report
    Makoto Kammori
    Department of Surgery, Endocrine and Metabolic Unit, The University of Tokyo, 3 28 6 Mejirodai, Bunkyo ku, Tokyo 112 8688, Japan
    World J Surg 26:1083-7. 2002
    ..23 +/- 0.86 kbp compared with the 12.61 +/- 0.81 kbp for the 16 age-matched subjects (p = 0.002). The results indicate that telomerase activity and telomere length may reflect the biologic behavior of individual parathyroid lesions...
  11. ncbi request reprint Squamous cell carcinomas of the esophagus arise from a telomere-shortened epithelial field
    Makoto Kammori
    Division of Breast and Endocrine Surgery, Department of Surgery, Nihon University School of Medicine, Tokyo 173 8610, Japan
    Int J Mol Med 20:793-9. 2007
    ..This study furthers our understanding of the mechanism by which telomere shortening and chromosomal instability lead to carcinogenesis and field cancerization in the esophagus...
  12. ncbi request reprint Telomere metabolism and diagnostic demonstration of telomere measurement in the human esophagus for distinguishing benign from malignant tissue by tissue quantitative fluorescence in situ hybridization
    Makoto Kammori
    Department of Breast, Tokyo Metropolitan Tama Cancer Detection Center, Fuchu shi, Tokyo, Japan
    Oncology 71:430-6. 2006
    ..We hypothesized that the very rapid cell proliferation observed in esophageal squamous cell carcinomas might accelerate the telomere shortening and chromosomal instability associated with carcinogenesis...
  13. ncbi request reprint Telomere shortening with aging in human thyroid and parathyroid tissue
    Makoto Kammori
    Endocrine and Metabolic Unit, Department of Surgery, The University of Tokyo, 3 28 6 Mejirodai Bunkyo ku, Tokyo 112 8688, Japan
    Exp Gerontol 37:513-21. 2002
    ....
  14. ncbi request reprint Specific subtelomere loss on chromosome der(11)t(3;11)(q23;q23)x2 in anaplastic thyroid cancer cell line OCUT-1
    Makoto Kammori
    Division of Metabolic Care Unit and Endocrine Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Int J Mol Med 18:9-16. 2006
    ..Our findings suggest that telomere shortening and subtelomere loss are correlated with genetic instability in this anaplastic thyroid carcinoma cell line...
  15. doi request reprint STC2: a predictive marker for lymph node metastasis in esophageal squamous-cell carcinoma
    Yoshiaki Kita
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Ann Surg Oncol 18:261-72. 2011
    ..We sought to identify genes associated with the progression and metastasis of esophageal squamous-cell cancer by comparing the expression profiles of normal, primary cancer, and metastatic cancer cells isolated with laser microdissection...
  16. doi request reprint p53 Mutation status predicts pathological response to chemoradiotherapy in locally advanced esophageal cancer
    Tomoki Makino
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Ann Surg Oncol 17:804-11. 2010
    ..We investigated the correlation between p53 disorders (gene mutation and protein accumulation) and the effects of chemoradiotherapy (CRT)...
  17. doi request reprint Overexpression of forkhead box M1 transcription factor (FOXM1) is a potential prognostic marker and enhances chemoresistance for docetaxel in gastric cancer
    Kaoru Okada
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Ann Surg Oncol 20:1035-43. 2013
    ..Furthermore, we demonstrated correlations between FoxM1 overexpression and drug resistance to chemotherapeutic agents in gastric cancer cells and gastric cancer patients treated with chemotherapy...
  18. doi request reprint Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma
    Takehiko Yokobori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, Beppu 874 0838, Japan
    Int J Oncol 41:253-9. 2012
    ..These genetic alterations of FBXW7 status may provide a prognostic factor for ESCC patients...
  19. doi request reprint Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance
    Yojiro Hashiguchi
    Department of Surgery, National Defense Medical College, 3 2 Namiki, Tokorozawa, Saitama 359 8513, Japan
    Int J Oncol 40:1477-82. 2012
    ....
  20. doi request reprint Neoadjuvant intraperitoneal and systemic chemotherapy for gastric cancer patients with peritoneal dissemination
    Yoshiyuki Fujiwara
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Ann Surg Oncol 18:3726-31. 2011
    ..The present study was designed to assess the feasibility and efficiency of intraperitoneal and intravenous neoadjuvant chemotherapy in gastric cancer patients with peritoneal dissemination...
  21. ncbi request reprint Prediction of the response to chemotherapy in advanced esophageal cancer by gene expression profiling of biopsy samples
    Masaaki Motoori
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
    Int J Oncol 37:1113-20. 2010
    ..This study shows that GEP of pretreatment ESCC biopsy samples has the potential to predict responses to chemotherapy...
  22. ncbi request reprint Pre- and post-therapy nodal status equally affects survival of patients with oesophageal squamous cell carcinoma receiving preoperative chemoradiation
    Hiroshi Miyata
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka 565 0871, Japan
    Oncol Rep 23:1331-7. 2010
    ..Control of systemic metastasis is required, based on pre- and post-therapy LN status...
  23. doi request reprint Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer
    Hisae Iinuma
    Department of Surgery, Teikyo University School of Medicine, 2 11 1, Kaga, Itabashi ku, Tokyo, 173 0003, Japan
    J Clin Oncol 29:1547-55. 2011
    ....
  24. doi request reprint Clinical significance of stanniocalcin 2 as a prognostic marker in gastric cancer
    Takehiko Yokobori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Ann Surg Oncol 17:2601-7. 2010
    ..The clinical significance of Stanniocalcin 2 expression has been observed for several cancers. However, the relationship between Stanniocalcin 2 and clinicopathological factors in gastric cancer has not yet been investigated...
  25. doi request reprint Use of fibrin glue sealant with polyglycolic acid sheets to prevent pancreatic fistula formation after laparoscopic-assisted gastrectomy
    Yuichiro Hiura
    Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Osaka University, 2 2, E2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Surg Today 43:527-33. 2013
    ..The aim of this prospective study was to analyze the usefulness of the local application of fibrin glue sealant (FG) and polyglycolic acid sheets (PAS) in preventing pancreatic fistula formation after gastrectomy...
  26. doi request reprint Larynx-preserving limited resection and free jejunal graft for carcinoma of the cervical esophagus
    Hiroshi Miyata
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka, 565 0871, Japan
    World J Surg 37:551-7. 2013
    ..There is no generally accepted treatment strategy for cervical cancer. The aim of this study was to evaluate the safety and efficacy of larynx-preserving limited resection with free jejunal graft for cervical esophageal cancer...
  27. doi request reprint Role of the hypoxia-related gene, JMJD1A, in hepatocellular carcinoma: clinical impact on recurrence after hepatic resection
    Daisaku Yamada
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Ann Surg Oncol 19:S355-64. 2012
    ..One function of this demethylase is to amplify hypoxia-inducible gene expression. We hypothesized that the demethylase would be a significant marker of hepatocellular carcinoma...
  28. doi request reprint Intraperitoneal docetaxel combined with S-1 for advanced gastric cancer with peritoneal dissemination
    Yoshiyuki Fujiwara
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    J Surg Oncol 105:38-42. 2012
    ..This study evaluated the benefits of this combination chemotherapy and subsequent surgery...
  29. doi request reprint p53 genotype predicts response to chemotherapy in patients with squamous cell carcinoma of the esophagus
    Makoto Yamasaki
    Departments of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Ann Surg Oncol 17:634-42. 2010
    ..Predicting the response to chemotherapy would allow significant optimization of cancer treatment...
  30. ncbi request reprint Clinicopathologic and biological significance of kallikrein 6 overexpression in human gastric cancer
    Hisashi Nagahara
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Tsurumihara, Beppu, Japan
    Clin Cancer Res 11:6800-6. 2005
    ..Herein, we investigated the clinicopathologic and biological significance of KLK6 gene expression in human gastric cancer...
  31. pmc Combination of interferon-alpha and 5-fluorouracil inhibits endothelial cell growth directly and by regulation of angiogenic factors released by tumor cells
    Hiroshi Wada
    Department of Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka E 2, Suita 565 0871 Osaka, Japan
    BMC Cancer 9:361. 2009
    ....
  32. ncbi request reprint [A case of complete response to S-1 therapy for multiple pulmonary recurrences of hepatocellular carcinoma after hepatic resection]
    Akira Tomokuni
    Department of Surgery, Graduate School of Medicine, Osaka University
    Gan To Kagaku Ryoho 36:2383-5. 2009
    ..This case illustrates that S-1 may be an effective treatment for HCC with extrahepatic metastasis...
  33. ncbi request reprint Tumor-derived tenascin-C promotes the epithelial-mesenchymal transition in colorectal cancer cells
    Yusuke Takahashi
    Department of Surgery, Beppu Hospital, Kyushu University, 4546 Tsurumihara, Beppu 874 0838, Japan
    Anticancer Res 33:1927-34. 2013
    ..Recently, however, the significance of tumor-derived TNC in initiation of cancer metastasis was disclosed. We investigated the clinical significance of cancer-derived TNC in colorectal cancer (CRC) cases...
  34. doi request reprint Oncofetal protein, IMP-3, a potential marker for prediction of postoperative peritoneal dissemination in gastric adenocarcinoma
    Kaoru Okada
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    J Surg Oncol 105:780-5. 2012
    ....
  35. ncbi request reprint [A long-term survival case of pancreatic cancer with hepatic metastasis after pancreaticoduodenectomy successfully treated by s-1 and gemcitabine combination chemotherapy]
    Hiromitsu Hoshino
    Department of Surgery, Graduate School of Medicine, Osaka University, and Osaka National Hospital, National Hospital Organization
    Gan To Kagaku Ryoho 36:2419-21. 2009
    ..S-1 and gemcitabine combination therapy is not only effective but also well tolerated and safe. This combination therapy should be considered one of selective choices for advanced or metastatic pancreatic cancer...
  36. ncbi request reprint [A long-term survival case of hepatocellular carcinoma with lymph node metastasis on the posterior surface of the pancreas head and portal vein tumor thrombus successfully treated with hepatopancreatoduodenectomy and adjuvant interferon-alpha and 5-fluoro
    Yoshito Tomimaru
    Department of Surgery, Graduate School of Medicine, Osaka University
    Gan To Kagaku Ryoho 36:2389-91. 2009
    ....
  37. doi request reprint Comparison of Billroth I and Roux-en-Y reconstruction after distal gastrectomy for gastric cancer: one-year postoperative effects assessed by a multi-institutional RCT
    Motohiro Hirao
    Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan
    Ann Surg Oncol 20:1591-7. 2013
    ..This randomized, controlled trial evaluated the clinical efficacy of Billroth I (BI) and Roux-en-Y (RY) reconstruction at 1 year after distal gastrectomy for gastric cancer...
  38. doi request reprint Effects of ghrelin administration during chemotherapy with advanced esophageal cancer patients: a prospective, randomized, placebo-controlled phase 2 study
    Yuichiro Hiura
    Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Cancer 118:4785-94. 2012
    ..The authors of this report conducted a prospective, randomized phase 2 trial to evaluate the effects of exogenous ghrelin during cisplatin-based chemotherapy...
  39. doi request reprint Randomized study of clinical effect of enteral nutrition support during neoadjuvant chemotherapy on chemotherapy-related toxicity in patients with esophageal cancer
    Hiroshi Miyata
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Clin Nutr 31:330-6. 2012
    ..Enteral nutrition (EN) is provided for patients with cancer. However, Little is known about the clinical efficacy of EN support during chemotherapy in patients with cancer...
  40. pmc Assessment of stanniocalcin-1 as a prognostic marker in human esophageal squamous cell carcinoma
    Mitsuhiro Shirakawa
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
    Oncol Rep 27:940-6. 2012
    ..STC1 is a potentially useful biomarker for ESCC treatment...
  41. doi request reprint Tyrosine kinase inhibitor PTK/ZK enhances the antitumor effects of interferon-α/5-fluorouracil therapy for hepatocellular carcinoma cells
    Masahiro Murakami
    Department of Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Ann Surg Oncol 18:589-96. 2011
    ..In this study, we showed the VEGF-related effects of IFN/5-FU therapy using VEGF-receptor (VEGFR) selective inhibitor, PTK787/ZK222584 (PTK/ZK), in HCC cells...
  42. doi request reprint Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer: in vivo identification from hypoxic tumor cells
    Mamoru Uemura
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Faculty of Medicine, Osaka University, Osaka, Japan
    Clin Cancer Res 16:4636-46. 2010
    ..This study aimed to identify novel hypoxia-inducible and prognostic markers in vivo from hypoxic tumor cells...
  43. doi request reprint CD133+CD44+ population efficiently enriches colon cancer initiating cells
    Naotsugu Haraguchi
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, 565 0871, Japan
    Ann Surg Oncol 15:2927-33. 2008
    ..In this study, we evaluated the tumorigenicity of each population of human colon cancer divided by CD133 and CD44 using non-obese diabetic/severe combined immunodeficient (NOD/SCID) mice...
  44. doi request reprint Gene expression profile prospectively predicts peritoneal relapse after curative surgery of gastric cancer
    Atsushi Takeno
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Ann Surg Oncol 17:1033-42. 2010
    ..Clinicopathological findings are sometimes inadequate for predicting peritoneal relapse. The aim of this study was to identify patients at high risk of peritoneal relapse in a prospective study based on molecular prediction...
  45. ncbi request reprint [A case of successful multimodal treatment for combined hepatocellular and cholangiocarcinoma with portal venous tumor thrombus]
    Hisanori Hatano
    Department of Surgery, Graduate School of Medicine, Osaka University
    Gan To Kagaku Ryoho 36:2374-6. 2009
    ..Thereafter, sustained partial remission was achieved. In case of combined hepatocellular and cholangiocarcinoma, we need to create a treatment strategy against characteristics of both components...
  46. doi request reprint Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer
    Toru Masuzawa
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Int J Oncol 41:1297-304. 2012
    ..Thus, cancer vaccination combined with standard chemotherapy warrants further analysis as a promising strategy for the treatment of advanced cancer...
  47. doi request reprint Clinical significance of surgery for gastric submucosal tumours with size enlargement during watchful waiting period
    Yasuhiro Miyazaki
    Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Eur J Cancer 49:2681-8. 2013
    ..The true impact of surgery for small, asymptomatic and biopsy-negative gastric submucosal tumours (SMTs) with size enlargement during 'watchful waiting' period has not been fully understood...
  48. doi request reprint Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis
    Takehiko Yokobori
    Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan
    Cancer Res 73:2059-69. 2013
    ..07; 95% CI = 1.50-11.57) and Dukes C (HR = 2.57; 95% CI = 1.42-4.63). PLS3 is a novel marker for metastatic CRC cells, and it possesses significant prognostic value...
  49. doi request reprint Role of crosstalk between interleukin-6 and transforming growth factor-beta 1 in epithelial-mesenchymal transition and chemoresistance in biliary tract cancer
    Daisaku Yamada
    Department of Surgery, Graduate School of Medicine, Osaka University, Yamadaoka 2 2 E2, Suita, Osaka 565 0871, Japan
    Eur J Cancer 49:1725-40. 2013
    ....
  50. doi request reprint Reduced plasma ghrelin levels on day 1 after esophagectomy: a new predictor of prolonged systemic inflammatory response syndrome
    Kazuyoshi Yamamoto
    Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Osaka University, 2 2, E2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Surg Today 43:48-54. 2013
    ..The aim of this study was to investigate the relationship between serial changes in plasma ghrelin concentrations and the postoperative clinical course after esophagectomy...
  51. doi request reprint Fibrin sealant with PGA felt for prevention of bile leakage after liver resection
    Shogo Kobayashi
    Department of Surgery, Osaka University, Osaka, Japan
    Hepatogastroenterology 59:2564-8. 2012
    ..We performed preliminary evaluation of fibrin sealing combined with PGA felt (PGA-FS) as hemostat and to prevent biliary leakage, in comparison with the conventional fibrin-coated collagen fleece (FC-CF), retrospectively...
  52. ncbi request reprint The features of late local recurrences following curative surgery for rectal cancer
    Mamoru Uemura
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Hepatogastroenterology 59:1800-3. 2012
    ..Rectal cancers are characterized by high incidence of local recurrence after curative surgery, in some cases it occurs after 5 years. To determine the features of late locally recurrent rectal cancer (LRRC) is important for its management...
  53. doi request reprint Equivalent outcomes after anatomical and non-anatomical resection of small hepatocellular carcinoma in patients with preserved liver function
    Yoshito Tomimaru
    Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Dig Dis Sci 57:1942-8. 2012
    ..Although anatomical resection (AR) is considered better than non-anatomical resection (NAR) for the treatment for hepatocellular carcinoma (HCC), there is only limited evidence in support of this argument...
  54. doi request reprint Once-daily prolonged-release tacrolimus in de novo liver transplantation: a single center cohort study
    Shigeru Marubashi
    Department of Surgery, Osaka University, Osaka, Japan
    Hepatogastroenterology 59:1184-8. 2012
    ..The feasibility of oral administration of once-daily prolonged-release tacrolimus (TAC-PR) in de novo liver transplantation is not clear and therefore was investigated further...
  55. doi request reprint Increased immunogenicity of tumor-associated antigen, mucin 1, engineered to express alpha-gal epitopes: a novel approach to immunotherapy in pancreatic cancer
    Takashi Deguchi
    Department of Surgery, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Cancer Res 70:5259-69. 2010
    ..The results suggested that vaccination using cells engineered to express alpha-gal epitopes is a novel strategy for treatment of pancreatic cancer...
  56. ncbi request reprint Induction chemotherapy with docetaxel, 5-FU and CDDP (DFP) for advanced gastric cancer
    Kazuyoshi Yamamoto
    Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Osaka University, 2 2, E2, Yamadaoka, Suita, Osaka 565 0871, Japan
    Anticancer Res 29:4211-5. 2009
    ..The aim of this study was to evaluate the feasibility and efficacy of modified triplet chemotherapy with docetaxel, 5-fluorouracil and cisplatin as induction chemotherapy for advanced gastric cancer (AGC)...
  57. doi request reprint Steroid-free living donor liver transplantation in adults: impact on hepatitis C recurrence
    Shigeru Marubashi
    Department of Surgery, Osaka University, Graduate School of Medicine, Suita, Osaka, Japan
    Clin Transplant 23:904-13. 2009
    ..We aimed to clarify the impact of steroid-free immunosuppression on post-operative HCV recurrence after living donor liver transplantation (LDLT)...
  58. ncbi request reprint Utility of 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography in differential diagnosis of benign and malignant intraductal papillary-mucinous neoplasm of the pancreas
    Yoshito Tomimaru
    Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Oncol Rep 24:613-20. 2010
    ..5 offered the best diagnosis of malignant IPMN. These results suggest that FDG-PET is useful for differentiation of malignant IPMN of the pancreas, and that it should be performed in combination with other conventional imaging modalities...
  59. pmc CD13 is a therapeutic target in human liver cancer stem cells
    Naotsugu Haraguchi
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    J Clin Invest 120:3326-39. 2010
    ..Therefore, combining a CD13 inhibitor with a ROS-inducing chemo/radiation therapy may improve the treatment of liver cancer...
  60. doi request reprint A thick pancreas is a risk factor for pancreatic fistula after a distal pancreatectomy: selection of the closure technique according to the thickness
    Hidetoshi Eguchi
    Department of Surgery, Graduate School of Medicine, Osaka University, Japan
    Dig Surg 28:50-6. 2011
    ..Hand-sewn closures or stapler closures of the pancreatic remnant after a distal pancreatectomy have commonly been employed; however, the choice of technique in each patient depending on their clinical characteristics has not been discussed...
  61. doi request reprint Multicenter phase I/II study of docetaxel, cisplatin and fluorouracil combination chemotherapy in patients with advanced or recurrent squamous cell carcinoma of the esophagus
    Makoto Yamasaki
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 E2 Yamadaoka, Suita, Osaka, Japan
    Oncology 80:307-13. 2011
    ..To this end, we conducted a multicenter phase I/II trial of docetaxel, cisplatin, and fluorouracil (DCF) combination chemotherapy for ESCC...
  62. ncbi request reprint Parthenolide, an NF-κB inhibitor, suppresses tumor growth and enhances response to chemotherapy in gastric cancer
    Itsuro Sohma
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
    Cancer Genomics Proteomics 8:39-47. 2011
    ..This study evaluated the sesquiterpene lactone parthenolide, an inhibitor of transcription factor nuclear factor-kappaB (NF-κB), in the treatment of gastric cancer in vitro and in vivo...
  63. doi request reprint Treatment of borderline cases for curative resection of biliary tract cancer
    Shogo Kobayashi
    Department of Surgery, Osaka University, Suita, Osaka, Japan
    J Surg Oncol 104:499-503. 2011
    ..To dissect the high rate of non-curative resection associated with biliary tract cancer, we compared the outcome of non-curative resection with that of inoperable cancer in patients referred for surgery...
  64. ncbi request reprint Overexpression of MT1-MMP is insufficient to increase experimental liver metastasis of human colon cancer cells
    Hirofumi Yamamoto
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamada oka, Osaka 565 0871, Japan
    Int J Mol Med 22:757-61. 2008
    ..Our findings indicated that conditional MT1-MMP overexpression was insufficient to increase experimental liver metastasis, suggesting a more complicated mechanism may be involved in the activation and regulation of MMPs cascades in vivo...
  65. doi request reprint Increased risk for CRC in diabetic patients with the nonrisk allele of SNPs at 8q24
    Shinya Ishimaru
    Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan
    Ann Surg Oncol 19:2853-8. 2012
    ..Colorectal cancer (CRC) oncogenesis was considered to be determined by interactions between genetic and environmental factors. Specific interacting factors that influence CRC morbidity have yet to be fully investigated...
  66. doi request reprint Laparoscopic intragastric surgery revisited: its role for submucosal tumors adjacent to the esophagogastric junction
    Johji Hara
    Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    Surg Laparosc Endosc Percutan Tech 22:251-4. 2012
    ..In this study, we describe our clinical experience with laparoscopic intragastric surgery (LIGS) and discuss its role for gastric SMTs adjacent to EGJ...
  67. doi request reprint Significance of alanine aminopeptidase N (APN) in bile in the diagnosis of acute cellular rejection after liver transplantation
    Chiwan Kim
    Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    J Surg Res 175:138-48. 2012
    ..The aim of this study was to find novel protein markers in bile for the diagnosis of acute cellular rejection (ACR) after liver transplantation...
  68. doi request reprint PLOD2 induced under hypoxia is a novel prognostic factor for hepatocellular carcinoma after curative resection
    Takehiro Noda
    The Department of Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Liver Int 32:110-8. 2012
    ..Hypoxia also stimulates expression of procollagen-lysine, 2-oxoglutarate 5-dioxygenase (PLOD) genes via the HIF-1 pathway...
  69. doi request reprint Risk factors for postoperative delirium in elderly patients with colorectal cancer
    Mitsuyoshi Tei
    Department of Surgery, Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita City, Osaka, Japan
    Surg Endosc 24:2135-9. 2010
    ..The aim of this retrospective study is to examine risk factors for postoperative delirium in elderly patients with colorectal cancer...
  70. doi request reprint Multimodal treatment for resectable esophageal cancer
    Hiroshi Miyata
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Gen Thorac Cardiovasc Surg 59:461-6. 2011
    ..However, we also must compare the survival benefits of preoperative chemotherapy with preoperative chemoradiotherapy...
  71. pmc Fresh frozen plasma transfusion does not affect outcomes following hepatic resection for hepatocellular carcinoma
    Yoshito Tomimaru
    Department of Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka E 2, Suita, 565 0871 Osaka, Japan
    World J Gastroenterol 16:5603-10. 2010
    ..To investigate whether fresh frozen plasma (FFP) transfusion affects outcomes following hepatic resection for hepatocellular carcinoma (HCC) in terms of liver function, postoperative complications and cancer prognosis...
  72. doi request reprint A suspected [18F]fluorodeoxyglucose positron emission tomography-negative metastatic lymph node successfully diagnosed by laparoscopic staging in esophageal cancer: report of two cases
    Atsushi Takeno
    Department of Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka 565 0871, Japan
    Surg Today 39:888-91. 2009
    ..This technique can be recommended for patients with esophageal cancer in whom the diagnosis of enlarged lymph node cannot be confirmed by preoperative imaging...
  73. doi request reprint Prognostic value of endoscopic biopsy findings after induction chemoradiotherapy with and without surgery for esophageal cancer
    Hiroshi Miyata
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka, Suita, Osaka, Japan
    Ann Surg 253:279-84. 2011
    ..To investigate the value of endoscopic biopsy in predicting the clinicopathological response and survival in patients with esophageal cancers who received chemoradiotherapy (CRT) alone or CRT followed by surgery...
  74. ncbi request reprint Feasibility study of S-1 and intraperitoneal docetaxel combination chemotherapy for gastric cancer with peritoneal dissemination
    Yoshiyuki Fujiwara
    Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
    Anticancer Res 30:1335-9. 2010
    ..Here we performed a dose-escalation study of intraperitoneal docetaxel (DTX) combined with S-1 to determine the maximum-tolerated dose (MTD) and recommended dose (RD) in gastric cancer with peritoneal dissemination...
  75. doi request reprint Synergistic antitumor effect of interferon-ß with gemcitabine in interferon-α-non-responsive pancreatic cancer cells
    Yoshito Tomimaru
    Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    Int J Oncol 38:1237-43. 2011
    ..In conclusion, our results indicated that the growth-inhibitory effect of IFN-ß with gemcitabine was synergistic not only in pancreatic cancer cells with strong expression of IFNAR2, but also in those with weak expression of IFNAR2...
  76. doi request reprint Utility of response evaluation to neo-adjuvant chemotherapy by (18)F-fluorodeoxyglucose-positron emission tomography in locally advanced esophageal squamous cell carcinoma
    Tomoki Makino
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Surgery 148:908-18. 2010
    ..Neoadjuvant chemotherapy (NACT) has been frequently used for locally advanced esophageal squamous cell cancer (ESCC). It is therefore important to establish criteria for evaluating the response to NACT based on survival analysis...
  77. doi request reprint Clinical significance of alpha-fetoprotein mRNA in peripheral blood in liver resection for hepatocellular carcinoma
    Shigeru Marubashi
    Department of Surgery, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    Ann Surg Oncol 18:2200-9. 2011
    ..However, its interpretation and clinical significance remains to be determined. This study was designed to evaluate the clinical significance of detecting AFP mRNA positive cells in peripheral blood...
  78. ncbi request reprint Hypoxia-inducible adrenomedullin in colorectal cancer
    Mamoru Uemura
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamada oka, Suita City, Osaka 565 0871, Japan
    Anticancer Res 31:507-14. 2011
    ..Among them, expression of adrenomedullin (ADM) was an interesting target because it is highly induced by hypoxia...
  79. ncbi request reprint A safe protocol of intermittent hilar vascular clamping for hepatic resection in cirrhosis
    Hiroaki Nagano
    Department of Surgery, Graduate School of Medicine, Osaka University, 2 2 Yamadaoka E 2, Suita 565 0871 Osaka, Japan
    Hepatogastroenterology 56:1439-44. 2009
    ..Postoperative liver function was assessed at days 1, 3 and 5...
  80. doi request reprint Long-term outcome of combined interferon-α and 5-fluorouracil treatment for advanced hepatocellular carcinoma with major portal vein thrombosis
    Hiroaki Nagano
    Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    Oncology 80:63-9. 2011
    ....
  81. doi request reprint Exploration of potential genomic portraits associated with intrahepatic recurrence in human hepatocellular carcinoma
    Nobuyoshi Kittaka
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Ann Surg Oncol 17:3145-54. 2010
    ..Here we examine the association between biological signals and intrahepatic recurrence using global gene expression profiles and powerful analytical methods...
  82. doi request reprint Postoperative complications in elderly patients with colorectal cancer: comparison of open and laparoscopic surgical procedures
    Mitsuyoshi Tei
    Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
    Surg Laparosc Endosc Percutan Tech 19:488-92. 2009
    ..The aim of this study was to examine preoperative evaluation for selecting operative procedure in elderly patients with colorectal cancer...
  83. doi request reprint Minimally invasive esophagectomy for esophageal cancer: comparative analysis of open and hand-assisted laparoscopic abdominal lymphadenectomy with gastric conduit reconstruction
    Makoto Yamasaki
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan
    J Surg Oncol 104:623-8. 2011
    ..Esophagectomy for esophageal cancer is an invasive procedure. Minimally invasive approaches such as hand-assisted laparoscopic surgery (HALS) might reduce surgical stress and improve postoperative course...
  84. doi request reprint Biliary reconstruction in living donor liver transplantation: technical invention and risk factor analysis for anastomotic stricture
    Shigeru Marubashi
    Department of Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Transplantation 88:1123-30. 2009
    ..The objectives of this study were to investigate the outcome of biliary reconstruction using "open-up" anastomotic technique and to clarify the risk factors for biliary stricture after LDLT...
  85. ncbi request reprint Clinicopathologic and prognostic values of apolipoprotein D alterations in hepatocellular carcinoma
    Tohru Utsunomiya
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Int J Cancer 116:105-9. 2005
    ..Apo D may be a novel tumor suppressor gene of HCC, and its expression status may be a useful biomarker for predicting the patient outcome...
  86. doi request reprint The search for cancer stem cells in hepatocellular carcinoma
    Yukio Kamohara
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Surgery 144:119-24. 2008
    ..Because most stem cells reside in the G0 phase of the cell cycle, G0 cells were isolated, and the relationship between SP cells and G0 cells was investigated to clarify the biological characteristics of G0 cells...
  87. ncbi request reprint [A case of locally advanced pancreatic cancer with superior membrane artery invasion successfully resected after gemcitabine-based chemoradiotherapy]
    Yoshiaki Ohmura
    Department of Surgery, Graduate School of Medicine, Osaka University, and Osaka National Hospital, National Hospital Organization
    Gan To Kagaku Ryoho 36:2428-9. 2009
    ..Adjuvant chemotherapy with 6 courses of GEM was also performed. The patient has no recurrence, suggesting the efficacy of GEM-based CRT for locally advanced borderline unresectable pancreatic cancer...
  88. doi request reprint Salvage esophagectomy after definitive chemoradiotherapy for thoracic esophageal cancer
    Hiroshi Miyata
    Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Osaka 565 0871, Japan
    J Surg Oncol 100:442-6. 2009
    ..The aim of this study was to compare the outcome of salvage esophagectomy after high-dose definitive CRT with neoadjuvant CRT...
  89. doi request reprint A single-incision laparoscopic hepatectomy for hepatocellular carcinoma: initial experience in a Japanese patient
    Shogo Kobayashi
    Department of Surgery, Osaka University, Yamadaoka 2 2, Suita City, Osaka, Japan
    Minim Invasive Ther Allied Technol 19:367-71. 2010
    ..Various aspects of the procedure were not different from TLS. SILH is a safe procedure with several advantages. The procedure is promising as minimally invasive liver surgery...
  90. ncbi request reprint INI-1, a partner gene of ALL-1, is highly conserved in human acute leukemia
    Koshi Mimori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, Beppu 874 0838, Japan
    Oncol Rep 10:551-3. 2003
    ..In conclusion, INI-1, a partner gene for ALL-1, is considered to be highly conserved in acute leukemia cases...
  91. doi request reprint A Japanese Lung Cancer Registry study: prognosis of 13,010 resected lung cancers
    Hisao Asamura
    Division of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan
    J Thorac Oncol 3:46-52. 2008
    ..The validation of tumor, node, metastasis staging system in terms of prognosis is an indispensable part of establishing a better staging system in lung cancer...
  92. ncbi request reprint Coexpression of matrix metalloproteinase-7 (MMP-7) and epidermal growth factor (EGF) receptor in colorectal cancer: an EGF receptor tyrosine kinase inhibitor is effective against MMP-7-expressing cancer cells
    Koshi Mimori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Clin Cancer Res 10:8243-9. 2004
    ..Recent studies focus on diverse roles of MMP-7, other than as a protease, during cancer progression. MMP-7 activates the epidermal growth factor (EGF) receptor by releasing an EGF ligand, tumor growth factor (TGF)-alpha...
  93. ncbi request reprint Involvement of gamma-secretase in postnatal angiogenesis
    Hiroki Hayashi
    Division of Gene Therapy Science, Graduate School of Medicine, Osaka University, 2 2 Yamada oka, Suita, Osaka 565 0871, Japan
    Biochem Biophys Res Commun 363:584-90. 2007
    ....
  94. ncbi request reprint Expression of the TRAG-3 gene in human esophageal cancer: the frequent synchronous expression of MAGE-3 gene
    Mitsuhiko Ohta
    Department of Surgery, Medical Institute of Bioregulation Kyushu University, 4546 Tsurumihara, Beppu 874 0838, Japan
    Oncol Rep 15:1529-32. 2006
    ..05). As the TRAG-3 gene is located on Xq28, which is the same locus as the MAGE gene family, we found a frequent synchronous expression pattern with TRAG-3 and MAGE-3 in esophageal cancer...
  95. ncbi request reprint Microsatellite instability is often observed in esophageal carcinoma patients with allelic loss in the FHIT/FRA3B locus
    Koshi Mimori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Tsurumihara 4546, Beppu 874 0838, Japan
    Oncology 64:275-9. 2003
    ..We concluded that MSI is significantly related to the allelic loss in the FHIT/FRA3B region, but Msh2 might be unrelated to the progression or oncogenic process in esophageal cancer...
  96. ncbi request reprint Synergically increased expression of CD36, CLA-1 and CD68, but not of SR-A and LOX-1, with the progression to foam cells from macrophages
    Kayo Tsukamoto
    Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan
    J Atheroscler Thromb 9:57-64. 2002
    ..We thus propose that CD36, CLA-1 and CD68, but not SR-A and LOX-1, may play crucial roles in the progression of macrophages to foam cells, which is a key step for the initiation of atherosclerosis...
  97. ncbi request reprint A single-nucleotide polymorphism of SMARCB1 in human breast cancers
    Koshi Mimori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Genomics 80:254-8. 2002
    ..We found a nucleotide change at codon 152 of SMARCB1 that may alter the amount of immunoprecipitated cMYC protein, but we finally determined that SMARCB1 is highly conserved in human solid carcinomas...
  98. doi request reprint p53-Altered FBXW7 expression determines poor prognosis in gastric cancer cases
    Takehiko Yokobori
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Cancer Res 69:3788-94. 2009
    ..0033). In conclusion, we showed a role for p53 in the transcriptional regulation of FBXW7 expression in clinical gastric cancer cases and showed that disruption of both p53 and FBXW7 contributes to poor prognosis...
  99. doi request reprint Prolonged survival of pig islets xenograft by adenovirus-mediated expression of either the membrane-bound human FasL or the human decoy Fas antigen gene
    Koichi Kawamoto
    Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    Xenotransplantation 15:333-43. 2008
    ..In this study, we assessed the cytoprotective effects of these molecules for pig islets both in vitro and in vivo...
  100. doi request reprint PDGF-BB is a novel prognostic factor in colorectal cancer
    Yoshito Nakamura
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumibaru, Beppu 874 0838, Japan
    Ann Surg Oncol 15:2129-36. 2008
    ..However, its expression in colorectal cancer has not been studied. We thus investigated the clinicopathological and biological significance of PDGF-BB gene expression in human colorectal cancer...
  101. ncbi request reprint Global analysis of altered gene expressions during the process of esophageal squamous cell carcinogenesis in the rat: a study combined with a laser microdissection and a cDNA microarray
    Koujiro Nishida
    Department of Surgery, Medical Institute of Bioregulation, Kyushu University, Tsurumihara, Beppu, Japan
    Cancer Res 65:401-9. 2005
    ....