Hiroyuki Momota

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi Intravascular lymphoma of the central nervous system presenting as multiple cerebral infarctions
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan
    Nagoya J Med Sci 74:353-8. 2012
  2. doi p53 abnormality and tumor invasion in patients with malignant astrocytoma
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Brain Tumor Pathol 27:95-101. 2010
  3. doi Mouse models of CNS embryonal tumors
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Brain Tumor Pathol 26:43-50. 2009
  4. doi Rhabdoid glioblastoma in a child: case report and literature review
    Hiroyuki Momota
    Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Brain Tumor Pathol 28:65-70. 2011
  5. doi Prognostic value of immunohistochemical profile and response to high-dose methotrexate therapy in primary CNS lymphoma
    Hiroyuki Momota
    Department of Neurosurgery, Nagoya University, Graduate School of Medicine, 65, Tsurumai cho, Showa Ku, Nagoya 466 8550, Japan
    J Neurooncol 98:341-8. 2010
  6. doi Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan
    Pediatr Blood Cancer 55:577-9. 2010
  7. pmc Secondary hematological malignancies associated with temozolomide in patients with glioma
    Hiroyuki Momota
    Corresponding Author Yoshitaka Narita, PhD, MD, Department of Neurosurgery and Neuro Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Neuro Oncol 15:1445-50. 2013
  8. doi Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomas
    Kazuya Motomura
    Department of Neurosurgery, Nagoya University School of Medicine, Japan
    Cancer Sci 103:1871-9. 2012
  9. doi Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy
    Kazuya Motomura
    Department of Neurosurgery, Nagoya University School of Medicine, Nagoya, Japan
    Leuk Lymphoma 52:2069-75. 2011
  10. doi A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models
    Kenichiro Iwami
    Department of Neurosurgery, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    J Neurosurg 116:630-5. 2012

Collaborators

Detail Information

Publications15

  1. ncbi Intravascular lymphoma of the central nervous system presenting as multiple cerebral infarctions
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan
    Nagoya J Med Sci 74:353-8. 2012
    ..Here, we present a case of CNS IVL, with its radiographic and pathologic features and treatment with high-dose methotrexate chemotherapy...
  2. doi p53 abnormality and tumor invasion in patients with malignant astrocytoma
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Brain Tumor Pathol 27:95-101. 2010
    ..As diffuse and multiple features on imaging modalities represent invasive characteristics of the tumors, p53 abnormalities may affect the invasive and aggressive nature of malignant astrocytomas...
  3. doi Mouse models of CNS embryonal tumors
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
    Brain Tumor Pathol 26:43-50. 2009
    ..These data provide insight into the biology and classification of CNS embryonal tumors...
  4. doi Rhabdoid glioblastoma in a child: case report and literature review
    Hiroyuki Momota
    Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
    Brain Tumor Pathol 28:65-70. 2011
    ..Genetic studies confirmed no loss of the INI1 gene and identified hemizygous deletion of the CDKN2A gene. We review reported cases of rhabdoid glioblastoma and summarize the clinical, radiological, and histological features...
  5. doi Prognostic value of immunohistochemical profile and response to high-dose methotrexate therapy in primary CNS lymphoma
    Hiroyuki Momota
    Department of Neurosurgery, Nagoya University, Graduate School of Medicine, 65, Tsurumai cho, Showa Ku, Nagoya 466 8550, Japan
    J Neurooncol 98:341-8. 2010
    ..However, the response itself was a significant predictor for both progression-free survival (P < 0.001) and overall survival (P = 0.003). Further investigation is needed to assess BCL-6 as a potential prognostic factor in PCNSL...
  6. doi Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutation
    Hiroyuki Momota
    Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan
    Pediatr Blood Cancer 55:577-9. 2010
    ..We demonstrate a rare case of TMZ-related ALL in a child with glioma possibly associated with a germline TP53 mutation...
  7. pmc Secondary hematological malignancies associated with temozolomide in patients with glioma
    Hiroyuki Momota
    Corresponding Author Yoshitaka Narita, PhD, MD, Department of Neurosurgery and Neuro Oncology, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    Neuro Oncol 15:1445-50. 2013
    ....
  8. doi Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomas
    Kazuya Motomura
    Department of Neurosurgery, Nagoya University School of Medicine, Japan
    Cancer Sci 103:1871-9. 2012
    ..This is the first study to establish a subclassification of GBM on the basis of immunohistochemical analysis. Our study will shed light on personalized therapies that might be feasible in daily neuropathological practice...
  9. doi Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy
    Kazuya Motomura
    Department of Neurosurgery, Nagoya University School of Medicine, Nagoya, Japan
    Leuk Lymphoma 52:2069-75. 2011
    ..Our study investigated the efficacy of DeVIC chemotherapy in PCNSL patients, and found it to result in favorable survival outcomes in these patients, thus warranting further investigation of it as a therapeutic measure against PCNSL...
  10. doi A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse models
    Kenichiro Iwami
    Department of Neurosurgery, Nagoya University, Graduate School of Medicine, Nagoya, Japan
    J Neurosurg 116:630-5. 2012
    ..The aim of this study was to establish a simple and accurate method for intracranial injection of cells or other materials into mice...
  11. ncbi [A survey of neurosurgeons' policies and attitudes regarding the disclosure of a diagnosis of glioma and the decision to pursue end-of-life care in glioma patients]
    Yoshitaka Narita
    Neurosurgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
    No Shinkei Geka 37:973-81. 2009
    ..We surveyed neurosurgeons in Japan with regard to their policies and attitudes concerning the disclosure of a diagnosis of glioma and their thoughts on the end-of-life care of glioma patients...
  12. pmc The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma
    Fumiharu Ohka
    Department of Neurosurgery, Nagoya University School of Medicine, Nagoya, Japan
    PLoS ONE 6:e23332. 2011
    ..As a global DNA methylation marker, LINE-1 may be a promising marker in gliomas...
  13. doi Glioblastoma simultaneously present with adjacent meningioma: case report and review of the literature
    Kengo Suzuki
    Department of Neurosurgery, Sapporo Medical University School of Medicine, South 1, West 16, Chuo Ku, Sapporo 060 8543, Japan
    J Neurooncol 99:147-53. 2010
    ..The PDGF-mediated paracrine system may induce one tumor from another...
  14. ncbi Immunohistochemical analysis of the p53 family members in human craniopharyngiomas
    Hiroyuki Momota
    Department of Pathology, Sapporo Medical University School of Medicine, South 1, West 17, Chuo Ku, Sapporo 060 8556, Japan
    Brain Tumor Pathol 20:73-7. 2003
    ....
  15. ncbi p73 is expressed in human thymic epithelial cells
    Shingo Ichimiya
    Department of Pathology, Sapporo Medical University School of Medicine, South 1 West 17, Chuo Ku, Sapporo 060 8556, Japan
    J Histochem Cytochem 50:455-62. 2002
    ..Because p73 has the capacity to be a transactivator like p53, it may contribute to T-cell development in the context of TEC biology as regulated in the cell cycle and apoptosis...