Research Topics
Species | Hiroyuki MomotaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Detail Information
Publications
Intravascular lymphoma of the central nervous system presenting as multiple cerebral infarctionsHiroyuki Momota
Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan
Nagoya J Med Sci 74:353-8. 2012..Here, we present a case of CNS IVL, with its radiographic and pathologic features and treatment with high-dose methotrexate chemotherapy...
Rhabdoid glioblastoma in a child: case report and literature reviewHiroyuki Momota
Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya 466 8550, Japan
Brain Tumor Pathol 28:65-70. 2011..Genetic studies confirmed no loss of the INI1 gene and identified hemizygous deletion of the CDKN2A gene. We review reported cases of rhabdoid glioblastoma and summarize the clinical, radiological, and histological features...- p53 abnormality and tumor invasion in patients with malignant astrocytomaHiroyuki Momota
Neurosurgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Brain Tumor Pathol 27:95-101. 2010..As diffuse and multiple features on imaging modalities represent invasive characteristics of the tumors, p53 abnormalities may affect the invasive and aggressive nature of malignant astrocytomas... - Acute lymphoblastic leukemia after temozolomide treatment for anaplastic astrocytoma in a child with a germline TP53 mutationHiroyuki Momota
Neurosurgery Division, National Cancer Center Hospital, Tokyo, Japan
Pediatr Blood Cancer 55:577-9. 2010..We demonstrate a rare case of TMZ-related ALL in a child with glioma possibly associated with a germline TP53 mutation... - Prognostic value of immunohistochemical profile and response to high-dose methotrexate therapy in primary CNS lymphomaHiroyuki Momota
Department of Neurosurgery, Nagoya University, Graduate School of Medicine, 65, Tsurumai cho, Showa Ku, Nagoya 466 8550, Japan
J Neurooncol 98:341-8. 2010..However, the response itself was a significant predictor for both progression-free survival (P < 0.001) and overall survival (P = 0.003). Further investigation is needed to assess BCL-6 as a potential prognostic factor in PCNSL... - Mouse models of CNS embryonal tumorsHiroyuki Momota
Neurosurgery Division, National Cancer Center Hospital, 5 1 1, Tsukiji, Chuo Ku, Tokyo, 104 0045, Japan
Brain Tumor Pathol 26:43-50. 2009..These data provide insight into the biology and classification of CNS embryonal tumors... - Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomasKazuya Motomura
Department of Neurosurgery, Nagoya University School of Medicine, Japan
Cancer Sci 103:1871-9. 2012..This is the first study to establish a subclassification of GBM on the basis of immunohistochemical analysis. Our study will shed light on personalized therapies that might be feasible in daily neuropathological practice... - Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapyKazuya Motomura
Department of Neurosurgery, Nagoya University School of Medicine, Nagoya, Japan
Leuk Lymphoma 52:2069-75. 2011..Our study investigated the efficacy of DeVIC chemotherapy in PCNSL patients, and found it to result in favorable survival outcomes in these patients, thus warranting further investigation of it as a therapeutic measure against PCNSL... - A novel method of intracranial injection via the postglenoid foramen for brain tumor mouse modelsKenichiro Iwami
Department of Neurosurgery, Nagoya University, Graduate School of Medicine, Nagoya, Japan
J Neurosurg 116:630-5. 2012..The aim of this study was to establish a simple and accurate method for intracranial injection of cells or other materials into mice... - [A survey of neurosurgeons' policies and attitudes regarding the disclosure of a diagnosis of glioma and the decision to pursue end-of-life care in glioma patients]Yoshitaka Narita
Neurosurgery Division, National Cancer Center Hospital, 5 1 1 Tsukiji, Chuo Ku, Tokyo 104 0045, Japan
No Shinkei Geka 37:973-81. 2009..We surveyed neurosurgeons in Japan with regard to their policies and attitudes concerning the disclosure of a diagnosis of glioma and their thoughts on the end-of-life care of glioma patients... 
The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for gliomaFumiharu Ohka
Department of Neurosurgery, Nagoya University School of Medicine, Nagoya, Japan
PLoS ONE 6:e23332. 2011..As a global DNA methylation marker, LINE-1 may be a promising marker in gliomas...- Glioblastoma simultaneously present with adjacent meningioma: case report and review of the literatureKengo Suzuki
Department of Neurosurgery, Sapporo Medical University School of Medicine, South 1, West 16, Chuo Ku, Sapporo 060 8543, Japan
J Neurooncol 99:147-53. 2010..The PDGF-mediated paracrine system may induce one tumor from another... - Immunohistochemical analysis of the p53 family members in human craniopharyngiomasHiroyuki Momota
Department of Pathology, Sapporo Medical University School of Medicine, South 1, West 17, Chuo Ku, Sapporo 060 8556, Japan
Brain Tumor Pathol 20:73-7. 2003.... - p73 is expressed in human thymic epithelial cellsShingo Ichimiya
Department of Pathology, Sapporo Medical University School of Medicine, South 1 West 17, Chuo Ku, Sapporo 060 8556, Japan
J Histochem Cytochem 50:455-62. 2002..Because p73 has the capacity to be a transactivator like p53, it may contribute to T-cell development in the context of TEC biology as regulated in the cell cycle and apoptosis...