Research Topics
| Takeo MinematsuSummaryAffiliation: University of Tokyo Country: Japan Publications
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Detail Information
Publications
Aging enhances maceration-induced ultrastructural alteration of the epidermis and impairment of skin barrier functionTakeo Minematsu
Department of Advanced Skin Care, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
J Dermatol Sci 62:160-8. 2011..In health care settings, incontinence-associated skin maceration is highly prevalent in the elderly. However, the effect of senescence on maceration has not been fully elucidated...
The dual origin of the peripheral olfactory system: placode and neural crestHiroyuki Katoh
Department of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku ku, Tokyo, Japan
Mol Brain 4:34. 2011....
Novel models for bacterial colonization and infection of full-thickness wounds in ratsMayumi Asada
Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Wound Repair Regen 20:601-10. 2012..Wounds were made 2 cm cranial to the greater trochanter. These clinically relevant and highly reproducible animal models can be used to investigate the mechanisms of wound infection and monitor the effect of therapeutic agents in vivo...
Novel biomarkers for the detection of wound infection by wound fluid RT-PCR in ratsMayumi Asada
Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
Exp Dermatol 21:118-22. 2012..We anticipate that wound fluid RT-PCR could be applied in the future to diagnose wound infection...
Altered expression of matrix metalloproteinases and their tissue inhibitors in matured rat adipocytes in vitroTakeo Minematsu
Department of Advanced Skin Care, The University of Tokyo, Tokyo, Japan
Biol Res Nurs 14:242-9. 2012..Further studies to determine the effect of other obesity-related factors, such as insulin resistance, on MMPs and TIMPs are required...
Aging-like skin changes induced by ultraviolet irradiation in an animal model of metabolic syndromeTomoko Akase
Department of Gerontological Nursing Wound Care Management, Division of Health Science and Nursing, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
Biol Res Nurs 14:180-7. 2012..These results suggest that UV-irradiated TSOD mice may provide a new model of skin aging and imply that skin from humans with MS is more susceptible to UV- or aging-related damage than normal human skin...
Candidate biomarkers for deep tissue damage from molecular biological and biochemical aspectsTakeo Minematsu
Department of Advanced Skin Care, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
J Tissue Viability 19:77-83. 2010..Our results using PU model rats suggested that exudate CPK could be a more sensitive biomarker than serum CPK for deep muscle tissue injury, and could be applicable for clinical diagnosis of DTI...
The Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl) homoserine lactone can accelerate cutaneous wound healing through myofibroblast differentiation in ratsGojiro Nakagami
Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, Faculty of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
FEMS Immunol Med Microbiol 62:157-63. 2011....
Skin fragility in obese diabetic mice: possible involvement of elevated oxidative stress and upregulation of matrix metalloproteinasesAi Ibuki
Department of Gerontological Nursing Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Exp Dermatol 21:178-83. 2012..These observations may contribute to novel clinical interventions, such as dietary supplementation with antioxidants or application of skin cream containing antioxidants, which may overcome skin fragility in obese patients with diabetes...
Factors associated with deep foot fissures in diabetic patients: a cross-sectional observational studyMakoto Oe
Department of Gerontological Nursing, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Int J Nurs Stud 49:739-46. 2012..However, distinctions between superficial and deep fissures have not been well described, and specific factors involved in their development are generally unknown...
Do nutritional markers in wound fluid reflect pressure ulcer status?Shinji Iizaka
Department of Gerontological Nursing Wound Care Management, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Wound Repair Regen 18:31-7. 2010..61, p=0.028). Our results suggest that these traditional nutritional markers in wound fluid, especially wound fluid/serum ratio may be useful to evaluate local PU status...
