Shinichi Kuriyama

..In Asia, there has been no population-based epidemiological study using the K6, a 6-item instrument that assesses nonspecific psychological distress...

..The associations were robust after adjustment for different potential confounders. This population-based prospective cohort study indicates that a history of cholelithiasis is associated with an increased incidence of prostate cancer...

..Therefore we investigated the relationship between dietary patterns and fall-related fractures in the elderly...

..47 (95% CI, -1.97 to 1.02). These results suggest that the presence of the Trp64Arg variant of the beta(3)-adrenergic receptor gene may not play a major role as a hindrance to weight reduction...

..The objectives of the present study were to estimate an annual number of patients with moyamoya disease in Japan and to describe the clinicoepidemiological features of the disease...

....

..The objective of this study was to examine the joint impact of modifiable health-risk factors such as smoking, obesity, and physical inactivity on direct health care charges...

..These results from RCT suggest a plausible mechanism for the beneficial effects of green tea and provide substantial support for our observations...

..The aim of this study is to examine the association between obesity and depressive symptoms in Japan...

..Green tea polyphenols have been extensively studied as cardiovascular disease and cancer chemopreventive agents in vitro and in animal studies. However, the effects of green tea consumption in humans remain unclear...

..2% (all subjects) or 3.7% (never-smokers) in men. The value for women was within the range among women reported from Western populations (3.2%-8.8%). Our data demonstrate that excess weight is a major cancer risk among Japanese women...

..5% in women, which were within the range reported from Western populations, from 3.2% for US women to 8.8% for Spanish women. Our data suggests that excess body weight is a problem not only in Western countries but also in Japan...

....

..CONCLUSONS: In this prospective cohort study of middle-aged men and women in rural Japan, a larger number of high-risk practices was associated with linear increase in risk of all-cause mortality...

..These associations were partly explained by vitamin C intake. Other dietary intakes had no association. Intake of fruits may have a beneficial effect against oxidative stress in elderly Japanese...

..Large-scale cohort studies conducted in Japan do not always include psychosocial factors as exposures. In addition, such studies sometimes fail to satisfactorily evaluate disability status as an outcome...

..We conclude that there is a significant increase in the risk of depression status associated with the lack of social support in Japanese elderly people in an urban community...

..To determine the associations between personality subscales and attendance at gastric cancer screenings in Japan...

..Further study is required to clarify the causality of this relationship...

..However, no evidence from cohort studies is available for Asian populations, whose lifestyle is very different from that of westerners...

..7). This prospective cohort study indicated a positive linear association between alcohol consumption and the risk of suicide, and the suicide risk among the light drinkers was not decreased as compared with that in nondrinkers...

..2). These data indicate that alcohol consumption in Japanese men is associated with a statistically significant increased risk of cancer of the distal colon and rectum, but not cancer of the proximal colon...

..Although ecological observations suggest that the Japanese diet may reduce the risk of cardiovascular disease (CVD), the impact of a Japanese dietary pattern upon mortality due to CVD is unclear...

..To clarify the effect of age on the association between body mass index (BMI) and all-cause mortality...

..Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions...

..32, 1.78) for myeloid neoplasms. This inverse association was consistent across sex and body mass index strata. In conclusion, green tea consumption was associated with a lower risk of hematologic malignancies...

..To investigate the association between green tea consumption and liver cancer incidence...

..Our results suggest that coffee may have favorable effects on morality due to all causes and to CVD, especially CHD, in women...

..Therefore, it is still unclear whether a greater consumption of n-3 PUFAs is associated with lower serum CRP concentrations...

..5 or higher in men and 18.5 to 29.9 in women). CONCLUSIONS: The risk of death from all causes increases in lean men and women, and obese women in this cohort...

..We expect this data to contribute to the progress of research on cancer etiology and cancer prevention...

..Further study is required to clarify whether reducing CRP by intervention is a cost-effective measure...

..Screening by mammography combined with CBE may therefore not be sufficiently sensitive for women ranging from 40 to 49 years of age...

..In conclusion, coffee consumption was associated with a lower risk of oral, pharyngeal, and esophageal cancers, even in the group at high risk of these cancers...

..This study aimed to investigate the association between gastric cancer screening and mortality from gastric cancer...

....

..Although it is expected that green tea consumption would lower the risk of incident functional disability, this has never been investigated directly...

..Past studies have measured and described the length of life with disability before death, but there has been no study of the relationship between modifiable lifestyle factors and duration of disability...

..Therefore, it is still unclear whether a lower CRP is favorably associated with physical performance even within a very low range...

..No data are available on the association between green tea consumption and the risk of pneumonia in humans...

..Although green tea or its constituents might reduce psychological stress, the relation between green tea consumption and psychological distress has not been investigated in a large-scale study...

..The aim of this study was to measure the prevalence of and risk factors for overactive bladder (OAB) in the elderly...

..To clarify the clinicoepidemiological features of autoimmune pancreatitis (AIP) in Japan, the nationwide survey was conducted...

..A nationwide survey was conducted to clarify the epidemiological features of patients with chronic pancreatitis (CP) in Japan...

..The present study investigated the association between GGT and cancer incidence and assessed the role of alcohol consumption in this association...

..However, no studies have reported the fraction...

..CONCLUSIONS: In this cohort study, both the participation rate and the follow-up rate are satisfactorily high. We expect this Miyagi Cohort Study to provide the society with evidence for health promotion and disease prevention...

..The purpose of the present study was to examine the association between alcohol consumption and in-patient and out-patient care utilization and its costs, respectively...

..This cross-sectional study included 1150 community-dwelling Japanese aged 70 years or older in 2002...

..The objective of this study was to examine the relation between body mass index (BMI) and cardiovascular disease in Japan, where the proportion of the population that is underweight is relatively high...

..The psychological factors play important roles in morbidity and mortality risks. However, the association between the negative psychological factors and the risk of mortality is inconclusive...

..96 (0.68-12.83) and 9.51 (2.36-38.26), respectively. After adjusting for stage, the HRs dropped remarkably. Screening mammography may be more effective in the elderly group and be able to reduce the mortality of breast cancer in Japan...

..To examine the association between green tea consumption and tooth loss...

..The aim of this study was to investigate whether peripheral arterial disease (PAD) is predictive of disability and whether the relationship between PAD and disability can be fully explained by baseline physical functions...

..Coffee consumption was also not associated with incidence of either proximal or distal colon cancer. We conclude that coffee consumption is not associated with the incidence risk of colorectal cancer in the general population in Japan...

..003). Time spent walking per day was associated with a lower risk of colon cancer in Japanese men but not in women, and there was no association between time spent walking and the risk of rectal cancer...

..The purpose of the present study was to elucidate the relationship with stratified analyses by alcohol intake category and smoking status...

..To investigate the association between green tea consumption and the risk of endometrial cancer restricted to endometrial endometrioid adenocarcinoma (EEA) using a case-control design in Japan...

..Although these functions might be associated with the development and progression of depressive symptoms, no studies have investigated the relation between green tea consumption and depressive symptoms in a community-dwelling population...

..Further work on the specific citrus constituents is warranted, and clinical trials are ultimately necessary to confirm the protective effect...

..The joint impact of obesity, hypertension, and hyperglycemia upon medical costs is not well known. Our objective was to evaluate the joint impact of these cardiovascular risk factors upon medical costs in the rural Japanese population...

..The purpose of this study was to propose a suitable cut-off point for the serum albumin value to predict which elderly individuals are qualified for long-term care insurance certification and those at risk of death...

..Our results suggest that pain is associated with an increased risk of completed suicide among Japanese men. The association was consistently observed among apparently healthy subjects...

..02). Our findings suggest that parity number and age at menopause have great effects on breast cancer risk among Japanese women...

..We therefore investigated the association between fish intake and the risk of prostate cancer in a prospective cohort study in Japan...

..The purpose of this study was to examine the relationship between depressive status and subsequent certification of long-term care insurance use, and to investigate sex differences in this relationship in an elderly Japanese population...

..Our findings support the hypothesis that coffee consumption decreases the risk of liver cancer. Further studies to investigate the role of coffee in prevention of liver cancer among the high-risk population are needed...

..This is the first study to clarify that the positive significant relation between CRP and hypertension was independent of LTPA levels among Japanese elderly...

..90). This study thus revealed an inverse dose-response relationship between coffee consumption and the risk of EEA, and its strong association in postmenopausal women but not in premenopausal women...

....

..However, several recent prospective studies have reported no association. We therefore examined the association between fruit and vegetable intakes and the risk of colorectal cancer in a prospective cohort study in Japan...

..We also found no significant association between total meat consumption and the risk of sub-site of colorectal cancer. In conclusion, our data do not support the hypothesis that meat consumption is a risk factor for colorectal cancer...

..05). Our findings are consistent with the hypothesis that cigarette smoking is associated with a higher risk of colorectal cancer in men...

..0%, 48.6%, and 22.1%, respectively. CONCLUSIONS: Among the variables studied, smoking has the largest public health impact on esophageal cancer incidence in Japanese men, followed by alcohol drinking and green tea drinking...

..Thus, the level of plasma 8-isoprostane appears to be elevated in older subjects with severe hypertension...

..06 and 0.01 mmHg when the outside temperature was <10°C. In conclusion, inverse association between outside temperature and BP was observed only in warmer seasons...

..The risk was increased for both differentiated and nondifferentiated histologic subtypes. Our findings support the hypothesis that cigarette smoking is a risk factor for gastric cancer...

..The role of personality in the causation of circulatory diseases has been controversial...

....

..We attempted to quantify the association between time spent walking and medical care costs, based on a 4-year prospective observation of National Health Insurance (NHI) beneficiaries in rural Japan...

....

..CONCLUSION: CVL was associated with DS independent of various confounders. However, clarification of clinical profiles is required to define MRI-VD as an independent clinical entity...

..Parameters, including eligible age group, target group, and method, widely differed among the municipalities. A standardized system for cancer screening programs should be recommended...

..2 (0.8-1.8),(3) 1.4 (1.0-2.0),(4) 1.6 (1.1-2.3),(5) 2.0 (1.4-2.9) in women. A significant association was found between social support and depression in this elderly population. We also found that this association was stronger in men...

....

....

..The intensive intervention, two sessions of individual education classes per month, was significantly more effective than the moderate one for reducing body weight...

..While the annual combined modality was the most effective with respect to life-years saved among women aged 40-49 years, biennial combined modality was found to provide the highest cost-effectiveness...

..We hypothesized that the weekend enema therapy would be better tolerated by patients who worked or attended school...

..80+/-0.03; AUC for Model 1, 0.69+/-0.04; P<0.001). Addition of ALB, LDH, and Lymp% to PS and physical symptoms improved prediction accuracy, especially for longer survival...

..Thus, a high level of CRP is related to a low ankle brachial index among Japanese elderly as well as Western subjects. This is the first study to report the relationship between CRP and low ankle brachial index among Japanese elderly...

..However, breast cancer mortality has declined after introducing the screening mammography in many Western nations, and the guidelines for breast cancer screening were not changed in the countries...