Shinsuke Koike

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. doi request reprint Association between rostral prefrontal cortical activity and functional outcome in first-episode psychosis: a longitudinal functional near-infrared spectroscopy study
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan Office for Mental Health Support, Division for Counseling and Support, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan Electronic address
    Schizophr Res 170:304-10. 2016
  2. doi request reprint Long-term effect of a name change for schizophrenia on reducing stigma
    Shinsuke Koike
    Division for Counseling and Support, Office for Mental Health Support, The University of Tokyo, Yasuda Auditorium, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8654, Japan
    Soc Psychiatry Psychiatr Epidemiol 50:1519-26. 2015
  3. doi request reprint Multi-modal brain imaging showing brain damage to the orbitofrontal cortex and left hemisphere, in a case of prolonged hypoglycemia-induced transient hemiplegia followed by persistent encephalopathy
    Shinsuke Koike
    Department of Psychiatry, Tokyo Metropolitan Bokuto Hospital, Tokyo, Japan
    Psychiatry Clin Neurosci 67:360-2. 2013
  4. doi request reprint Reduced but broader prefrontal activity in patients with schizophrenia during n-back working memory tasks: a multi-channel near-infrared spectroscopy study
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    J Psychiatr Res 47:1240-6. 2013
  5. doi request reprint A multimodal approach to investigate biomarkers for psychosis in a clinical setting: the integrative neuroimaging studies in schizophrenia targeting for early intervention and prevention (IN-STEP) project
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 143:116-24. 2013
  6. doi request reprint Association between severe dorsolateral prefrontal dysfunction during random number generation and earlier onset in schizophrenia
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Neurophysiol 122:1533-40. 2011
  7. pmc Comprehensive early intervention for patients with first-episode psychosis in Japan (J-CAP): study protocol for a randomised controlled trial
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, 113 8655, Japan
    Trials 12:156. 2011
  8. doi request reprint Different hemodynamic response patterns in the prefrontal cortical sub-regions according to the clinical stages of psychosis
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 132:54-61. 2011
  9. doi request reprint Association of decreased prefrontal hemodynamic response during a verbal fluency task with EGR3 gene polymorphism in patients with schizophrenia and in healthy individuals
    Yukika Nishimura
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Department of Youth Mental Health, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Electronic address
    Neuroimage 85:527-34. 2014
  10. doi request reprint Potential biomarker of subjective quality of life: prefrontal activation measurement by near-infrared spectroscopy
    Yoshihiro Satomura
    a Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo Study Site, Bunkyo ku, Tokyo, Japan
    Soc Neurosci 9:63-73. 2014

Collaborators

Detail Information

Publications26

  1. doi request reprint Association between rostral prefrontal cortical activity and functional outcome in first-episode psychosis: a longitudinal functional near-infrared spectroscopy study
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan Office for Mental Health Support, Division for Counseling and Support, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan Electronic address
    Schizophr Res 170:304-10. 2016
    ..To develop such biomarker using multichannel functional near-infrared spectroscopy (fNIRS), cortical function in the prefrontal cortex was longitudinally measured during a verbal fluency task...
  2. doi request reprint Long-term effect of a name change for schizophrenia on reducing stigma
    Shinsuke Koike
    Division for Counseling and Support, Office for Mental Health Support, The University of Tokyo, Yasuda Auditorium, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8654, Japan
    Soc Psychiatry Psychiatr Epidemiol 50:1519-26. 2015
    ..A name change for schizophrenia was first implemented in Japan for reducing stigma in 2002; however, little is known of its long-term impact...
  3. doi request reprint Multi-modal brain imaging showing brain damage to the orbitofrontal cortex and left hemisphere, in a case of prolonged hypoglycemia-induced transient hemiplegia followed by persistent encephalopathy
    Shinsuke Koike
    Department of Psychiatry, Tokyo Metropolitan Bokuto Hospital, Tokyo, Japan
    Psychiatry Clin Neurosci 67:360-2. 2013
    ..Transient hemiplegia corresponded to abnormal waveforms on EEG and decreased cerebral blood flow on SPECT, whereas persistent dysfunctions corresponded to abnormal brain regions on MRI and SPECT. ..
  4. doi request reprint Reduced but broader prefrontal activity in patients with schizophrenia during n-back working memory tasks: a multi-channel near-infrared spectroscopy study
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    J Psychiatr Res 47:1240-6. 2013
    ....
  5. doi request reprint A multimodal approach to investigate biomarkers for psychosis in a clinical setting: the integrative neuroimaging studies in schizophrenia targeting for early intervention and prevention (IN-STEP) project
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 143:116-24. 2013
    ..0%, and 35.3% (at 6, 12, and 24months, respectively). Through this research project, we expect to clarify the pathophysiological features around the onset of psychosis and improve the prognosis of psychosis through clinical application...
  6. doi request reprint Association between severe dorsolateral prefrontal dysfunction during random number generation and earlier onset in schizophrenia
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Neurophysiol 122:1533-40. 2011
    ..Age at onset is a major factor for predicting social outcome in schizophrenia. In clinical settings, we need an objective assessment tool for evaluating prefrontal function and social outcome...
  7. pmc Comprehensive early intervention for patients with first-episode psychosis in Japan (J-CAP): study protocol for a randomised controlled trial
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, 113 8655, Japan
    Trials 12:156. 2011
    ..The purpose of this trial is to investigate the effectiveness and affordability of 18-month comprehensive early intervention services for patients with first-episode psychosis compared with typical treatment...
  8. doi request reprint Different hemodynamic response patterns in the prefrontal cortical sub-regions according to the clinical stages of psychosis
    Shinsuke Koike
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 132:54-61. 2011
    ..Multichannel near-infrared spectroscopy (NIRS), which can easily and noninvasively measure hemodynamics over the prefrontal cortex, is a candidate instrument for clinical use...
  9. doi request reprint Association of decreased prefrontal hemodynamic response during a verbal fluency task with EGR3 gene polymorphism in patients with schizophrenia and in healthy individuals
    Yukika Nishimura
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Department of Youth Mental Health, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan Electronic address
    Neuroimage 85:527-34. 2014
    ..Genetic variation in EGR3 may affect prefrontal function through neurodevelopment. This study illustrates the usefulness of NIRS in imaging genetics investigations on psychiatric disorders. ..
  10. doi request reprint Potential biomarker of subjective quality of life: prefrontal activation measurement by near-infrared spectroscopy
    Yoshihiro Satomura
    a Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo Study Site, Bunkyo ku, Tokyo, Japan
    Soc Neurosci 9:63-73. 2014
    ..These findings suggest that subjective QOL has possible involvement in prefrontal function and that NIRS potentially plays a role as a biological marker of subjective QOL...
  11. doi request reprint Genetic influences on prefrontal activation during a verbal fluency task in adults: a twin study based on multichannel near-infrared spectroscopy
    Eisuke Sakakibara
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan 2 Department of Psychiatry, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan Electronic address
    Neuroimage 85:508-17. 2014
    ..This implies that the prefrontal hemodynamic dysfunction observed during an executive function task measured by NIRS may be an efficient endophenotype for large-scale imaging genetic studies in psychiatric disorders. ..
  12. doi request reprint Effect of metabotropic glutamate receptor-3 variants on prefrontal brain activity in schizophrenia: An imaging genetics study using multi-channel near-infrared spectroscopy
    Akihide Kinoshita
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 62:14-21. 2015
    ..We thus explored an association between genetic variations in GRM3 and brain activation driven by a cognitive task in the prefrontal cortex in patients with schizophrenia...
  13. doi request reprint Localized gray matter volume reductions in the pars triangularis of the inferior frontal gyrus in individuals at clinical high-risk for psychosis and first episode for schizophrenia
    Norichika Iwashiro
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 137:124-31. 2012
    ..The right PT might preferentially contribute to the pathogenesis of psychotic symptoms...
  14. pmc Reduced frontal glutamate + glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical high risk for psychosis or with first-episode schizophrenia
    Tatsunobu Natsubori
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Schizophr Bull 40:1128-39. 2014
    ....
  15. pmc Altered metabolites in the plasma of autism spectrum disorder: a capillary electrophoresis time-of-flight mass spectroscopy study
    Hitoshi Kuwabara
    Department of Child Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, Japan
    PLoS ONE 8:e73814. 2013
    ..001) and low lactic acid (pā€Š=ā€Š0.003) in the combined sample (nā€Š=ā€Š53). The present study identified deviated plasma metabolite levels associated with oxidative stress and mitochondrial dysfunction in individuals with ASD. ..
  16. doi request reprint Characterizing prefrontal cortical activity during inhibition task in methamphetamine-associated psychosis versus schizophrenia: a multi-channel near-infrared spectroscopy study
    Naohiro Okada
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Japan
    Addict Biol 21:489-503. 2016
    ....
  17. doi request reprint Using social epidemiology and neuroscience to explore the relationship between job stress and frontotemporal cortex activity among workers
    Shingo Kawasaki
    a Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Soc Neurosci 10:230-42. 2015
    ..Integrating social epidemiology and neuroscience may be a powerful strategy for understanding how individuals' brain functions may mediate between the job-related stress or psychosocial work characteristics and public mental health...
  18. pmc Similar age-related decline in cortical activity over frontotemporal regions in schizophrenia: a multichannel near-infrared spectroscopy study
    Po Han Chou
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan Department of Psychiatry, Taichung Veterans General Hospital, Taichung City, Taiwan
    Schizophr Bull 41:268-79. 2015
    ..This study investigated age effects on regional brain cortical activity to determine whether there is similar age-related decline in cortical activity as those observed in cortical thickness and cognitive test performance...
  19. doi request reprint Distinct effects of duration of untreated psychosis on brain cortical activities in different treatment phases of schizophrenia: a multi-channel near-infrared spectroscopy study
    Po Han Chou
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo, 113 8655, Japan Department of Psychiatry, Taichung Veterans General Hospital, Taichung City, 40705, Taiwan
    Prog Neuropsychopharmacol Biol Psychiatry 49:63-9. 2014
    ..In the present study, we used near-infrared spectroscopy (NIRS) to investigate the influence of DUP on brain functions during a verbal fluency test (VFT) in patients with schizophrenia...
  20. doi request reprint Differential Alterations of Auditory Gamma Oscillatory Responses Between Pre-Onset High-Risk Individuals and First-Episode Schizophrenia
    Mariko Tada
    Department of Neuropsychiatry, Graduate School of Medicine
    Cereb Cortex 26:1027-35. 2016
    ..The late-latency ASSR alteration may represent a biomarker for early detection of psychosis, while the early-latency ASSR abnormality may develop through the onset of psychosis. ..
  21. doi request reprint An fMRI study of visual lexical decision in patients with schizophrenia and clinical high-risk individuals
    Tatsunobu Natsubori
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Schizophr Res 157:218-24. 2014
    ..Furthermore, the current result may suggest that the genetic basis of psychosis is presumed to be related to the evolution of the language capacity characteristic of humans. ..
  22. doi request reprint Comprehensive DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia
    Masaki Nishioka
    Department of Molecular Psychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Hum Genet 58:91-7. 2013
    ..Our results indicate the site-specific epigenetic alterations in patients with FESZ...
  23. ncbi request reprint [Biological study in schizophrenia]
    Kiyoto Kasai
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Brain Nerve 64:109-18. 2012
    ..Additionally, we present the preliminary findings of the clinical research in our outpatient unit, specialized for early intervention, at the University of Tokyo Hospital...
  24. doi request reprint Development of a Japanese version of the reported and intended behaviour scale: reliability and validity
    Sosei Yamaguchi
    Department of Psychiatric Rehabilitation, Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan
    Psychiatry Clin Neurosci 68:448-55. 2014
    ..to measure mental health-related behavior. The current study aimed to evaluate the applicability, and reliability of a Japanese version of the RIBS (RIBS-J) in a Japanese context, and further examine the construct validity of the RIBS-J...
  25. ncbi request reprint [Clinical status and outcome biomarkers in schizophrenia: a review for near-infrared spectroscopy studies]
    Shinsuke Koike
    Office for Mental Health Support, Division for Counseling and Support, The University of Tokyo
    Seishin Shinkeigaku Zasshi 115:863-73. 2013
    ..It is hoped that findings will support the development of new biomarkers that will facilitate differential diagnosis, better understanding of present conditions and prognosis, and decisions regarding treatment options...