Research Topics
Genomes and Genes | F KishiSummaryAffiliation: University of Tokyo Country: Japan Publications
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Publications
Heme and non-heme iron transporters in non-polarized and polarized cellsIzumi Yanatori
Department of Molecular Genetics, Kawasaki Medical School, Okayama 701 0192, Japan
BMC Cell Biol 11:39. 2010..To specify the processes of heme uptake and degradation, and the reutilization of iron, we determined the subcellular localizations of these transporters and HOs...
Human natural resistance-associated macrophage protein 2: gene cloning and protein identificationF Kishi
Center for Gene Research, Yamaguchi University, 1144 Kogushi, Yamaguchi, Ube, 755 8505, Japan
Biochem Biophys Res Commun 251:775-83. 1998..The protein product of the human NRAMP2 gene is apparently present in human cultured cell lines as a 64 kDa protein recognized by this antibody, which is consistent with the molecular mass deduced from the human NRAMP2 cDNA...- Dinucleotide repeat polymorphism in the third intron of the NRAMP2/DMT1 geneF Kishi
Center for Gene Research, Yamaguchi University, Japan
J Hum Genet 44:425-7. 1999..We found a polymorphic dinucleotide repeat in the third intron of the NRAMP2 gene. This polymorphism will be a useful genetic marker to study disease associated with susceptibility to infection with intracellular pathogens... - Novel forms of squamous cell carcinoma antigen transcripts produced by alternative splicingY Suminami
Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine, Minamikogushi, Ube, Japan
Biochim Biophys Acta 1519:122-6. 2001..A comparison of SCCA1b and SCCA2b cDNA with the SCCA1 and SCCA2 genes showed that these messages were derived from each gene by an alternative splicing mechanism... - Comparison of outer membrane protein genes omp and pmp in the whole genome sequences of Chlamydia pneumoniae isolates from Japan and the United StatesM Shirai
Dept of Microbiology, Yamaguchi University School of Medicine, Ube, Yamaguchi 755 8505, Japan
J Infect Dis 181:S524-7. 2000..The overall genomic organization and location of genes are identical in both strains. Thus, a few unique sequences of the OMPs may be essential for specific attributes that define the differential biology of two C. pneumoniae strains... - Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USAM Shirai
Department of Microbiology, Yamaguchi University School of Medicine, Minamikogushi 1 1 1, Ube, Yamaguchi 755 8505, Japan
Nucleic Acids Res 28:2311-4. 2000..The complex organization of these 'different zones' may be attributable to a unique system of recombination... - Human NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cellsM Tabuchi
Center for Gene Research, Yamaguchi University and the Institute of Laboratory Animals, Yamaguchi University School of Medicine, 1 1 1 Minami kogushi, Ube, Yamaguchi 755 8505, Japan
J Biol Chem 275:22220-8. 2000..These results indicated that NRAMP2 is localized to the late endosomes and lysosomes, where NRAMP2 may function to transfer the endosomal free Fe(2+) into the cytoplasm in the transferrin cycle... - Identification of natural resistance-associated macrophage protein in peripheral blood lymphocytesF Kishi
Center for Gene Research, Yamaguchi University, Japan
Immunol Lett 47:93-6. 1995..Bacterial lipopolysaccharide or interferon-gamma did not appear to stimulate the level of Nramp expression in PBL... - Complete nucleotide sequence of human NRAMP2 cDNAF Kishi
Center for Gene Research, Yamaguchi University, Ube, Japan
Mol Immunol 34:839-42. 1997..This suggests that the NH2-terminal region of the NRAMP2 molecule may have a particular function, different from that of the NRAMP1 molecule... - Structural analysis of human SCC antigen 2 promoterY Sakaguchi
Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine, 1144 Kogushi, Ube 755 8505, Japan
Biochim Biophys Acta 1444:111-6. 1999..Analysis of luciferase reporter gene expression in transient transfection showed that the promoter region of SCCA2 gene was located within the region from -424 to +47... - Cloning and characterization of adenylate kinase from Chlamydia pneumoniaeK Miura
Department of Biochemistry, Central Laboratory for Biomedical Research and Education, Yamaguchi University School of Medicine, 1 1 1 Minami kogushi, Ube, Yamaguchi 755 8505, Japan
J Biol Chem 276:13490-8. 2001..Furthermore, the catalytic properties of AKcpn suggest a distinctive regulatory mechanism in the metabolism compared with AKs in other organisms... 
Development and evaluation of a loop-mediated isothermal amplification method for the rapid detection of Chlamydophila pneumoniaeY Kawai
Department of Pediatrics, Kawasaki Medical School, Okayama, Japan
Eur J Clin Microbiol Infect Dis 28:801-5. 2009..Among nasopharyngeal swab specimens from 120 patients with acute respiratory tract infections and 40 healthy individuals, the LAMP results showed 100% agreement with the results of real-time polymerase chain reaction (PCR) assays...- Nucleotide sequence of the human liver-type alkaline phosphatase cDNAF Kishi
Department of Pediatrics, Yamaguchi University School of Medicine, Ube, Japan
Nucleic Acids Res 17:2129. 1989 - Squamous cell carcinoma antigen is a new member of the serine protease inhibitorsY Suminami
Division of Obstetrics and Gynecology, Onoda Municipal Hospital, Yamaguchi, Japan
Biochem Biophys Res Commun 181:51-8. 1991..The amino acid homology search revealed that SCC antigen was a member of the serine protease inhibitors family... - Human adenylate kinase deficiency associated with hemolytic anemia. A single base substitution affecting solubility and catalytic activity of the cytosolic adenylate kinaseS Matsuura
Department of Biochemistry, Yamaguchi University School of Medicine, Ube, Japan
J Biol Chem 264:10148-55. 1989..Analysis on phosphocellulose chromatography of erythrocyte AK1 of the patient and parents revealed that the patient's mutant allele was derived from the mother... - Iron-dependent regulation of the divalent metal ion transporterH Gunshin
Membrane Biology Program and Renal Division, Brigham and Women s Hospital and Harvard Medical School, Harvard Institutes of Medicine, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
FEBS Lett 509:309-16. 2001..We propose that regulation of DCT1/DMT1 mRNA by iron involves post-transcriptional regulation through the binding of IRP1 to the transporter's IRE, as well as other as yet unknown factors... - Isolation and characterization of human Nramp cDNAF Kishi
Department of Pediatrics, Yamaguchi University School of Medicine, Japan
Biochem Biophys Res Commun 204:1074-80. 1994..Southern blot analysis indicated a single gene for Nramp counterpart in the human genome. Northern blot analysis revealed a single species of mRNA of approximately 2.5 kb... - Cloning, DNA sequencing, and amino acid sequencing of catechol 1,2-dioxygenases (pyrocatechase) from Pseudomonas putida mt-2 and Pseudomonas arvilla C-1C Nakai
Department of Biochemistry, Shiga University of Medical Science, Japan
Arch Biochem Biophys 321:353-62. 1995..Tyrosyl and histidyl residues for proposed ligands of ferric ion are conserved in all catechol 1,2-dioxygenases... - Mechanism of adenylate kinase. Are the essential lysines essential?G C Tian
Department of Chemistry, Ohio State University, Columbus 43210
Biochemistry 29:4296-304. 1990..Other than this, the 1H NMR spectrum of K27M is very similar to that of WT, suggesting little perturbation in the global or even local conformations.(ABSTRACT TRUNCATED AT 250 WORDS).. - Isolation and characterization of the gene encoding bovine adenylate kinase isozyme 2H Tanaka
Department of Biochemistry, Yamaguchi University School of Medicine, Japan
Gene 93:221-7. 1990..S1 mapping and primer extension analyses revealed multiple transcription start points. The 581-bp region just upstream from the start codon functions as a promoter in the expression of the cat gene in Chinese hamster ovary cells... - Characterization of a 5'-flanking region of the human liver/bone/kidney alkaline phosphatase gene: two kinds of mRNA from a single geneS Matsuura
Department of Pediatrics, Yamaguchi University School of Medicine, Japan
Biochem Biophys Res Commun 168:993-1000. 1990..4 kb upstream from exon 2 and the alternative splicing in the first exon was indicated. RNA blot analysis showed that three species of mRNA of 2.5, 4.1 and 4.7 kilobases were detected in liver and developmentally regulated... - Cloning and characterization of cDNA for mitochondrial GTP:AMP phosphotransferase of bovine liverM Yamada
Department of Biochemistry, Yamaguchi University School of Medicine, Japan
J Biol Chem 264:19192-9. 1989..coli. The AK3 product was exported to the periplasmic space through the bacterial inner membrane. The possible involvement of the NH2-terminal sequence of the protein in targeting to the mitochondrial matrix was discussed... - Structure and complete nucleotide sequence of the gene encoding chicken cytosolic adenylate kinaseY Suminami
Department of Obstetrics and Gynecology, Yamaguchi University School of Medicine
J Biochem 103:611-7. 1988..The dot matrix plot analysis between chicken AK1 and bovine mitochondrial adenylate kinase (AK2) suggested that the AK1 gene might have evolved from the AK2 gene by deletion of one or more exon(s)... - Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single geneN Kaneda
Biochem Biophys Res Commun 146:971-5. 1987..Southern blot analysis of human genomic DNA indicated that TH is encoded by a single gene. This suggests that the four different forms of TH mRNA are produced by alternative RNA splicing from a single primary transcript... - Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA typesK Kobayashi
Department of Biochemistry, Nagoya University School of Medicine, Aichi
J Biochem 103:907-12. 1988..We propose a possible secondary structure for the latter alternative splicing pathway... - Molecular cloning of cDNA and chromosomal assignment of the gene for human phenylethanolamine N-methyltransferase, the enzyme for epinephrine biosynthesisN Kaneda
Department of Biochemistry, Nagoya University School of Medicine, Japan
J Biol Chem 263:7672-7. 1988..Chromosomal assignment of the gene for human PNMT was carried out using mouse-human somatic cell hybrids. The PNMT gene was assigned to chromosome 17... - Genomic organization of the mouse Lmp-2 gene and characteristic structure of its promoterF Kishi
Department of Pediatrics, Yamaguchi University School of Medicine, Japan
Gene 133:243-8. 1993..The Lmp-2 sequence from a non-obese diabetic (NOD) mouse, a model animal for autoimmune diabetes, was compared with that from a Balb/c mouse... - Leukocyte adhesion deficiency: identification of novel mutations in two Japanese patients with a severe formS Matsuura
Department of Pediatrics, Yamaguchi University School of Medicine, Japan
Biochem Biophys Res Commun 184:1460-7. 1992..The 128th Asp residue is located in a region crucial for the association with alpha subunits and strictly conserved among the integrin beta subunits so far analyzed...