- Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in TongansSean Myles
Institute for Genomic Diversity, Cornell University, Ithaca, NY, USA
BMC Med Genet 12:10. 2011..We suggested that the risk allele of the Gly482Ser variant in the PPARGC1A gene was driven to high frequency in Polynesians by positive selection and therefore possibly represented a thrifty allele in the Pacific...
- A common variation in EDAR is a genetic determinant of shovel-shaped incisorsRyosuke Kimura
Transdisciplinary Research Organization for Subtropics and Island Studies, University of the Ryukyus, Okinawa, 903 0215, Japan
Am J Hum Genet 85:528-35. 2009..The 1540C allele also significantly affected PC1 (p = 4.9 x 10(-3)), which denotes overall tooth size, and PC2 (p = 2.6 x 10(-3)), which denotes the ratio of mesiodistal diameter to buccolingual diameter...