Yoshiya Kawamura

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint DNA polymorphism in the FKBP5 gene affects impulsivity in intertemporal choice
    Yoshiya Kawamura
    Department of Psychiatry, Sakae Seijinkai Hospital, Kanagawa, Japan
    Asia Pac Psychiatry 5:31-8. 2013
  2. doi request reprint A genome-wide CNV association study on panic disorder in a Japanese population
    Yoshiya Kawamura
    Outpatient Clinic for Anxiety Disorders, Yokohama Clinic, Yokohama, Japan
    J Hum Genet 56:852-6. 2011
  3. doi request reprint The association between oxytocin receptor gene (OXTR) polymorphisms and affective temperaments, as measured by TEMPS-A
    Yoshiya Kawamura
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan
    J Affect Disord 127:31-7. 2010
  4. ncbi request reprint Six-year stability of affective temperaments as measured by TEMPS-A
    Yoshiya Kawamura
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo, Tokyo, Japan
    Psychopathology 43:240-7. 2010
  5. doi request reprint Association study of PDE4B with panic disorder in the Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 35:545-9. 2011
  6. doi request reprint An association analysis of Per2 with panic disorder in the Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Hum Genet 56:748-50. 2011
  7. doi request reprint Replication of a genome-wide association study of panic disorder in a Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, The University of Tokyo, Japan
    J Hum Genet 55:91-6. 2010
  8. ncbi request reprint The proposed factor structure of temperament and personality in Japan: combining traits from TEMPS-A and MPT
    Tsuyoshi Akiyama
    Department of Neuropsychiatry, Kanto Medical Center NTT EC, Tokyo, Japan
    J Affect Disord 85:93-100. 2005
  9. doi request reprint Association of the oxytocin receptor (OXTR) gene polymorphisms with autism spectrum disorder (ASD) in the Japanese population
    Xiaoxi Liu
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Hum Genet 55:137-41. 2010
  10. doi request reprint No association between the brain-derived neurotrophic factor gene and panic disorder in Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Hum Genet 54:437-9. 2009

Detail Information

Publications20

  1. ncbi request reprint DNA polymorphism in the FKBP5 gene affects impulsivity in intertemporal choice
    Yoshiya Kawamura
    Department of Psychiatry, Sakae Seijinkai Hospital, Kanagawa, Japan
    Asia Pac Psychiatry 5:31-8. 2013
    ..High cortisol levels are associated with low impulsivity in intertemporal choice. The aim of this study was to explore the effect of single nucleotide polymorphisms (SNPs) in FKBP5 on delay discounting...
  2. doi request reprint A genome-wide CNV association study on panic disorder in a Japanese population
    Yoshiya Kawamura
    Outpatient Clinic for Anxiety Disorders, Yokohama Clinic, Yokohama, Japan
    J Hum Genet 56:852-6. 2011
    ..2, which had been reported to be rich in low copy repeats and to harbor developmental disorders, neuropsychiatric disorders and dysmorphic features...
  3. doi request reprint The association between oxytocin receptor gene (OXTR) polymorphisms and affective temperaments, as measured by TEMPS-A
    Yoshiya Kawamura
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan
    J Affect Disord 127:31-7. 2010
    ..The objective of this study is to assess the association between oxytocin receptor gene (OXTR) polymorphisms and affective temperaments...
  4. ncbi request reprint Six-year stability of affective temperaments as measured by TEMPS-A
    Yoshiya Kawamura
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo, Tokyo, Japan
    Psychopathology 43:240-7. 2010
    ....
  5. doi request reprint Association study of PDE4B with panic disorder in the Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo 113 8655, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 35:545-9. 2011
    ..Several studies indicated that PDE4B may be involved in the regulation of anxiety and depression. Therefore, we investigate the association of PDE4B with PD in the Japanese population...
  6. doi request reprint An association analysis of Per2 with panic disorder in the Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Hum Genet 56:748-50. 2011
    ..046, uncorrected), whereas we could not replicate the association in the second sample of 460 patients and 460 controls. Our results suggest that Per2 may not have a major role in the pathogenesis of PD in the Japanese population...
  7. doi request reprint Replication of a genome-wide association study of panic disorder in a Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, The University of Tokyo, Japan
    J Hum Genet 55:91-6. 2010
    ..Our results failed to show any significant association with PD in these genes. Further studies on these variants with a larger sample size may be worth testing to confirm the results...
  8. ncbi request reprint The proposed factor structure of temperament and personality in Japan: combining traits from TEMPS-A and MPT
    Tsuyoshi Akiyama
    Department of Neuropsychiatry, Kanto Medical Center NTT EC, Tokyo, Japan
    J Affect Disord 85:93-100. 2005
    ..This research investigates the construct validity of these temperaments through factor analysis...
  9. doi request reprint Association of the oxytocin receptor (OXTR) gene polymorphisms with autism spectrum disorder (ASD) in the Japanese population
    Xiaoxi Liu
    Department of Human Genetics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Hum Genet 55:137-41. 2010
    ..In conclusion, our study might support that OXTR has a significant role in conferring the risk of ASD in the Japanese population...
  10. doi request reprint No association between the brain-derived neurotrophic factor gene and panic disorder in Japanese population
    Takeshi Otowa
    Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Hum Genet 54:437-9. 2009
    ..No association of the Val66Met was consistent with two small studies in Japanese and Chinese populations. We therefore conclude that the BDNF polymorphism may not play a major role in PD in the East Asian populations...
  11. ncbi request reprint Temperament and melancholic type: path analysis of a prospective study of depressive mood change in a nonclinical population
    Yoshie Sakai
    Department of Psychiatry, Juntendo University School of Medicine, Koshigaya City, Japan
    Psychopathology 42:249-56. 2009
    ..Recent studies suggest that mood-disorder-related personality traits predict depressive mood changes (DMC) in nonclinical populations...
  12. ncbi request reprint Genome-wide association study of atypical psychosis
    Tetsufumi Kanazawa
    Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Osaka, Japan Department of Psychiatry, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan
    Am J Med Genet B Neuropsychiatr Genet 162:679-86. 2013
    ..01), but not BD. This study provides clues about the types of patient whose diagnosis lies between SZ and BD. Studies with larger samples are required to determine the causal variant...
  13. ncbi request reprint Reliability and validity of TEMPS-A in a Japanese non-clinical population: application to unipolar and bipolar depressives
    Satoko Matsumoto
    Department of Mental Health, School of Health Sciences, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Affect Disord 85:85-92. 2005
    ..In Japan, TEMPS-A has gathered much attention, because Kraepelin's concepts on "fundamental states" of mood disorder and temperaments have been widely respected...
  14. doi request reprint Association between the oxytocin receptor gene and amygdalar volume in healthy adults
    Hideyuki Inoue
    Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Biol Psychiatry 68:1066-72. 2010
    ..Genetic studies have revealed a link between the OXTR gene and the susceptibility to autism spectrum disorders (ASD), especially in the social dysfunctional feature of ASD...
  15. doi request reprint DNA methylation analysis of BDNF gene promoters in peripheral blood cells of schizophrenia patients
    Tempei Ikegame
    Department of Molecular Psychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neurosci Res 77:208-14. 2013
    ..Epigenetic alteration of BDNF in the PBC might reflect the pathophysiology of schizophrenia, and could be a potential biomarker. ..
  16. pmc Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia
    Seik Soon Khor
    Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Peerj 1:e66. 2013
    ..This is the first GWAS of HLA-DQB1*06:02 negative EHS, and the identification of these three new susceptibility loci should provide additional insights to the pathophysiological pathway of this condition...
  17. pmc Common variants on chromosome 9p21 are associated with normal tension glaucoma
    Mitsuko Takamoto
    Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    PLoS ONE 7:e40107. 2012
    ..Our results revealed that the 9p21 locus is also associated with NTG in Japanese. In addition, we identified SNPs more strongly associated with NTG...
  18. pmc Evidence for shared genetic risk between methamphetamine-induced psychosis and schizophrenia
    Masashi Ikeda
    Department of Psychiatry, Fujita Health University School of Medicine, Aichi, Japan
    Neuropsychopharmacology 38:1864-70. 2013
    ..These also suggest that the overlap between genes scored as positive in these data sets can have higher probability as susceptibility genes for psychosis...
  19. doi request reprint Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population
    Yukinori Okada
    Laboratory for Autoimmune Diseases, Center for Genomic Medicine, RIKEN, Yokohama, Japan
    Nat Genet 44:511-6. 2012
    ..This provided evidence of shared genetic risks of rheumatoid arthritis between the populations...
  20. ncbi request reprint [Cyclothymia and typus melancholicus: empirical study on personality character of mood disorder]
    Tsuyoshi Akiyama
    Department of Psychiatry, Kanto Medical Center NTT, Tokyo, Japan
    Seishin Shinkeigaku Zasshi 105:533-43. 2003
    ..5. To discuss the difference between monopolar and bipolar disorder in terms of personality character...