Yasuhiro Kawachi

Summary

Affiliation: University of Tsukuba
Country: Japan

Publications

  1. Kawachi Y, Ishitsuka Y, Maruyama H, Fujisawa Y, Furuta J, Nakamura Y, et al. GATA-3 regulates differentiation-specific loricrin gene expression in keratinocytes. Exp Dermatol. 2012;21:859-64 pubmed publisher
    ..These findings indicate that GATA-3 contributes to keratinocyte differentiation-specific activation of loricrin gene transcription via interaction with c-Fos and Sp1. ..
  2. Kawachi Y, Maruyama H, Ishitsuka Y, Fujisawa Y, Furuta J, Nakamura Y, et al. NF1 gene silencing induces upregulation of vascular endothelial growth factor expression in both Schwann and non-Schwann cells. Exp Dermatol. 2013;22:262-5 pubmed publisher
    ..We also showed that interleukin-6 is upregulated in Nf1 gene knock-down Schwann cells at the protein level. ..
  3. Kawachi Y, Xu X, Taguchi S, Sakurai H, Nakamura Y, Ishii Y, et al. Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice. J Invest Dermatol. 2008;128:1773-9 pubmed publisher
    ..Journal of Investigative Dermatology (2008) 128, 1773-1779; doi:10.1038/sj.jid.5701245; published online 17 January 2008. ..
  4. Kawachi Y, Ishitsuka Y, Maruyama H, Fujisawa Y, Furuta J, Nakamura Y, et al. The POU domain transcription factors Oct-6 and Oct-11 negatively regulate loricrin gene expression in keratinocytes: association with AP-1 and Sp1/Sp3. Arch Dermatol Res. 2013;305:371-8 pubmed publisher
    ..These findings indicate that Oct-6 and Oct-11 contribute to the regulation of loricrin gene transcription via interaction with AP-1 factors and Sp1/Sp3. ..
  5. Ishitsuka Y, Kawachi Y, Maruyama H, Taguchi S, Fujisawa Y, Furuta J, et al. Pituitary tumor transforming gene 1 induces tumor necrosis factor-? production from keratinocytes: implication for involvement in the pathophysiology of psoriasis. J Invest Dermatol. 2013;133:2566-2575 pubmed publisher
    ..Therefore, enhanced expression of PTTG1 in the psoriatic epidermis may result in aberrant regulation of the cell cycle and impaired differentiation via the interplay between PTTG1 and TNF-?. ..