K Kataoka

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint Block copolymer micelles for drug delivery: design, characterization and biological significance
    K Kataoka
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Adv Drug Deliv Rev 47:113-31. 2001
  2. doi request reprint Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis
    Md Rafi
    Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Control Release 159:189-96. 2012
  3. ncbi request reprint Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system
    N Nishiyama
    Department of Materials Science, Graduate School of Engineering, University of Tokyo, Japan
    Pharm Res 18:1035-41. 2001
  4. doi request reprint Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions
    H Kagaya
    Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Gene Ther 19:61-9. 2012
  5. ncbi request reprint Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core
    N Nishiyama
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    J Control Release 74:83-94. 2001
  6. doi request reprint Delivering the code: polyplex carriers for deoxyribonucleic acid and ribonucleic acid interference therapies
    R James Christie
    Department of Materials Engineering, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Endocrinology 151:466-73. 2010
  7. ncbi request reprint Sugar-installed block copolymer micelles: their preparation and specific interaction with lectin molecules
    Y Nagasaki
    Department of Materials Science, Science University of Tokyo, Noda 278-8510, Japan
    Biomacromolecules 2:1067-70. 2001
  8. ncbi request reprint Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge
    Y Yamamoto
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    J Control Release 77:27-38. 2001
  9. ncbi request reprint Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA
    Y Kakizawa
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    Biomacromolecules 2:491-7. 2001
  10. ncbi request reprint Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation
    D Akagi
    Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Gene Ther 14:1029-38. 2007

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Block copolymer micelles for drug delivery: design, characterization and biological significance
    K Kataoka
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Adv Drug Deliv Rev 47:113-31. 2001
    ..As an important perspective on carrier systems based on polymeric micelles, their feasibility as non-viral gene vectors is also summarized in this review article...
  2. doi request reprint Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis
    Md Rafi
    Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Control Release 159:189-96. 2012
    ..These results suggest DACHPt-loaded micelles as a promising nanocarrier for the treatment of scirrhous gastric cancers and their lymphatic metastases...
  3. ncbi request reprint Cisplatin-loaded polymer-metal complex micelle with time-modulated decaying property as a novel drug delivery system
    N Nishiyama
    Department of Materials Science, Graduate School of Engineering, University of Tokyo, Japan
    Pharm Res 18:1035-41. 2001
    ..Thus, CDDP-loaded micelles are expected to be a novel formulation of CDDP for clinical use...
  4. doi request reprint Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions
    H Kagaya
    Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Gene Ther 19:61-9. 2012
    ..These findings suggest that introduction of cRGD to polyplex micelles might create novel and useful functions for gene transfer and contribute to the establishment of efficient gene therapy for vascular diseases...
  5. ncbi request reprint Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiammineplatinum(II) in the core
    N Nishiyama
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    J Control Release 74:83-94. 2001
    ..These CDDP-loaded micelles are expected to have potential utility in tumor-directed delivery system of CDDP through the modulated in vivo biodisposition based on the EPR effect...
  6. doi request reprint Delivering the code: polyplex carriers for deoxyribonucleic acid and ribonucleic acid interference therapies
    R James Christie
    Department of Materials Engineering, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8656, Japan
    Endocrinology 151:466-73. 2010
    ..The most promising designs comprise features to help increase stability in circulation and also contain functionality to aid in endosome escape of nucleic acid cargo after cellular internalization...
  7. ncbi request reprint Sugar-installed block copolymer micelles: their preparation and specific interaction with lectin molecules
    Y Nagasaki
    Department of Materials Science, Science University of Tokyo, Noda 278-8510, Japan
    Biomacromolecules 2:1067-70. 2001
    ..With a lectin-immobilized affinity column, the cluster effect of the sugar molecule on the micelle surface was clearly observed...
  8. ncbi request reprint Long-circulating poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles with modulated surface charge
    Y Yamamoto
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    J Control Release 77:27-38. 2001
    ....
  9. ncbi request reprint Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA
    Y Kakizawa
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    Biomacromolecules 2:491-7. 2001
    ..On the other hand, the micelles dissociated to release ODN in the presence of GSH at a concentration comparable to the intracellular environment, featuring the potential ability of this system for intracellular ODN delivery...
  10. ncbi request reprint Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation
    D Akagi
    Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Gene Ther 14:1029-38. 2007
    ..These findings suggest that the PEG-b-P[Asp(DET)] polyplex micelle may have promising potential as a nonviral vector for the treatment of vascular diseases...
  11. ncbi request reprint Pronounced activity of enzymes through the incorporation into the core of polyion complex micelles made from charged block copolymers
    A Harada
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
    J Control Release 72:85-91. 2001
    ..This type of PIC micelle system entrapping enzyme in the core might be useful for the design of diagnostic as well as targetable therapeutic systems of enzyme including antibody-directed enzyme prodrug therapy (ADEPT)...
  12. ncbi request reprint Novel ternary polyplex of triblock copolymer, pDNA and anionic dendrimer phthalocyanine for photochemical enhancement of transgene expression
    A Arnida
    Department of Materials Science and Engineering, Graduate School of Engineering, The University of Tokyo, Hongo, Bunkyo ku, Tokyo, Japan
    J Control Release 116:e75-7. 2006
  13. doi request reprint Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
    H Cabral
    Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Hongo, Bunkyo ku, Japan
    Nat Nanotechnol 6:815-23. 2011
    ..We also showed that the penetration and efficacy of the larger micelles could be enhanced by using a transforming growth factor-β inhibitor to increase the permeability of the tumours...
  14. ncbi request reprint Physicochemical properties and nuclease resistance of antisense-oligodeoxynucleotides entrapped in the core of polyion complex micelles composed of poly(ethylene glycol)-poly(L-lysine) block copolymers
    A Harada
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8656, Tokyo, Japan
    Eur J Pharm Sci 13:35-42. 2001
    ..These characteristics of the PIC micelle system highlight its promising feature as ODN carrier used in the field of targeting therapy...
  15. ncbi request reprint Quantitative and reversible lectin-induced association of gold nanoparticles modified with alpha-lactosyl-omega-mercapto-poly(ethylene glycol)
    H Otsuka
    Department of Materials Science, Graduate School of Engineering, The University of Tokyo, Hongo 7-3-1, Tokyo 113-8656, Japan
    J Am Chem Soc 123:8226-30. 2001
    ..This simple, yet highly effective, derivatization of gold nanoparticles with heterobifunctional PEG provides a convenient method to construct various colloidal sensor systems currently applied in bioassays and biorecognition...
  16. ncbi request reprint Significant enhancement of antitumor activity and bioavailability of intracellular pH-sensitive polymeric micelles by folate conjugation
    Y Bae
    Division of Clinical Biotechnology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo ku, Tokyo, Japan
    J Control Release 116:e49-50. 2006
  17. ncbi request reprint Ligand-installed PEGylated bionanosphere
    Y Nagasaki
    Department of Materials Science, Tokyo University of Science, Noda 278 8510, Japan
    IEE Proc Nanobiotechnol 152:89-96. 2005
    ..This FRET system using the PEGylated CdS QD coupled with fluorescent-labelled protein can be utilised as a highly sensitive bioanalytical system...
  18. ncbi request reprint Polyion complex micelles as vectors in gene therapy--pharmacokinetics and in vivo gene transfer
    M Harada-Shiba
    National Cardiovascular Center Research Institute, Osaka, Japan
    Gene Ther 9:407-14. 2002
    ..When the PIC micelles were injected via supramesenteric vein, expression of the gene was observed only in the liver and was sustained for 3 days. It was suggested that this gene delivery system is intrinsically efficient...
  19. ncbi request reprint Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity
    Y Mizumura
    Department of Medicine, National Cancer Center Hospital, Chuo-ku, Tokyo 104-0045, Japan
    Jpn J Cancer Res 92:328-36. 2001
    ..CDDP / m treatment caused much less renal damage than CDDP. These results indicate that CDDP / m treatment can reduce CDDP-induced nephrotoxicity without compromising the anticancer cytotoxicity of CDDP...
  20. ncbi request reprint Survivin inhibits apoptosis in cytotrophoblasts
    A Shiozaki
    Department of Obstetrics and Gynecology, Health Insurance Takaoka Hospital, Japan
    Placenta 24:65-76. 2003
    ..These findings suggest that survivin antagonizes apoptosis in cytotrophoblasts, extravillous trophoblasts, and choriocarcinoma cells...
  21. ncbi request reprint Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
    K Igarashi
    Department of Biochemistry, Tohoku University School of Medicine, Sendai, Japan
    Nature 367:568-72. 1994
    ....
  22. ncbi request reprint Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain
    K T Fujiwara
    Department of Viral Oncology, Cancer Institute, Tokyo, Japan
    Oncogene 8:2371-80. 1993
    ..Tissue distributions of these three maf-family genes are different from one another, probably reflecting their different functions in vivo...
  23. ncbi request reprint A carcinoembryonic antigen family cDNA from mouse placenta encoding a protein with a rare domain composition
    K Kataoka
    Department of Biochemistry, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama shi, 930 0194, Japan
    Placenta 21:610-4. 2000
    ..Except for in the placenta, Ceacam11 transcripts were not detected in any adult tissues examined, including brain, lung, glandular stomach, small intestine, colon, liver, kidney and testis...
  24. doi request reprint Metastatic brain tumor surgery using fluorescein sodium: technical note
    T Okuda
    Department of Neurosurgery, Kinki University School of Medicine, Osaka, Japan
    Minim Invasive Neurosurg 50:382-4. 2007
    ..Fluorescein sodium is inexpensive, highly safe, and comparatively easy to use, and does not require any special equipment. We believe that the use of fluorescein sodium is beneficial for resection of the metastatic brain tumor...
  25. ncbi request reprint A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities
    K Kataoka
    Department of Virology, Institute of Medical Science, University of Tokyo, 4 6 1 Shirokanedai, Minato ku 108 8639, Tokyo, Japan
    J Biol Chem 276:819-26. 2001
    ..These results suggested that the interaction of a set of Hox proteins with Maf family members may interfere not only with their oncogenicity but also with their physiological roles...
  26. ncbi request reprint Cloning of the hamster androgen receptor gene
    K Shiba
    Department of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan
    J Dermatol Sci 26:163-8. 2001
    ..Availability of the recombinant hamAR clone along with the flank organ system should provide a more powerful tool than currently available to investigate androgen action at the molecular level...
  27. pmc Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery
    I A Khalil
    Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan
    Gene Ther 14:682-9. 2007
    ..These data demonstrate that MEND is a promising non-viral gene delivery system that may provide superior results to existing non-viral gene delivery technologies...
  28. ncbi request reprint Prevention of abdominal aortic aneurysms by simultaneous inhibition of NFkappaB and ets using chimeric decoy oligonucleotides in a rabbit model
    T Miyake
    Division of Clinical Gene Therapy, Graduate School of Medicine, Osaka University, Suita, Osaka 565 0871, Japan
    Gene Ther 13:695-704. 2006
    ..Further modification of chimeric decoy ODN would be useful to treat AAA as a decoy-based therapy...
  29. pmc Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats
    H Uchino
    Investigative Treatment Division, National Cancer Center Research Institute East, 6 5 1 Kashiwanoha, Kashiwa, Chiba 277 8577, Japan
    Br J Cancer 93:678-87. 2005
    ....
  30. ncbi request reprint Novel collagen sponge reinforced with polyglycolic acid fiber produces robust, normal hair in murine hair reconstitution model
    M Itoh
    Department of Tissue Regeneration, Research Institute, International Medical Center of Japan, Tokyo, Japan
    Tissue Eng 10:818-24. 2004
    ..These data suggested the usefulness of PGA fiber-containing collagen sponges for hair reconstitution in research and clinical applications...
  31. ncbi request reprint Activation of the phosphatidylinositol-3' kinase pathway and DNA synthesis by a mutant insulin-like growth factor I receptor lacking the NPXY motif
    K Kataoka
    Molecular Diagnosis and Therapeutics, Department of Oral Restitution, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8549, Japan
    J Endocrinol 181:139-46. 2004
    ..These results indicate that the IGF-IR is able to activate the PI3-K pathway and induce DNA synthesis in a normal fashion without the NPXY motif when the receptor is fully activated...
  32. ncbi request reprint Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells
    K Kataoka
    Laboratory of Molecular and Developmental Biology, Graduate School of Biological Science, Nara Institute of Science and Technology, 8916 5 Takayama cho, Ikoma 630 0192, Japan
    J Mol Endocrinol 32:9-20. 2004
    ..Thus, c-Maf and MafA are differentially expressed in alpha- and beta-cells where they regulate glucagon and insulin gene expression, respectively...
  33. pmc MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun
    K Kataoka
    Department of Viral Oncology, Cancer Institute, Tokyo, Japan
    Mol Cell Biol 14:7581-91. 1994
    ..Through formation of numerous bZip dimers, the Maf family proteins along with the AP-1 components should provide great diversity in transcriptional regulation for a wide variety of genes...