Yoshiakira Kanai


Affiliation: University of Tokyo
Country: Japan


  1. request reprint
    Kanai Y, Hiramatsu R, Matoba S, Kidokoro T. From SRY to SOX9: mammalian testis differentiation. J Biochem. 2005;138:13-9 pubmed
    ..This paper mainly focuses on recent advances in elucidating the regulatory mechanisms of Sry and Sox9 expression and male-specific cellular events immediately downstream of SRY action during the initial phases of testis differentiation. ..
  2. request reprint
    Kanai Y, Kanai Azuma M, Tajima Y, Birk O, Hayashi Y, Sanai Y. Identification of a stromal cell type characterized by the secretion of a soluble integrin-binding protein, MFG-E8, in mouse early gonadogenesis. Mech Dev. 2000;96:223-7 pubmed
    ..5-day testes revealed that the Mfge8-positive cells constitute a previously uncharacterized somatic cell type which is distinct from Sertoli cells, Leydig cells, peritubular myoid cells and the endothelial cells. ..
  3. Shinomura M, Kishi K, Tomita A, Kawasumi M, Kanezashi H, Kuroda Y, et al. A novel Amh-Treck transgenic mouse line allows toxin-dependent loss of supporting cells in gonads. Reproduction. 2014;148:H1-9 pubmed publisher
  4. Uchida A, Kishi K, Aiyama Y, Miura K, Takase H, Suzuki H, et al. In vivo dynamics of GFR?1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay. Biochem Biophys Res Commun. 2016;476:546-552 pubmed publisher
  5. Higashiyama H, Ozawa A, Sumitomo H, Uemura M, Fujino K, Igarashi H, et al. Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia. Development. 2017;144:1906-1917 pubmed publisher
  6. Kishi K, Uchida A, Takase H, Suzuki H, Kurohmaru M, Tsunekawa N, et al. Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice. Reproduction. 2017;154:135-143 pubmed publisher
    ..These data provide the first evidence of the crucial role of the spermatogonial USP9X during transition from the mitotic to meiotic phases and/or maintenance of early meiotic phase in Usp9x conditional knockout testes. ..