Shinji Kagami

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi Treatment of persistent Mongolian spots with Q-switched alexandrite laser
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Lasers Med Sci 27:1229-32. 2012
  2. ncbi A probable case of Muckle-Wells syndrome
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Dermatol 33:118-21. 2006
  3. ncbi CCL28 production in HaCaT cells was mediated by different signal pathways from CCL27
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan
    Exp Dermatol 15:95-100. 2006
  4. ncbi Treatment of 153 Japanese patients with Q-switched alexandrite laser
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Lasers Med Sci 22:159-63. 2007
  5. ncbi CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Eur J Immunol 38:647-57. 2008
  6. ncbi Interleukin-4 and interleukin-13 enhance CCL26 production in a human keratinocyte cell line, HaCaT cells
    S Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Immunol 141:459-66. 2005
  7. ncbi Laser treatment of 26 Japanese patients with Mongolian spots
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Dermatol Surg 34:1689-94. 2008
  8. ncbi Significant elevation of serum levels of eotaxin-3/CCL26, but not of eotaxin-2/CCL24, in patients with atopic dermatitis: serum eotaxin-3/CCL26 levels reflect the disease activity of atopic dermatitis
    S Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Immunol 134:309-13. 2003
  9. ncbi The -431C>T polymorphism of thymus and activation-regulated chemokine increases the promoter activity but is not associated with susceptibility to atopic dermatitis in Japanese patients
    Yuichiro Tsunemi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Exp Dermatol 13:715-9. 2004
  10. ncbi CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli
    Yuichiro Tsunemi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Eur J Immunol 36:2116-27. 2006

Collaborators

Detail Information

Publications23

  1. ncbi Treatment of persistent Mongolian spots with Q-switched alexandrite laser
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, Japan
    Lasers Med Sci 27:1229-32. 2012
    ....
  2. ncbi A probable case of Muckle-Wells syndrome
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Dermatol 33:118-21. 2006
    ..Therefore, we should consider the possibility of periodic fever syndrome when we see patients with refractory urticaria and episodic fever...
  3. ncbi CCL28 production in HaCaT cells was mediated by different signal pathways from CCL27
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan
    Exp Dermatol 15:95-100. 2006
    ..Our study results suggest that CCL28 produced by keratinocytes is mediated by different signal pathways from CCL27 and that both CCL27 and CCL28 are involved in the pathogenesis of inflammatory skin diseases...
  4. ncbi Treatment of 153 Japanese patients with Q-switched alexandrite laser
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Lasers Med Sci 22:159-63. 2007
    ..As a whole, good therapeutic outcome was achieved after multiple treatment sessions. However, the use of other lasers or other treatment modalities should be considered to treat nevus spilus/café-au-lait spots...
  5. ncbi CCL27-transgenic mice show enhanced contact hypersensitivity to Th2, but not Th1 stimuli
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Eur J Immunol 38:647-57. 2008
    ..These results indicated that CCL27 modified inflammation by attracting CCR10-positive and CCR4-positive cells into the lesional skin, and may participate in the pathogenesis of Th2-shifted skin diseases such as atopic dermatitis...
  6. ncbi Interleukin-4 and interleukin-13 enhance CCL26 production in a human keratinocyte cell line, HaCaT cells
    S Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Immunol 141:459-66. 2005
    ..These results suggest that keratinocytes are involved in the migration of CC chemokine receptor 3 positive cells such as eosinophils in a Th2-dominant situation like atopic dermatitis...
  7. ncbi Laser treatment of 26 Japanese patients with Mongolian spots
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Dermatol Surg 34:1689-94. 2008
    ..They are found most frequently in the sacral region and typically disappear during childhood. Occasionally, they persist to adulthood...
  8. ncbi Significant elevation of serum levels of eotaxin-3/CCL26, but not of eotaxin-2/CCL24, in patients with atopic dermatitis: serum eotaxin-3/CCL26 levels reflect the disease activity of atopic dermatitis
    S Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Clin Exp Immunol 134:309-13. 2003
    ....
  9. ncbi The -431C>T polymorphism of thymus and activation-regulated chemokine increases the promoter activity but is not associated with susceptibility to atopic dermatitis in Japanese patients
    Yuichiro Tsunemi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Exp Dermatol 13:715-9. 2004
    ..Thymus and activation-regulated chemokine (TARC) plays an important role in the pathogenesis of atopic dermatitis (AD). We recently detected the single nucleotide polymorphism (SNP) (-431C>T) in the 5'-flanking region of TARC gene...
  10. ncbi CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuli
    Yuichiro Tsunemi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Eur J Immunol 36:2116-27. 2006
    ..AD-like conditions such as increased number of mast cells and elevated levels of serum IgE were observed. Thus, CCL17 may participate in the pathogenesis of skin diseases such as AD by regulating both allergic and irritant inflammation...
  11. ncbi Both IL-4 and IL-13 inhibit the TNF-alpha and IFN-gamma enhanced MDC production in a human keratinocyte cell line, HaCaT cells
    Ting Xiao
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-8655, Tokyo, Japan
    J Dermatol Sci 31:111-7. 2003
    ..CONCLUSION: Th2-type cytokines IL-4 and IL-13 downregulate the production of MDC, a Th2 type chemokine, by KCs. This may partially contribute to maintaining Th1/Th2 balance in inflammatory skin diseases like atopic dermatitis...
  12. ncbi Histamine differentially regulates the production of Th1 and Th2 chemokines by keratinocytes through histamine H1 receptor
    Seiki Fujimoto
    Department of Dermatology, University of Tokyo, Tokyo, Japan
    Cytokine 54:191-9. 2011
    ....
  13. ncbi Mechanism of thymus- and activation-regulated chemokine (TARC)/CCL17 production and its modulation by roxithromycin
    Mayumi Komine
    Department of Dermatology, University of Tokyo, Tokyo, Japan
    J Invest Dermatol 125:491-8. 2005
    ..Through elucidating the mechanism of CCL17 production, our study indicates that RXM suppresses the production through the inhibition of p38 and NFkappaB, independent of the inhibition of IkappaB degradation...
  14. ncbi CCR4 and CCR10 are expressed on epidermal keratinocytes and are involved in cutaneous immune reaction
    Seiki Fujimoto
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Cytokine 44:172-8. 2008
    ..Thus this study provided new insight into chemokine/chemokine receptors of KCs...
  15. ncbi Lack of association of CCR4 single nucleotide polymorphism with atopic dermatitis in Japanese patients
    Yuichiro Tsunemi
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan
    Acta Derm Venereol 84:187-90. 2004
    ..C1014T SNP of CCR4 does not appear to be associated with susceptibility to atopic dermatitis in Japanese patients...
  16. ncbi Evaluation of the treatment of port-wine stains with the 595-nm long pulsed dye laser: a large prospective study in adult Japanese patients
    Akihiko Asahina
    Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    J Am Acad Dermatol 54:487-93. 2006
    ..Treatments of port-wine stains with conventional pulsed dye laser yield inconsistent results...
  17. ncbi Association of nerve growth factor, chemokine (C-C motif) ligands and immunoglobulin E with pruritus in cutaneous T-cell lymphoma
    Hiraku Suga
    Department of Dermatology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Tokyo, Japan
    Acta Derm Venereol 93:144-9. 2013
    ..NGF may be associated with increased dermal nerve fibres and pruritus in Sézary syndrome, and CCL1, CCL26, and IgE may be associated with pruritus in CTCL...
  18. ncbi Epithelioid sarcoma associated with lung adenocarcinoma
    Shinji Kagami
    Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan
    J Dermatol 32:904-8. 2005
    ..The size of the ulcer and the tumor invasion along the fasciae of muscles were decreased, however, metastasis of the epithelioid sarcoma was detected in the lymph node of the left axilla four years after the diagnosis...
  19. ncbi [IL-23 and Th17 cells in infections and psoriasis]
    Shinji Kagami
    Department of Dermatology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Nihon Rinsho Meneki Gakkai Kaishi 34:13-9. 2011
    ....
  20. ncbi Increased serum CCL28 levels in patients with atopic dermatitis, psoriasis vulgaris and bullous pemphigoid
    Shinji Kagami
    J Invest Dermatol 124:1088-90. 2005
  21. ncbi Prevalence of atopic dermatitis determined by clinical examination in Japanese adults
    Hidehisa Saeki
    J Dermatol 33:817-9. 2006
  22. ncbi Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients
    Megumu Saito
    Departments of Pediatrics, Kyoto University Graduate School of Medicine, Shogoin, Sakyo ku, Kyoto, Japan
    Blood 111:2132-41. 2008
    ..Our findings reveal a novel effect of CIAS1 mutations in promoting necrosis-like cell death, and demonstrate that CIAS1 mosaicism plays an important role in mutation-negative CAPS patients...
  23. ncbi Elevated serum CTACK/CCL27 levels in CTCL
    Shinji Kagami
    J Invest Dermatol 126:1189-91. 2006