Makoto Ishikawa

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint Expression of vascular endothelial growth factor C and D (VEGF-C and -D) is an important risk factor for lymphatic metastasis in undifferentiated early gastric carcinoma
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Jpn J Clin Oncol 33:21-7. 2003
  2. ncbi request reprint Prospective randomized trial comparing Billroth I and Roux-en-Y procedures after distal gastrectomy for gastric carcinoma
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, 7 3 1 Hongo, Bankyo ku, Tokyo 113 8655, Japan
    World J Surg 29:1415-20; discussion 1421. 2005
  3. ncbi request reprint The expression pattern of UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetyl-galactosaminyl transferase-3 in squamous cell carcinoma of the esophagus
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Pathobiology 72:139-45. 2005
  4. ncbi request reprint Plasma adiponectin and gastric cancer
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Cancer Res 11:466-72. 2005
  5. ncbi request reprint Diagnosis of nasopharyngeal carcinoma metastatic to mediastinal lymph nodes by endoscopic ultrasonography-guided fine-needle aspiration biopsy
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Acta Otolaryngol 125:1014-7. 2005
  6. ncbi request reprint The expression pattern of vascular endothelial growth factor C and D in human esophageal normal mucosa, dysplasia and neoplasia
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Hepatogastroenterology 51:1319-22. 2004
  7. ncbi request reprint Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Clin Cancer Res 10:4325-31. 2004
  8. ncbi request reprint The expression pattern of UDP-N-acetyl-alpha-d-galactosamine: polypeptide N-acetylgalactosaminyl transferase-3 in early gastric carcinoma
    Makoto Ishikawa
    Department of Surgery, The University of Tokyo, Japan
    J Surg Oncol 86:28-33. 2004
  9. ncbi request reprint Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer
    Makoto Ishikawa
    Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    World J Gastroenterol 12:5517-22. 2006
  10. ncbi request reprint Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer
    Hiroharu Yamashita
    Department of Surgical Oncology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    J Surg Oncol 93:30-5. 2006

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Expression of vascular endothelial growth factor C and D (VEGF-C and -D) is an important risk factor for lymphatic metastasis in undifferentiated early gastric carcinoma
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Jpn J Clin Oncol 33:21-7. 2003
    ..In this study, we aimed to clarify the relation between expression of VEGF-C and -D and lymphatic metastasis in early gastric cancers...
  2. ncbi request reprint Prospective randomized trial comparing Billroth I and Roux-en-Y procedures after distal gastrectomy for gastric carcinoma
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, 7 3 1 Hongo, Bankyo ku, Tokyo 113 8655, Japan
    World J Surg 29:1415-20; discussion 1421. 2005
    ..Because RY reconstruction induces the frequent complication of Roux-en-Y stasis, causing longer postoperative hospital stay, this method has limited advantages over B-I anastomosis after distal gastrectomy...
  3. ncbi request reprint The expression pattern of UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetyl-galactosaminyl transferase-3 in squamous cell carcinoma of the esophagus
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Pathobiology 72:139-45. 2005
    ..Although a different expression of GalNAc-T3 has been reported in various cancers, the expression has not been characterized in squamous cell carcinoma (SCC) of the esophagus...
  4. ncbi request reprint Plasma adiponectin and gastric cancer
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Cancer Res 11:466-72. 2005
    ..Moreover, the circulating level of adiponectin has been reported to be inversely related to body mass index...
  5. ncbi request reprint Diagnosis of nasopharyngeal carcinoma metastatic to mediastinal lymph nodes by endoscopic ultrasonography-guided fine-needle aspiration biopsy
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Acta Otolaryngol 125:1014-7. 2005
    ..In conclusion, EUS-FNA is a safe and reliable technique for evaluation of mediastinal lymphadenopathy, and is especially valuable for head and neck tumors with suspected metastasis...
  6. ncbi request reprint The expression pattern of vascular endothelial growth factor C and D in human esophageal normal mucosa, dysplasia and neoplasia
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Hepatogastroenterology 51:1319-22. 2004
    ..In this study, we examined the expression of VEGF-C and -D in esophageal carcinoma...
  7. ncbi request reprint Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Clin Cancer Res 10:4325-31. 2004
    ..To evaluate leptin and leptin receptor (OB-R) expression in human breast cancer and determine whether it could be effective for the prevention and treatment of breast cancer...
  8. ncbi request reprint The expression pattern of UDP-N-acetyl-alpha-d-galactosamine: polypeptide N-acetylgalactosaminyl transferase-3 in early gastric carcinoma
    Makoto Ishikawa
    Department of Surgery, The University of Tokyo, Japan
    J Surg Oncol 86:28-33. 2004
    ..Although the expression of GalNAc-T3 has been examined in various cancers, the expression has not been characterized in early stages of cancer...
  9. ncbi request reprint Expression pattern of leptin and leptin receptor (OB-R) in human gastric cancer
    Makoto Ishikawa
    Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    World J Gastroenterol 12:5517-22. 2006
    ..To examine the expression of leptin and its receptor, OB-R, in normal gastric mucosa and neoplasia...
  10. ncbi request reprint Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer
    Hiroharu Yamashita
    Department of Surgical Oncology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    J Surg Oncol 93:30-5. 2006
    ..Recently, it was reported that malignant transformation resulted in aberrant expression of LPA2 in a various type of cancer, suggesting the positive role of LPA2 in tumor development...
  11. ncbi request reprint Impact of immunohistochemically identified lymphatic invasion on nodal metastasis in early gastric cancer
    Akihiro Sako
    Department of Surgical Oncology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Gastric Cancer 9:295-302. 2006
    ..However, the diagnosis of Ly is subjective and often inaccurate because of the difficulty of detecting lymphatic vessels with conventional hematoxylin and eosin (HE) staining...
  12. ncbi request reprint Tissue factor expression is a clinical indicator of lymphatic metastasis and poor prognosis in gastric cancer with intestinal phenotype
    Hiroharu Yamashita
    Department of Surgical Oncology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    J Surg Oncol 95:324-31. 2007
    ..Aberrantly expressed TF in cancer cells has been reported to be associated with advanced stages of malignancy in various cancers...
  13. ncbi request reprint Recurrent intramucosal gastric carcinoma with extensive invasion to duodenal mucosa after endoscopic mucosal resection: a case report
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Am Surg 71:366-8. 2005
    ..We report an unusual case of an intramucosal gastric carcinoma with extensive duodenal invasion that was preoperatively diagnosed by endoscopy...
  14. doi request reprint Leptin augments proliferation of breast cancer cells via transactivation of HER2
    Daisuke Soma
    Department of Surgery, Division of Surgical Oncology, University of Tokyo, Tokyo, Japan
    J Surg Res 149:9-14. 2008
    ..Collectively, our data suggest that leptin can transactivate HER2 through both epidermal growth factor receptor and Janus-activated kinase 2 activation, which can cause the growth of breast cancer cells with HER2 overexpression...
  15. ncbi request reprint Hyaluronic acid is a useful tool for intraoperative sentinel node detection in gastric cancer surgery
    Joji Kitayama
    Department of Surgical Oncology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Surgery 141:815-20. 2007
    ..Because dyes are carried out from the SN within 20 to 30 minutes, it is sometimes difficult to detect SNs accurately, especially when they are located in a deep area in obese patients...
  16. ncbi request reprint Complete coverage of in situ aortograft by total omental pedicle flap as the most reliable treatment of aortoesophageal fistula
    Joji Kitayama
    Department of Surgical Oncology, University of Tokyo, Hongo 7 3 1, Bunkyo ku, Tokyo 113 0033, Japan
    Am J Surg 192:130-4. 2006
    ..Thus, our omental coverage appears to be the most reliable method to prevent postoperative graft infection...
  17. ncbi request reprint Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2
    Makoto Ishikawa
    Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Cancer Sci 98:1120-7. 2007
    ..Although adiponectin was already reported to have antiangiogenic effects, our results suggest that the antitumor effect of adiponectin was, at least partially, dependent on the direct effects on tumor cells...
  18. doi request reprint Adiposity and gastrointestinal malignancy
    Joji Kitayama
    Department of Surgical Oncology, University of Tokyo, Tokyo, Japan
    Digestion 79:26-32. 2009
    ..In early gastric cancer, patients with undifferentiated type have lower fat volume than those with differentiated type. Adiposity appears to be closely related with various aspects in pathophysiology of gastrointestinal malignancy...
  19. pmc Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma
    Joji Kitayama
    Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Breast Cancer Res 6:R640-6. 2004
    ..In the present study we characterized the expression profile of LPA receptors in human breast cancer tissue and assessed the possible roles of each receptor...
  20. ncbi request reprint Occult breast cancer presenting as axillary metastases
    Hironori Yamaguchi
    The Department of Surgery, Kanto Rosai Hospital, 2035 Kizukisumiyoshi cho Nakahara ku Kawasaki shi Kanagawa 211 8510, Japan
    Breast 15:259-62. 2006
    ..Pathology revealed an invasive ductal carcinoma (1.5x1 mm in size) with extensive lymphatic involvement, which strongly expressed both vascular endothelial growth factor-C (VEGF-C) and VEGF-D...
  21. ncbi request reprint Image of the month: left gastric aneurysm
    Makoto Ishikawa
    Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
    Gastroenterology 130:7, 288. 2006
  22. doi request reprint Has laparoscopic bariatric surgery been accepted in Japan? The experience of a single surgeon
    Kazunori Kasama
    Minimally Invasive Surgery Center, Yotsuya Medical Cube, 2 7 7 Niban cho, Chiyoda ku, Tokyo, 102 0084, Japan
    Obes Surg 18:1473-8. 2008
    ..There are no adequate data regarding the experience and outcome of bariatric surgery in Asia. Here, we report on the current status of morbid obesity and the outcomes of bariatric surgery by a single surgeon in Japan...
  23. doi request reprint Serum p53 antibodies as a prognostic indicator in oral squamous cell carcinoma
    Yutaka Yamazaki
    Oral Diagnosis and Medicine, Graduate School of Dental Medicine, Hokkaido University, Kita 13 Nishi 7, Kita ku, Sapporo, 060 8586, Japan
    Odontology 96:32-7. 2008
    ..Therefore, the detection of p53 Abs in the serum of patients with SCC may be a useful prognostic marker...
  24. ncbi request reprint Wistar rat palpebral conjunctiva contains more slow-cycling stem cells that have larger proliferative capacity: implication for conjunctival epithelial homeostasis
    Wensheng Chen
    Department of Ophthalmology, Akita University School of Medicine, Akita, Japan
    Jpn J Ophthalmol 47:119-28. 2003
    ..To determine the location of conjunctival epithelial stem cells...
  25. ncbi request reprint Restenosis and stent fracture following sirolimus-eluting stent (SES) implantation
    Masanori Okumura
    Division of Cardiology, Fujita Health University Hospital, Toyoake, Japan
    Circ J 71:1669-77. 2007
    ..Restenosis still occurs, even with the sirolimus-eluting stent (SES), and the precise mechanisms and the impact of stent fracture on restensosis have not yet been elucidated...