Research Topics
Species | S IinoSummaryAffiliation: University of Fukui Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Interstitial cells of Cajal in the gastrointestinal musculature of W(jic) c-kit mutant miceSatoshi Iino
Department of Morphological and Physiological Sciences, University of Fukui, Japan
J Smooth Muscle Res 47:111-21. 2011..From these findings, we conclude that W(jic)/W(jic) mice represent a distinct, novel genotype resulting in a lack of a specific type of ICC in the gastrointestinal musculature...- Immunohistochemical demonstration of c-Kit-negative fibroblast-like cells in murine gastrointestinal musculatureSatoshi Iino
Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, Eiheiji, Fukui, Japan
Arch Histol Cytol 72:107-15. 2009..Thus, our observations indicate that SK3- and PDGFRalpha-double immunopositive cells are FLC in the murine gastrointestinal musculature and behave as a basic cellular element throughout the gastrointestinal musculature... 
W(sh)/W(sh) c-Kit mutant mice possess interstitial cells of Cajal in the deep muscular plexus layer of the small intestineSatoshi Iino
Department of Morphological and Physiological Sciences, University of Fukui, Faculty of Medical Sciences, Matsuoka, Eiheiji, Fukui 910 1193, Japan
Neurosci Lett 459:123-6. 2009..This type of ICC may develop and maturate structurally without c-Kit expression and regulate gastrointestinal motility...- c-Kit-negative fibroblast-like cells express platelet-derived growth factor receptor alpha in the murine gastrointestinal musculatureSatoshi Iino
Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, Eiheiji, Fukui 910 1193, Japan
Histochem Cell Biol 131:691-702. 2009..Our observations suggest that PDGFRalpha-ip cells are basic cellular elements throughout the gastrointestinal musculature and are involved in the gastrointestinal functions... - Interstitial cells of Cajal contain signalling molecules for transduction of nitrergic stimulation in guinea pig caecumS Iino
Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, Eiheiji, Fukui, Japan
Neurogastroenterol Motil 21:542-50, e12-3. 2009..These data show that ICC express the downstream signalling molecules necessary to transduce nitrergic signals and activate inhibitory pathways and thus are primary targets for NO released from neurons and other cells in the GI tract... - Interstitial cells of Cajal are innervated by nitrergic nerves and express nitric oxide-sensitive guanylate cyclase in the guinea-pig gastrointestinal tractS Iino
Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, Eiheiji, Fukui 910 1193, Japan
Neuroscience 152:437-48. 2008..These data suggest that ICC are primary targets for NO released from nNOS-containing enteric neurons, and that some NO signals are received by FLC and smooth muscle cells in the gastrointestinal tract... - Interstitial cells of Cajal in the gastrointestinal musculature of W mutant miceSatoshi Iino
Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, Fukui, Japan
Arch Histol Cytol 70:163-73. 2007..The enteric nervous system of the two mutant mice showed normal characteristics. From these findings, we conclude that W( v)/W( v) mice represent a new genotype that lacks a part of the ICC in its gastrointestinal musculature... - Muscular innervation of the proximal duodenum of the guinea pigS Iino
Department of Anatomy, Fukui Medical University, Matsuoka, Japan
Arch Histol Cytol 63:327-43. 2000..The functional significance of the proximal duodenum in relation to the electrical connection and neural cooperation of the musculature between the antrum and the duodenum is also discussed... - Muscarinic M(2) acetylcholine receptor distribution in the guinea-pig gastrointestinal tractS Iino
Department of Anatomy, University of Fukui Faculty of Medical Sciences, Matsuoka, Fukui 910 1193 Japan
Neuroscience 138:549-59. 2006.... - Gamma-aminobutyric acid-containing sympathetic preganglionic neurons in rat thoracic spinal cord send their axons to the superior cervical ganglionTetsufumi Ito
Department of Anatomy, Faculty of Medical Sciences, University of Fukui, Fukui 910 1193, Japan
J Comp Neurol 502:113-25. 2007..Thus, the present findings strongly indicate that some sympathetic preganglionic neurons are not only cholinergic but also GABAegic... - Some gamma-motoneurons contain gamma-aminobutyric acid in the rat cervical spinal cordTetsufumi Ito
Department of Anatomy, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki, Fukui 910 1193, Japan
Brain Res 1201:78-87. 2008..Since we detected neither GABAA nor GABAB receptors in the TBM by RT-PCR, the function of the GABA-containing gamma-motoneurons remains unclear... - Heterogeneous distribution of a gap junction protein, connexin43, in the gastroduodenal junction of the guinea pigS Iino
Department of Anatomy, Fukui Medical University, Matsuoka, Japan
Auton Neurosci 93:8-13. 2001..The results suggest that the gastroduodenal junction has heterogeneous electrical connections among smooth muscle cells via gap junctions, and specific nerve innervation, which regulates gastroduodenal motility... - Downregulation of msh-like 2 (msx2) and neurotrophic tyrosine kinase receptor type 2 (ntrk2) in the developmental gut of KIT mutant miceSatomi Horiguchi
Division of Anatomy and Neuroscience, Department of Morphological and Physiological Sciences, University of Fukui Faculty of Medical Sciences, Eiheiji cho, Matsuoka Shimoaizuki 23 3, Fukui 910 1193, Japan
Biochem Biophys Res Commun 396:774-9. 2010..These data suggest that the gene expressions of ntrk2 and msx2 were significantly suppressed in KIT mutant mouse embryo and neonate and that these genes are likely to regulate ICC development... - A part of cholinergic fibers in mouse superior cervical ganglia contain GABA or glutamateTetsufumi Ito
Department of Anatomy, Faculty of Medical Sciences, University of Fukui, Japan
Brain Res 1046:234-8. 2005..The origin of these fibers was discussed... - Motor, sensory and autonomic nerve terminals containing NAP-22 immunoreactivity in the rat muscleSatoshi Iino
Department of Anatomy, University of Fukui Faculty of Medical Science, Matsuoka, Fukui 910 1193, Japan
Brain Res 1002:142-50. 2004..These findings suggest that NAP-22 is distributed and regulates functions in the motor, sensory and autonomic nerve terminals in the peripheral nervous system... - Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosisKamal Krishna Biswas
Department of Laboratory and Molecular Medicine, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
Hepatology 38:1167-77. 2003..In conclusion, our data suggest that cholesterol present in the cell membrane determines the fate of hepatocytes exposed to anandamide, possibly functioning as an anandamide receptor... 
Interstitial cells of Cajal are functionally innervated by excitatory motor neurones in the murine intestineSatoshi Iino
Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557, USA
J Physiol 556:521-30. 2004..These data suggest that ICC-DMP are primary targets for neurokinins released from enteric motor neurones in the intestine...