Research Topics
Genomes and GenesSpecies | Atsushi HozawaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Publications
Relationship between serum isoflavone levels and disability-free survival among community-dwelling elderly individuals: nested case-control study of the Tsurugaya projectAtsushi Hozawa
Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai 980 8573, Japan
J Gerontol A Biol Sci Med Sci 68:465-72. 2013..The longer healthy life expectancy observed in Japan may be partly attributed to the Japanese diet. The researchers sought to examine whether serum isoflavone levels are associated with disability and death...
Relationship between serum adiponectin levels and disability-free survival among community-dwelling elderly individuals: The Tsurugaya ProjectAtsushi Hozawa
Department of Public Health, Yamagata University Graduate School of Medical Science, Yamagata, Japan
J Gerontol A Biol Sci Med Sci 67:530-6. 2012..The objective of this study was to clarify whether the relationship between adiponectin and a higher risk of disability or death can be explained by physical function, bone mineral density, depression, and malnutrition...
Dietary patterns associated with fall-related fracture in elderly Japanese: a population based prospective studyYasutake Monma
Center for Asian Traditional Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
BMC Geriatr 10:31. 2010..Therefore we investigated the relationship between dietary patterns and fall-related fractures in the elderly...
Green tea consumption is associated with lower psychological distress in a general population: the Ohsaki Cohort 2006 StudyAtsushi Hozawa
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Am J Clin Nutr 90:1390-6. 2009..Although green tea or its constituents might reduce psychological stress, the relation between green tea consumption and psychological distress has not been investigated in a large-scale study...
Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80Atsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
Obesity (Silver Spring) 16:1714-7. 2008..0-22.9 and 23.0-24.9 kg/m(2). Our findings do not support the recent WHO implications that BMIs <23.0 kg/m(2) is healthy for Asians. Therefore, further studies are needed to identify an optimal BMI range for Asia...
Participation in health check-ups and mortality using propensity score matched cohort analysesAtsushi Hozawa
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Prev Med 51:397-402. 2010..Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions...
Benefit of home blood pressure measurement after a finding of high blood pressure at a community screeningAtsushi Hozawa
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
J Hypertens 24:1265-71. 2006....
Attributable risk fraction of prehypertension on cardiovascular disease mortality in the Japanese population: the Ohsaki StudyAtsushi Hozawa
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Am J Hypertens 22:267-72. 2009..However, no studies have reported the fraction...
Seasonal variation in home blood pressure measurements and relation to outside temperature in JapanAtsushi Hozawa
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Clin Exp Hypertens 33:153-8. 2011..06 and 0.01 mmHg when the outside temperature was <10°C. In conclusion, inverse association between outside temperature and BP was observed only in warmer seasons...
Introversion associated with large differences between screening blood pressure and home blood pressure measurement: The Ohasama studyAtsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Shiga, Japan
J Hypertens 24:2183-9. 2006..To explore the effect of personality on screening blood pressures measured in clinical settings and home blood pressure measurements...
High blood pressure in middle age is associated with a future decline in activities of daily living. NIPPON DATA80A Hozawa
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aobaku, Sendai 980 8575, Japan
J Hum Hypertens 23:546-52. 2009..7/75) of impaired ADL. A positive relation of BP categories with the composite end point of mortality and impaired ADL was also observed. In conclusion, controlling BP in middle age may prevent deaths and future ADL decline...
Factors affecting home-measured resting heart rate in the general population: the Ohasama studyJunko Yamaguchi
Departments of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science and Medicine, 1-1 Seiryomachi, Aobaku, Sendai 980-8574, Japan
Am J Hypertens 18:1218-25. 2005..These results suggest that reduction of home HR through modification of smoking habit or sedentary lifestyle may have a potential to decrease cardiovascular risk in addition to decreasing in these modifiable risk factor per se...
Relationships between family histories of stroke and of hypertension and stroke mortality: NIPPON DATA80, 1980-1999Aya Kadota
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
Hypertens Res 31:1525-31. 2008..00-2.24) even after adjustment for systolic blood pressure. In conclusion, a family history of stroke could not predict total stroke mortality. However, a family history of hypertension might predict an increased risk for total stroke...
Low-risk profile for cardiovascular disease and mortality in JapaneseTakako Yamamoto
Department of Health Science, Shiga University of Medical Science, Seta Tukinowa cho, Otsu 520 2192, Japan
Circ J 72:545-50. 2008..This study examines whether having a favorable risk factor profile yields lower all-cause mortality and whether the proportion of those with a low-risk profile is larger in the Japanese population...
Obesity and risk of cancer in JapanShinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan
Int J Cancer 113:148-57. 2005..2% (all subjects) or 3.7% (never-smokers) in men. The value for women was within the range among women reported from Western populations (3.2%-8.8%). Our data demonstrate that excess weight is a major cancer risk among Japanese women...
History of cholelithiasis and the risk of prostate cancer: the Ohsaki Cohort StudyQiang Li
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Int J Cancer 128:185-91. 2011..The associations were robust after adjustment for different potential confounders. This population-based prospective cohort study indicates that a history of cholelithiasis is associated with an increased incidence of prostate cancer...
Dietary intakes and plasma 8-iso-prostaglandin F2alpha concentrations in community-dwelling elderly Japanese: the Tsurugaya projectShinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
Int J Vitam Nutr Res 76:87-94. 2006..These associations were partly explained by vitamin C intake. Other dietary intakes had no association. Intake of fruits may have a beneficial effect against oxidative stress in elderly Japanese...
Home blood pressure is associated with depressive symptoms in an elderly population aged 70 years and over: a population-based, cross-sectional analysisKaijun Niu
Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
Hypertens Res 31:409-16. 2008..Further study is required to clarify the causality of this relationship...
T+31C polymorphism (M235T) of the angiotensinogen gene and home blood pressure in the Japanese general population: the Ohasama StudyMitsunobu Matsubara
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan
Hypertens Res 26:47-52. 2003....
Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project 1Shinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Am J Clin Nutr 83:355-61. 2006....
Joint impact of smoking and hypertension on cardiovascular disease and all-cause mortality in Japan: NIPPON DATA80, a 19-year follow-upAtsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
Hypertens Res 30:1169-75. 2007..Efforts to warn about the adverse consequence of HT and smoking during adolescence and youth could yield the greatest health benefits, since positive behaviors adopted early are more easily continued into middle adulthood and later life...
Health practices and mortality in Japan: combined effects of smoking, drinking, walking and body mass index in the Miyagi Cohort StudyYoshitaka Tsubono
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan
J Epidemiol 14:S39-45. 2004..CONCLUSONS: In this prospective cohort study of middle-aged men and women in rural Japan, a larger number of high-risk practices was associated with linear increase in risk of all-cause mortality...
Predictive value of ambulatory heart rate in the Japanese general population: the Ohasama studyAtsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
J Hypertens 26:1571-6. 2008..However, only a few studies have described the relationship between heart rate measured by ambulatory blood pressure monitoring devices and cardiovascular disease prediction...
The Ohsaki Cohort 2006 Study: design of study and profile of participants at baselineShinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
J Epidemiol 20:253-8. 2010..Large-scale cohort studies conducted in Japan do not always include psychosocial factors as exposures. In addition, such studies sometimes fail to satisfactorily evaluate disability status as an outcome...
Factors associated with psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 StudyShinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
J Epidemiol 19:294-302. 2009..In Asia, there has been no population-based epidemiological study using the K6, a 6-item instrument that assesses nonspecific psychological distress...
Relationship of moderate metabolic risk factor clustering to cardiovascular disease mortality in non-lean Japanese: a 15-year follow-up of NIPPON DATA90Aya Kadota
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
Atherosclerosis 215:209-13. 2011..We investigated the impact of moderate metabolic risk factor clustering on cardiovascular disease (CVD) mortality...
Cigarette smoking in middle age and a long-term risk of impaired activities of daily living: NIPPON DATA80Naoyuki Takashima
Department of Health Science, Shiga University of Medical Science, Seta tsukinowa cho, Otsu, Shiga 520 2192, Japan
Nicotine Tob Res 12:944-9. 2010..Few studies have reported the relationship between smoking in middle age and long-term risk of impaired activities of daily living (ADL)...
Relation of adult height with stroke mortality in Japan: NIPPON DATA80Atsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Setatsukinowa cho, Otsu, 520 2192, Shiga, Japan
Stroke 38:22-6. 2007..In addition to improved management of high blood pressure, the increase in average height might also contribute to this reduction. The present study investigates whether height is an independent risk for stroke mortality in Japan...
Cancer incidence profiles in the Miyagi Cohort StudyYoshikazu Nishino
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan
J Epidemiol 14:S7-11. 2004..We expect this data to contribute to the progress of research on cancer etiology and cancer prevention...
History of diabetes mellitus and the risk of prostate cancer: the Ohsaki Cohort StudyQiang Li
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980 8575, Japan
Cancer Causes Control 21:1025-32. 2010..However, no evidence from cohort studies is available for Asian populations, whose lifestyle is very different from that of westerners...
Association between social support and depression status in the elderly: results of a 1-year community-based prospective cohort study in JapanYayoi Koizumi
Department of Psychiatry, Tohoku University Graduate School of Medicine, Miyagi, Japan
Psychiatry Clin Neurosci 59:563-9. 2005..We conclude that there is a significant increase in the risk of depression status associated with the lack of social support in Japanese elderly people in an urban community...
Green tea consumption and the risk of incident functional disability in elderly Japanese: the Ohsaki Cohort 2006 StudyYasutake Tomata
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
Am J Clin Nutr 95:732-9. 2012..Although it is expected that green tea consumption would lower the risk of incident functional disability, this has never been investigated directly...
Prognostic value of home heart rate for cardiovascular mortality in the general population: the Ohasama studyAtsushi Hozawa
Department of Public Health, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
Am J Hypertens 17:1005-10. 2004..We therefore investigated the usefulness of HR values in predicting cardiovascular mortality using a device that allowed self-measurement of BP and HR at home...
The proportion of individuals with alcohol-induced hypertension among total hypertensives in a general Japanese population: NIPPON DATA90Koshi Nakamura
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
Hypertens Res 30:663-8. 2007..8% for 1 gou/day, 0.7% for 2 gou/day or more, and -0.1% for ex-drinkers in women. In conclusion, we found that a large percentage of the hypertensives in a general Japanese male population had alcohol-induced hypertension...
Integration of data from NIPPON DATA80/90 and National Nutrition Survey in Japan: for cohort studies of representative Japanese on nutritionNagako Okuda
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
J Epidemiol 20:S506-14. 2010..NIPPON DATA80/90 is cohort study of representative Japanese population, and the cohorts also participated in the National Nutrition Survey in Japan (NNSJ) at the baseline. The corresponding datasets could be combined...
Dietary patterns and cardiovascular disease mortality in Japan: a prospective cohort studyTaichi Shimazu
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, Miyagi 980 8575, Japan
Int J Epidemiol 36:600-9. 2007..Although ecological observations suggest that the Japanese diet may reduce the risk of cardiovascular disease (CVD), the impact of a Japanese dietary pattern upon mortality due to CVD is unclear...
White-coat hypertension as a risk factor for the development of home hypertension: the Ohasama studyTakashi Ugajin
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Medicine and Pharmaceutical Sciences, Sendai, Japan
Arch Intern Med 165:1541-6. 2005....
Coffee consumption and mortality due to all causes, cardiovascular disease, and cancer in Japanese womenKemmyo Sugiyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai 980 8575, Japan
J Nutr 140:1007-13. 2010..Our results suggest that coffee may have favorable effects on morality due to all causes and to CVD, especially CHD, in women...
Progress report on the HOMED-BP Study: hypertension objective treatment based on measurement by electrical devices of blood pressure studyYohei Aoki
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan
Clin Exp Hypertens 26:119-27. 2004..At the end of March 2002, 546 patients were recruited. Of these, 412 (202 men and 210 women, aged 58.4 +/- 10.2 y) were randomized. Patients will be recruited until February, 2006 and followed for 7 years...
Is weak association between cigarette smoking and cardiovascular disease mortality observed in Japan explained by low total cholesterol? NIPPON DATA80Atsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Shiga, Japan
Int J Epidemiol 36:1060-7. 2007..However, little has been published about the relationship between smoking and CVD mortality among populations with various cholesterol levels...
Effect of combined cardiovascular risk factors on individual and population medical expenditures: a 10-year cohort study of national health insurance in a Japanese populationTomonori Okamura
Department of Health Science, Shiga University of Medical Science, Seta tsukinowa cho, Otsu 520 2192, Japan
Circ J 71:807-13. 2007..Whether the relationship between cardiovascular risk factor clustering and medical expenditures differs with body mass index (BMI) requires investigation, especially in a population with a low prevalence of obesity such as that in Japan...
Modifiable factors for the length of life with disability before death: mortality retrospective study in JapanKaori Ohmori
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Gerontology 51:186-91. 2005..Past studies have measured and described the length of life with disability before death, but there has been no study of the relationship between modifiable lifestyle factors and duration of disability...
Lower levels of serum albumin and total cholesterol associated with decline in activities of daily living and excess mortality in a 12-year cohort study of elderly JapaneseTomonori Okamura
Department of Health Science, Shiga University of Medical Science, Otsu, Shiga, Japan
J Am Geriatr Soc 56:529-35. 2008..To examine the association between levels of serum albumin and total cholesterol (TC) and risk of subsequent mortality and future decline in activities of daily living (ADLs) in elderly people...
Relationships of circulating carotenoid concentrations with several markers of inflammation, oxidative stress, and endothelial dysfunction: the Coronary Artery Risk Development in Young Adults (CARDIA)/Young Adult Longitudinal Trends in Antioxidants (YALTAtsushi Hozawa
Division of Epidemiology and Community Health, School of Public Health, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, University of Minnesota, Minneapolis, MN 55454, USA
Clin Chem 53:447-55. 2007..To clarify the effect of carotenoids on atherosclerotic risk factors, we examined the association of circulating carotenoids with inflammation, oxidative stress, endothelial dysfunction, and smoking...
The proportion of individuals with obesity-induced hypertension among total hypertensives in a general Japanese population: NIPPON DATA80, 90Koshi Nakamura
Department of Health Science, Shiga University of Medical Science, Seta tsukinowa cho, Otsu City, Shiga, 520 2192, Japan
Eur J Epidemiol 22:691-8. 2007..Obesity now is playing a more important role in the high prevalence of hypertension in Japan than it was before...
Green tea and death from pneumonia in Japan: the Ohsaki cohort studyIkue Watanabe
Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Am J Clin Nutr 90:672-9. 2009..No data are available on the association between green tea consumption and the risk of pneumonia in humans...
Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine productsKaijun Niu
Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
Am J Clin Nutr 84:223-9. 2006..Therefore, it is still unclear whether a greater consumption of n-3 PUFAs is associated with lower serum CRP concentrations...
Cigarette smoking and mortality in Japan: the Miyagi Cohort StudyAtsushi Hozawa
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan
J Epidemiol 14:S12-7. 2004..CONCLUSIONS: This study indicates that smoking increases the risk of premature death among middle-aged Japanese men and women and that substantial proportion of death, especially for men, is attributable to smoking...
Effect of age on the association between body mass index and all-cause mortality: the Ohsaki cohort studyMasato Nagai
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Miyagi, Japan
J Epidemiol 20:398-407. 2010..To clarify the effect of age on the association between body mass index (BMI) and all-cause mortality...
Passive smoke exposure and circulating carotenoids in the CARDIA studyRachel Widome
Center for Chronic Disease Outcomes Research, Minneapolis Veterans Affairs Medical Center, Minneapolis, MN, USA
Ann Nutr Metab 56:113-8. 2010..Conclusion: Cross-sectionally, in 1985/86, passive smoke exposure in various venues was associated with reduced levels of provitamin A serum carotenoids...
Green tea consumption and hematologic malignancies in Japan: the Ohsaki studyToru Naganuma
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University School of Medicine, Miyagi, Japan
Am J Epidemiol 170:730-8. 2009..32, 1.78) for myeloid neoplasms. This inverse association was consistent across sex and body mass index strata. In conclusion, green tea consumption was associated with a lower risk of hematologic malignancies...
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurementsJunichiro Hashimoto
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
J Hypertens 21:805-11. 2003..To clarify the effects of bedtime administration of the centrally acting alpha(2)-agonists, guanabenz and clonidine, on morning hypertension...
C-reactive protein (CRP) is a predictor of high medical-care expenditures in a community-based elderly population aged 70 years and over: the Tsurugaya projectKaijun Niu
Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan
Arch Gerontol Geriatr 54:e392-7. 2012..Further study is required to clarify whether reducing CRP by intervention is a cost-effective measure...
Green tea consumption and the risk of liver cancer in Japan: the Ohsaki Cohort studyAkane Ui
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, Miyagi 980 8575, Japan
Cancer Causes Control 20:1939-45. 2009..To investigate the association between green tea consumption and liver cancer incidence...
Serum C-reactive protein even at very low (<1.0 mg/l) concentration is associated with physical performance in a community-based elderly population aged 70 years and overKaijun Niu
Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
Gerontology 54:260-7. 2008..Therefore, it is still unclear whether a lower CRP is favorably associated with physical performance even within a very low range...
Relation of Gamma-glutamyltransferase and alcohol drinking with incident diabetes: the HIPOP-OHP studyAtsushi Hozawa
Department of Health Science, Shiga University of Medical Science, Otsu, Japan
J Atheroscler Thromb 17:195-202. 2010..In this study, we investigated the relation of GGT or alcohol drinking with DM incidence considering the body mass index (BMI) in healthy Japanese workers...
Relationship between peripheral arterial disease and incident disability among elderly Japanese: the Tsurugaya projectAkemi Nitta
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
J Atheroscler Thromb 17:1290-6. 2010..The aim of this study was to investigate whether peripheral arterial disease (PAD) is predictive of disability and whether the relationship between PAD and disability can be fully explained by baseline physical functions...
Incorporating self-blood pressure measurements at home in the guideline from the Ohasama studyTakayoshi Ohkubo
Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences and Medicine, Sendai, Japan
Blood Press Monit 12:407-9. 2007..We expect that continuous follow-up and further analysis of the Ohasama data would contribute to producing further important findings worth incorporating in future hypertension guidelines...
Relationship between metabolic risk factor clustering and cardiovascular mortality stratified by high blood glucose and obesity: NIPPON DATA90, 1990-2000Aya Kadota
Department of Health Science, Shiga University of Medical Science, Seta tsukinowa cho, Otsu 520 2192, Japan
Diabetes Care 30:1533-8. 2007..We investigated the relationship between metabolic risk factor clustering and cardiovascular disease (CVD) mortality stratified by high blood glucose or obesity...
A/C1166 gene polymorphism of the angiotensin II type 1 receptor (AT1) and ambulatory blood pressure: the Ohasama StudyMasahiro Kikuya
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
Hypertens Res 26:141-5. 2003..These results indicated that AT1 A/C1166 polymorphism was not associated with any clinical parameters associated with hypertension or atherosclerosis in the Japanese population...
Follow-up and mortality profiles in the Miyagi Cohort StudyIchiro Tsuji
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan
J Epidemiol 14:S2-6. 2004..CONCLUSIONS: In this cohort study, both the participation rate and the follow-up rate are satisfactorily high. We expect this Miyagi Cohort Study to provide the society with evidence for health promotion and disease prevention...
T+31C polymorphism of angiotensinogen gene and nocturnal blood pressure decline: the Ohasama studyTohru Fujiwara
Department of Clinical Pharmacology, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan
Am J Hypertens 15:628-32. 2002..We assessed the association between several polymorphisms of angiotensinogen gene (AGT) and essential hypertension using ambulatory blood pressure (BP)...
Gamma-glutamyltransferase and cancer incidence: the Ohsaki cohort studyToru Tsuboya
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
J Epidemiol 22:144-50. 2012..The present study investigated the association between GGT and cancer incidence and assessed the role of alcohol consumption in this association...
The relationship between body mass index and a plasma lipid peroxidation biomarker in an older, healthy Asian communityKaori Ohmori
Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Ann Epidemiol 15:80-4. 2005..This cross-sectional study included 1150 community-dwelling Japanese aged 70 years or older in 2002...
Prognostic value of q wave for cardiovascular death in a 19-year prospective study of the Japanese general populationAya Higashiyama
Department of Health Science, Shiga University of Medical Science, Ostu, Japan
J Atheroscler Thromb 16:40-50. 2009..Little is known about the prognostic value of q wave abnormality for cardiovascular disease (CVD) on a resting electrocardiogram (ECG) of the Japanese general population with an extremely low incidence of myocardial infarction...
Joint impact of health risks on health care charges: 7-year follow-up of National Health Insurance beneficiaries in Japan (the Ohsaki Study)Shinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Prev Med 39:1194-9. 2004..The objective of this study was to examine the joint impact of modifiable health-risk factors such as smoking, obesity, and physical inactivity on direct health care charges...
Association between green tea consumption and tooth loss: cross-sectional results from the Ohsaki Cohort 2006 StudyYasushi Koyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Prev Med 50:173-9. 2010..To examine the association between green tea consumption and tooth loss...
Insufficient duration of action of antihypertensive drugs mediates high blood pressure in the morning in hypertensive population: the Ohasama studyKenichi Chonan
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science and Medicine, Sendai, Japan
Clin Exp Hypertens 24:261-75. 2002..The high morning BP accompanies so-called non-dipper pattern of circadian BP variation. An insufficient duration of action of drugs may partly mediate non-dipping in subjects with antihypertensive medication...
Pulse wave velocity and the second derivative of the finger photoplethysmogram in treated hypertensive patients: their relationship and associating factorsJunichiro Hashimoto
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
J Hypertens 20:2415-22. 2002..To clarify the factors influencing two measures of arterial stiffness, pulse wave velocity (PWV) and the second derivative of the finger photoplethysmogram (SDPTG), and to evaluate their relationship in treated hypertensive subjects...
Angiotensin-converting enzyme I/D polymorphism and hypertension: the Ohasama studyMitsunobu Matsubara
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
J Hypertens 20:1121-6. 2002....
Blood pressure control assessed by home, ambulatory and conventional blood pressure measurements in the Japanese general population: the Ohasama studyAtsushi Hozawa
Department of Public Health, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
Hypertens Res 25:57-63. 2002....
Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects--Atherosclerosis Risk in Communities StudyAtsushi Hozawa
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
Arch Intern Med 167:573-9. 2007..Among white Americans, a large proportion of cardiovascular disease (CVD) events is explained by borderline or any elevated CVD risk factor levels. The degree to which this is true among African American subjects is unclear...
The joint impact of cardiovascular risk factors upon medical costsKaori Ohmori-Matsuda
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo machi, Aoba ku, Sendai, 980 8575, Japan
Prev Med 44:349-55. 2007..The joint impact of obesity, hypertension, and hyperglycemia upon medical costs is not well known. Our objective was to evaluate the joint impact of these cardiovascular risk factors upon medical costs in the rural Japanese population...
Determinants of the utilization of dental services in a community-dwelling elderly Japanese populationTakashi Ohi
Division of Aging and Geriatric Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan
Tohoku J Exp Med 218:241-9. 2009....
Factors associated with suicidal ideation in an elderly urban Japanese population: a community-based, cross-sectional studyShuichi Awata
Department of Psychiatry, Tohoku University Graduate School of Medicine, Sendai, Japan
Psychiatry Clin Neurosci 59:327-36. 2005....
Relation of blood pressure and all-cause mortality in 180,000 Japanese participants: pooled analysis of 13 cohort studiesYoshitaka Murakami
Department of Health Science, Shiga University of Medical Science, Seta tsukinowa cho, Otsu City, Shiga, 520 2192, Japan
Hypertension 51:1483-91. 2008..In conclusion, high blood pressure raised the risk of total mortality, and this trend was higher in the younger Japanese population...
Personality and the risk of cancerNaoki Nakaya
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
J Natl Cancer Inst 95:799-805. 2003..The association between neuroticism and prevalent cancer may be a consequence, rather than a cause, of cancer diagnosis or symptoms...
Effects of exercise training on physical activity in older people: a randomized controlled trialKazuki Fujita
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
J Epidemiol 13:120-6. 2003..7 kcal/kg/day, than that at the pre-intervention (p = 0.05). CONCLUSIONS: This randomized controlled trial indicated that exercise training for elderly was effective in increasing physical activity in daily life...
Increased plasma 8-isoprostane levels in hypertensive subjects: the Tsurugaya ProjectAtsushi Hozawa
Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine and Pharmaceutical Science, Sendai, Japan
Hypertens Res 27:557-61. 2004..Thus, the level of plasma 8-isoprostane appears to be elevated in older subjects with severe hypertension...
Association between physical activity and urinary incontinence in a community-based elderly population aged 70 years and overAkio Kikuchi
Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
Eur Urol 52:868-74. 2007..The objective of the present study was to evaluate the association between physical activity (PA) levels and urinary incontinence (UI) in a community-based elderly population aged > or =70 yr...
Serum uric acid and risk of ischemic stroke: the ARIC StudyAtsushi Hozawa
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454-1015, USA
Atherosclerosis 187:401-7. 2006..08). CONCLUSION: Our findings suggest that UA is an independent predictor of ischemic stroke among subjects not using diuretics, but that elevated UA itself may not cause ischemic stroke...
The association of cigarette smoking with self-reported disease before middle age: the Coronary Artery Risk Development in Young Adults (CARDIA) studyAtsushi Hozawa
Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA
Prev Med 42:193-9. 2006..Thus, prevention, cessation, and avoiding passive smoking should remain strong goals among young people...
No effect of the Trp64Arg variant of the beta3-adrenergic receptor gene on weight loss by diet and exercise intervention among Japanese adultsShinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980 8575, Japan
Metabolism 57:1570-5. 2008..47 (95% CI, -1.97 to 1.02). These results suggest that the presence of the Trp64Arg variant of the beta(3)-adrenergic receptor gene may not play a major role as a hindrance to weight reduction...
Obesity and depressive symptoms in elderly Japanese: the Tsurugaya ProjectShinichi Kuriyama
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
J Psychosom Res 60:229-35. 2006..The aim of this study is to examine the association between obesity and depressive symptoms in Japan...
[Ambulatory blood pressure monitoring and self-measurement of blood pressure at home]Atsushi Hozawa
Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine
Nippon Rinsho 62:403-7. 2004
Lung function and ischemic stroke incidence: the Atherosclerosis Risk in Communities studyAtsushi Hozawa
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454-1015, USA
Chest 130:1642-9. 2006..CONCLUSIONS: Among white subjects, participants with impaired lung function have a modestly higher risk of ischemic stroke even if they have never smoked nor had respiratory symptoms...
Citrus consumption and cancer incidence: the Ohsaki cohort studyWen Qing Li
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Aoba ku, Sendai, Japan
Int J Cancer 127:1913-22. 2010..Further work on the specific citrus constituents is warranted, and clinical trials are ultimately necessary to confirm the protective effect...
Personality and mortality from ischemic heart disease and strokeNaoki Nakaya
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Clin Exp Hypertens 27:297-305. 2005..The role of personality in the causation of circulatory diseases has been controversial...
[Malnutrition and the risk of long-term care insurance certification or mortality. A cohort study of the Tsurugaya project]Mizuka Higashiguchi
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
Nihon Koshu Eisei Zasshi 55:433-9. 2008..The purpose of this study was to propose a suitable cut-off point for the serum albumin value to predict which elderly individuals are qualified for long-term care insurance certification and those at risk of death...
Associations of serum carotenoid concentrations with the development of diabetes and with insulin concentration: interaction with smoking: the Coronary Artery Risk Development in Young Adults (CARDIA) StudyAtsushi Hozawa
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, 55454, USA
Am J Epidemiol 163:929-37. 2006..46 (p = 0.03); per SD increase in insulin resistance, slope = -0.14 (p = 0.01)). In CARDIA, higher serum carotenoid concentrations are associated with lower risk of diabetes and insulin resistance in nonsmokers but not in smokers...
Life expectancy among Japanese of different smoking status in Japan: NIPPON DATA80Yoshitaka Murakami
Department of Health Science, Shiga University of Medical Science, Japan
J Epidemiol 17:31-7. 2007..No such study is examined in Japan, the country with the world's highest life expectancy irrespective of high smoking rate among men...
alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama studyKen Sugimoto
Department of Geriatric Medicine, Osaka University Graduate School of Medicine, Suita, Japan
J Hypertens 20:1779-84. 2002..However, we failed to detect a positive association between the Gly460Trp polymorphism of ADD-1 and hypertension in a small series of Japanese subjects...
gamma-Glutamyltransferase predicts cardiovascular death among Japanese womenAtsushi Hozawa
Department of Health Science, Shiga University of Medical Science, SetaTsukinowa cho Otsu, 520 2192 Shiga, Japan
Atherosclerosis 194:498-504. 2007..Exploring the significance and biological mechanisms of GGT might provide useful insights into CVD prevention...
Heart rate measurement and outcomeYutaka Imai
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science and Medicine, 1 1 Seiryomachi Aobaku, Japan, 980 8574
Blood Press Monit 8:53-5. 2003..In conclusion, heart rate and heart rate variability must not be overlooked when evaluating hypertension...
Does the impact of smoking on coronary heart disease differ by low-density lipoprotein cholesterol level?: the Atherosclerosis Risk in Communities (ARIC) StudyAtsushi Hozawa
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, MN, USA
Circ J 70:1105-10. 2006....
Influence of leisure-time physical activity on the relationship between C-reactive protein and hypertension in a community-based elderly population of Japan: the Tsurugaya projectKaijun Niu
Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan
Hypertens Res 28:747-54. 2005..This is the first study to clarify that the positive significant relation between CRP and hypertension was independent of LTPA levels among Japanese elderly...
[Association between social support and depression in the elderly Japanese population]Yayoi Koizumi
Department of Psychiatry, Tohoku University Graduate School of Medicine
Nihon Ronen Igakkai Zasshi 41:426-33. 2004..2 (0.8-1.8),(3) 1.4 (1.0-2.0),(4) 1.6 (1.1-2.3),(5) 2.0 (1.4-2.9) in women. A significant association was found between social support and depression in this elderly population. We also found that this association was stronger in men...
Relationship between personality and self-measured blood pressure value at home: the Ohasama studyAtsushi Hozawa
Department of Public Health, Tohoku University Graduate School of Medicine, Sendai, Japan
Clin Exp Hypertens 24:115-23. 2002..When physicians investigate the pathogenesis of essential hypertension, they should take psychological factors into consideration, as well as the many environmental and genetic factors...
Fruit and vegetable consumption and risk of colorectal cancer in Japan: The Miyagi Cohort StudyYuki Sato
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, 2 1 Seiryo, Aoba, Sendai 980 8575, Japan
Public Health Nutr 8:309-14. 2005..However, several recent prospective studies have reported no association. We therefore examined the association between fruit and vegetable intakes and the risk of colorectal cancer in a prospective cohort study in Japan...
