Research Topics
Species | Y HommaSummaryAffiliation: University of Tokyo Country: Japan Publications
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Detail Information
Publications
Radical prostatectomy and adjuvant endocrine therapy for prostate cancer with or without preoperative androgen deprivation: Five-year resultsYukio Homma
Department of Urology, University of Tokyo, Tokyo, Japan
Int J Urol 11:295-303. 2004..The effects of preoperative androgen deprivation on the outcomes of prostate cancer patients who received radical prostatectomy and subsequent adjuvant endocrine therapy have not yet been fully evaluated...- Minimal clinically important change in urinary incontinence detected by a quality of life assessment tool in overactive bladder syndrome with urge incontinenceYukio Homma
Department of Urology, Japanese Red Cross Medical Center, Tokyo, Japan
Neurourol Urodyn 25:228-35. 2006..CONCLUSION: Japanese OAB patients can feel their QOL improved if their incontinence episodes decrease more than 3 times/w. This suggests that the reduction of '3 times /w' is an MCIC of incontinence frequency for Japanese OAB patients... 
Transcriptional control region rearrangements associated with the evolution of JC polyomavirusYoshiaki Yogo
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Virology 380:118-23. 2008..This observation suggests that during the course of JCV evolution, JCV strains with sporadic rearrangements became predominant over archetypal TCRs in some JCV lineages or sub-lineages...- Psychometric validation of the Japanese version of the International Consultation on Incontinence Questionnaire-Short FormMomokazu Gotoh
Department of Urology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
Int J Urol 16:303-6. 2009..To evaluate the psychometric properties of the Japanese version of the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)... - Assessment of overactive bladder symptoms: comparison of 3-day bladder diary and the overactive bladder symptoms scoreYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Urology 77:60-4. 2011..To compare the Overactive Bladder Symptom Score (OABSS) and a bladder diary as a tool for assessing symptoms of overactive bladder (OAB)... 
Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese menMiao Liu
Department of Urology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
BMC Genet 10:37. 2009..Here, we evaluated whether the single-nucleotide polymorphisms rs1447295 and rs6983267 were associated with the risk of sporadic prostate cancer as well as latent prostate cancer in a native Japanese population...- Clinical efficacy and tolerability of extended-release tolterodine and immediate-release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo-controlled trialY Homma
Department of Urology, Tokyo University, Tokyo, Japan
BJU Int 92:741-7. 2003..To compare extended-release (ER) tolterodine and immediate-release (IR) oxybutynin with placebo in Japanese and Korean patients with an overactive bladder (OAB)... - Symptom severity and patient perceptions in overactive bladder: how are they related?Yukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Japan
BJU Int 104:968-72. 2009..To assess the relationship between symptom severity and patient perceptions in patients with overactive bladder (OAB), as estimated by OAB Symptom Score (OABSS) and patient-reported outcome measures, respectively... - Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostateYukio Homma
Department of Urology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
Carcinogenesis 25:1011-4. 2004..The role of dietary fat and oxidative stress in prostate carcinogenesis needs further investigation... - Japanese guideline for diagnosis and treatment of interstitial cystitisYukio Homma
Department of Urology, Tokyo University Graduate School of Medicine, Tokyo
Int J Urol 16:4-16. 2009..This article is the English translation of a shortened version of the Guideline for convenience of readers worldwide... - Endocrine therapy with or without radical prostatectomy for T1b-T3N0M0 prostate cancerYukio Homma
Department of Urology, University of Tokyo, Tokyo, Japan
Int J Urol 11:218-24. 2004..We retrospectively compared the 5-year survival rates of T1b-T3N0M0 prostate cancer patients treated either by endocrine therapy plus radical prostatectomy or endocrine therapy alone... - Should an antimuscarinic agent be used for persistent LUTS after treatment with an alpha(1)-blocker?Yukio Homma
Department of Urology, Tokyo University Graduate School of Medicine, Tokyo, Japan
Nat Clin Pract Urol 6:66-7. 2009..Better evaluation of storage symptoms might facilitate the more-appropriate use of combined treatment in this setting... - Health-related quality of life of Japanese patients with overactive bladder treated with extended-release tolterodine or immediate-release oxybutynin: a randomized, placebo-controlled trialY Homma
Department of Urology, Tokyo University Hospital, 7 3 1 Hongo Bunkyo ku, 113 8655 Tokyo, Japan
World J Urol 22:251-6. 2004..Our findings demonstrate that Japanese OAB patients receiving tolterodine ER or oxybutynin experienced overall improvement in their quality of life... - Long-term safety, tolerability, and efficacy of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladderYukio Homma
Department of Urology, University of Tokyo, Tokyo, Japan
Int J Urol 15:986-91. 2008..To evaluate the long-term safety, tolerability, and efficacy of imidafenacin, a novel anti-muscarinic agent, in Japanese patients with overactive bladder... - Classification of nocturia in the adult and elderly patient: a review of clinical criteria and selected literatureYukio Homma
Division of Urology, Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
BJU Int 96:8-14. 2005..The application of valid diagnostic criteria to differentiate the underlying cause of nocturia should help lead to more appropriate and effective management of this pervasive problem... - An epidemiological survey of overactive bladder symptoms in JapanYukio Homma
Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
BJU Int 96:1314-8. 2005.... - Core Lower Urinary Tract Symptom score (CLSS) questionnaire: a reliable tool in the overall assessment of lower urinary tract symptomsYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 15:816-20. 2008..To identify the symptoms of higher relevance in patients complaining of lower urinary tract symptoms (LUTS)... - Lower urinary tract symptomatology: Its definition and confusionYukio Homma
Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
Int J Urol 15:35-43. 2008..This review has detailed definitions and confusions related to the latest version, and suggested possible solutions for a better vocabulary of words... - Symptom assessment tool for overactive bladder syndrome--overactive bladder symptom scoreYukio Homma
Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
Urology 68:318-23. 2006..Overactive bladder (OAB) is a common symptom syndrome with urgency, urinary frequency, and urgency incontinence. To collectively express OAB symptoms, we developed the overactive bladder symptom score (OABSS)... - A randomized, double-blind, placebo- and propiverine-controlled trial of the novel antimuscarinic agent imidafenacin in Japanese patients with overactive bladderYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 16:499-506. 2009..To compare the efficacy and tolerability of imidafenacin, a novel antimuscarinic agent, with propiverine and a placebo in Japanese patients with overactive bladder (OAB)... - Epidemiologic survey of lower urinary tract symptoms in JapanYukio Homma
Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
Urology 68:560-4. 2006..A large-scale nationwide epidemiologic survey was performed to determine the prevalence of lower urinary tract symptoms (LUTS) and their impact on health-related quality of life (HRQOL) in Japan... - Ejaculation disorder is associated with increased efficacy of silodosin for benign prostatic hyperplasiaYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Urology 76:1446-50. 2010..To provide clinical evidence that ejaculation disorder caused by selective alpha(1A)-blockers may be associated with larger symptomatic improvements in patients with benign prostatic hyperplasia... - Clinical guideline for male lower urinary tract symptomsYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 16:775-90. 2009..Treatment with anticholinergic agents should be reserved only for urologists, considering the risk of urinary retention. The present guideline should help urologists and especially non-urologists treat men with LUTS... - Outline of JUA clinical guidelines for benign prostatic hyperplasiaYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 18:741-56. 2011..Surgical intervention is indicated when non-surgical treatments fail to provide sufficient symptomatic relief and bladder outlet obstruction is highly suspected... - Voiding and incontinence frequencies: variability of diary data and required diary lengthYukio Homma
Department of Urology, Tokyo University, Tokyo, Japan
Neurourol Urodyn 21:204-9. 2002..However, the diary length should be extended in a patient with rarer events of incontinence, and it should be shortened for those who are incontinent more often or who are diagnosed with voiding frequency only... - Clinical guidelines for interstitial cystitis and hypersensitive bladder syndromeYukio Homma
Department of Urology, Graduate School of Medicine, The University of Tokyo, Bunkyoku, Tokyo, Japan
Int J Urol 16:597-615. 2009..The inclusion and efficacy criteria for clinical trials should be standardized to enhance the clinical research for this disabling disease, which has proved to be more prevalent than previously believed... - Early results of radical prostatectomy and adjuvant endocrine therapy for prostate cancer with or without preoperative androgen deprivation. The Prostate Cancer Study GroupY Homma
Department of Urology, University of Tokyo, Japan
Int J Urol 6:229-37; discussion 238-9. 1999..The effects of preoperative androgen deprivation were explored in the patients who received radical prostatectomy and subsequent adjuvant endocrine therapy for prostate cancer... - Early results of LH-RH agonist treatment with or without chlormadinone acetate for hormone therapy of naive localized or locally advanced prostate cancer: a prospective and randomized study. The Prostate Cancer Study GroupH Akaza
Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
Jpn J Clin Oncol 30:131-6. 2000..In this situation, primary hormone therapy is an alternative treatment option. We have designed a prospective randomized study of the effects of primary hormone therapy for such patients... - Lower incidence of inguinal hernia after radical prostatectomy using open gasless endoscopic single-site surgeryH Fukuhara
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Prostate Cancer Prostatic Dis 14:162-5. 2011..The hernia-free survival was significantly higher after MIES-RRP than after conventional RRP (P=0.037). Our results suggest that MIES-RRP is less associated with post-operative inguinal hernia than conventional RRP... - Use of the short form of King's Health Questionnaire to measure quality of life in patients with an overactive bladderY Homma
Graduate School of Medicine, University of Tokyo, Tokyo, Japan
BJU Int 93:1009-13. 2004..CONCLUSION: These analyses confirm the psychometric properties and clinical validity of the short-form KHQ, which appears to offer a practical, valid and reliable health-related quality-of-life instrument... - Maximum tumor diameter: a simple independent predictor for biochemical recurrence after radical prostatectomyH Fukuhara
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Prostate Cancer Prostatic Dis 13:244-7. 2010..MTD would be a useful tool for predicting BCR, as calculation of MTD is a simple and reliable measure... - Comparison of the distribution patterns of BK polyomavirus lineages among China, Korea and Japan: implications for human migrations in northeast AsiaShan Zhong
Department of Urology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
Microbiol Immunol 53:266-76. 2009..Most of the JCV-based inferences of northeastern Asian migrations were consistent with those based on BKV, but the previously suggested migration route from the Asian continent to the Japanese archipelago seemed to need revision... - Reproducibility of cystometry in overactive detrusorY Homma
Department of Urology, Tokyo University Hospital, Tokyo, Japan
Eur Urol 38:681-5. 2000..To examine the reproducibility of cystometry in the overactive detrusor... - A prospective and randomized study of primary hormonal therapy for patients with localized or locally advanced prostate cancer unsuitable for radical prostatectomy: results of the 5-year follow-upH Akaza
Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
BJU Int 91:33-6. 2003..To evaluate the effect of primary hormonal therapy for patients with localized and locally advanced prostate cancer... - Brain response provoked by different bladder volumes: a near infrared spectroscopy studyShinya Matsumoto
Department of Urology, Shinmatsudo Central General Hospital, Matsudo shi, Chiba, Japan
Neurourol Urodyn 30:529-35. 2011..In order to understand frontal lobe responses in bladder sensation in healthy subjects, we examined the cortical localization of response to the different bladder volumes... - Evolution of the BK polyomavirus: epidemiological, anthropological and clinical implicationsYoshiaki Yogo
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Rev Med Virol 19:185-99. 2009..In this review, we describe these findings and discuss their epidemiological, anthropological and clinical implications... - Near infrared spectroscopy study of the central nervous activity during artificial changes in bladder sensation in menShinya Matsumoto
Department of Urology, The University of Tokyo Hospital, Bunkyo ku, Tokyo, Japan
Int J Urol 16:760-4. 2009..To investigate the regional specificity of multi-channel near infrared spectroscopy (NIRS) on the detection of urination-related cortical activation in healthy men... - Ribonucleotide reductase M2 subunit is a novel diagnostic marker and a potential therapeutic target in bladder cancerTeppei Morikawa
Department of Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
Histopathology 57:885-92. 2010..To examine the immunohistochemical expression and function of ribonucleotide reductase M2 subunit (RRM2), a gemcitabine-related molecule, in bladder cancer... - Effects of castration on contraction and alpha(1)-adrenoceptor expression in rat prostateY Homma
Department of Urology, Tokyo University Branch Hospital, 3 28 6 Mejirodai, Bunkyo ku, Tokyo 112 8688, Japan
Br J Pharmacol 131:1454-60. 2000.... - Long-term outcome of endoscopic biopsy and subsequent nephroureterectomy for upper urinary tract tumorS Minowada
Department of Urology, Faculty of Medicine, The University of Tokyo, Japan
Int J Urol 8:6-9. 2001..Upper urinary tract tumors can be biopsied using a flexible ureterorenoscope. This study examined retrospectively possible adverse effects of this procedure on patient outcome... - A randomized, double-blind, placebo-controlled phase II dose-finding study of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladderYukio Homma
Department of Urology, University of Tokyo, Tokyo, Japan
Int J Urol 15:809-15. 2008..To evaluate the efficacy, safety/tolerability, and dose-response relationship of imidafenacin in Japanese patients with overactive bladder... - [Evaluation of psychometric properties of Japanese version of international prostate symptom score and BPH impact index]Yukio Homma
Department of Urology, University of Tokyo
Nippon Hinyokika Gakkai Zasshi 94:560-9. 2003..CONCLUSION: Japanese translations of IPSS and BII were shown to be reliable, valid and one-dimensional instruments in the Japanese patients. They would be equivalent to the original English questionnaires... - Multidisciplinary treatment of advanced testicular tumor with bulky liver metastasisS Minowada
Department of Urology, Faculty of Medicine, University of Tokyo, Japan
Urol Int 67:178-80. 2001..The efficient combination treatment normalized the tumor markers within 6 months and has maintained complete serological remission for 4.7 years... - miR-148a is an androgen-responsive microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expressionT Murata
Department of Anti Aging Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
Prostate Cancer Prostatic Dis 13:356-61. 2010..CAND1 knockdown by small interfering RNA promoted the proliferation of LNCaP cells. Our study indicates the potential contribution of miR-148a to the growth of human prostate cancer... - Cancer-related pain and quality of life in prostate cancer patients: assessment using the Functional Assessment of Prostate Cancer TherapyTetsuya Fujimura
Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 16:522-5. 2009..Combined use of FACT and pain scales enhances the objective assessment of QOL and pain status in PC patients. Control of disease-associated pain is crucial to improving QOL in stage D2 PC patients... - Power Doppler ultrasonography-directed prostate biopsy in men with elevated serum PSA levels: an evaluation of the clinical utility and limitationsSatoru Takahashi
Department of Urology, University of Tokyo Faculty of Medicine, Tokyo, Japan
Urology 60:248-52. 2002..However, PDU-directed biopsy does not appear to identify prostate cancer with sufficient accuracy to omit the systematic biopsy, and combined use of these methods should be preferable... - Efficacy of primary hormone therapy for localized or locally advanced prostate cancer: results of a 10-year follow-upHideyuki Akaza
Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan
BJU Int 98:573-9. 2006.... - [Clinical diagnosis of benign prostatic hyperplasia]Yukio Homma
Department of Urology, Tokyo University Hospital
Nippon Rinsho 60:327-32. 2002 - A pilot study evaluating a new questionnaire for prostatic symptom scoring, the SPSS, and its sensitivity as constructed to objective measures of outflow obstructionMasataka Yano
Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital, Koshigaya City, Japan
Int J Urol 11:288-94. 2004..However, there are still several aspects of the SPSS which need to be improved upon, and the questionnaire should be studied in larger numbers of patients suffering from lower urinary tract symptoms... - Importance of fatty acid substituents of chemically synthesized lipid A-subunit analogs in the expression of immunopharmacological activityY Kumazawa
School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan
Infect Immun 56:149-55. 1988..The importance of fatty acid substituents, including stereospecificity for the expression of immunopharmacological activities of 4-O-phosphono-D-glucosamine derivatives, was demonstrated... - Noninvasive detection and prediction of bladder cancer by fluorescence in situ hybridization analysis of exfoliated urothelial cells in voided urineS Ishiwata
Department of Urology, University of Tokyo Faculty of Medicine, Tokyo, Japan
Urology 57:811-5. 2001..015). CONCLUSIONS: These findings suggest that FISH analysis of exfoliated urothelial cells in voided urine can efficiently detect bladder cancer and predict its recurrence... - Age-related changes in cholinergic and purinergic neurotransmission in human isolated bladder smooth musclesM Yoshida
Department of Urology, Kumamoto University School of Medicine, 1 1 1 Honjo, 860 8556, Kumamoto, Japan
Exp Gerontol 36:99-109. 2001..The age-related changes in neurotransmissions may contribute to the changes in bladder function in the elderly... - Incidence and clinical features of priapism in Japan: 46 cases from the Japanese diagnosis procedure combination database 2006-2008T Sugihara
School of Public Health, The University of Tokyo, Tokyo, Japan
Int J Impot Res 23:76-80. 2011..The incidence was estimated to be 0.13 (95% confidence interval, 0.097-0.17) per 100,000 person-years. This incidence was lower than that reported in other parts of the world... - Efficacy of low dose tamsulosin in medical expulsive therapy for ureteral stones in Japanese male patients: a randomized controlled studyTomoyuki Kaneko
Department of Urology, Tokyo Metropolitan Police Hospital, Tokyo, Japan
Int J Urol 17:462-5. 2010..To evaluate the efficacy of low dose tamsulosin for facilitating spontaneous passage of ureteral stones in Japanese male patients... - Treatment of patients with superficial bladder cancer by intravesical instillation of anticancer drugs plus oral chemotherapy following TUR-Bt: a randomized controlled trialHisashi Matsushima
Department of Urology, Tokyo Metropolitan Police Hospital 10 41, Chiyoda ku, Tokyo 102 0071, Japan
Oncol Rep 9:283-8. 2002..These findings suggested 5'-DFUR showed a mild efficacy in patients with higher TP levels and that patients with higher TP levels resulted in poorer prognosis... - Silodosin, a new alpha1A-adrenoceptor-selective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo-controlled, double-blind study in Japanese menKazuki Kawabe
Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
BJU Int 98:1019-24. 2006..9%) discontinued treatment for abnormal ejaculation. CONCLUSION: Silodosin was generally effective in the absence of obtrusive side-effects. This study suggests that silodosin is clinically useful for treating LUTS associated with BPH... - [Linguistic validation of Japanese version of International Prostate Symptom Score and BPH impact index]Yukio Homma
Department of Urology, University of Tokyo
Nippon Hinyokika Gakkai Zasshi 93:669-80. 2002..CONCLUSION: We evaluated linguistic validity of Japanese translations of IPSS and BII, and proposed a valid Japanese version of these questionnaires... - Expression of cytochrome P450 3A4 and its clinical significance in human prostate cancerTetsuya Fujimura
Department of Urology, University of Tokyo, Japan
Urology 74:391-7. 2009..We previously reported that CYP2B6 is a growth-inhibitory and prognostic factor in human PCa; however, the status of CYP3A4 in PCa remains unclear... - Polymorphism of cytochrome P450 2B6 and prostate cancer risk: a significant association in a Japanese populationTakayuki Kurosaki
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 16:364-8. 2009..To explore whether Lys262Arg polymorphism of the Cytochrome P450 2B6 (CYP2B6) gene could act as a genetic marker for prostate cancer risk among Japanese men... - The clinical significance of the urodynamic investigation in incontinenceY Homma
Department of Urology, Tokyo University Hospital, Japan
BJU Int 90:489-97. 2002 - Uroplakin III-delta4 messenger RNA as a promising marker to identify nonulcerative interstitial cystitisYu Zeng
Department of Urology, Kagawa University Faculty of Medicine, Kagawa, Japan
J Urol 178:1322-7; discussion 1327. 2007..Uroplakins that are expressed by urothelial cells are thought to have an important role as major barrier proteins on the apical surface of the urothelium... - Transient anuria requiring nephrostomy after intravesical bacillus Calmette-Guérin instillations for superficial bladder cancerTomoyuki Kaneko
Department of Urology, Japanese Red Cross Medical Center, Tokyo, Japan
Int J Urol 13:294-5. 2006..Although BCG intravesical instillation after nephroureterectomy is a common practice, special care should be taken of renal function in patients with unilateral kidney during BCG therapy... - Linkage and microarray analyses of susceptibility genes in ACI/Seg rats: a model for prostate cancers in the agedSatoshi Yamashita
Carcinogenesis Division, National Cancer Center Research Institute, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, Japan
Cancer Res 65:2610-6. 2005..These results showed that prostate cancer susceptibility of ACI rats involves at least four loci, and suggested Mme and Cdkn1a as candidates for Pcr1 and Pcs2... - How frequent are invasive therapies required in patients receiving tamsulosin for benign prostatic hyperplasia? A retrospective long-term studyKazuki Kawabe
Tokyo Teishin Hospital, and Department of Pharmacoepidemiology, Faculty of Medicine, The University of Tokyo, Japan
Int J Urol 13:127-31. 2006.... - Successful treatment of metastatic malignant fibrous histiocytoma of the kidneyToru Sugihara
Department of Urology, Tokyo University Hospital, Tokyo, Japan
Urol Int 85:118-20. 2010..He is now well, and without any evidence of recurrent disease... - Reliability and validity of King's Health Questionnaire in patients with symptoms of overactive bladder with urge incontinence in JapanShinichi Uemura
Juntendo University Graduate School of Medicine, Hongo, Tokyo, Japan
Neurourol Urodyn 23:94-100. 2004..The purpose of this study is to evaluate the psychometric properties of the Japanese version of the King's Health Questionnaire (KHQ) in patients with symptoms of overactive bladder (OAB) with urge incontinence... - Defining overactive bladder as hypersensitivityOsamu Yamaguchi
Department of Urology, Fukushima Medical University, Fukushima, Japan
Neurourol Urodyn 26:904-7. 2007..This hypersensitivity was observed in our patients regardless of urgency episodes. We therefore hypothesized that OAB may be more accurately defined as a hypersensitivity disorder rather than a syndrome characterized by urgency... - Three-dimensional computer-controlled acoustic pressure scanning and quantification of focused ultrasoundJoonho Seo
School of Engineering, The University of Tokyo, Hongo, Tokyo, Japan
IEEE Trans Ultrason Ferroelectr Freq Control 57:883-91. 2010.... - Significance of nocturia in the International Prostate Symptom Score for benign prostatic hyperplasiaYukio Homma
Department of Urology, Tokyo University, Tokyo, Japan
J Urol 167:172-6. 2002..CONCLUSIONS: The nocturia score of the International Prostate Symptom Score behaves differently in the symptom complex of BPH in Japanese men, partially because it is most confounded by the aging factor... - Oncolytic virus therapy for prostate cancerHiroshi Fukuhara
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 17:20-30. 2010..The result shows the oncolytic virus therapy is promising toward clinical application. Here, we review the recent advances in the field and summarize the results from clinical trials... - Distant metastasis of renal cell carcinoma with a diameter of 3 cm or less-which is aggressive cancer?Haruki Kume
Department of Urology, Tokyo University Hospital, Tokyo, Japan
J Urol 184:64-8. 2010..However, metastasis develops in a small number of cases, which cannot be ignored. We investigated the clinicopathological characters of small renal cell carcinoma with metastasis to further understand this condition... - CXCR3 binding chemokine and TNFSF14 over expression in bladder urothelium of patients with ulcerative interstitial cystitisTeruyuki Ogawa
Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan
J Urol 183:1206-12. 2010..We investigated the genes responsible for ulcerative interstitial cystitis by DNA microarray analysis and quantitative real-time polymerase chain reaction... - Differential expression of estrogen-related receptors beta and gamma (ERRbeta and ERRgamma) and their clinical significance in human prostate cancerTetsuya Fujimura
Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
Cancer Sci 101:646-51. 2010..0003). We demonstrated the differential expression of ERRbeta and ERRgamma in prostate tissue. The combined evaluation of the expression of ERRalpha and ERRgamma could be a significant prognostic factor for prostate cancer... - The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: pathophysiology and pharmacotherapy of overactive bladderMasaki Yoshida
Department of Urology, Kumamoto Hospital of Japan Labor Health and Welfare Organization, 1670 Takehara cho, Yatsushiro City, Kumamoto 866 8533, Japan
J Pharmacol Sci 112:128-34. 2010..In this review, the pathophysiology of OAB, especially the role of non-neuronal acetylcholine, is discussed. In addition, new drugs with new action mechanisms will be introduced... - Estrogen receptor-binding fragment-associated gene 9 expression and its clinical significance in human testicular cancerTetsuya Fujimura
Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
Int J Urol 16:329-32. 2009..2005; 65: 3700). Here, we evaluated EBAG9 expression and its clinical significance in normal and malignant human testicular tissues... - Long-term safety, tolerability and efficacy of extended-release tolterodine in the treatment of overactive bladder in Japanese patientsMineo Takei
Harasanshin General Hospital, Fukuoka, Japan
Int J Urol 12:456-64. 2005..7% reported treatment benefit. CONCLUSIONS: Favorable safety, tolerability and efficacy of once-daily tolterodine ER was maintained over 12 months in a Japanese overactive bladder patient population... - [Clinical experience on 52 patients with interstitial cystitis]Tomoyuki Kaneko
Department of Urology, Japanese Red Cross Medical Center
Nippon Hinyokika Gakkai Zasshi 97:771-6. 2006..64%). CONCLUSIONS: IC patients suffered from severe symptoms for a long time without correct diagnosis or proper treatments. Hydrodistension was effective for IC patients, especially for ulcer type, combined with TUC...