Y Homma

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi request reprint Radical prostatectomy and adjuvant endocrine therapy for prostate cancer with or without preoperative androgen deprivation: Five-year results
    Yukio Homma
    Department of Urology, University of Tokyo, Tokyo, Japan
    Int J Urol 11:295-303. 2004
  2. ncbi request reprint Minimal clinically important change in urinary incontinence detected by a quality of life assessment tool in overactive bladder syndrome with urge incontinence
    Yukio Homma
    Department of Urology, Japanese Red Cross Medical Center, Tokyo, Japan
    Neurourol Urodyn 25:228-35. 2006
  3. doi request reprint Transcriptional control region rearrangements associated with the evolution of JC polyomavirus
    Yoshiaki Yogo
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Virology 380:118-23. 2008
  4. doi request reprint Psychometric validation of the Japanese version of the International Consultation on Incontinence Questionnaire-Short Form
    Momokazu Gotoh
    Department of Urology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Int J Urol 16:303-6. 2009
  5. doi request reprint Assessment of overactive bladder symptoms: comparison of 3-day bladder diary and the overactive bladder symptoms score
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Urology 77:60-4. 2011
  6. pmc Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men
    Miao Liu
    Department of Urology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    BMC Genet 10:37. 2009
  7. ncbi request reprint Clinical efficacy and tolerability of extended-release tolterodine and immediate-release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo-controlled trial
    Y Homma
    Department of Urology, Tokyo University, Tokyo, Japan
    BJU Int 92:741-7. 2003
  8. doi request reprint Symptom severity and patient perceptions in overactive bladder: how are they related?
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Japan
    BJU Int 104:968-72. 2009
  9. ncbi request reprint Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostate
    Yukio Homma
    Department of Urology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Carcinogenesis 25:1011-4. 2004
  10. doi request reprint Japanese guideline for diagnosis and treatment of interstitial cystitis
    Yukio Homma
    Department of Urology, Tokyo University Graduate School of Medicine, Tokyo
    Int J Urol 16:4-16. 2009

Collaborators

Detail Information

Publications77

  1. ncbi request reprint Radical prostatectomy and adjuvant endocrine therapy for prostate cancer with or without preoperative androgen deprivation: Five-year results
    Yukio Homma
    Department of Urology, University of Tokyo, Tokyo, Japan
    Int J Urol 11:295-303. 2004
    ..The effects of preoperative androgen deprivation on the outcomes of prostate cancer patients who received radical prostatectomy and subsequent adjuvant endocrine therapy have not yet been fully evaluated...
  2. ncbi request reprint Minimal clinically important change in urinary incontinence detected by a quality of life assessment tool in overactive bladder syndrome with urge incontinence
    Yukio Homma
    Department of Urology, Japanese Red Cross Medical Center, Tokyo, Japan
    Neurourol Urodyn 25:228-35. 2006
    ....
  3. doi request reprint Transcriptional control region rearrangements associated with the evolution of JC polyomavirus
    Yoshiaki Yogo
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Virology 380:118-23. 2008
    ..This observation suggests that during the course of JCV evolution, JCV strains with sporadic rearrangements became predominant over archetypal TCRs in some JCV lineages or sub-lineages...
  4. doi request reprint Psychometric validation of the Japanese version of the International Consultation on Incontinence Questionnaire-Short Form
    Momokazu Gotoh
    Department of Urology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
    Int J Urol 16:303-6. 2009
    ..To evaluate the psychometric properties of the Japanese version of the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF)...
  5. doi request reprint Assessment of overactive bladder symptoms: comparison of 3-day bladder diary and the overactive bladder symptoms score
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Urology 77:60-4. 2011
    ..To compare the Overactive Bladder Symptom Score (OABSS) and a bladder diary as a tool for assessing symptoms of overactive bladder (OAB)...
  6. pmc Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men
    Miao Liu
    Department of Urology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    BMC Genet 10:37. 2009
    ..Here, we evaluated whether the single-nucleotide polymorphisms rs1447295 and rs6983267 were associated with the risk of sporadic prostate cancer as well as latent prostate cancer in a native Japanese population...
  7. ncbi request reprint Clinical efficacy and tolerability of extended-release tolterodine and immediate-release oxybutynin in Japanese and Korean patients with an overactive bladder: a randomized, placebo-controlled trial
    Y Homma
    Department of Urology, Tokyo University, Tokyo, Japan
    BJU Int 92:741-7. 2003
    ..To compare extended-release (ER) tolterodine and immediate-release (IR) oxybutynin with placebo in Japanese and Korean patients with an overactive bladder (OAB)...
  8. doi request reprint Symptom severity and patient perceptions in overactive bladder: how are they related?
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Japan
    BJU Int 104:968-72. 2009
    ..To assess the relationship between symptom severity and patient perceptions in patients with overactive bladder (OAB), as estimated by OAB Symptom Score (OABSS) and patient-reported outcome measures, respectively...
  9. ncbi request reprint Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostate
    Yukio Homma
    Department of Urology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Carcinogenesis 25:1011-4. 2004
    ..The role of dietary fat and oxidative stress in prostate carcinogenesis needs further investigation...
  10. doi request reprint Japanese guideline for diagnosis and treatment of interstitial cystitis
    Yukio Homma
    Department of Urology, Tokyo University Graduate School of Medicine, Tokyo
    Int J Urol 16:4-16. 2009
    ..This article is the English translation of a shortened version of the Guideline for convenience of readers worldwide...
  11. ncbi request reprint Endocrine therapy with or without radical prostatectomy for T1b-T3N0M0 prostate cancer
    Yukio Homma
    Department of Urology, University of Tokyo, Tokyo, Japan
    Int J Urol 11:218-24. 2004
    ..We retrospectively compared the 5-year survival rates of T1b-T3N0M0 prostate cancer patients treated either by endocrine therapy plus radical prostatectomy or endocrine therapy alone...
  12. ncbi request reprint Should an antimuscarinic agent be used for persistent LUTS after treatment with an alpha(1)-blocker?
    Yukio Homma
    Department of Urology, Tokyo University Graduate School of Medicine, Tokyo, Japan
    Nat Clin Pract Urol 6:66-7. 2009
    ..Better evaluation of storage symptoms might facilitate the more-appropriate use of combined treatment in this setting...
  13. ncbi request reprint Health-related quality of life of Japanese patients with overactive bladder treated with extended-release tolterodine or immediate-release oxybutynin: a randomized, placebo-controlled trial
    Y Homma
    Department of Urology, Tokyo University Hospital, 7 3 1 Hongo Bunkyo ku, 113 8655 Tokyo, Japan
    World J Urol 22:251-6. 2004
    ..Our findings demonstrate that Japanese OAB patients receiving tolterodine ER or oxybutynin experienced overall improvement in their quality of life...
  14. doi request reprint Long-term safety, tolerability, and efficacy of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder
    Yukio Homma
    Department of Urology, University of Tokyo, Tokyo, Japan
    Int J Urol 15:986-91. 2008
    ..To evaluate the long-term safety, tolerability, and efficacy of imidafenacin, a novel anti-muscarinic agent, in Japanese patients with overactive bladder...
  15. ncbi request reprint Classification of nocturia in the adult and elderly patient: a review of clinical criteria and selected literature
    Yukio Homma
    Division of Urology, Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
    BJU Int 96:8-14. 2005
    ..The application of valid diagnostic criteria to differentiate the underlying cause of nocturia should help lead to more appropriate and effective management of this pervasive problem...
  16. ncbi request reprint An epidemiological survey of overactive bladder symptoms in Japan
    Yukio Homma
    Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
    BJU Int 96:1314-8. 2005
    ....
  17. doi request reprint Core Lower Urinary Tract Symptom score (CLSS) questionnaire: a reliable tool in the overall assessment of lower urinary tract symptoms
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 15:816-20. 2008
    ..To identify the symptoms of higher relevance in patients complaining of lower urinary tract symptoms (LUTS)...
  18. doi request reprint Lower urinary tract symptomatology: Its definition and confusion
    Yukio Homma
    Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
    Int J Urol 15:35-43. 2008
    ..This review has detailed definitions and confusions related to the latest version, and suggested possible solutions for a better vocabulary of words...
  19. ncbi request reprint Symptom assessment tool for overactive bladder syndrome--overactive bladder symptom score
    Yukio Homma
    Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
    Urology 68:318-23. 2006
    ..Overactive bladder (OAB) is a common symptom syndrome with urgency, urinary frequency, and urgency incontinence. To collectively express OAB symptoms, we developed the overactive bladder symptom score (OABSS)...
  20. doi request reprint A randomized, double-blind, placebo- and propiverine-controlled trial of the novel antimuscarinic agent imidafenacin in Japanese patients with overactive bladder
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 16:499-506. 2009
    ..To compare the efficacy and tolerability of imidafenacin, a novel antimuscarinic agent, with propiverine and a placebo in Japanese patients with overactive bladder (OAB)...
  21. ncbi request reprint Epidemiologic survey of lower urinary tract symptoms in Japan
    Yukio Homma
    Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan
    Urology 68:560-4. 2006
    ..A large-scale nationwide epidemiologic survey was performed to determine the prevalence of lower urinary tract symptoms (LUTS) and their impact on health-related quality of life (HRQOL) in Japan...
  22. doi request reprint Ejaculation disorder is associated with increased efficacy of silodosin for benign prostatic hyperplasia
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Urology 76:1446-50. 2010
    ..To provide clinical evidence that ejaculation disorder caused by selective alpha(1A)-blockers may be associated with larger symptomatic improvements in patients with benign prostatic hyperplasia...
  23. doi request reprint Clinical guideline for male lower urinary tract symptoms
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 16:775-90. 2009
    ..Treatment with anticholinergic agents should be reserved only for urologists, considering the risk of urinary retention. The present guideline should help urologists and especially non-urologists treat men with LUTS...
  24. doi request reprint Outline of JUA clinical guidelines for benign prostatic hyperplasia
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 18:741-56. 2011
    ..Surgical intervention is indicated when non-surgical treatments fail to provide sufficient symptomatic relief and bladder outlet obstruction is highly suspected...
  25. ncbi request reprint Voiding and incontinence frequencies: variability of diary data and required diary length
    Yukio Homma
    Department of Urology, Tokyo University, Tokyo, Japan
    Neurourol Urodyn 21:204-9. 2002
    ..However, the diary length should be extended in a patient with rarer events of incontinence, and it should be shortened for those who are incontinent more often or who are diagnosed with voiding frequency only...
  26. doi request reprint Clinical guidelines for interstitial cystitis and hypersensitive bladder syndrome
    Yukio Homma
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Bunkyoku, Tokyo, Japan
    Int J Urol 16:597-615. 2009
    ..The inclusion and efficacy criteria for clinical trials should be standardized to enhance the clinical research for this disabling disease, which has proved to be more prevalent than previously believed...
  27. ncbi request reprint Early results of radical prostatectomy and adjuvant endocrine therapy for prostate cancer with or without preoperative androgen deprivation. The Prostate Cancer Study Group
    Y Homma
    Department of Urology, University of Tokyo, Japan
    Int J Urol 6:229-37; discussion 238-9. 1999
    ..The effects of preoperative androgen deprivation were explored in the patients who received radical prostatectomy and subsequent adjuvant endocrine therapy for prostate cancer...
  28. ncbi request reprint Early results of LH-RH agonist treatment with or without chlormadinone acetate for hormone therapy of naive localized or locally advanced prostate cancer: a prospective and randomized study. The Prostate Cancer Study Group
    H Akaza
    Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    Jpn J Clin Oncol 30:131-6. 2000
    ..In this situation, primary hormone therapy is an alternative treatment option. We have designed a prospective randomized study of the effects of primary hormone therapy for such patients...
  29. doi request reprint Lower incidence of inguinal hernia after radical prostatectomy using open gasless endoscopic single-site surgery
    H Fukuhara
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Prostate Cancer Prostatic Dis 14:162-5. 2011
    ..The hernia-free survival was significantly higher after MIES-RRP than after conventional RRP (P=0.037). Our results suggest that MIES-RRP is less associated with post-operative inguinal hernia than conventional RRP...
  30. ncbi request reprint Use of the short form of King's Health Questionnaire to measure quality of life in patients with an overactive bladder
    Y Homma
    Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    BJU Int 93:1009-13. 2004
    ..To develop a short version of the King's Health Questionnaire (KHQ), as there is a practical need to have a shorter version to summarize the eight domain scores into fewer domains...
  31. doi request reprint Maximum tumor diameter: a simple independent predictor for biochemical recurrence after radical prostatectomy
    H Fukuhara
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Prostate Cancer Prostatic Dis 13:244-7. 2010
    ..MTD would be a useful tool for predicting BCR, as calculation of MTD is a simple and reliable measure...
  32. doi request reprint Comparison of the distribution patterns of BK polyomavirus lineages among China, Korea and Japan: implications for human migrations in northeast Asia
    Shan Zhong
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
    Microbiol Immunol 53:266-76. 2009
    ..Most of the JCV-based inferences of northeastern Asian migrations were consistent with those based on BKV, but the previously suggested migration route from the Asian continent to the Japanese archipelago seemed to need revision...
  33. ncbi request reprint Reproducibility of cystometry in overactive detrusor
    Y Homma
    Department of Urology, Tokyo University Hospital, Tokyo, Japan
    Eur Urol 38:681-5. 2000
    ..To examine the reproducibility of cystometry in the overactive detrusor...
  34. ncbi request reprint A prospective and randomized study of primary hormonal therapy for patients with localized or locally advanced prostate cancer unsuitable for radical prostatectomy: results of the 5-year follow-up
    H Akaza
    Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    BJU Int 91:33-6. 2003
    ..To evaluate the effect of primary hormonal therapy for patients with localized and locally advanced prostate cancer...
  35. doi request reprint Brain response provoked by different bladder volumes: a near infrared spectroscopy study
    Shinya Matsumoto
    Department of Urology, Shinmatsudo Central General Hospital, Matsudo shi, Chiba, Japan
    Neurourol Urodyn 30:529-35. 2011
    ..In order to understand frontal lobe responses in bladder sensation in healthy subjects, we examined the cortical localization of response to the different bladder volumes...
  36. doi request reprint Evolution of the BK polyomavirus: epidemiological, anthropological and clinical implications
    Yoshiaki Yogo
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Rev Med Virol 19:185-99. 2009
    ..In this review, we describe these findings and discuss their epidemiological, anthropological and clinical implications...
  37. doi request reprint Near infrared spectroscopy study of the central nervous activity during artificial changes in bladder sensation in men
    Shinya Matsumoto
    Department of Urology, The University of Tokyo Hospital, Bunkyo ku, Tokyo, Japan
    Int J Urol 16:760-4. 2009
    ..To investigate the regional specificity of multi-channel near infrared spectroscopy (NIRS) on the detection of urination-related cortical activation in healthy men...
  38. doi request reprint Ribonucleotide reductase M2 subunit is a novel diagnostic marker and a potential therapeutic target in bladder cancer
    Teppei Morikawa
    Department of Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Histopathology 57:885-92. 2010
    ..To examine the immunohistochemical expression and function of ribonucleotide reductase M2 subunit (RRM2), a gemcitabine-related molecule, in bladder cancer...
  39. pmc Effects of castration on contraction and alpha(1)-adrenoceptor expression in rat prostate
    Y Homma
    Department of Urology, Tokyo University Branch Hospital, 3 28 6 Mejirodai, Bunkyo ku, Tokyo 112 8688, Japan
    Br J Pharmacol 131:1454-60. 2000
    ....
  40. ncbi request reprint Long-term outcome of endoscopic biopsy and subsequent nephroureterectomy for upper urinary tract tumor
    S Minowada
    Department of Urology, Faculty of Medicine, The University of Tokyo, Japan
    Int J Urol 8:6-9. 2001
    ..Upper urinary tract tumors can be biopsied using a flexible ureterorenoscope. This study examined retrospectively possible adverse effects of this procedure on patient outcome...
  41. doi request reprint A randomized, double-blind, placebo-controlled phase II dose-finding study of the novel anti-muscarinic agent imidafenacin in Japanese patients with overactive bladder
    Yukio Homma
    Department of Urology, University of Tokyo, Tokyo, Japan
    Int J Urol 15:809-15. 2008
    ..To evaluate the efficacy, safety/tolerability, and dose-response relationship of imidafenacin in Japanese patients with overactive bladder...
  42. ncbi request reprint [Evaluation of psychometric properties of Japanese version of international prostate symptom score and BPH impact index]
    Yukio Homma
    Department of Urology, University of Tokyo
    Nihon Hinyokika Gakkai Zasshi 94:560-9. 2003
    ..To evaluate psychometric properties of the Japanese version of International Prostate Symptom Score (IPSS) and BPH Impact Index (BII)...
  43. ncbi request reprint Multidisciplinary treatment of advanced testicular tumor with bulky liver metastasis
    S Minowada
    Department of Urology, Faculty of Medicine, University of Tokyo, Japan
    Urol Int 67:178-80. 2001
    ..The efficient combination treatment normalized the tumor markers within 6 months and has maintained complete serological remission for 4.7 years...
  44. doi request reprint miR-148a is an androgen-responsive microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expression
    T Murata
    Department of Anti Aging Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Prostate Cancer Prostatic Dis 13:356-61. 2010
    ..CAND1 knockdown by small interfering RNA promoted the proliferation of LNCaP cells. Our study indicates the potential contribution of miR-148a to the growth of human prostate cancer...
  45. doi request reprint Cancer-related pain and quality of life in prostate cancer patients: assessment using the Functional Assessment of Prostate Cancer Therapy
    Tetsuya Fujimura
    Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 16:522-5. 2009
    ..Combined use of FACT and pain scales enhances the objective assessment of QOL and pain status in PC patients. Control of disease-associated pain is crucial to improving QOL in stage D2 PC patients...
  46. ncbi request reprint Power Doppler ultrasonography-directed prostate biopsy in men with elevated serum PSA levels: an evaluation of the clinical utility and limitations
    Satoru Takahashi
    Department of Urology, University of Tokyo Faculty of Medicine, Tokyo, Japan
    Urology 60:248-52. 2002
    ..To determine the utility and limitations of power Doppler ultrasonography (PDU)-directed prostate biopsy in patients with elevated serum prostate-specific antigen (PSA) levels...
  47. ncbi request reprint Efficacy of primary hormone therapy for localized or locally advanced prostate cancer: results of a 10-year follow-up
    Hideyuki Akaza
    Department of Urology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan
    BJU Int 98:573-9. 2006
    ....
  48. ncbi request reprint [Clinical diagnosis of benign prostatic hyperplasia]
    Yukio Homma
    Department of Urology, Tokyo University Hospital
    Nihon Rinsho 60:327-32. 2002
  49. ncbi request reprint A pilot study evaluating a new questionnaire for prostatic symptom scoring, the SPSS, and its sensitivity as constructed to objective measures of outflow obstruction
    Masataka Yano
    Department of Urology, Dokkyo University School of Medicine, Koshigaya Hospital, Koshigaya City, Japan
    Int J Urol 11:288-94. 2004
    ....
  50. pmc Importance of fatty acid substituents of chemically synthesized lipid A-subunit analogs in the expression of immunopharmacological activity
    Y Kumazawa
    School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan
    Infect Immun 56:149-55. 1988
    ..The importance of fatty acid substituents, including stereospecificity for the expression of immunopharmacological activities of 4-O-phosphono-D-glucosamine derivatives, was demonstrated...
  51. ncbi request reprint Noninvasive detection and prediction of bladder cancer by fluorescence in situ hybridization analysis of exfoliated urothelial cells in voided urine
    S Ishiwata
    Department of Urology, University of Tokyo Faculty of Medicine, Tokyo, Japan
    Urology 57:811-5. 2001
    ..015). CONCLUSIONS: These findings suggest that FISH analysis of exfoliated urothelial cells in voided urine can efficiently detect bladder cancer and predict its recurrence...
  52. ncbi request reprint Age-related changes in cholinergic and purinergic neurotransmission in human isolated bladder smooth muscles
    M Yoshida
    Department of Urology, Kumamoto University School of Medicine, 1 1 1 Honjo, 860 8556, Kumamoto, Japan
    Exp Gerontol 36:99-109. 2001
    ..The age-related changes in neurotransmissions may contribute to the changes in bladder function in the elderly...
  53. doi request reprint Incidence and clinical features of priapism in Japan: 46 cases from the Japanese diagnosis procedure combination database 2006-2008
    T Sugihara
    School of Public Health, The University of Tokyo, Tokyo, Japan
    Int J Impot Res 23:76-80. 2011
    ..The incidence was estimated to be 0.13 (95% confidence interval, 0.097-0.17) per 100,000 person-years. This incidence was lower than that reported in other parts of the world...
  54. doi request reprint Efficacy of low dose tamsulosin in medical expulsive therapy for ureteral stones in Japanese male patients: a randomized controlled study
    Tomoyuki Kaneko
    Department of Urology, Tokyo Metropolitan Police Hospital, Tokyo, Japan
    Int J Urol 17:462-5. 2010
    ..To evaluate the efficacy of low dose tamsulosin for facilitating spontaneous passage of ureteral stones in Japanese male patients...
  55. ncbi request reprint Treatment of patients with superficial bladder cancer by intravesical instillation of anticancer drugs plus oral chemotherapy following TUR-Bt: a randomized controlled trial
    Hisashi Matsushima
    Department of Urology, Tokyo Metropolitan Police Hospital 10 41, Chiyoda ku, Tokyo 102 0071, Japan
    Oncol Rep 9:283-8. 2002
    ..These findings suggested 5'-DFUR showed a mild efficacy in patients with higher TP levels and that patients with higher TP levels resulted in poorer prognosis...
  56. ncbi request reprint Silodosin, a new alpha1A-adrenoceptor-selective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo-controlled, double-blind study in Japanese men
    Kazuki Kawabe
    Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    BJU Int 98:1019-24. 2006
    ..To verify the efficacy and safety of the new alpha1A-adrenoceptor-selective antagonist silodosin compared with tamsulosin and placebo in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)...
  57. ncbi request reprint [Linguistic validation of Japanese version of International Prostate Symptom Score and BPH impact index]
    Yukio Homma
    Department of Urology, University of Tokyo
    Nihon Hinyokika Gakkai Zasshi 93:669-80. 2002
    ..To evaluate linguistic validity of the Japanese version of International Prostate Symptom Score (IPSS) and BPH Impact Index (BII)...
  58. doi request reprint Expression of cytochrome P450 3A4 and its clinical significance in human prostate cancer
    Tetsuya Fujimura
    Department of Urology, University of Tokyo, Japan
    Urology 74:391-7. 2009
    ..We previously reported that CYP2B6 is a growth-inhibitory and prognostic factor in human PCa; however, the status of CYP3A4 in PCa remains unclear...
  59. ncbi request reprint Polymorphism of cytochrome P450 2B6 and prostate cancer risk: a significant association in a Japanese population
    Takayuki Kurosaki
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 16:364-8. 2009
    ..To explore whether Lys262Arg polymorphism of the Cytochrome P450 2B6 (CYP2B6) gene could act as a genetic marker for prostate cancer risk among Japanese men...
  60. ncbi request reprint The clinical significance of the urodynamic investigation in incontinence
    Y Homma
    Department of Urology, Tokyo University Hospital, Japan
    BJU Int 90:489-97. 2002
  61. ncbi request reprint Uroplakin III-delta4 messenger RNA as a promising marker to identify nonulcerative interstitial cystitis
    Yu Zeng
    Department of Urology, Kagawa University Faculty of Medicine, Kagawa, Japan
    J Urol 178:1322-7; discussion 1327. 2007
    ..Uroplakins that are expressed by urothelial cells are thought to have an important role as major barrier proteins on the apical surface of the urothelium...
  62. ncbi request reprint Transient anuria requiring nephrostomy after intravesical bacillus Calmette-Guérin instillations for superficial bladder cancer
    Tomoyuki Kaneko
    Department of Urology, Japanese Red Cross Medical Center, Tokyo, Japan
    Int J Urol 13:294-5. 2006
    ..Although BCG intravesical instillation after nephroureterectomy is a common practice, special care should be taken of renal function in patients with unilateral kidney during BCG therapy...
  63. ncbi request reprint Linkage and microarray analyses of susceptibility genes in ACI/Seg rats: a model for prostate cancers in the aged
    Satoshi Yamashita
    Carcinogenesis Division, National Cancer Center Research Institute, 1 1 Tsukiji 5 chome, Chuo Ku, Tokyo, Japan
    Cancer Res 65:2610-6. 2005
    ..These results showed that prostate cancer susceptibility of ACI rats involves at least four loci, and suggested Mme and Cdkn1a as candidates for Pcr1 and Pcs2...
  64. ncbi request reprint How frequent are invasive therapies required in patients receiving tamsulosin for benign prostatic hyperplasia? A retrospective long-term study
    Kazuki Kawabe
    Tokyo Teishin Hospital, and Department of Pharmacoepidemiology, Faculty of Medicine, The University of Tokyo, Japan
    Int J Urol 13:127-31. 2006
    ....
  65. doi request reprint Successful treatment of metastatic malignant fibrous histiocytoma of the kidney
    Toru Sugihara
    Department of Urology, Tokyo University Hospital, Tokyo, Japan
    Urol Int 85:118-20. 2010
    ..He is now well, and without any evidence of recurrent disease...
  66. ncbi request reprint Reliability and validity of King's Health Questionnaire in patients with symptoms of overactive bladder with urge incontinence in Japan
    Shinichi Uemura
    Juntendo University Graduate School of Medicine, Hongo, Tokyo, Japan
    Neurourol Urodyn 23:94-100. 2004
    ..The purpose of this study is to evaluate the psychometric properties of the Japanese version of the King's Health Questionnaire (KHQ) in patients with symptoms of overactive bladder (OAB) with urge incontinence...
  67. ncbi request reprint Defining overactive bladder as hypersensitivity
    Osamu Yamaguchi
    Department of Urology, Fukushima Medical University, Fukushima, Japan
    Neurourol Urodyn 26:904-7. 2007
    ..This hypersensitivity was observed in our patients regardless of urgency episodes. We therefore hypothesized that OAB may be more accurately defined as a hypersensitivity disorder rather than a syndrome characterized by urgency...
  68. doi request reprint Three-dimensional computer-controlled acoustic pressure scanning and quantification of focused ultrasound
    Joonho Seo
    School of Engineering, The University of Tokyo, Hongo, Tokyo, Japan
    IEEE Trans Ultrason Ferroelectr Freq Control 57:883-91. 2010
    ....
  69. ncbi request reprint Significance of nocturia in the International Prostate Symptom Score for benign prostatic hyperplasia
    Yukio Homma
    Department of Urology, Tokyo University, Tokyo, Japan
    J Urol 167:172-6. 2002
    ..We studied the relationship of nocturia with the International Prostate Symptom Score in men with lower urinary tract symptoms due to benign prostatic hyperplasia (BPH)...
  70. doi request reprint Oncolytic virus therapy for prostate cancer
    Hiroshi Fukuhara
    Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 17:20-30. 2010
    ..The result shows the oncolytic virus therapy is promising toward clinical application. Here, we review the recent advances in the field and summarize the results from clinical trials...
  71. doi request reprint Distant metastasis of renal cell carcinoma with a diameter of 3 cm or less-which is aggressive cancer?
    Haruki Kume
    Department of Urology, Tokyo University Hospital, Tokyo, Japan
    J Urol 184:64-8. 2010
    ..However, metastasis develops in a small number of cases, which cannot be ignored. We investigated the clinicopathological characters of small renal cell carcinoma with metastasis to further understand this condition...
  72. doi request reprint CXCR3 binding chemokine and TNFSF14 over expression in bladder urothelium of patients with ulcerative interstitial cystitis
    Teruyuki Ogawa
    Department of Urology, Shinshu University School of Medicine, Matsumoto, Japan
    J Urol 183:1206-12. 2010
    ..We investigated the genes responsible for ulcerative interstitial cystitis by DNA microarray analysis and quantitative real-time polymerase chain reaction...
  73. doi request reprint Differential expression of estrogen-related receptors beta and gamma (ERRbeta and ERRgamma) and their clinical significance in human prostate cancer
    Tetsuya Fujimura
    Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Cancer Sci 101:646-51. 2010
    ..0003). We demonstrated the differential expression of ERRbeta and ERRgamma in prostate tissue. The combined evaluation of the expression of ERRalpha and ERRgamma could be a significant prognostic factor for prostate cancer...
  74. ncbi request reprint The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: pathophysiology and pharmacotherapy of overactive bladder
    Masaki Yoshida
    Department of Urology, Kumamoto Hospital of Japan Labor Health and Welfare Organization, 1670 Takehara cho, Yatsushiro City, Kumamoto 866 8533, Japan
    J Pharmacol Sci 112:128-34. 2010
    ..In this review, the pathophysiology of OAB, especially the role of non-neuronal acetylcholine, is discussed. In addition, new drugs with new action mechanisms will be introduced...
  75. doi request reprint Estrogen receptor-binding fragment-associated gene 9 expression and its clinical significance in human testicular cancer
    Tetsuya Fujimura
    Department of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan
    Int J Urol 16:329-32. 2009
    ..2005; 65: 3700). Here, we evaluated EBAG9 expression and its clinical significance in normal and malignant human testicular tissues...
  76. ncbi request reprint Long-term safety, tolerability and efficacy of extended-release tolterodine in the treatment of overactive bladder in Japanese patients
    Mineo Takei
    Harasanshin General Hospital, Fukuoka, Japan
    Int J Urol 12:456-64. 2005
    ....
  77. ncbi request reprint [Clinical experience on 52 patients with interstitial cystitis]
    Tomoyuki Kaneko
    Department of Urology, Japanese Red Cross Medical Center
    Nihon Hinyokika Gakkai Zasshi 97:771-6. 2006
    ..To examine clinical features of the patients of interstitial cystitis (IC) undergoing hydrodistension at our institution...