Research Topics
Genomes and GenesSpecies | Masanori HisaokaSummaryAffiliation: University of Occupational and Environmental Health Country: Japan Publications
| Collaborators
|
Detail Information
Publications
Low-grade fibromyxoid sarcoma with prominent giant rosettes and heterotopic ossificationMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Res Pract 208:557-60. 2012..This case, which has such unusual clinicopathologic features, would help to further expand our knowledge regarding the morphologic diversities of low-grade fibromyxoid sarcoma...- Aberrant calreticulin expression is involved in the dedifferentiation of dedifferentiated liposarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Am J Pathol 180:2076-83. 2012..Our results therefore suggest that aberrantly expressed calreticulin in dedifferentiated liposarcoma is involved in its dedifferenitation and/or tumor progression... - Clear cell sarcoma of soft tissue: a clinicopathologic, immunohistochemical, and molecular analysis of 33 casesMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Am J Surg Pathol 32:452-60. 2008..In cases with unusual histologic findings, molecular detection of the EWSR1-ATF1/CREB1 fusion genes provides critical information regarding the diagnosis of the tumor... 
Extraskeletal myxoid chondrosarcoma: updated clinicopathological and molecular genetic characteristicsMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 55:453-63. 2005..Because of its protracted but resilient nature, a tenacious and long-term follow up is necessary for any patient...- Elastofibroma: clonal fibrous proliferation with predominant CD34-positive cellsMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
Virchows Arch 448:195-9. 2006..Thus, these findings suggest that CD34-positive mesenchymal cells are an integral component of elastofibroma, which represents a clonal fibrous proliferation... - Identification of altered MicroRNA expression patterns in synovial sarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Genes Chromosomes Cancer 50:137-45. 2011.... - Aberrant MAD2 expression in soft-tissue sarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 58:329-33. 2008..These data suggest that the aberrant MAD2 expression is potentially associated with pleomorphic morphology and abnormal mitosis in soft-tissue sarcomas, as well as with high-grade tumor progression in its TA subset... - Sebaceous carcinoma of the breast: case report and review of the literatureMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu, 807 8555, and Department of Surgery, Kyushu Rosai Hospital, Kuzuhara, Japan
Virchows Arch 449:484-8. 2006..5, suggesting neuroendocrine differentiation that is a hitherto undescribed phenomenon in the mammary tumors with sebaceous features. This case would expand the morphologic diversity of carcinoma of the breast... - Ossifying synovial sarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
Pathol Res Pract 205:195-8. 2009..The current case suggests the diagnostic utility of the molecular detection of a tumor type-specific fusion gene and expands the phenotypic plasticity of the soft tissue sarcoma of uncertain differentiation... - Expression of estrogen receptors alpha and beta in soft tissue sarcomas: Immunohistochemical and molecular analysisXiao-Qiu Li
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 53:671-9. 2003..The results indicate that both ER isoforms are frequently expressed in certain subsets of soft tissue sarcomas, but their expression levels seem unrelated to the tumor proliferation activity... - Coexpression of NOR1 and SIX3 proteins in extraskeletal myxoid chondrosarcomas without detectable NR4A3 fusion genesMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
Cancer Genet Cytogenet 152:101-7. 2004..Our data suggest that aberrant coexpression of NOR1 and SIX3 is a potential alternative mechanism underlying the development of EMC... - Molecular detection of SS18-SSX fusion gene transcripts by cRNA in situ hybridization in synovial sarcoma using formalin-fixed, paraffin-embedded tumor tissue specimensShuichi Kanemitsu
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Diagn Mol Pathol 16:9-17. 2007..Our results suggest that BT-based ISH can be used as a molecular technique for the detection of SS18-SSX using formalin-fixed, paraffin-embedded tissues... - Molecular detection of FUS-CREB3L2 fusion transcripts in low-grade fibromyxoid sarcoma using formalin-fixed, paraffin-embedded tissue specimensAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Am J Surg Pathol 30:1077-84. 2006..These data suggest that our reverse transcription-polymerase chain reaction assay is a reliable method to detect FUS-CREB3L2, which can thus help in accurately diagnosing LGFMS... - Microtubule-associated protein-2 and class III beta-tubulin are expressed in extraskeletal myxoid chondrosarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Mod Pathol 16:453-9. 2003.... - PLAG1 expression in mesenchymal tumors: an immunohistochemical study with special emphasis on the pathogenetical distinction between soft tissue myoepithelioma and pleomorphic adenoma of the salivary glandAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
Pathol Int 62:1-7. 2012..On the other hand, PLAG1 immunohistochemistry is useful for distinguishing lipoblastoma from other lipomatous tumors including liposarcoma... - Association of microRNA-21 expression with its targets, PDCD4 and TIMP3, in pancreatic ductal adenocarcinomaYuichi Nagao
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Mod Pathol 25:112-21. 2012.... - Primary pulmonary synovial sarcoma: a clinicopathologic, immunohistochemical, and molecular study of 11 casesSumika Okamoto
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Hum Pathol 35:850-6. 2004..5 years. In conclusion, PSS tends to occur in older patients and shows an aggressive behavior probably due to its anatomical location and large tumor often resulting in incomplete resection and high proliferative activity... - Congenital (infantile) pseudarthrosis of the fibula associated with osteofibrous dysplasiaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
Skeletal Radiol 33:545-9. 2004..This case provides further evidence that osteofibrous dysplasia may be associated with congenital (infantile) pseudarthrosis of the lower leg... - DNA-based polymerase chain reaction for detecting FUS-CREB3L2 in low-grade fibromyxoid sarcoma using formalin-fixed, paraffin-embedded tissue specimensAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Diagn Mol Pathol 17:237-40. 2008..Although the sensitivity was not as high as RT-PCR, DNA-based PCR can be used as an alternative molecular approach for detecting the FUS-CREB3L2 fusion gene... - Inflammatory myofibroblastic tumor with predominant anaplastic lymphoma kinase-positive cells lacking a myofibroblastic phenotypeMasanori Hisaoka
Department of Pathology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 53:376-81. 2003..The current findings suggest that ALK-positive cells in IMT are not always myofibroblastic but might be immature primitive mesenchymal cells... - Expression of anaplastic lymphoma kinase in soft tissue tumors: an immunohistochemical and molecular study of 249 casesXiao-Qiu Li
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Hum Pathol 35:711-21. 2004..The current data expands the variety of non-IMT soft tissue tumors with ALK expression, and warrants further investigation of its underlying molecular mechanisms... - TFG is a novel fusion partner of NOR1 in extraskeletal myxoid chondrosarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Genes Chromosomes Cancer 40:325-8. 2004..TFG/NOR1 fusion appears to play an oncogenic role equivalent to those of other NOR1 fusions in EMC... - Sclerosing mucoepidermoid carcinoma with eosinophilia of the salivary gland: case report and review of the literatureTakashi Tasaki
Department of Pathology and Cell Biology, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 63:125-31. 2013..Only 23 cases of sclerosing mucoepidermoid carcinoma with or without eosinophilic infiltratie have been reported to date in such an anatomical location... - A case of intraosseous arteriovenous malformation with unusual radiological presentation of low blood flowAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu, Japan
Pathol Res Pract 204:423-6. 2008..Curettage of the lesion was carried out, and the histological diagnosis of AVM was made. In the context of this patient's lesion, it should be noted that AVM rarely presents as an intraosseous lesion with low blood flow... - Sclerosing variant of epithelioid angiomyolipomaAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 58:306-10. 2008..The characteristic clinicopathological and immunohistochemical features of the present cases are analogous to a subset of epithelioid AML or sclerosing perivascular epithelioid cell tumors previously reported... - TLE1 expression in malignant mesotheliomaAtsuji Matsuyama
Department of Pathology and Oncology, University of Occupational and Environmental Health, Yahatanishi ku, Kitakyushu, Japan
Virchows Arch 457:577-83. 2010..Our study showed no or limited value of the immunohistochemical TLE1 expression in distinguishing malignant mesothelioma and synovial sarcoma... - Aberrant PLAG1 expression in pleomorphic adenomas of the salivary gland: a molecular genetic and immunohistochemical studyAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu, Japan
Virchows Arch 458:583-92. 2011..The present results also suggest that overexpression of PLAG1 is essential for the tumorigenesis of pleomorphic adenomas, although the mechanisms mediating PLAG1 overexpression seem to be variable... - Spinal epithelioid hemangioendothelioma with epithelioid angiosarcomatous areasMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan
Skeletal Radiol 34:745-9. 2005..This phenomenon has been exceptionally described in cases with skeletal lesions, which are typically of low-grade malignancy... - PLAG1 expression in cutaneous mixed tumors: an immunohistochemical and molecular genetic studyAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
Virchows Arch 459:539-45. 2011..However, the mechanism of PLAG1 expression in cutaneous mixed tumors appears to be possibly different from that of pleomorphic adenomas... - Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcomaMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Lab Invest 82:1427-35. 2002..Our data suggest that the molecular alterations of the h-warts/LATS1 could be of pathologic importance in human sarcomagenesis... - Pulmonary hypoplasia on preterm infant associated with diffuse chorioamniotic hemosiderosis caused by intrauterine hemorrhage due to massive subchorial hematoma: report of a neonatal autopsy caseSohsuke Yamada
Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Fukuoka, Japan
Pathol Int 62:543-8. 2012..006 (less 0.012) of lung:body weight ratio. Since Breus' mole has a close relationship with intrauterine hemorrhage, resulting in DCH, IUGR, and/or pulmonary hypoplasia of the newborn, the present features might be typical... - Extraskeletal myxoid chondrosarcoma arising in the fingerSumika Okamoto
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan
Skeletal Radiol 31:296-300. 2002..Molecular detection of the tumor specific fusion gene could be a valuable aid for the final diagnosis of EMCS, particularly in cases with unusual clinicopathological features... 
Total anomalous pulmonary vein drainage: report of an autopsy case associated with atresia of the common pulmonary vein and left superior pulmonary veinSohsuke Yamada
Departments of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Fukuoka Shin Mizumaki Hospital, Kitakyushu, Japan
Pathol Int 61:93-8. 2011..To the authors' knowledge, this is the first case of TAPVD associated with ACPV, atresia of left superior pulmonary vein and pulmonary lymphangiectasis...- Angioleiomyoma: a clinicopathologic and immunohistochemical reappraisal with special reference to the correlation with myopericytomaAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Hum Pathol 38:645-51. 2007..The concentric structures of myoid cells in angioleiomyomas were, however, consistently negative for desmin. Our data further support the close kinship between angioleiomyoma and myopericytoma that has been recently suggested... - Adenocarcinomas with predominant ground-glass opacity: correlation of morphology and molecular biomarkersTakatoshi Aoki
Department of Radiology, University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan
Radiology 264:590-6. 2012..To retrospectively identify successive changes in peripheral lung adenocarcinoma that feature dominant ground-glass opacity (GGO) at computed tomography (CT) and correlate with biomolecular markers... - Extraspinal ependymoma of the broad ligamentAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
Pathol Int 60:241-4. 2010..The identification of characteristic histological features such as perivascular pseudorosettes and immunohistochemical expression of GFAP are helpful for confirming the diagnosis... - Vascular leiomyosarcoma: Clinicopathology and immunohistochemistry with special reference to a unique smooth muscle phenotypeAtsuji Matsuyama
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 60:212-6. 2010..These findings suggest that the vascular LMS displays a distinctive phenotype of smooth muscle differentiation according to histopathogenesis... - Gene expression of TrkC (NTRK3) in human soft tissue tumoursMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health UOEH, Kitakyushu, Japan
J Pathol 197:661-7. 2002..Dysregulated TrkC expression may enhance overgrowth or transformation of various mesenchymal cells... - Intranasal pericytic tumors (glomus tumor and sinonasal hemangiopericytoma-like tumor): report of two cases with review of the literatureXiao-Qiu Li
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 53:303-8. 2003.... - HMGIC alterations in smooth muscle tumors of soft tissues and other sitesMasanori Hisaoka
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu, 807 8555, Japan
Cancer Genet Cytogenet 138:50-5. 2002..Thus, the HMGIC alterations in smooth muscle tumors are not confined only to uterine leiomyoma or lipoleiomyoma. Our data expand the variety of mesenchymal tumors associated with HMGIC alterations... - Angiosarcoma of the scalp treated with curative radiotherapy plus recombinant interleukin-2 immunotherapyTakayuki Ohguri
Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Japan
Int J Radiat Oncol Biol Phys 61:1446-53. 2005..Recently, the effectiveness of immunotherapy with rIL-2 has also been reported in the treatment of angiosarcoma of the scalp... - Differential diagnosis of benign peripheral lipoma from well-differentiated liposarcoma on MR imaging: is comparison of margins and internal characteristics useful?Takayuki Ohguri
Department of Radiology, University of Occupational and Environmental Health, Iseigaoka 1 1, Yahatanisi ku, Kitakyushu shi 807 8555, Japan
AJR Am J Roentgenol 180:1689-94. 2003..Our objective was to evaluate the reliability of MR imaging in distinguishing between benign lipoma and well-differentiated liposarcoma... - Malignant diffuse-type tenosynovial giant cell tumor of the buttockReiichiro Kondo
Department of Pathology, Kurume University School of Medicine, Japan
Pathol Int 62:559-64. 2012..Pulmonary metastases were found 6 months after the operation. These findings indicate that this lesion is consistent with malignant D-TSGCT... - Synchronous sporadic gastrointestinal stromal tumors in the stomach and jejunum: report of a caseYoshifumi Nakayama
Department of Surgery 1, University of Occupational and Environmental Health, Kitakyushu, Japan Department of Gastroenterological and General Surgery, Wakamatsu Hospital of University of Occupational and Environmental Health, Kitakyushu, Japan
Case Rep Gastroenterol 7:69-74. 2013..Therefore, the final diagnosis was synchronous sporadic GISTs in the stomach and jejunum. This patient has survived without recurrence for approximately 12 years since complete resection... - DNA copy number changes in carcinoma in pleomorphic adenoma of the salivary gland: a comparative genomic hybridization studyTakashi Morio
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Pathol Int 52:501-7. 2002..Our data suggest that an accumulated or increased number of chromosomal changes including 6q abnormalities may be associated with the development of carcinomatous components in a subset of CPA... - Oncocytic schneiderian papilloma confined to the sphenoid sinus detected by FDG-PETTsuyoshi Udaka
Department of Otorhinolaryngology, University of Occupational and Environmental Health, Kitakyushu, Japan
Rhinology 45:89-92. 2007..FDG-PET is thought to be a powerful tool to search for malignant lesions, but the present case demonstrates the fallibility of this technique. This should be taken into consideration when interpreting FDG-PET images... - Congenital pulmonary lymphangiectasis: report of an autopsy case masquerading as pulmonary interstitial emphysemaSohsuke Yamada
Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu 807 8555, Japan
Pathol Res Pract 206:522-6. 2010.... - Juxta-articular myxoma and intramuscular myxoma are two distinct entities. Activating Gs alpha mutation at Arg 201 codon does not occur in juxta-articular myxomaSumika Okamoto
Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
Virchows Arch 440:12-5. 2002..We conclude that juxta-articular myxomas, in contrast to intramuscular myxomas, do not involve Arg 201 mutations of the Gs alpha gene, indicating that they represent distinct entities with different underlying molecular mechanisms... - Intestinal bleeding from arteriovenous malformations of the small bowel in a patient with Cowden syndrome: report of a caseYoshifumi Nakayama
Department of Surgery, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahata nishi ku, Kita Kyushu, 807 8555, Japan
Surg Today 43:542-6. 2013..This was a rare case of two AVMs involving the small bowel in a patient with Cowden syndrome. Enhanced CT was very useful and convenient for the detection of gastrointestinal AVMs in this case... - Coexistence of pyriform sinus fistula, ectopic lingual thyroid, and ectopic cervical thymusToyoaki Ohbuchi
Department of Otorhinolaryngology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Kitakyushu, Japan
Auris Nasus Larynx 39:634-7. 2012..We report an extremely rare case of coexistence of pyriform sinus fistula, ectopic lingual thyroid, and ectopic cervical thymus... - Giant cell carcinoma of the uterine cervix: a case reportTomoko Kurita
Department of Obstetrics and Gynecology, Kyushu Rosai Hospital, Kuzuhara-Takamatsu, Kokuraminamiku, Kitakyusyu, Japan
Int J Gynecol Pathol 25:298-300. 2006 - Extrauterine endometrial stromal sarcoma with JAZF1/JJAZ1 fusion confirmed by RT-PCR and interphase FISH presenting as an inguinal tumorKatsuaki Sato
Department of Pathophysiological and Experimental Pathology, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Kahoku, Ishikawa, 920 0293, Japan
Virchows Arch 450:349-53. 2007.... - A case of tenosynovial chondromatosis with tophus-like depositsTetsuya Ueo
Department of Pathology, Faculty of Medicine, Oita University, Oita, Japan
APMIS 112:624-8. 2004..Crystalline deposits in chondromas of soft tissue have been reported but not in tenosynovial chondromatosis... - Metastatic breast tumor arising from synovial sarcoma: report of a caseYuko Kijima
Department of Surgical Oncology, Breast and Endocrine Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8520, Japan
Surg Today 37:230-3. 2007..After the operation, the patient received adjuvant systemic chemotherapy. To the best of our knowledge, this is only the second reported case of a solitary metastatic breast tumor arising from synovial sarcoma... - Characteristic sequence motifs located at the genomic breakpoints of the translocation t(12;16) and t(12;22) in myxoid liposarcomaHua Xiang
Department of Pathology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou
Pathology 40:547-52. 2008..To analyse the characteristic sequence motifs around genomic breakpoints of translocations, t(12;16) and t(12;22), and to study the mechanisms underlying these chromosomal translocations in myxoid liposarcomas (MLS)...