R Hanajima

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. pmc Modulation of error-sensitivity during a prism adaptation task in people with cerebellar degeneration
    Ritsuko Hanajima
    Department of Neurology, University of Tokyo Hospital, Tokyo, Japan Department of Neurology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    J Neurophysiol 114:2460-71. 2015
  2. doi request reprint Triad-conditioning transcranial magnetic stimulation in Parkinson's disease
    Ritsuko Hanajima
    Department of Neurology, University of Tokyo Hospital, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan Electronic address
    Brain Stimul 7:74-9. 2014
  3. doi request reprint Short-interval intracortical inhibition in Parkinson's disease using anterior-posterior directed currents
    R Hanajima
    Department of Neurology, The University of Tokyo Hospital, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Exp Brain Res 214:317-21. 2011
  4. doi request reprint Triad stimulation frequency for cortical facilitation in cortical myoclonus
    R Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Mov Disord 26:685-90. 2011
  5. doi request reprint Postural tremor in X-linked spinal and bulbar muscular atrophy
    Ritsuko Hanajima
    Department of Neurology, The University of Tokyo Hospital, Tokyo, Japan
    Mov Disord 24:2063-9. 2009
  6. doi request reprint Forty-hertz triple-pulse stimulation induces motor cortical facilitation in humans
    Ritsuko Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Brain Res 1296:15-23. 2009
  7. doi request reprint Difference in intracortical inhibition of the motor cortex between cortical myoclonus and focal hand dystonia
    R Hanajima
    Department of Neurology, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 119:1400-7. 2008
  8. ncbi request reprint Intracortical inhibition of the motor cortex in Segawa disease (DYT5)
    R Hanajima
    Department of Neurology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Neurology 68:1039-44. 2007
  9. ncbi request reprint Intraoperative recording of the very fast oscillatory activities evoked by median nerve stimulation in the human thalamus
    R Hanajima
    Toronto Western Research Institute, University Health Network, Toronto, Canada
    Suppl Clin Neurophysiol 59:121-6. 2006
  10. ncbi request reprint Dissociation of thalamic high frequency oscillations and slow component of sensory evoked potentials following damage to ascending pathways
    Ritsuko Hanajima
    Toronto Western Research Institute, University Health Network, University of Toronto, Toronto, ONT Canada
    Clin Neurophysiol 117:906-11. 2006

Detail Information

Publications62

  1. pmc Modulation of error-sensitivity during a prism adaptation task in people with cerebellar degeneration
    Ritsuko Hanajima
    Department of Neurology, University of Tokyo Hospital, Tokyo, Japan Department of Neurology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
    J Neurophysiol 114:2460-71. 2015
    ..This improvement coincided with increased error-sensitivity and was present in both groups of subjects, suggesting that control of error-sensitivity may be spared despite cerebellar damage. ..
  2. doi request reprint Triad-conditioning transcranial magnetic stimulation in Parkinson's disease
    Ritsuko Hanajima
    Department of Neurology, University of Tokyo Hospital, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan Electronic address
    Brain Stimul 7:74-9. 2014
    ..We recently reported a new method of triad-conditioning TMS to detect the excitability changes after rhythmic conditioning stimuli, which induce facilitation by 40-Hz stimulation in healthy volunteers...
  3. doi request reprint Short-interval intracortical inhibition in Parkinson's disease using anterior-posterior directed currents
    R Hanajima
    Department of Neurology, The University of Tokyo Hospital, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Exp Brain Res 214:317-21. 2011
    ..This discrepancy between SICI using posterior-anterior and anterior-posterior directed currents experiments may provide additional information about the circuits of the motor cortex...
  4. doi request reprint Triad stimulation frequency for cortical facilitation in cortical myoclonus
    R Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Bunkyo ku, Tokyo, Japan
    Mov Disord 26:685-90. 2011
    ..In this investigation, we study the motor cortical facilitation induced by rhythmic triple TMS pulses (triad-conditioning TMS) in patients with cortical myoclonus...
  5. doi request reprint Postural tremor in X-linked spinal and bulbar muscular atrophy
    Ritsuko Hanajima
    Department of Neurology, The University of Tokyo Hospital, Tokyo, Japan
    Mov Disord 24:2063-9. 2009
    ..Subclinical sensory disturbance or a decrease of motor unit numbers might be candidates for such peripheral factors contributing to tremor genesis in SBMA...
  6. doi request reprint Forty-hertz triple-pulse stimulation induces motor cortical facilitation in humans
    Ritsuko Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Brain Res 1296:15-23. 2009
    ..These results suggest that a triad of TMS pulses can enhance an intrinsic oscillatory rhythm of the motor cortex (40 Hz) and facilitate cortical activity at an ISI corresponding to the frequency of that rhythm...
  7. doi request reprint Difference in intracortical inhibition of the motor cortex between cortical myoclonus and focal hand dystonia
    R Hanajima
    Department of Neurology, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 119:1400-7. 2008
    ..The aim of this study was to elucidate possible differences in intracortical inhibition between these two disorders...
  8. ncbi request reprint Intracortical inhibition of the motor cortex in Segawa disease (DYT5)
    R Hanajima
    Department of Neurology, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Neurology 68:1039-44. 2007
    ..Segawa disease (autosomal dominant guanosine triphosphate cyclohydrolase I [GTP-I] deficiency, DYT5) is a hereditary dopa-responsive generalized dystonia...
  9. ncbi request reprint Intraoperative recording of the very fast oscillatory activities evoked by median nerve stimulation in the human thalamus
    R Hanajima
    Toronto Western Research Institute, University Health Network, Toronto, Canada
    Suppl Clin Neurophysiol 59:121-6. 2006
  10. ncbi request reprint Dissociation of thalamic high frequency oscillations and slow component of sensory evoked potentials following damage to ascending pathways
    Ritsuko Hanajima
    Toronto Western Research Institute, University Health Network, University of Toronto, Toronto, ONT Canada
    Clin Neurophysiol 117:906-11. 2006
    ..In this study, we examined how lesions in the sensory afferent pathway affect these components...
  11. ncbi request reprint Very fast oscillations evoked by median nerve stimulation in the human thalamus and subthalamic nucleus
    Ritsuko Hanajima
    Toronto Western Research Institute, University Health Network, University of Toronto, Ontario, Canada
    J Neurophysiol 92:3171-82. 2004
    ..The VFOs from STN probably represent volume conduction, possibly from the medial lemniscus. We conclude that the thalamic VFOs are generated within Vc and that they induce time-locked firing in a network of neurons...
  12. ncbi request reprint Single pulse stimulation of the human subthalamic nucleus facilitates the motor cortex at short intervals
    Ritsuko Hanajima
    Dept of Neurology, University of Tokyo Hospital, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Neurophysiol 92:1937-43. 2004
    ..Single pulse STN stimulation facilitates the M1 at short latencies. The possible mechanisms include antidromic excitation of the cortico-STN fibers or transmission through the basal ganglia-thalamocortical pathway...
  13. ncbi request reprint A single motor unit recording technique for studying the differential activation of corticospinal volleys by transcranial magnetic stimulation
    Y Terao
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
    Brain Res Brain Res Protoc 7:61-7. 2001
    ..The obtained results accord well with recent epidural recording studies, which lends support to the validity of this method...
  14. ncbi request reprint Interhemispheric interaction between the hand motor areas in patients with cortical myoclonus
    R Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Clin Neurophysiol 112:623-6. 2001
    ..We propose that this releases interhemispheric facilitation from powerful surround inhibition. The consequence is a predominant early facilitation between the hemispheres in patients with myoclonus epilepsy...
  15. pmc Interhemispheric facilitation of the hand motor area in humans
    R Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Physiol 531:849-59. 2001
    ..The stronger the conditioning stimulus was, the greater was the amount of inhibition. These results are compatible with surround inhibition at the motor cortex...
  16. ncbi request reprint Hemispheric lateralization in the cortical motor preparation for human vocalization
    Y Terao
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    J Neurosci 21:1600-9. 2001
    ..Our results also suggested involvement of the motor representation of respiratory muscles and also of supplementary motor cortex...
  17. doi request reprint Effects of STN stimulation on the initiation and inhibition of saccade in Parkinson disease
    A Yugeta
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neurology 74:743-8. 2010
    ..Nevertheless, the effects of STN DBS on saccade performance are not fully clarified in a systematic manner. In this study, we examined the effects of bilateral STN DBS on both the initiation and inhibition of saccades in PD...
  18. ncbi request reprint Somatosensory evoked potential recovery in myotonic dystrophy
    H Mochizuki
    Department of Neurology, National Shimoshizu Hospital, Shikawatashi 934-5, Yotsukaido, 284-0003, Chiba, Japan
    Clin Neurophysiol 112:793-9. 2001
    ..CONCLUSIONS: Disinhibited cortical excitability (or hyperexcitability) is present in the sensory cortex in patients with myotonic dystrophy. This may reflect cortical pathology or functional alteration of the sensory cortex in MD...
  19. ncbi request reprint Decreased sensory cortical excitability after 1 Hz rTMS over the ipsilateral primary motor cortex
    H Enomoto
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan
    Clin Neurophysiol 112:2154-8. 2001
    ..1 times the active motor threshold, probably via cortico-cortical pathways between motor and sensory cortex...
  20. ncbi request reprint Hemoglobin concentration changes in the contralateral hemisphere during and after theta burst stimulation of the human sensorimotor cortices
    Hitoshi Mochizuki
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Exp Brain Res 180:667-75. 2007
    ..Those are partly compatible with the previous findings. In addition to between the primary motor cortices, bilateral connection is requisite for smooth bimanual coordination between the sensory cortices or premotor cortices...
  21. doi request reprint Double-pulse magnetic brain stem stimulation: mimicking successive descending volleys
    Hideyuki Matsumoto
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Neurophysiol 100:3437-44. 2008
    ..Using this new technique, we can obtain more information about the central motor conduction even when single BST fails to elicit any MEP...
  22. ncbi request reprint Effects of thirty minutes mobile phone use on the human sensory cortex
    Kaoru Yuasa
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 117:900-5. 2006
    ..To investigate whether the pulsed high-frequency electromagnetic field (pulsed EMF) emitted by a mobile phone for 30 min has short-term effects on human somatosensory evoked potentials (SEPs)...
  23. ncbi request reprint Median nerve somatosensory evoked potentials and their high-frequency oscillations in amyotrophic lateral sclerosis
    Masashi Hamada
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 118:877-86. 2007
    ..To investigate sensory cortical changes in amyotrophic lateral sclerosis (ALS), we studied somatosensory evoked potentials (SEPs) and their high-frequency oscillation potentials...
  24. doi request reprint Cortico-conus motor conduction time (CCCT) for leg muscles
    Hideyuki Matsumoto
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, Japan
    Clin Neurophysiol 121:1930-3. 2010
    ..To measure the conduction time from the motor cortex to the conus medullaris (cortico-conus motor conduction time, CCCT) for leg muscles using magnetic stimulation...
  25. doi request reprint Magnetic stimulation of the cauda equina in the spinal canal with a flat, large round coil
    Hideyuki Matsumoto
    Department of Neurology, Division of Neuroscience Graduate School of Medicine, University of Tokyo, Japan
    J Neurol Sci 284:46-51. 2009
    ..The MATS coil facilitates evaluation of spinal nerve conduction in the cauda equina...
  26. doi request reprint Magnetic lumbosacral motor root stimulation with a flat, large round coil
    Hideyuki Matsumoto
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 120:770-5. 2009
    ..The aim of this paper is to develop a reliable method for supramaximal magnetic spinal motor root stimulation (MRS) for lower limb muscles using a specially devised coil...
  27. ncbi request reprint Short and long duration transcranial direct current stimulation (tDCS) over the human hand motor area
    Toshiaki Furubayashi
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Tokyo 113 8655, Japan
    Exp Brain Res 185:279-86. 2008
    ..The effect provoked by long duration tDCS may be short-term potentiation or depression like effects...
  28. ncbi request reprint Somatosensory evoked potentials (SEPs) recorded from deep brain stimulation (DBS) electrodes in the thalamus and subthalamic nucleus (STN)
    Ritsuko Hanajima
    Toronto Western Research Institute, Toronto Western Hospital, 399 Bathurst St, Toronto, ON M5T 2S8, Canada
    Clin Neurophysiol 115:424-34. 2004
    ..To examine the location of deep brain stimulation (DBS) electrode somatosensory evoked potentials (SEPs) and determine the generators of the median nerve SEPs recorded in thalamus and subthalamic nucleus (STN)...
  29. ncbi request reprint Quadro-pulse stimulation is more effective than paired-pulse stimulation for plasticity induction of the human motor cortex
    Masashi Hamada
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Neurophysiol 118:2672-82. 2007
    ..We hypothesized that a greater enhancement of motor cortical excitability is provoked by increasing the number of pulses per train beyond those by paired-pulse stimulation (PPS)...
  30. doi request reprint Influence of short-interval intracortical inhibition on short-interval intracortical facilitation in human primary motor cortex
    Yuichiro Shirota
    Dept of Neurology, Div of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Neurophysiol 104:1382-91. 2010
    ..We propose that CS might inhibit the second peak of SICF at the interneurons responsible for I3 waves...
  31. pmc Bidirectional long-term motor cortical plasticity and metaplasticity induced by quadripulse transcranial magnetic stimulation
    Masashi Hamada
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Physiol 586:3927-47. 2008
    ..The broad range of after-effects produced by the new rTMS protocol opens up new possibilities for detailed examination of theories of metaplasticity in humans...
  32. doi request reprint Motor cortical epilepsia partialis continua in a patient with a localized sensory cortical lesion
    Setsu Nakatani-Enomoto
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Clin Neurol Neurosurg 111:762-5. 2009
    ..The brain MRI showed a high intensity lesion localized at the hand sensory area. These results suggest that the jerks were produced by discharges at the motor cortex probably disinhibited by the sensory cortical lesion...
  33. ncbi request reprint Remote effects of self-paced teeth clenching on the excitability of hand motor area
    Toshiaki Furubayashi
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Exp Brain Res 148:261-5. 2003
    ....
  34. ncbi request reprint Neurophysiology of cortical positive myoclonus
    Yoshikazu Ugawa
    Department of Neurology, Division of Neuroscience, University of Tokyo, Tokyo, Japan
    Adv Neurol 89:89-97. 2002
  35. doi request reprint Efferent and afferent evoked potentials in patients with adrenomyeloneuropathy
    Hideyuki Matsumoto
    Department of Neurology, University of Tokyo, Japan
    Clin Neurol Neurosurg 112:131-6. 2010
    ..This paper investigates efferent and afferent conductions of the central nervous system by various evoked potentials in patients with adrenomyeloneuropathy (AMN)...
  36. ncbi request reprint Characteristics and distribution of somatosensory evoked potentials in the subthalamic region
    Mayumi Kitagawa
    Department of Neurology, Sapporo Azabu Neurosurgical Hospital, Sapporo, Japan
    J Neurosurg 107:548-54. 2007
    ..Determination of this distribution may help in the correct placement of deep brain stimulation (DBS) leads...
  37. doi request reprint Cerebellar dysfunction in progressive supranuclear palsy: a transcranial magnetic stimulation study
    Yuichiro Shirota
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Mov Disord 25:2413-9. 2010
    ..Our results are compatible with the pathological findings showing severe dentate nucleus degeneration in PSP patients...
  38. ncbi request reprint Origin of facilitation in repetitive, 1.5ms interval, paired pulse transcranial magnetic stimulation (rPPS) of the human motor cortex
    Masashi Hamada
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1, Hongo, Tokyo, Japan
    Clin Neurophysiol 118:1596-601. 2007
    ..To confirm its cortical facilitation, we compared the after-effects of rPPS on MEPs to single pulse TMS over the motor cortex (motor cortical MEPs) with those to brainstem stimulation (brainstem MEPs)...
  39. pmc Mechanisms of intracortical I-wave facilitation elicited with paired-pulse magnetic stimulation in humans
    Ritsuko Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Japan
    J Physiol 538:253-61. 2002
    ....
  40. ncbi request reprint Exaggerated 16-20 Hz motor cortical oscillation in patients with positive or negative myoclonus
    Yoshikazu Ugawa
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 114:1278-84. 2003
    ..In the present paper, we describe 4 patients with non-repetitive positive or negative myoclonus whose jerks were preceded by 16-20 Hz oscillatory EEG potentials over the contralateral sensorimotor cortex...
  41. ncbi request reprint Vocal amusia in a professional tango singer due to a right superior temporal cortex infarction
    Yasuo Terao
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neuropsychologia 44:479-88. 2006
    ..Such impairment could not be explained by the impairment of pitch perception. The findings suggest that damage to the right temporoparietal cortex is enough to produce both perceptive and expressive deficits in music...
  42. ncbi request reprint Effect of low-frequency repetitive transcranial magnetic stimulation on interhemispheric inhibition
    Pramod Kr Pal
    Divsion of Neurology and Krembil Neuroscience Centre, Toronto Western Research Institute, University Health Network, University of Toronto, Ontario, Canada
    J Neurophysiol 94:1668-75. 2005
    ..Treatment protocols using low-frequency rTMS to reduce cortical excitability in neurological and psychiatric conditions need to take into account their effects on IHI...
  43. ncbi request reprint Periodic motor cortical excitability changes associated with PSDs of EEG in Creutzfeldt-Jakob disease (CJD)
    Kaori Sakuishi
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, Japan
    Clin Neurophysiol 116:1222-6. 2005
    ..To assess the temporal relationship between excitability changes of the motor cortex and periodic synchronous discharges (PSDs) of electroencephalograms (EEGs) in Creutzfeld-Jakob disease (CJD) patients...
  44. ncbi request reprint Facilitatory effect on the motor cortex by electrical stimulation over the cerebellum in humans
    Nobue Kobayashi Iwata
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, 113 8655, Tokyo, Japan
    Exp Brain Res 159:418-24. 2004
    ..We conclude that the motor cortical facilitation is evoked by cerebellar stimulation in humans...
  45. ncbi request reprint Recovery function of and effects of hyperventilation on somatosensory evoked high-frequency oscillation in Parkinson's disease and myoclonus epilepsy
    Hitoshi Mochizuki
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neurosci Res 46:485-92. 2003
    ..We conclude that (1) Giant HFOs are normally regulated by inhibitory neuronal systems involving in paired stimulation SEP. (2) The late HFOs must reflect bursts of GABAergic inhibitory interneurons...
  46. ncbi request reprint Effects of motor cortical stimulation on the excitability of contralateral motor and sensory cortices
    Hitoshi Mochizuki
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo Bunkyo ku, 113 8655 Tokyo, Japan
    Exp Brain Res 158:519-26. 2004
    ..This has a secondary effect of enhancing the responsiveness of the sensory cortex through cortico-cortical connections...
  47. ncbi request reprint Differences in after-effect between monophasic and biphasic high-frequency rTMS of the human motor cortex
    Noritoshi Arai
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 118:2227-33. 2007
    ..To study differences in the long-term after-effect between high-frequency, monophasic and biphasic repetitive transcranial magnetic stimulation (rTMS)...
  48. doi request reprint Supramaximal responses can be elicited in hand muscles by magnetic stimulation of the cervical motor roots
    Lumine Matsumoto
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Brain Stimul 3:153-60. 2010
    ..The amplitude of compound muscle action potentials (CMAPs) evoked in response to magnetic cervical motor root stimulation (MRS) has rarely been used as a diagnostic parameter because of the difficulty in obtaining supramaximal CMAPs...
  49. pmc Primary motor cortical metaplasticity induced by priming over the supplementary motor area
    Masashi Hamada
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, 7 3 1, Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Physiol 587:4845-62. 2009
    ..The data support the view that the homeostatic changes are mediated via mechanisms of metaplasticity and highlight an important interplay between M1 and SMA regarding homeostatic plasticity in humans...
  50. ncbi request reprint Unique form of propriospinal myoclonus as a possible complication of an enteropathogenic toxin
    Alberto J Espay
    Department of Medicine, Division of Neurology, The Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    Mov Disord 18:942-8. 2003
    ..A toxin-mediated microvascular thrombosis is proposed as a possible pathogenic mechanism underlying this novel association...
  51. doi request reprint The effect of electromagnetic field emitted by a mobile phone on the inhibitory control of saccades
    Tomoko Okano
    Department of Laboratory Medicine, Graduate School of Medicine, University of Tokyo, Japan
    Clin Neurophysiol 121:603-11. 2010
    ..To investigate whether exposure to a pulsed high-frequency electromagnetic field (pulsed EMF) emitted by a mobile phone has short-term effects on the inhibitory control of saccades...
  52. doi request reprint Prominent cauda equina involvement in patients with chronic inflammatory demyelinating polyradiculoneuropathy
    Hideyuki Matsumoto
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan
    J Neurol Sci 290:112-4. 2010
    ..CECT was prolonged in 9 patients (81.8%), whereas the ankle-knee conduction was delayed in 4 (36.4%). The proximal segments are more frequently involved than the distal segments in this disorder...
  53. ncbi request reprint Task-guided selection of the dual neural pathways for reading
    Kimihiro Nakamura
    Department of Speech Physiology, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Neuron 52:557-64. 2006
    ....
  54. ncbi request reprint Further evidence to support different mechanisms underlying intracortical inhibition of the motor cortex
    Ritsuko Hanajima
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Exp Brain Res 151:427-34. 2003
    ....
  55. doi request reprint Clinical efficacy of istradefylline (KW-6002) in Parkinson's disease: a randomized, controlled study
    Yoshikuni Mizuno
    Department of Neurology, Research Institute for Diseases of Old Age, Juntendo University School of Medicine, Tokyo, Japan
    Mov Disord 25:1437-43. 2010
    ..4% (8/125) receiving 40 mg/day istradefylline. We conclude that istradefylline at 20 mg and 40 mg once daily is effective in relieving wearing-off fluctuations of PD patients. In addition, istradefylline was well tolerated at both doses...
  56. doi request reprint Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial
    Masahisa Katsuno
    Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Lancet Neurol 9:875-84. 2010
    ..We aimed to assess the efficacy and safety of leuprorelin for spinal and bulbar muscular atrophy...
  57. ncbi request reprint Lambert-Eaton myasthenic syndrome associated with idiopathic thrombocytopenic purpura and diffuse panbronchiolitis: long-term remission after a course of intravenous immunoglobulin combined with low-dose prednisolone
    T Takata
    Department of Neurology, Graduate School of Medicine, University of Tokyo, Japan
    Am J Med Sci 318:353-5. 1999
    ..4 g/kg/day x 5 days), low-dose PSL (20 mg/day) alleviated the LEMS and ITP, and the diseases have remained in remission for 8 months without additional IVIG. We suspect that there is a synergistic relationship between IVIG and PSL...
  58. ncbi request reprint Acute effect of transcutaneous electrical nerve stimulation on tremor
    Renato P Munhoz
    Movement Disorders Centre, Toronto Western Hospital, University of Toronto, Toronto, Canada
    Mov Disord 18:191-4. 2003
    ..We found no significant improvement in any of the parameters tested...
  59. ncbi request reprint Effects of high frequency electromagnetic field (EMF) emitted by mobile phones on the human motor cortex
    Satomi Inomata-Terada
    Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Bioelectromagnetics 28:553-61. 2007
    ..This is the first study of MEPs after electromagnetic exposure from a mobile phone in neurological patients...
  60. ncbi request reprint Functional connectivity revealed by single-photon emission computed tomography (SPECT) during repetitive transcranial magnetic stimulation (rTMS) of the motor cortex
    Shingo Okabe
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Clin Neurophysiol 114:450-7. 2003
    ..In the present study, we studied effects of 1 Hz repetitive transcranial magnetic stimulation (rTMS) over the left primary motor cortex (M1) on regional cerebral blood flow (rCBF) using single-photon emission computed tomography (SPECT)...
  61. doi request reprint Effects of a high-frequency, low-intensity, biphasic conditioning train of TMS pulses on the human motor cortex
    Noritoshi Arai
    Department of Neurology, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Neurosci Lett 462:188-92. 2009
    ..Furthermore, CS10 evoked MEP inhibition at longer intervals. Results show that a train of high-frequency, low-intensity, biphasic TMS pulses can have a strong inhibitory effect on the motor cortex...
  62. ncbi request reprint Comparison of different methods for estimating motor threshold with transcranial magnetic stimulation
    Ritsuko Hanajima
    Clin Neurophysiol 118:2120-2. 2007