Kei Hamazaki

Summary

Affiliation: University of Toyama
Country: Japan

Publications

  1. pmc Tachikawa project for prevention of posttraumatic stress disorder with polyunsaturated fatty acid (TPOP): study protocol for a randomized controlled trial
    Yutaka Matsuoka
    Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, 190 0014, Tachikawa, Tokyo, Japan
    BMC Psychiatry 13:8. 2013
  2. doi request reprint Fatty acid composition in the postmortem amygdala of patients with schizophrenia, bipolar disorder, and major depressive disorder
    Kei Hamazaki
    Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama, Japan
    J Psychiatr Res 46:1024-8. 2012
  3. pmc Concern over radiation exposure and psychological distress among rescue workers following the Great East Japan Earthquake
    Yutaka Matsuoka
    Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, Tachikawa 190 0014, Japan
    BMC Public Health 12:249. 2012
  4. pmc Attenuating posttraumatic distress with omega-3 polyunsaturated fatty acids among disaster medical assistance team members after the Great East Japan Earthquake: the APOP randomized controlled trial
    Yutaka Matsuoka
    Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, Tachikawa 190 0014, Japan
    BMC Psychiatry 11:132. 2011
  5. ncbi request reprint The relationship between n-3 long-chain polyunsaturated fatty acids and pulse wave velocity in diabetic and non-diabetic patients under long-term hemodialysis. A horizontal study
    K Hamazaki
    Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan
    Clin Nephrol 71:508-13. 2009
  6. pmc Phospholipid profile in the postmortem hippocampus of patients with schizophrenia and bipolar disorder: no changes in docosahexaenoic acid species
    Kei Hamazaki
    Laboratory of Molecular Signaling, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N07, MSC9410, Bethesda, MD 20892 9410, USA
    J Psychiatr Res 44:688-93. 2010
  7. doi request reprint Docosahexaenoic acid is an independent predictor of all-cause mortality in hemodialysis patients
    Kei Hamazaki
    Department of Public Health, Faculty of Medicine, University of Toyama, Japan
    Am J Nephrol 33:105-10. 2011
  8. ncbi request reprint Effect of omega-3 fatty acid-containing phospholipids on blood catecholamine concentrations in healthy volunteers: a randomized, placebo-controlled, double-blind trial
    Kei Hamazaki
    Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Japan
    Nutrition 21:705-10. 2005
  9. ncbi request reprint Suicide attempt and n-3 fatty acid levels in red blood cells: a case control study in China
    Mingming Huan
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama City, Japan
    Biol Psychiatry 56:490-6. 2004
  10. ncbi request reprint The effects of eicosapentaenoic acid-fortified food on inflammatory markers in healthy subjects--A randomized, placebo-controlled, double-blind study
    Shuntaro Fujioka
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930 0194, Japan
    J Nutr Sci Vitaminol (Tokyo) 52:261-5. 2006

Collaborators

Detail Information

Publications25

  1. pmc Tachikawa project for prevention of posttraumatic stress disorder with polyunsaturated fatty acid (TPOP): study protocol for a randomized controlled trial
    Yutaka Matsuoka
    Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, 190 0014, Tachikawa, Tokyo, Japan
    BMC Psychiatry 13:8. 2013
    ..This paper describes the rationale and protocol of this trial...
  2. doi request reprint Fatty acid composition in the postmortem amygdala of patients with schizophrenia, bipolar disorder, and major depressive disorder
    Kei Hamazaki
    Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama, Japan
    J Psychiatr Res 46:1024-8. 2012
    ..0% decrease in docosatetraenoic acid compared to controls. In conclusion, the changes in DHA and/or AA seen in orbitofrontal cortex and hippocampus were not observed in amygdala. These changes may be specific to particular brain regions...
  3. pmc Concern over radiation exposure and psychological distress among rescue workers following the Great East Japan Earthquake
    Yutaka Matsuoka
    Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, Tachikawa 190 0014, Japan
    BMC Public Health 12:249. 2012
    ..Moreover, it is unclear to what extent concern over radiation exposure has caused psychological distress to such workers deployed in the disaster area...
  4. pmc Attenuating posttraumatic distress with omega-3 polyunsaturated fatty acids among disaster medical assistance team members after the Great East Japan Earthquake: the APOP randomized controlled trial
    Yutaka Matsuoka
    Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, Tachikawa 190 0014, Japan
    BMC Psychiatry 11:132. 2011
    ..So far we have shown in an open trial that posttraumatic stress disorder symptoms in critically injured patients can be reduced by taking omega-3 fatty acids intended to stimulate hippocampal neurogenesis...
  5. ncbi request reprint The relationship between n-3 long-chain polyunsaturated fatty acids and pulse wave velocity in diabetic and non-diabetic patients under long-term hemodialysis. A horizontal study
    K Hamazaki
    Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan
    Clin Nephrol 71:508-13. 2009
    ..However, it has not yet been reported whether n-3 LCPUFAs are related to arteriosclerosis in patients under long-term hemodialysis (HD)...
  6. pmc Phospholipid profile in the postmortem hippocampus of patients with schizophrenia and bipolar disorder: no changes in docosahexaenoic acid species
    Kei Hamazaki
    Laboratory of Molecular Signaling, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N07, MSC9410, Bethesda, MD 20892 9410, USA
    J Psychiatr Res 44:688-93. 2010
    ..The selective decrease in 22:5n-6 without affecting DHA contents suggests altered lipid metabolism, particularly n-6 PUFA rather than n-3 PUFA, in the hippocampus of individuals with schizophrenia or bipolar disorder...
  7. doi request reprint Docosahexaenoic acid is an independent predictor of all-cause mortality in hemodialysis patients
    Kei Hamazaki
    Department of Public Health, Faculty of Medicine, University of Toyama, Japan
    Am J Nephrol 33:105-10. 2011
    ..The aim of this study was to determine whether DHA levels in RBCs predict the mortality of patients on HD in a prospective cohort study...
  8. ncbi request reprint Effect of omega-3 fatty acid-containing phospholipids on blood catecholamine concentrations in healthy volunteers: a randomized, placebo-controlled, double-blind trial
    Kei Hamazaki
    Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Japan
    Nutrition 21:705-10. 2005
    ..Therefore, we performed another intervention study to test their effect on catecholamines with healthy subjects under no chronic stress...
  9. ncbi request reprint Suicide attempt and n-3 fatty acid levels in red blood cells: a case control study in China
    Mingming Huan
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama City, Japan
    Biol Psychiatry 56:490-6. 2004
    ..Epidemiologic studies show that low fish intake is a risk factor of suicidality; however, there are no case-control studies investigating suicide attempt risk and tissue n-3 fatty acid levels...
  10. ncbi request reprint The effects of eicosapentaenoic acid-fortified food on inflammatory markers in healthy subjects--A randomized, placebo-controlled, double-blind study
    Shuntaro Fujioka
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930 0194, Japan
    J Nutr Sci Vitaminol (Tokyo) 52:261-5. 2006
    ..68%). The inflammatory markers did not change in either group. It is likely that fish oil does not change hs-CRP or sTNF-Rs 1 or 2 in subjects without active inflammation...
  11. ncbi request reprint The effects of docosahexaenoic acid-rich fish oil on behavior, school attendance rate and malaria infection in school children--a double-blind, randomized, placebo-controlled trial in Lampung, Indonesia
    Kei Hamazaki
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 930 0194, Japan
    Asia Pac J Clin Nutr 17:258-63. 2008
    ..There are only a very limited number of reports of intervention studies on the effects of fish oil on behavior in normal school children...
  12. ncbi request reprint The relationship between tissue RBC n-3 fatty acids and pulse wave velocity
    Hiroto Nishizawa
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 9300194, Japan
    In Vivo 20:307-10. 2006
    ..Although baPWV values may not directly indicate arteriosclerosis, the present study suggests that long-term n-3 fatty acid intake is beneficial for the vascular system...
  13. ncbi request reprint Factors influencing EPA+DHA levels in red blood cells in Japan
    Miho Itomura
    Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930 0194, Japan
    In Vivo 22:131-5. 2008
    ..31), (ii) age (beta=0.33), (iii) gender (beta=-0.15) and (iv) physical activity (beta=-0.11) but not with body mass index or smoking...
  14. ncbi request reprint The effect of fish oil on physical aggression in schoolchildren--a randomized, double-blind, placebo-controlled trial
    Miho Itomura
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan 9300194
    J Nutr Biochem 16:163-71. 2005
    ..The aim of the study was to investigate whether fish oil supplementation affected Japanese schoolchildren's behavior, with changes in aggression over time as the primary endpoint...
  15. ncbi request reprint Fish oil reduces tooth loss mainly through its anti-inflammatory effects?
    Kei Hamazaki
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 930 0194, Japan
    Med Hypotheses 67:868-70. 2006
    ..This hypothesis may explain the linkage between periodontitis/tooth loss and coronary heart disease...
  16. ncbi request reprint The effect of n - 3 PUFA/gamma-cyclodextrin complex on serum lipids in healthy volunteers--a randomized, placebo-controlled, double-blind trial
    Koji Kobayashi
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 9300194, Japan
    Asia Pac J Clin Nutr 16:429-34. 2007
    ....
  17. ncbi request reprint Effects of cooking plant oils on recurrent aphthous stomatitis: a randomized, placebo-controlled, double-blind trial
    Kei Hamazaki
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama, Japan
    Nutrition 22:534-8. 2006
    ..However, well-controlled dietary intervention studies to prevent minor RAS are very rare. The objective of the present study was to investigate whether the prevalence of RAS decreased with perilla oil (rich in alpha-linolenic acid)...
  18. ncbi request reprint n-3 long-chain FA decrease serum levels of TG and remnant-like particle-cholesterol in humans
    Kei Hamazaki
    Department of Clinical Application, Institute of Natural Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama shi, Toyama 930 0194, Japan
    Lipids 38:353-8. 2003
    ..The groups did not differ in the other lipid levels. It is likely that n-3 long-chain FA may exert anti-atherosclerotic effects by lowering serum TG and RLP-cholesterol levels even at the dose of 860 mg/d...
  19. ncbi request reprint Relationships among skin conditions, mood, and polyunsaturated fatty acids of RBCs in healthy women
    Nina Hamazaki-Fujita
    Kracie Pharma, Ltd, Takaoka City, Toyama, Japan
    J Cosmet Sci 63:303-10. 2012
    ..Pigmentation characteristics in the forehead were independent from other areas of the face. Negative mood and AA were adversely correlated with skin conditions...
  20. doi request reprint Fish oils and aggression or hostility
    Tomohito Hamazaki
    Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2680 Sugitani, Toyama City, Toyama 9300194, Japan
    Prog Lipid Res 47:221-32. 2008
    ..Among them, activation of the serotonergic neuron system is the most promising. The research area of fish oils and aggression/hostility is clearly important from the medical and social points of view...
  21. ncbi request reprint The effect of eicosapentaenoic acid on prostate-specific antigen
    Kei Hamazaki
    Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama, Japan
    In Vivo 20:397-401. 2006
    ..5+/-14.0%). There were no significant differences between the two groups in the serum PSA levels, allowing the conclusion that the PSA is an appropriate surrogate marker of recurrence in prostate cancer...
  22. pmc A critical evaluation of influence of ethanol and diet on salsolinol enantiomers in humans and rats
    Jeongrim Lee
    Laboratory of Molecular Signaling, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA
    Alcohol Clin Exp Res 34:242-50. 2010
    ..Using a newly developed mass spectrometric method to analyze SAL stereoisomers, we evaluated the contribution of ethanol, diet, and genetic background to SAL levels as well as its enantiomeric distribution...
  23. pmc Differential modification of the phospholipid profile by transient ischemia in rat hippocampal CA1 and CA3 regions
    Kei Hamazaki
    Laboratory of Molecular Signaling, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N 07, Bethesda, MD 20892 9410, United States
    Prostaglandins Leukot Essent Fatty Acids 88:299-306. 2013
    ..Also, selective activation of phospholipase A2, which primarily releases polyunsaturated fatty acids, might not be characteristic to cell death in CA1...
  24. doi request reprint Molecular mechanisms involved in the adaptive response to cadmium-induced apoptosis in human myelomonocytic lymphoma U937 cells
    Zheng Guo Cui
    Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama 930 0194, Japan
    Toxicol In Vitro 25:1687-93. 2011
    ..The mechanism involves inhibition of intracellular ROS generation and JNK activation, and modulating the balance between the expression of Mcl-1 and its binding partners, Bim, Noxa and tBid...
  25. doi request reprint The depressive effects of 5,8,11-eicosatrienoic Acid (20:3n-9) on osteoblasts
    Tomohito Hamazaki
    Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama 9300194, Japan
    Lipids 44:97-102. 2009
    ..The presence of 20:3n-9 in fetal cartilage may be important for the prevention of calcification in the cartilage. 20:3n-9 could be applied to some clinical situations where bone formation should be inhibited...