Research Topics
| Kei HamazakiSummaryAffiliation: University of Toyama Country: Japan Publications
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Detail Information
Publications
Fatty acid composition in the postmortem amygdala of patients with schizophrenia, bipolar disorder, and major depressive disorderKei Hamazaki
Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama, Japan
J Psychiatr Res 46:1024-8. 2012..0% decrease in docosatetraenoic acid compared to controls. In conclusion, the changes in DHA and/or AA seen in orbitofrontal cortex and hippocampus were not observed in amygdala. These changes may be specific to particular brain regions...
Concern over radiation exposure and psychological distress among rescue workers following the Great East Japan EarthquakeYutaka Matsuoka
Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, Tachikawa 190 0014, Japan
BMC Public Health 12:249. 2012..Moreover, it is unclear to what extent concern over radiation exposure has caused psychological distress to such workers deployed in the disaster area...- Attenuating posttraumatic distress with omega-3 polyunsaturated fatty acids among disaster medical assistance team members after the Great East Japan Earthquake: the APOP randomized controlled trialYutaka Matsuoka
Department of Psychiatry, National Disaster Medical Center, 3256 Midoricho, Tachikawa 190 0014, Japan
BMC Psychiatry 11:132. 2011..So far we have shown in an open trial that posttraumatic stress disorder symptoms in critically injured patients can be reduced by taking omega-3 fatty acids intended to stimulate hippocampal neurogenesis... 
The relationship between n-3 long-chain polyunsaturated fatty acids and pulse wave velocity in diabetic and non-diabetic patients under long-term hemodialysis. A horizontal studyK Hamazaki
Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Faculty of Medicine, University of Toyama, Toyama, Japan
Clin Nephrol 71:508-13. 2009..However, it has not yet been reported whether n-3 LCPUFAs are related to arteriosclerosis in patients under long-term hemodialysis (HD)...- Phospholipid profile in the postmortem hippocampus of patients with schizophrenia and bipolar disorder: no changes in docosahexaenoic acid speciesKei Hamazaki
Laboratory of Molecular Signaling, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N07, MSC9410, Bethesda, MD 20892 9410, USA
J Psychiatr Res 44:688-93. 2010..The selective decrease in 22:5n-6 without affecting DHA contents suggests altered lipid metabolism, particularly n-6 PUFA rather than n-3 PUFA, in the hippocampus of individuals with schizophrenia or bipolar disorder... - Docosahexaenoic acid is an independent predictor of all-cause mortality in hemodialysis patientsKei Hamazaki
Department of Public Health, Faculty of Medicine, University of Toyama, Japan
Am J Nephrol 33:105-10. 2011..The aim of this study was to determine whether DHA levels in RBCs predict the mortality of patients on HD in a prospective cohort study... - Effect of omega-3 fatty acid-containing phospholipids on blood catecholamine concentrations in healthy volunteers: a randomized, placebo-controlled, double-blind trialKei Hamazaki
Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Japan
Nutrition 21:705-10. 2005..This effect of EPA plus DHA to lower plasma NE concentrations may be important to understand some of the effects of fish oils on diseases... - Suicide attempt and n-3 fatty acid levels in red blood cells: a case control study in ChinaMingming Huan
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama-city, Japan
Biol Psychiatry 56:490-6. 2004..0001) after adjustment for possible confounding factors CONCLUSIONS: Our findings suggest that low n-3 fatty acid levels in tissues were a risk factor of suicide attempt. Further studies including intervention with fish oil are warranted... - The effects of eicosapentaenoic acid-fortified food on inflammatory markers in healthy subjects--A randomized, placebo-controlled, double-blind studyShuntaro Fujioka
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan
J Nutr Sci Vitaminol (Tokyo) 52:261-5. 2006..68%). The inflammatory markers did not change in either group. It is likely that fish oil does not change hs-CRP or sTNF-Rs 1 or 2 in subjects without active inflammation... - The effects of docosahexaenoic acid-rich fish oil on behavior, school attendance rate and malaria infection in school children--a double-blind, randomized, placebo-controlled trial in Lampung, IndonesiaKei Hamazaki
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 930 0194, Japan
Asia Pac J Clin Nutr 17:258-63. 2008..There are only a very limited number of reports of intervention studies on the effects of fish oil on behavior in normal school children... - The relationship between tissue RBC n-3 fatty acids and pulse wave velocityHiroto Nishizawa
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama-city, Toyama 9300194, Japan
In Vivo 20:307-10. 2006..Although baPWV values may not directly indicate arteriosclerosis, the present study suggests that long-term n-3 fatty acid intake is beneficial for the vascular system... - Factors influencing EPA+DHA levels in red blood cells in JapanMiho Itomura
Section of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama 930 0194, Japan
In Vivo 22:131-5. 2008..31), (ii) age (beta=0.33), (iii) gender (beta=-0.15) and (iv) physical activity (beta=-0.11) but not with body mass index or smoking... - The effect of fish oil on physical aggression in schoolchildren--a randomized, double-blind, placebo-controlled trialMiho Itomura
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan 9300194
J Nutr Biochem 16:163-71. 2005..In males, impulsivity reduced in both groups without any intergroup differences. CONCLUSION: There is a possibility that changes in fatty acid nutrition might affect physical aggression especially in girls... - Fish oil reduces tooth loss mainly through its anti-inflammatory effects?Kei Hamazaki
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 930 0194, Japan
Med Hypotheses 67:868-70. 2006..This hypothesis may explain the linkage between periodontitis/tooth loss and coronary heart disease... - The effect of n - 3 PUFA/gamma-cyclodextrin complex on serum lipids in healthy volunteers--a randomized, placebo-controlled, double-blind trialKoji Kobayashi
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama City, Toyama 9300194, Japan
Asia Pac J Clin Nutr 16:429-34. 2007.... - n-3 long-chain FA decrease serum levels of TG and remnant-like particle-cholesterol in humansKei Hamazaki
Department of Clinical Application, Institute of Natural Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama-shi, Toyama 930-0194, Japan
Lipids 38:353-8. 2003..The groups did not differ in the other lipid levels. It is likely that n-3 long-chain FA may exert anti-atherosclerotic effects by lowering serum TG and RLP-cholesterol levels even at the dose of 860 mg/d... - Effects of cooking plant oils on recurrent aphthous stomatitis: a randomized, placebo-controlled, double-blind trialKei Hamazaki
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama, Japan
Nutrition 22:534-8. 2006..However, well-controlled dietary intervention studies to prevent minor RAS are very rare. The objective of the present study was to investigate whether the prevalence of RAS decreased with perilla oil (rich in alpha-linolenic acid)... - Relationships among skin conditions, mood, and polyunsaturated fatty acids of RBCs in healthy womenNina Hamazaki-Fujita
Kracie Pharma, Ltd, Takaoka City, Toyama, Japan
J Cosmet Sci 63:303-10. 2012..Pigmentation characteristics in the forehead were independent from other areas of the face. Negative mood and AA were adversely correlated with skin conditions... - Fish oils and aggression or hostilityTomohito Hamazaki
Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2680 Sugitani, Toyama City, Toyama 9300194, Japan
Prog Lipid Res 47:221-32. 2008..Among them, activation of the serotonergic neuron system is the most promising. The research area of fish oils and aggression/hostility is clearly important from the medical and social points of view... - The effect of eicosapentaenoic acid on prostate-specific antigenKei Hamazaki
Division of Clinical Application, Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, Toyama, Japan
In Vivo 20:397-401. 2006..5+/-14.0%). There were no significant differences between the two groups in the serum PSA levels, allowing the conclusion that the PSA is an appropriate surrogate marker of recurrence in prostate cancer... - A critical evaluation of influence of ethanol and diet on salsolinol enantiomers in humans and ratsJeongrim Lee
Laboratory of Molecular Signaling, National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA
Alcohol Clin Exp Res 34:242-50. 2010..Using a newly developed mass spectrometric method to analyze SAL stereoisomers, we evaluated the contribution of ethanol, diet, and genetic background to SAL levels as well as its enantiomeric distribution... - Differential modification of the phospholipid profile by transient ischemia in rat hippocampal CA1 and CA3 regionsKei Hamazaki
Laboratory of Molecular Signaling, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Room 3N 07, Bethesda, MD 20892 9410, United States
Prostaglandins Leukot Essent Fatty Acids 88:299-306. 2013..Also, selective activation of phospholipase A2, which primarily releases polyunsaturated fatty acids, might not be characteristic to cell death in CA1... - Molecular mechanisms involved in the adaptive response to cadmium-induced apoptosis in human myelomonocytic lymphoma U937 cellsZheng Guo Cui
Department of Public Health, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama 930 0194, Japan
Toxicol In Vitro 25:1687-93. 2011..The mechanism involves inhibition of intracellular ROS generation and JNK activation, and modulating the balance between the expression of Mcl-1 and its binding partners, Bim, Noxa and tBid... - The depressive effects of 5,8,11-eicosatrienoic Acid (20:3n-9) on osteoblastsTomohito Hamazaki
Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama 9300194, Japan
Lipids 44:97-102. 2009..The presence of 20:3n-9 in fetal cartilage may be important for the prevention of calcification in the cartilage. 20:3n-9 could be applied to some clinical situations where bone formation should be inhibited...