S Amano

Summary

Affiliation: University of Tokyo
Country: Japan

Publications

  1. ncbi Properties of corneas reconstructed with cultured human corneal endothelial cells and human corneal stroma
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 49:448-52. 2005
  2. ncbi Corneal irregular astigmatism after hyperopic laser in situ keratomileusis
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Cornea 24:789-92. 2005
  3. ncbi Transplantation of cultured human corneal endothelial cells
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Cornea 22:S66-74. 2003
  4. ncbi Antigenicity of porcine cornea as xenograft
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Curr Eye Res 26:313-8. 2003
  5. ncbi Ocular manifestations of congenital insensitivity to pain with anhidrosis
    Shiro Amano
    Department of Ophthalmology, Tokyo University Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Am J Ophthalmol 141:472-7. 2006
  6. ncbi Comparison of central corneal thickness measurements by rotating Scheimpflug camera, ultrasonic pachymetry, and scanning-slit corneal topography
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 113:937-41. 2006
  7. ncbi Corneal stromal and endothelial cell precursors
    Shiro Amano
    Department of Ophthalmology, Tokyo University School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 114 8655, Japan
    Cornea 25:S73-7. 2006
  8. ncbi Advanced glycation end products in human optic nerve head
    S Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Br J Ophthalmol 85:52-5. 2001
  9. ncbi Herpes simplex virus in the trabeculum of an eye with corneal endotheliitis
    S Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Japan
    Am J Ophthalmol 127:721-2. 1999
  10. ncbi Age-related changes in corneal and ocular higher-order wavefront aberrations
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Am J Ophthalmol 137:988-92. 2004

Collaborators

Detail Information

Publications104 found, 100 shown here

  1. ncbi Properties of corneas reconstructed with cultured human corneal endothelial cells and human corneal stroma
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 49:448-52. 2005
    ..To examine the properties of corneas tissue-engineered with cultured human corneal endothelial cells (HCEC) and human corneal stroma...
  2. ncbi Corneal irregular astigmatism after hyperopic laser in situ keratomileusis
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Cornea 24:789-92. 2005
    ..To evaluate the changes in irregular astigmatism after hyperopic laser in situ keratomileusis (LASIK)...
  3. ncbi Transplantation of cultured human corneal endothelial cells
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Cornea 22:S66-74. 2003
    ..To investigate the feasibility of corneal reconstruction utilizing cultured human corneal endothelial cells (HCECs)...
  4. ncbi Antigenicity of porcine cornea as xenograft
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Curr Eye Res 26:313-8. 2003
    ..To investigate the antigenicity of porcine corneal stroma as xenograft to man...
  5. ncbi Ocular manifestations of congenital insensitivity to pain with anhidrosis
    Shiro Amano
    Department of Ophthalmology, Tokyo University Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Am J Ophthalmol 141:472-7. 2006
    ..To describe ocular manifestations in Japanese patients with congenital insensitivity to pain with anhidrosis (CIPA), focusing particularly on the status of the ocular surface...
  6. ncbi Comparison of central corneal thickness measurements by rotating Scheimpflug camera, ultrasonic pachymetry, and scanning-slit corneal topography
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 113:937-41. 2006
    ..To compare central corneal thickness measurements and their reproducibility when taken by a rotating Scheimpflug camera, ultrasonic pachymetry, and scanning-slit corneal topography/pachymetry...
  7. ncbi Corneal stromal and endothelial cell precursors
    Shiro Amano
    Department of Ophthalmology, Tokyo University School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 114 8655, Japan
    Cornea 25:S73-7. 2006
    ..To isolate precursors of human corneal stromal and endothelial cells in vitro and to compare the distribution of rabbit corneal endothelial cell precursors in the central and peripheral regions of the cornea...
  8. ncbi Advanced glycation end products in human optic nerve head
    S Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Br J Ophthalmol 85:52-5. 2001
    ..To localise advanced glycation end products (AGEs) in human optic nerve head...
  9. ncbi Herpes simplex virus in the trabeculum of an eye with corneal endotheliitis
    S Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Japan
    Am J Ophthalmol 127:721-2. 1999
    ..To report an eye with corneal endotheliitis and increased intraocular pressure in which the trabeculum demonstrated immunoreactivity for herpes simplex virus...
  10. ncbi Age-related changes in corneal and ocular higher-order wavefront aberrations
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Am J Ophthalmol 137:988-92. 2004
    ..To investigate age-related changes in ocular and corneal higher-order wavefront aberrations and elucidate relative contributions of the cornea and the lens in the age-related changes...
  11. ncbi Comparative study of intraoperative mitomycin C and beta irradiation in pterygium surgery
    S Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Japan
    Br J Ophthalmol 84:618-21. 2000
    ..To compare the rate of recurrence and complication after surgery for primary pterygium performed by one surgeon using either intraoperative mitomycin C or beta irradiation...
  12. ncbi Relation between corneal haze and transforming growth factor-beta1 after photorefractive keratectomy and laser in situ keratomileusis
    Y Kaji
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    J Cataract Refract Surg 27:1840-6. 2001
    ..CONCLUSION: The multiplier effect of epithelial abrasion and excimer laser ablation in PRK may increase the expression of TGF-beta1 in keratocytes and induce corneal haze...
  13. ncbi Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell
    Y Kaji
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Curr Eye Res 23:469-77. 2001
    ..AGEs' formation in Descemet's membrane may be responsible for the corneal endothelial cell loss with aging and corneal endothelial abnormalities in diabetic patients..
  14. ncbi Sphere therapy for corneal endothelium deficiency in a rabbit model
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan
    Invest Ophthalmol Vis Sci 46:3128-35. 2005
    ..CONCLUSIONS: Precursors from rabbit CE were isolated by a sphere-forming assay. Rabbit CE-derived sphere therapy is an effective treatment in a rabbit CE deficiency model...
  15. ncbi Human corneal epithelial equivalents for ocular surface reconstruction in a complete serum-free culture system without unknown factors
    Seiichi Yokoo
    Departments of Corneal Tissue Regeneration, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 49:2438-43. 2008
    ....
  16. ncbi Autologous transplantation of conjunctival epithelial cells cultured on amniotic membrane in a rabbit model
    Kyoko Ono
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Mol Vis 13:1138-43. 2007
    ..To evaluate the feasibility of autologous transplantation in a rabbit model of conjunctival epithelial cells cultured on amniotic membrane for ocular surface reconstruction...
  17. ncbi Ocular and systemic factors relevant to diabetic keratoepitheliopathy
    K Inoue
    Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Cornea 20:798-801. 2001
    ..This study examines the contribution of ocular and systemic factors to diabetic keratoepitheliopathy...
  18. ncbi Penetrating keratoplasty for bullous keratopathy after trabeculectomy
    S Fukuoka
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Eye (Lond) 23:940-4. 2009
    ..To evaluate the results of penetrating keratoplasty (PK) in eyes with bullous keratopathy having previously undergone trabeculectomy...
  19. ncbi Treatment of rabbit bullous keratopathy with precursors derived from cultured human corneal endothelium
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Japan
    Invest Ophthalmol Vis Sci 46:3637-44. 2005
    ..Injection of precursors derived from cultured HCE into the anterior chamber is an effective treatment strategy for CE deficiency in a rabbit model...
  20. ncbi Preservation of donor cornea prevents corneal allograft rejection by inhibiting induction of alloimmunity
    K Kamiya
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Exp Eye Res 70:737-43. 2000
    ..These results indicate that the reduction of MHC class I antigens and minor H antigens expression in the preserved grafts induces a failure of allo-sensitization and leads to the high rate of acceptance in corneal allografts...
  21. ncbi Quantitative analysis of regular and irregular astigmatism induced by pterygium
    A Tomidokoro
    Department of Ophthalmology, Omiya Red Cross Hospital, Saitama, Japan
    Cornea 18:412-5. 1999
    ..To quantitatively evaluate the influence of pterygium and its removal surgery on both regular and irregular corneal astigmatism...
  22. ncbi A mouse model of allogeneic corneal endothelial cell transplantation
    Takahiko Hayashi
    Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
    Cornea 27:699-705. 2008
    ..However, the immunologic changes after allo-CEC transplantation are poorly understood at present. We tried to establish a mouse model of allogeneic CEC transplantation for immunologic studies...
  23. ncbi Immunologic mechanisms of corneal allografts reconstituted from cultured allogeneic endothelial cells in an immune-privileged site
    Takahiko Hayashi
    Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Kanagawa, Japan
    Invest Ophthalmol Vis Sci 50:3151-8. 2009
    ..To analyze outcomes and immunologic features after cultured corneal endothelial cell (CEC) transplantation in a murine model...
  24. ncbi Corneal irregular astigmatism and contrast sensitivity after photorefractive keratectomy
    A Tomidokoro
    Department of Ophthalmology, Omiya Red Cross Hospital, 8 3 33 Kamiochiai Yono shi, Saitama, 338 0001, Japan
    Ophthalmology 108:2209-12. 2001
    ..To investigate the relation between contrast sensitivity and corneal irregular astigmatism in eyes after photorefractive keratectomy (PRK)...
  25. ncbi Secondary closure of neodymium:YAG laser posterior capsulotomy
    T Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    J Cataract Refract Surg 27:1695-7. 2001
    ..Although IOL exchange surgery was considered, a second Nd:YAG laser intervention successfully removed the proliferated lens materials and restored the visual acuity. The glistenings were not the cause of the reduced vision...
  26. ncbi Pinguecula and contact lenses
    T Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Eye (Lond) 24:1685-91. 2010
    ..To assess the relationship between age and the incidence and severity (determined by a grading system) of pinguecula in contact lens (CL) wearers, and to compare the grade of pinguecula between CL wearers and non-wearers...
  27. ncbi Relationship between refraction and allergic conjunctivitis
    T Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Eye (Lond) 23:63-6. 2009
    ..We investigated the relationship between refractive error and allergic conjunctivitis in order to reveal possible insights into the pathogenesis in 1015 subjects...
  28. ncbi The effects of proinflammatory cytokines on cytokine-chemokine gene expression profiles in the human corneal endothelium
    Hiroko Yamagami
    Department of Ophthalmology, Omiya Medical Center, Jichi Medical School, Saitama, Japan
    Invest Ophthalmol Vis Sci 44:514-20. 2003
    ..To determine the effects of proinflammatory cytokines on differential gene expression profiles in the human corneal endothelium (HCE), by using a cDNA expression array...
  29. ncbi Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis
    T Usui
    Department of Ophthalmology, Faculty of Medicine, Tokyo University, Bunkyo-ku, Tokyo, Japan
    J Clin Invest 108:107-15. 2001
    ..These results indicate that the normal transport activity of NBC-1 is indispensable not only for the maintenance of corneal and lenticular transparency but also for the regulation of aqueous humor outflow...
  30. ncbi Expression of vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 in corneal lymphangiogenesis
    T Mimura
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Exp Eye Res 72:71-8. 2001
    ..These data suggest that VEGF-C and VEGFR-3 are pathophysiologically relevant endogenous factors in corneal lymphangiogenesis...
  31. ncbi Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2
    Hiroshi Mochimaru
    Laboratory of Retinal Cell Biology, Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo, Japan
    Invest Ophthalmol Vis Sci 49:2172-7. 2008
    ..To investigate whether the induction of cytotoxic T lymphocytes (CTLs) targeting VEGF receptor 2 inhibits corneal neovascularization caused by alkali injury...
  32. ncbi Histocompatibility Y antigen compatibility and allograft rejection in corneal transplantation
    K Inoue
    Department of Ophthalmology, Branch Hospital, Faculty of Medicine, University of Tokyo, Japan
    Eye (Lond) 14:201-5. 2000
    ..To assess the effects of histocompatibility Y (H-Y) antigen matching on the rate of corneal allograft rejection after penetrating keratoplasty (PKP)...
  33. ncbi Piggyback foldable intraocular lens implantation in patients with microphthalmos
    T Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    J Cataract Refract Surg 27:841-4. 2001
    ..To evaluate the clinical results of phacoemulsification and implantation of 2 foldable acrylic intraocular lenses (IOLs) in microphthalmic eyes...
  34. ncbi Risk factors for corneal graft failure and rejection in penetrating keratoplasty
    K Inoue
    Department of Ophthalmology, University of Tokyo, School of Medicine, Tokyo, Japan
    Acta Ophthalmol Scand 79:251-5. 2001
    ..To evaluate risk factors for graft failure and allograft rejection after penetrating keratoplasty (PK)...
  35. ncbi Longitudinal analysis of corneal topography in suspected keratoconus
    M Shirayama-Suzuki
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Br J Ophthalmol 93:815-9. 2009
    ..To examine the incidence of progression of suspected keratoconus to true keratoconus and compare quantitative descriptors of corneal topography between eyes with and without progression...
  36. ncbi Advanced glycation end product deposits in climatic droplet keratopathy
    Y Kaji
    Department of Ophthalmology, Tsukuba University Institute of Clinical Medicine, Tennoudai 1 1 1, Tsukuba, Ibaraki 305 8575, Japan
    Br J Ophthalmol 91:85-8. 2007
    ..However, the histochemical nature of the deposits seen in CDK is still unclear...
  37. ncbi Topical application of culture supernatant from human amniotic epithelial cells suppresses inflammatory reactions in cornea
    Kazutaka Kamiya
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Exp Eye Res 80:671-9. 2005
    ..These results suggest that HAEC are a source of soluble anti-inflammatory factors and that conditioned medium from HAEC contains factors other than IL-1ra that suppress corneal inflammation...
  38. ncbi A novel isolation technique of progenitor cells in human corneal epithelium using non-tissue culture dishes
    Seiichi Yokoo
    Department of Corneal Tissue Regeneration, Tokyo University Graduate School of Medicine, Tokyo, Japan
    Stem Cells 26:1743-8. 2008
    ..These findings indicate that our new technique using non-tissue culture dishes allows the isolation of progenitor cells from human corneal limbal epithelium and that laminin-5 has a critical role in the adhesion of these cells...
  39. ncbi Corneal endothelial cell density and associated factors in a population-based study in Japan: the Kumejima study
    Akiko Higa
    Department of Ophthalmology, University of the Ryukyus Faculty of Medicine, Okinawa, Japan
    Am J Ophthalmol 149:794-9. 2010
    ..To examine the distribution of corneal endothelial cell density (ECD) and relating factors in ophthalmologically normal Japanese in a population-based setting...
  40. ncbi Inhibition of murine corneal allograft rejection by treatment with antibodies to CD80 and CD86
    Fumie Kagaya
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Exp Eye Res 74:131-9. 2002
    ..These results demonstrated a significant role of CD80 and CD86 costimulatory molecules in corneal allograft rejection...
  41. ncbi Magnetic attraction of iron-endocytosed corneal endothelial cells to Descemet's membrane
    Tatsuya Mimura
    Department of Ophthalmology, School of Medicine, University of Tokyo, Tokyo, 113 8655, Japan
    Exp Eye Res 76:745-51. 2003
    ..To evaluate the feasibility of a novel method of magnetic attraction of iron-endocytosed corneal endothelial cells to Descemet's membrane...
  42. ncbi Effect of latanoprost on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase 1 on the ocular surface
    Norihiko Honda
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Arch Ophthalmol 128:466-71. 2010
    ..To investigate the effect of topical latanoprost on the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase 1 (TIMP-1) on the ocular surface...
  43. ncbi UV absorption in human oral mucosal epithelial sheets for ocular surface reconstruction
    Seiichi Yokoo
    Department of Corneal Tissue Regeneration, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Ophthalmic Res 38:350-4. 2006
    ....
  44. ncbi Human corneal endothelial cell precursors isolated by sphere-forming assay
    Seiichi Yokoo
    Department of Corneal Tissue Regeneration, Tokyo University Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Invest Ophthalmol Vis Sci 46:1626-31. 2005
    ..CONCLUSIONS: These findings indicate that the HCEC contains precursor cells with a propensity to differentiate into HCECs and that these cells can also produce neuronal and mesenchymal cell proteins...
  45. ncbi Five-year follow-up of photorefractive keratectomy for myopia
    Norihiko Honda
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    J Refract Surg 20:116-20. 2004
    ..Myopic regression occurred in the first year, with continued mild regression of approximately -0.75 D between 2 and 5 years. Nevertheless, the results show the procedure was relatively safe and effective in this group...
  46. ncbi Selective isolation of young cells from human corneal endothelium by the sphere-forming assay
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Tissue Eng Part C Methods 16:803-12. 2010
    ..Thus, the sphere-forming assay may contribute to obtaining the young cells needed for regenerative medicine...
  47. ncbi Longitudinal changes in corneal irregular astigmatism and visual acuity in eyes with keratoconus
    Mariko Suzuki
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 51:265-9. 2007
    ..To quantitatively investigate the time course of changes in corneal irregular astigmatism and their relation to best spectacle-corrected visual acuity (BSCVA) in eyes with keratoconus...
  48. ncbi Transplantation of a sheet of human corneal endothelial cell in a rabbit model
    Kouichiro Hitani
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Mol Vis 14:1-9. 2008
    ..To develop a novel method for constructing a sheet of human corneal endothelial cells (HCECs) and examine the properties of the HCEC sheet...
  49. ncbi Comparison of rabbit corneal endothelial cell precursors in the central and peripheral cornea
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Japan
    Invest Ophthalmol Vis Sci 46:3645-8. 2005
    ....
  50. ncbi Sphere formation and expression of neural proteins by human corneal stromal cells in vitro
    Saiko Uchida
    Department of Ophthalmology, Tokyo University School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Invest Ophthalmol Vis Sci 46:1620-5. 2005
    ..To demonstrate the presence of corneal stromal precursors that express neural markers in vitro...
  51. ncbi Intraocular dexamethasone delivery system for corneal transplantation in an animal model
    Fumie Kagaya
    Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113 8655, Japan
    Cornea 21:200-2. 2002
    ..The administration of DEX DDS significantly prolonged the survival rate of the corneal grafts (p < 0.001, log-rank test). CONCLUSION: DEX DDS is effective in suppressing graft rejection in high-risk corneal transplantation...
  52. ncbi Correlations between allergen-specific IgE serum levels in patients with allergic conjunctivitis in spring
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ocul Immunol Inflamm 12:45-51. 2004
    ..The purpose of this study was to evaluate the relation between various specific class E immunoglobulins (IgE) in serum and allergic conjunctivitis in spring...
  53. ncbi Expression and function of receptors for advanced glycation end products in bovine corneal endothelial cells
    Yuichi Kaji
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 44:521-8. 2003
    ....
  54. ncbi Higher order wavefront aberrations of cornea and magnitude of refractive correction in laser in situ keratomileusis
    Tetsuro Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 109:1154-8. 2002
    ....
  55. ncbi [Significance of leukocytes in the regulation of retinal edema, ischemia, and angiogenesis]
    Susumu Ishida
    Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
    Nippon Ganka Gakkai Zasshi 108:193-201. 2004
    ..CONCLUSION: Leukocytes are considered to regulate retinal edema, ischemia, and angiogenesis...
  56. ncbi Anterior capsular contraction after cataract surgery in vitrectomized eyes
    H Matsuda
    Kaiya Eye Clinic, Hamamatsu, Tokyo, Japan
    Am J Ophthalmol 132:108-9. 2001
    ..CONCLUSION: Eyes after simple vitrectomy are not at a higher risk of ACO contraction following cataract surgery...
  57. ncbi Quantification of simulated corneal haze by measuring back-scattered light
    K Soya
    Division of Ophthalmology, Tokyo Senbai Hospital, Tokyo, Japan
    Ophthalmic Res 34:380-8. 2002
    ..The ratio of integrated scattering values was proportional to that of the light path length. It was shown that the TSPC-3 hazemeter possesses sufficient capability for a quantitative evaluation of corneal haze...
  58. ncbi Allergens in Japanese patients with allergic conjunctivitis in autumn
    T Mimura
    Department of Ophthalmology, University of Tokyo, Graduate School of Medicine, Tokyo, Japan
    Eye (Lond) 19:995-9. 2005
    ..The purpose of the current study is to evaluate the relation between various specific class E immunoglobulins (IgE) in the serum and allergic conjunctivitis in autumn...
  59. ncbi Factors contributing to corneal complications after vitrectomy in diabetic patients
    M Hiraoka
    Department of Ophthalmology, Diabetes Center, Tokyo Women's Medical College, Tokyo, Japan
    Jpn J Ophthalmol 45:492-5. 2001
    ..CONCLUSION: Surgical invasion is a risk factor for corneal complications after vitrectomy in diabetic patients...
  60. ncbi Hyaluronan synthase expression in bovine eyes
    T Usui
    Department of Ophthalmology, University of Tokyo, Japan
    Invest Ophthalmol Vis Sci 40:563-7. 1999
    ..Hyaluronan is produced by HA synthase (HAS), which has three isoforms: HAS1, HAS2, and HAS3. In this study, the HAS expression in the anterior segment of bovine eyes was investigated to determine the significance of HA in eyes...
  61. ncbi Long-term outcome of systemic cyclosporine treatment following penetrating keratoplasty
    K Inoue
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 45:378-82. 2001
    ..CONCLUSION: Systemic cyclosporine treatment for several months did not reduce the incidence of rejection nor improve the rate of graft clarity in the long term in high-risk patients after PKP...
  62. ncbi Role of macrophage migration inhibitory factor in corneal neovascularization
    Tomohiko Usui
    Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Tokyo Japan
    Invest Ophthalmol Vis Sci 48:3545-50. 2007
    ..To determine the role of macrophage migration inhibitory factor (MIF) in inflammatory corneal neovascularization...
  63. ncbi Severe hyperopic shift and irregular astigmatism after radial keratotomy
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Japan
    Eye Contact Lens 35:345-7. 2009
    ..To report a case of acute high hyperopia occurring after radial keratotomy and evaluate the extent of corneal wavefront aberration with a Hartmann-Shack aberrometer...
  64. ncbi Necessary prone position time for human corneal endothelial precursor transplantation in a rabbit endothelial deficiency model
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Curr Eye Res 32:617-23. 2007
    ..This time, we investigated the necessary postoperative time in the prone position for clinical application of precursor cell transplantation...
  65. ncbi Characterization of bone marrow derived cells in the substantia propria of the human conjunctiva
    Satoru Yamagami
    Department of Corneal Tissue Regeneration, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 48:4476-81. 2007
    ..To characterize the main population of bone marrow-derived cells (BMCs) in human normal subconjunctiva and make a comparison with BMCs in the corneal stroma and epithelium...
  66. ncbi Role of resident corneal leukocytes and draining cervical lymph nodes in corneal allograft rejection
    Satoru Yamagami
    Department of Corneal Tissue Regeneration, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Cornea 22:S61-5. 2003
    ....
  67. ncbi Isolation of adult progenitor cells with neuronal potential from rabbit corneal epithelial cells in serum- and feeder layer-free culture conditions
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Mol Vis 16:1712-9. 2010
    ....
  68. ncbi Photodynamic therapy for corneal neovascularization using polymeric micelles encapsulating dendrimer porphyrins
    Kenji Sugisaki
    Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Hongo, Bunkyo ku, Japan
    Invest Ophthalmol Vis Sci 49:894-9. 2008
    ....
  69. ncbi Isolation and distribution of rabbit keratocyte precursors
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Mol Vis 14:197-203. 2008
    ..To isolate multipotent precursors from the rabbit corneal stroma and to compare the distribution and proliferative capacity of keratocyte precursors obtained from the central and peripheral regions of the corneal stroma...
  70. ncbi [Transplantation of corneal endothelial cells]
    Shiro Amano
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    Nippon Ganka Gakkai Zasshi 106:805-35; discussion 836. 2002
    ..4. The direct delivery of cultured HCECs into the anterior chamber can be an alternative method of choice when its long-term safety is confirmed...
  71. ncbi Fourier series harmonic analysis of corneal topography following suture removal after penetrating keratoplasty
    Fumie Kagaya
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Cornea 21:256-9. 2002
    ..0001) and higher order irregularity (p < 0.0001). CONCLUSIONS: Suture removal after penetrating keratoplasty induces myopic shift and reduction in irregular astigmatism of the cornea...
  72. ncbi Distribution of precursors in human corneal stromal cells and endothelial cells
    Satoru Yamagami
    Department of Corneal Tissue Regeneration, Tokyo University Graduate School of Medicine, Tokyo, Japan
    Ophthalmology 114:433-9. 2007
    ....
  73. ncbi Retinal vasculitis and vitreous hemorrhage associated with mixed connective tissue disease: retinal vasculitis in MCTD
    Tatsuya Mimura
    Department of Ophthalmology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Int Ophthalmol 26:159-61. 2005
    ..Retinal vasculitis associated with mixed connective tissue disease (MCTD) has rarely been reported in the literature. We describe a rare case of a patient with serious retinal vasculopathy and vitreous hemorrhages associated with MCTD...
  74. ncbi Conjunctivochalasis and contact lenses
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Am J Ophthalmol 148:20-5.e1. 2009
    ....
  75. ncbi Relationship between human leukocyte antigen status and proliferative diabetic retinopathy in patients with younger-onset type 1 diabetes mellitus
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Am J Ophthalmol 135:844-8. 2003
    ..To investigate the relationship between human leukocyte antigen (HLA) status and proliferative diabetic retinopathy (PDR) to assess the genetic basis of PDR in younger type 1 diabetic patients...
  76. ncbi Vasovagal syncope evoked by needle phobia when inserting a contact lens
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655 Japan
    Ophthalmic Physiol Opt 25:171-3. 2005
    ..To report a patient who fell unconscious because of vasovagal syncope evoked by needle phobia when he tried to wear contact lenses...
  77. ncbi Gene expression profile in corneal neovascularization identified by immunology related macroarray
    Tomohiko Usui
    Department of Ophthalmology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    Mol Vis 10:832-6. 2004
    ..To identify differentially expressed genes in corneal neovascularization using cDNA macroarray...
  78. ncbi In vivo confocal microscopy of human cornea covered with human amniotic membrane
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 52:493-6. 2008
    ..We investigated the use of confocal microscopy for observation of human corneas covered with amniotic membrane...
  79. ncbi Distinct populations of dendritic cells in the normal human donor corneal epithelium
    Satoru Yamagami
    Department of Corneal Tissue Regeneration, University of Tokyo Graduate School of Medicine, Hongo, Japan
    Invest Ophthalmol Vis Sci 46:4489-94. 2005
    ..To characterize dendritic cells (DC) in normal human corneal epithelium...
  80. ncbi Immunochromatographic assay for measurement of total IgE in tears, nasal mucus, and saliva of patients with allergic rhinoconjunctivitis
    Tatsuya Mimura
    Department of Ophthalmology, Toranomon Hospital, Minato ku, Tokyo, Japan
    J Asthma 47:1153-60. 2010
    ..We evaluated whether the measurement of local production of IgE in tears, saliva, and nasal mucus was useful for the diagnosis of allergic rhinoconjunctivitis...
  81. ncbi Bone marrow-derived cells in normal human corneal stroma
    Satoru Yamagami
    Departments of Corneal Tissue Regeneration and Ophthalmology, University of Tokyo Graduate School of Medicine, Hongo 7 3 1, Bunkyo ku, Tokyo, Japan 113 8655
    Arch Ophthalmol 124:62-9. 2006
    ..To examine the normal human corneal stroma for the presence of bone marrow-derived cells...
  82. ncbi Damaged DNA-binding protein 2 accelerates UV-damaged DNA repair in human corneal endothelium
    Taeko Inoki
    Department of Ophthalmology, Jichi Medical School, Tochigi, Japan
    Exp Eye Res 79:367-76. 2004
    ..Our findings show a critical role for damaged DNA-binding protein 2 in DNA repair to maintain the human corneal endothelium function...
  83. ncbi In vivo confocal microscopy of hereditary sensory and autonomic neuropathy
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Bunkyo ku, Tokyo, Japan
    Curr Eye Res 33:940-5. 2008
    ....
  84. ncbi Isolation of human corneal endothelial cell precursors and construction of cell sheets by precursors
    Satoru Yamagami
    Department of Corneal Tissue Regeneration, Tokyo University Graduate School of Medicine, Hongo 7 3 1, Bunkyo ku, Tokyo 113 8655, Japan
    Cornea 25:S90-2. 2006
    ..To review recently published experimental data on human corneal endothelium (CE) precursors...
  85. ncbi Transplantation of corneas reconstructed with cultured adult human corneal endothelial cells in nude rats
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Exp Eye Res 79:231-7. 2004
    ..The feasibility of corneal reconstruction with cultured adult human corneal endothelial cells (HCEC) was examined in a nude rat model...
  86. ncbi Recent causes of subconjunctival hemorrhage
    Tatsuya Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Ophthalmologica 224:133-7. 2010
    ..To assess the relationship between the incidence of subconjunctival hemorrhage (SCH) and age during each season of the year, and to examine recent risk factors for SCH...
  87. ncbi Preoperative evaluation of cultured human corneal limbal epithelium on amniotic membrane by confocal microscopy
    Tatsuya Mimura
    Department of Ophthalmology, University of Illinois at Chicago, 1855 W Taylor Street, Chicago, IL 60612, USA
    Curr Eye Res 32:407-11. 2007
    ..We propose the use of in vivo confocal microscopy as a novel method for the evaluation of limbal corneal epithelium cultured on amniotic membrane...
  88. ncbi Influence of glistenings on the optical quality of acrylic foldable intraocular lens
    T Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Br J Ophthalmol 85:1034-7. 2001
    ..To assess the influence of glistenings on the optical quality of acrylic foldable intraocular lens...
  89. ncbi Current trends in cataract and refractive surgery in Japan: 1999 survey
    T Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 45:383-7. 2001
    ..Refractive surgery is not yet widely performed, but laser in situ keratomileusis is viewed as the most promising procedure...
  90. ncbi Development and progression of diabetic retinopathy in patients with Type 1 diabetes who are positive for GAD autoantibody
    T Mimura
    Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    Diabet Med 21:559-62. 2004
    ..To investigate the relationship between autoantibodies to glutamic acid decarboxylase (GAD) and proliferative diabetic retinopathy (PDR) to assess the role of autoimmunity in retinopathy...
  91. ncbi Prevalence of and risk factors for cornea guttata in a population-based study in a southwestern island of Japan: the Kumejima study
    Akiko Higa
    Department of Ophthalmology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan
    Arch Ophthalmol 129:332-6. 2011
    ..To examine the prevalence of and risk factors for cornea guttata in a rural southwestern island of Japan...
  92. ncbi VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2
    Tomohiko Usui
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 45:368-74. 2004
    ..CONCLUSIONS: Taken together, these data identify VEGF(164(165)) as a proinflammatory isoform and identify multiple mechanisms underlying its proinflammatory biology...
  93. ncbi VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization
    Susumu Ishida
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA
    J Exp Med 198:483-9. 2003
    ..These processes provide positive and negative angiogenic regulation, respectively. Together, new therapeutic approaches for selectively targeting pathological, but not physiological, retinal neovascularization are outlined...
  94. ncbi VEGF164 is proinflammatory in the diabetic retina
    Susumu Ishida
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 44:2155-62. 2003
    ..The inhibition of diabetic retinal leukostasis and BRB breakdown with EYE001 in early and established diabetes indicates that VEGF(164) is an important isoform in the pathogenesis of early diabetic retinopathy...
  95. ncbi Corneal endothelial cell changes twenty years after penetrating keratoplasty
    Kenji Inoue
    Department of Ophthalmology, University of Tokyo, School of Medicine, Tokyo, Japan
    Jpn J Ophthalmol 46:189-92. 2002
    ..CONCLUSIONS: The corneal endothelial cells become stabilized 10 years after surgery in cases where the grafts remain transparent 20 years after surgery...
  96. ncbi Progression of keratoconus assessed by fourier analysis of videokeratography data
    Tetsuro Oshika
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 109:339-42. 2002
    ..To quantitatively document changes in corneal refractive parameters in relation to the progression of keratoconus over years...
  97. ncbi Decellularizing corneal stroma using N2 gas
    Shiro Amano
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Mol Vis 14:878-82. 2008
    ..To examine the efficacy of a novel method of decellularizing porcine corneal stroma using N(2) gas from liquid N(2) and the feasibility of using decellularized porcine corneal stroma in a corneal transplantation model in rabbits...
  98. ncbi Corneal higher order wavefront aberrations after hyperopic laser in situ keratomileusis
    Atsuko Nanba
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    J Refract Surg 21:46-51. 2005
    ..449, P = .094). CONCLUSIONS: Hyperopic LASIK significantly increases corneal coma-like and spherical-like aberrations and changes corneal spherical aberration from a positive to negative value...
  99. ncbi Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy
    Tatsuya Mimura
    Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114 2500, USA
    Ophthalmology 112:1904-9. 2005
    ..To investigate the relationship of HLA status and autoantibodies to glutamic acid decarboxylase (GAD) in proliferative diabetic retinopathy (PDR) to assess the role of autoimmunity and genetic markers in retinopathy...
  100. ncbi [Clinical results of amniotic membrane transplantation in Miyata Eye Hospital according to surgical methods]
    Ryuhei Hara
    Miyata Eye Hospital. 6-3 Kurahara, Miyakonojo 885-0051, Japan
    Nippon Ganka Gakkai Zasshi 109:580-90. 2005
    ....
  101. ncbi Effects of TGF-beta2 on immune response-related gene expression profiles in the human corneal endothelium
    Satoru Yamagami
    Department of Corneal Tissue Regeneration, Tokyo University Graduate School of Medicine, Tokyo, Japan
    Invest Ophthalmol Vis Sci 45:515-21. 2004
    ..To determine the effects of transforming growth factor (TGF)-beta2 on immune-response-related gene expression profiles in the stimulated human corneal endothelium (HCE)...