Yasumi Uchida

Summary

Country: Japan

Publications

  1. pmc Relationship between cardioscopic images and histological changes in the left ventricle of patients with idiopathic myocarditis
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Toho University Sakura Hospital and Funabashi Futawa Hospital, 2 30 17 Narashinodai, Funabashi, Japan
    Eur J Heart Fail 13:504-12. 2011
  2. pmc Localization of oxidized low-density lipoprotein and its relation to plaque morphology in human coronary artery
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    PLoS ONE 8:e55188. 2013
  3. pmc Molecular imaging of low-density lipoprotein in human coronary plaques by color fluorescent angioscopy and microscopy
    Yasumi Uchida
    Japanese Foundation for Cardiovascular Research, Funabashi, Japan
    PLoS ONE 7:e50678. 2012
  4. ncbi request reprint Cardioscopic detection of left ventricular thrombi. -With special reference to a comparison with left ventriculography and echocardiography-
    Yasuto Uchida
    Department of Cardiology, Toho University Medical Center Ohmori Hospital, Japan
    Circ J 75:1920-6. 2011
  5. doi request reprint Recent advances in coronary angioscopy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    J Cardiol 57:18-30. 2011
  6. doi request reprint Functional medial thickening and folding of the internal elastic lamina in coronary spasm
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, 2 30 17, Narashinodai, Funabashi, Japan 274 0063
    Am J Physiol Heart Circ Physiol 300:H423-30. 2011
  7. doi request reprint Role of calcium-activated potassium channels in the genesis of 3,4-diaminopyridine-induced periodic contractions in isolated canine coronary artery smooth muscles
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    J Pharmacol Exp Ther 338:974-83. 2011
  8. ncbi request reprint Histological characteristics of glistening yellow coronary plaques seen on angioscopy. -With special reference to vulnerable plaques-
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Japan
    Circ J 75:1913-9. 2011
  9. doi request reprint Two-dimensional visualization of cholesterol and cholesteryl esters within human coronary plaques by near-infrared fluorescence angioscopy
    Yasumi Uchida
    Department of Cardiology, Chiba Kensei Hospital, Japan
    Clin Cardiol 33:775-82. 2010
  10. ncbi request reprint Fluffy luminal surface of the non-stenotic culprit coronary artery in patients with acute coronary syndrome: an angioscopic study
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    Circ J 74:2379-85. 2010

Collaborators

Detail Information

Publications30

  1. pmc Relationship between cardioscopic images and histological changes in the left ventricle of patients with idiopathic myocarditis
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Toho University Sakura Hospital and Funabashi Futawa Hospital, 2 30 17 Narashinodai, Funabashi, Japan
    Eur J Heart Fail 13:504-12. 2011
    ..If the endocardial surface represents changes indicative of stages of myocarditis, staging of myocarditis and targeted cardioscope-guided biopsy could be used for accurate histological diagnosis...
  2. pmc Localization of oxidized low-density lipoprotein and its relation to plaque morphology in human coronary artery
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    PLoS ONE 8:e55188. 2013
    ..The present study was performed to visualize deposition sites and patterns of native oxLDL and their relation to plaque morphology in human coronary artery...
  3. pmc Molecular imaging of low-density lipoprotein in human coronary plaques by color fluorescent angioscopy and microscopy
    Yasumi Uchida
    Japanese Foundation for Cardiovascular Research, Funabashi, Japan
    PLoS ONE 7:e50678. 2012
    ..However, its localization in human coronary plaques is not well understood. The present study was performed to visualize LDL in human coronary artery wall...
  4. ncbi request reprint Cardioscopic detection of left ventricular thrombi. -With special reference to a comparison with left ventriculography and echocardiography-
    Yasuto Uchida
    Department of Cardiology, Toho University Medical Center Ohmori Hospital, Japan
    Circ J 75:1920-6. 2011
    ..Thrombosis occurs in the left ventricle and causes ischemic cerebral attacks. However, differences in the incidence of left ventricular thrombi (LVT) among various categories of heart diseases are not known...
  5. doi request reprint Recent advances in coronary angioscopy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    J Cardiol 57:18-30. 2011
    ..Therefore, development of a DES that causes an appropriate thickness (around 100 μm) of the neointima is a potential option with which to prevent neoendothelial cell damage and consequent LST while preventing restenosis...
  6. doi request reprint Functional medial thickening and folding of the internal elastic lamina in coronary spasm
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, 2 30 17, Narashinodai, Funabashi, Japan 274 0063
    Am J Physiol Heart Circ Physiol 300:H423-30. 2011
    ..We conclude that coronary spasm was elicited by radial rearrangement of the medial SMCs due to their own contraction and resultant medial thickening and folding of IEL, creating a piston effect to narrow the lumen, i.e., spasm...
  7. doi request reprint Role of calcium-activated potassium channels in the genesis of 3,4-diaminopyridine-induced periodic contractions in isolated canine coronary artery smooth muscles
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    J Pharmacol Exp Ther 338:974-83. 2011
    ..These processes were repeated spontaneously to cause PCs. H(+) and OH(-) were considered to act as the opener and closer of K(Ca), respectively...
  8. ncbi request reprint Histological characteristics of glistening yellow coronary plaques seen on angioscopy. -With special reference to vulnerable plaques-
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Japan
    Circ J 75:1913-9. 2011
    ..Collagen fiber (CF) is the main substance that protects coronary plaques against mechanical stress. Therefore, whether angioscopically defined vulnerable plaques correlate with those defined histologically was investigated...
  9. doi request reprint Two-dimensional visualization of cholesterol and cholesteryl esters within human coronary plaques by near-infrared fluorescence angioscopy
    Yasumi Uchida
    Department of Cardiology, Chiba Kensei Hospital, Japan
    Clin Cardiol 33:775-82. 2010
    ..If they are rendered visible in vivo, the progression of coronary plaques and the effects of respective therapies on these plaques can be objectively evaluated...
  10. ncbi request reprint Fluffy luminal surface of the non-stenotic culprit coronary artery in patients with acute coronary syndrome: an angioscopic study
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    Circ J 74:2379-85. 2010
    ..Approximately 15% of acute coronary syndrome (ACS) cases have no significant coronary stenosis. Mechanisms underlying the attacks are, however, unknown...
  11. ncbi request reprint Visualization of lipid components in human coronary plaques using color fluorescence angioscopy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Chiba, Japan
    Circ J 74:2181-6. 2010
    ....
  12. doi request reprint Role of a streamer-like coronary thrombus in the genesis of unstable angina
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    J Interv Cardiol 23:216-22. 2010
    ..This study was carried out to examine the incidence of this phenomenon and its relationship to the subtypes of UA...
  13. ncbi request reprint Formation of web- and membrane-like structures on the edges of bare-metal coronary stents
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    Circ J 74:1830-6. 2010
    ..Web-like (W) and membrane-like (M) structures have been observed on coronary stent edges on angioscopy but their incidence and mechanisms remain obscure...
  14. ncbi request reprint Possible participation of endothelial cell apoptosis of coronary microvessels in the genesis of Takotsubo cardiomyopathy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    Clin Cardiol 33:371-7. 2010
    ..Takotsubo cardiomyopathy (TCM) is characterized by systolic ballooning of the left ventricular apex. It is triggered by emotional or physical stress, but the exact mechanism through which stress leads to TCM is not known...
  15. doi request reprint Angioscopic detection of pulmonary thromboemboli: with special reference to comparison with angiography, intravascular ultrasonography, and computed tomography angiography
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Chiba, Japan
    J Interv Cardiol 23:470-8. 2010
    ....
  16. doi request reprint Detection of vulnerable coronary plaques by color fluorescent angioscopy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi and Tokyo, Japan
    JACC Cardiovasc Imaging 3:398-408. 2010
    ..This study was carried out to detect vulnerable coronary plaques by color fluorescent angioscopy...
  17. doi request reprint Characterization of coronary fibrin thrombus in patients with acute coronary syndrome using dye-staining angioscopy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Japan
    Arterioscler Thromb Vasc Biol 31:1452-60. 2011
    ..The present study was performed to visualize coronary fibrin thrombus and to examine its role in ACS...
  18. ncbi request reprint Nitroglycerin-induced heterogeneous subendocardial myocardial blood flow observed by cardioscopy in patients with coronary artery disease
    Yasuto Uchida
    Department of Cardiology, Toho University Ohmori Hospital, Tokyo, Japan
    Int Heart J 52:331-7. 2011
    ..NTG caused an increase in either arterial or venous SMBF depending on control endocardial color, wall motion and severity of coronary stenosis...
  19. ncbi request reprint Cardioscopic observation of subendocardial microvessels in patients with coronary artery disease
    Yasuto Uchida
    Department of Cardiology, Toho University Medical Center Ohmori Hospital, Tokyo, Japan
    Int Heart J 52:274-9. 2011
    ..It remains to be elucidated whether and how blood filling is disturbed in other categories of heart disease...
  20. ncbi request reprint Evaluation of myocardial tissue fluid flow by fluorescence cardioscopy in patients with coronary artery disease
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, ChibaKensei Hospital, Chiba, Japan
    Int Heart J 51:153-8. 2010
    ..FC is clinically feasible for evaluation of MTFF disturbance, for evaluation of even emergency coronary interventions, and for guidance of transendocardial angiogenic and myogenic therapies in patients with coronary artery disease...
  21. ncbi request reprint Migration of mononuclear cells expressing β-actin through the adventitia into media and intima in coronary arteriogenesis and venogenesis in ischemic myocardium
    Yasuto Uchida
    Department of Cardiology, Toho University Medical Center, Ohmori Hospital, Tokyo, Japan
    Int Heart J 53:54-63. 2012
    ....
  22. ncbi request reprint Possible role of damaged neoendothelial cells in the genesis of coronary stent thrombus in chronic phase. A dye staining angioscopic study
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Chiba, Japan
    Int Heart J 52:12-6. 2011
    ..05). ST arose from damaged NECs covering the stent struts. NECs may have been damaged due to friction between them and struts due to thin interposed neointima which might have acted as a cushion, resulting in ST...
  23. ncbi request reprint Imaging of subendocardial myocardial blood flow by dye-staining cardioscopy in patients with coronary artery disease
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Toho University Sakira Hospital, Chiba, Japan
    Int Heart J 51:308-11. 2010
    ..It is evident that SMBF could be imaged by DSC. This imaging modality is useful for the evaluation of therapies and accurate guidance of transendocardial therapies of the ischemic myocardium...
  24. ncbi request reprint Molecular imaging of apolipoprotein B-100 in human coronary plaques by color fluorescent angioscopy and microscopy
    Nobuyuki Hiruta
    Department of Pathology, Toho University Sakura Hospital, Chiba, Japan
    Int Heart J 54:68-74. 2013
    ..2) CFA is feasible for imaging of ApoB-100 in human coronary artery wall...
  25. ncbi request reprint β-actin-positive mononuclear cells participate in coronary microvascular medial hyperplasia by migrating through adventitia into media, with special reference to microvessel angina
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, 2 30 17 Narashino dai, Funabashi, Chiba, Japan
    Int Heart J 53:43-53. 2012
    ..MNCs are a vascular progenitor, and migrate out of the adventitia into media, and participate in the etiology of coronary microvascular medial hyperplasia...
  26. ncbi request reprint Imaging of lysophosphatidylcholine in human coronary plaques by color fluorescence angioscopy
    Yasumi Uchida
    Japan Foundation for Cardiovascular Research, Funabashi, Chiba, Japan
    Int Heart J 51:129-33. 2010
    ..This fluorescence color was found to be distributed in a web-like or diffuse configuration by CFM scanning. LPC in the human coronary plaques was successfully visualized by CFA using TB as an indicator...
  27. ncbi request reprint Angioscopic evaluation of stabilizing effects of an antilipemic agent, bezafibrate, on coronary plaques in patients with coronary artery disease: a multicenter prospective study
    Hidefumi Ohsawa
    Cardiovascular Center, Sakura Hospital of Toho University School of Medicine, Narita Red Cross Hospital, Chiba, Japan
    Jpn Heart J 43:319-31. 2002
    ..These results indicate that 6 month administration of bezafibrate stabilizes coronary plaques and that the stabilization is not correlated with angiographic changes...
  28. ncbi request reprint Mechanism of antithrombotic effect of heparin and antithrombin in balloon-injured arteries
    Takanobu Tomaru
    Cardiovascular Center, Toho University Sakura Hospital, Shimoshizu 564 1, Sakura, Chiba 285 8741, Japan
    Life Sci 77:2611-25. 2005
    ..These results indicate that the relatively long antithrombotic effect of these drugs may be due to a local drug effect at the injured artery, as well as the recovery of the anti-thrombogenicity of the injured artery...