Shinichi Tsutsui

Summary

Country: Japan

Publications

  1. ncbi Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu Medical Center, Beppu, Japan
    Oncology 68:398-404. 2005
  2. ncbi Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu Medical Center, 1473 Oaza Uchikamado, Beppu 874 0011, Japan
    Oncol Rep 14:425-31. 2005
  3. ncbi Inactivation of PTEN is associated with a low p27Kip1 protein expression in breast carcinoma
    Shinichi Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Bunkyo, Matsuyama, Japan
    Cancer 104:2048-53. 2005
  4. ncbi Angiopoietin 2 expression in invasive ductal carcinoma of the breast: its relationship to the VEGF expression and microvessel density
    Shinichi Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Matsuyama, Japan
    Breast Cancer Res Treat 98:261-6. 2006
  5. ncbi Prognostic significance of the coexpression of p53 protein and c-erbB2 in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza Uchikamado, Beppu 874 0011, Japan
    Am J Surg 185:165-7. 2003
  6. ncbi A loss of c-kit expression is associated with an advanced stage and poor prognosis in breast cancer
    S Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Japan
    Br J Cancer 94:1874-8. 2006
  7. ncbi Flow cytometric analysis of DNA ploidy in primary, metastatic and recurrent breast cancers
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, Beppu 874 0011, Japan
    Oncol Rep 9:793-9. 2002
  8. ncbi The Akt expression correlates with the VEGF-A and -C expression as well as the microvessel and lymphatic vessel density in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Hiroshima Red Cross and Atomic Bomb Survivors Hospital, Hiroshima 730 8619, Japan
    Oncol Rep 23:621-30. 2010
  9. ncbi Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Matsuyama, Japan
    BMC Cancer 6:187. 2006
  10. ncbi Prognostic significance of the combination of biological parameters in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Surg Today 33:151-4. 2003

Collaborators

Detail Information

Publications27

  1. ncbi Reduced expression of PTEN protein and its prognostic implications in invasive ductal carcinoma of the breast
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu Medical Center, Beppu, Japan
    Oncology 68:398-404. 2005
    ..The aim of this study was to analyze PTEN protein expression in breast cancer and to evaluate the prognostic significance of PTEN protein expression...
  2. ncbi Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu Medical Center, 1473 Oaza Uchikamado, Beppu 874 0011, Japan
    Oncol Rep 14:425-31. 2005
    ..The prognostic significance of MVD was the strongest among these three factors in breast cancer. These findings suggested that the prognostic implications of TAM infiltration are due to the involvement of TAMs in tumor angiogenesis...
  3. ncbi Inactivation of PTEN is associated with a low p27Kip1 protein expression in breast carcinoma
    Shinichi Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Bunkyo, Matsuyama, Japan
    Cancer 104:2048-53. 2005
    ..Recent experimental studies suggested that the cell cycle inhibitor p27Kip1 (p27) is a downstream mediator through which PTEN negatively regulates cell cycle progression...
  4. ncbi Angiopoietin 2 expression in invasive ductal carcinoma of the breast: its relationship to the VEGF expression and microvessel density
    Shinichi Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Matsuyama, Japan
    Breast Cancer Res Treat 98:261-6. 2006
    ..The survival analysis demonstrated a high MVD, which was induced by a high expression of both VEGF and Ang-2, to therefore have a strong prognostic significance in breast cancer...
  5. ncbi Prognostic significance of the coexpression of p53 protein and c-erbB2 in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza Uchikamado, Beppu 874 0011, Japan
    Am J Surg 185:165-7. 2003
    ..The expressions of p53 protein and c-erbB2 have been thoroughly analyzed as prognostic factors for breast cancer. However, the prognostic significance of the coexpression of p53 protein and c-erbB2 remains controversial...
  6. ncbi A loss of c-kit expression is associated with an advanced stage and poor prognosis in breast cancer
    S Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Japan
    Br J Cancer 94:1874-8. 2006
    ..The prognostic implications of the c-kit expression seem to be due to fact that a loss of the c-kit expression is associated with an advanced stage of breast cancer...
  7. ncbi Flow cytometric analysis of DNA ploidy in primary, metastatic and recurrent breast cancers
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, Beppu 874 0011, Japan
    Oncol Rep 9:793-9. 2002
    ..In conclusion, the majority of DNA ploidies are consistent among the primary, synchronous metastatic and recurrent lesions of breast cancer. The existence of aneuploidy itself may also play a prognostic role in breast cancer...
  8. ncbi The Akt expression correlates with the VEGF-A and -C expression as well as the microvessel and lymphatic vessel density in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Hiroshima Red Cross and Atomic Bomb Survivors Hospital, Hiroshima 730 8619, Japan
    Oncol Rep 23:621-30. 2010
    ..The correlation of the Akt expression to the VEGF-A and -C expression as well as MVD and LVD, thus, suggested Akt activation to contribute to both angiogenesis and lymphangiogenesis via VEGF-A and -C expression in breast cancer...
  9. ncbi Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Matsuyama Red Cross Hospital, Matsuyama, Japan
    BMC Cancer 6:187. 2006
    ..The prognostic implication of Bcl-2 protein expression in relation to p27 and p53 protein expressions and MIB-1 counts for breast cancer was also evaluated...
  10. ncbi Prognostic significance of the combination of biological parameters in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Surg Today 33:151-4. 2003
    ..In conclusion, the present study indicated a gradual increase in the prognostic significance as the number of combined biological parameters increased...
  11. ncbi Histological classification of invasive ductal carcinoma and the biological parameters in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Breast Cancer 10:149-52. 2003
    ..CONCLUSION: Abnormalities in the biological parameters listed above were frequently found in the solid-tubular type of invasive ductal carcinoma...
  12. ncbi Prognostic value of the combination of epidermal growth factor receptor and c-erbB-2 in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Surgery 133:219-21. 2003
    ..CONCLUSIONS: Breast cancer with both a positive EGFR and c-erbB-2 expression had the worst prognosis, whereas the prognostic value of c-erbB-2 was stronger than that of EGFR in breast cancer...
  13. ncbi Prognostic value of c-erbB2 expression in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, Beppu, Japan
    J Surg Oncol 79:216-23. 2002
    ....
  14. ncbi DNA aneuploidy in relation to the combination of analysis of estrogen receptor, progesterone receptor, p53 protein and epidermal growth factor receptor in 498 breast cancers
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, Beppu, Japan
    Oncology 63:48-55. 2002
    ....
  15. ncbi Comparison of the immunohistochemical expression of EGFR, c-erbB2 and p53 protein between primary and recurrent breast cancer
    Shinichi Tsutsui
    Shinichi Tsutsui, Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Breast Cancer 9:111-7. 2002
    ....
  16. ncbi Detection of occult cancer cells in peripheral blood and bone marrow by quantitative RT-PCR assay for cytokeratin-7 in breast cancer patients
    Taka-Aki Masuda
    Department of Molecular and Surgical Oncology, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
    Int J Oncol 26:721-30. 2005
    ..QRT-PCR for CK-7 could be a useful and universal method for detecting O.M, and the quantitative detection of CK-7 in P.B. would have a prognostic value as a marker of early recurrence in breast cancer patients with surgery...
  17. ncbi Gastric carcinoma with protein-losing gastroenteropathy: report of a case
    Manabu Yamamoto
    Department of Surgery, Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital, 1 9 6 Senda machi, Naka ku, Hiroshima 730 8619, Japan
    Surg Today 41:125-9. 2011
    ..Gastric cancer with protein-losing gastroenteropathy is extremely rare, but it can easily be diagnosed if the villous or cauliflower-like features are well defined...
  18. ncbi Prognostic implication of p53 protein expression in relation to nuclear pleomorphism and the MIB-1 counts in breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Breast Cancer 11:160-8. 2004
    ....
  19. ncbi Prognostic and predictive value of epidermal growth factor receptor in recurrent breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, Beppu 874-0011, Japan
    Clin Cancer Res 8:3454-60. 2002
    ..In addition, the EGFR expression was suggested to be related to the responses to hormonal therapy and chemotherapy, whereas the EGFR expression had an additional prognostic value that was independent of the treatment response...
  20. ncbi Prognostic value of microvessel density in invasive ductal carcinoma of the breast
    Shinichi Tsutsui
    Department of Breast Surgery, Beppu National Hospital, 1473 Oaza-Uchikamado, Beppu 874-0011, Japan
    Breast Cancer 10:312-9. 2003
    ..CONCLUSION: MVD was found to be an independent prognostic indicator of recurrence and death for breast cancer, and is therefore considered to be a useful factor for selecting high risk patients to receive adjuvant therapies...
  21. ncbi Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer
    Shinichi Tsutsui
    Department of Breast Surgery, National Kyushu Cancer Center, Fukuoka, Japan
    Breast Cancer Res Treat 71:67-75. 2002
    ....
  22. ncbi Subcutaneous gluteal metastasis from gastric cancer: case report and clinicopathologic analysis of 50 Japanese patients
    Kazuhiro Yasuda
    Department of Surgery, Beppu Medical Center, Beppu, Japan
    Int Surg 93:107-10. 2008
    ..However, she died of the disease 9 months after the diagnosis of skin metastasis. We reviewed the cases of 50 Japanese patients with skin metastasis from gastric cancer and analyzed the clinicopathologic features...
  23. ncbi Prognostic re-evaluation of peritoneal lavage cytology in Japanese patients with gastric carcinoma
    Manabu Yamamoto
    Department of Surgery, Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital, 1 9 6, Senda machi, Naka ku, Hiroshima 730 8619, Japan
    Hepatogastroenterology 56:261-5. 2009
    ....
  24. ncbi Risk factors for morbidity and mortality following abdominal surgery in patients on maintenance hemodialysis
    Kazuhiro Yasuda
    Department of Surgery, Beppu Medical Center, Beppu, Japan
    Hepatogastroenterology 54:2282-4. 2007
    ..We conducted the retrospective study to identify risk factors for morbidity and mortality after abdominal surgery in hemodialysis patients...
  25. ncbi Metastatic breast cancer with HER2/neu-positive cells tends to have a morbid prognosis
    Yasunori Emi
    Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Surgery 131:S217-21. 2002
    ..For such patients with metastatic breast cancer, a high-dose anthracycline-containing regimen might be needed...
  26. ncbi [Departmental review of surgical cases during the past 17 years: Esophageal cancers]
    Takeshi Oga
    Fukuoka Igaku Zasshi 93:4-8. 2002
  27. ncbi [Long- and short-term survivors after chemotherapy among patients with advanced or recurrent gastric cancer in our hospital]
    Manabu Yamamoto
    Department of Surgery, Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital
    Gan To Kagaku Ryoho 35:599-602. 2008
    ....