K Tsuchiya

Summary

Country: Japan

Publications

  1. ncbi request reprint Familial amyotrophic lateral sclerosis with posterior column degeneration and basophilic inclusion bodies: a clinical, genetic and pathological study
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Metropolitan Matsuzawa Hospital, Tokyo, Japan
    Clin Neuropathol 20:53-9. 2001
  2. ncbi request reprint Constant involvement of the Betz cells and pyramidal tract in amyotrophic lateral sclerosis with dementia: a clinicopathological study of eight autopsy cases
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo 156 0057, Japan
    Acta Neuropathol 104:249-59. 2002
  3. ncbi request reprint Distribution of cerebral cortical lesions in Pick's disease with Pick bodies: a clinicopathological study of six autopsy cases showing unusual clinical presentations
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo, 156 0057, Japan
    Acta Neuropathol 102:553-71. 2001
  4. ncbi request reprint Parkinson's disease mimicking senile dementia of the Alzheimer type: a clinicopathological study of four autopsy cases
    Kuniaki Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Japan
    Neuropathology 22:77-84. 2002
  5. ncbi request reprint Distribution of basal ganglia lesions in generalized variant of Pick's disease: a clinicopathological study of four autopsy cases
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Japan
    Acta Neuropathol 102:441-8. 2001
  6. ncbi request reprint Distribution of basal ganglia lesions in diffuse neurofibrillary tangles with calcification: a clinicopathological study of five autopsy cases
    K Tsuchiya
    Department of Neuropathology, Tokyo Institute of Psychiatry, Japan
    Acta Neuropathol 103:555-64. 2002
  7. ncbi request reprint Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions
    Kuniaki Tsuchiya
    Department of Laboratory Medicine and Pathology, Metropolitan Matsuzawa Hospital, Tokyo, Japan
    Neuropathology 22:308-16. 2002
  8. ncbi request reprint Alz-50/Gallyas-positive lysosome-like intraneuronal granules in Alzheimer's disease and control brains
    K Ikeda
    Department of Neuropathology, Tokyo Institute of Psychiatry, Japan
    Neurosci Lett 258:113-6. 1998
  9. ncbi request reprint Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/alpha-synuclein
    T Arai
    Department of Neuropathology, Institute of Psychiatry, Tokyo, Japan
    Neurosci Lett 259:83-6. 1999
  10. ncbi request reprint Substantia nigra in progressive supranuclear palsy, corticobasal degeneration, and parkinsonism-dementia complex of Guam: specific pathological features
    K Oyanagi
    Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Fuchu, Japan
    J Neuropathol Exp Neurol 60:393-402. 2001

Detail Information

Publications58

  1. ncbi request reprint Familial amyotrophic lateral sclerosis with posterior column degeneration and basophilic inclusion bodies: a clinical, genetic and pathological study
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Metropolitan Matsuzawa Hospital, Tokyo, Japan
    Clin Neuropathol 20:53-9. 2001
    ..Based on these clinical, genetic and pathological findings with a review of the literature, we concluded that our case was the first reported case of FALS with posterior column involvement and basophilic inclusion bodies...
  2. ncbi request reprint Constant involvement of the Betz cells and pyramidal tract in amyotrophic lateral sclerosis with dementia: a clinicopathological study of eight autopsy cases
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo 156 0057, Japan
    Acta Neuropathol 104:249-59. 2002
    ..Furthermore, we believe that this study will also contribute to the elucidation of the nosological status of ALS with dementia...
  3. ncbi request reprint Distribution of cerebral cortical lesions in Pick's disease with Pick bodies: a clinicopathological study of six autopsy cases showing unusual clinical presentations
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, 2 1 1 Kamikitazawa, Setagaya Ku, Tokyo, 156 0057, Japan
    Acta Neuropathol 102:553-71. 2001
    ....
  4. ncbi request reprint Parkinson's disease mimicking senile dementia of the Alzheimer type: a clinicopathological study of four autopsy cases
    Kuniaki Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Japan
    Neuropathology 22:77-84. 2002
    ..Furthermore, we postulate that the clinical features of PD are more widespread than previously believed...
  5. ncbi request reprint Distribution of basal ganglia lesions in generalized variant of Pick's disease: a clinicopathological study of four autopsy cases
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Japan
    Acta Neuropathol 102:441-8. 2001
    ..These clinicopathological findings may contribute not only to the elucidation of clinicopathological hallmarks, but also to the progress of neuroimaging, in the generalized variant of Pick's disease...
  6. ncbi request reprint Distribution of basal ganglia lesions in diffuse neurofibrillary tangles with calcification: a clinicopathological study of five autopsy cases
    K Tsuchiya
    Department of Neuropathology, Tokyo Institute of Psychiatry, Japan
    Acta Neuropathol 103:555-64. 2002
    ..These clinicopathological findings may contribute to the elucidation of the clinicopathological hallmarks in this disorder...
  7. ncbi request reprint Sporadic amyotrophic lateral sclerosis with circumscribed temporal atrophy: a report of an autopsy case without dementia and with ubiquitinated intraneuronal inclusions
    Kuniaki Tsuchiya
    Department of Laboratory Medicine and Pathology, Metropolitan Matsuzawa Hospital, Tokyo, Japan
    Neuropathology 22:308-16. 2002
    ..We also note the possibility that there is a forme fruste of ALS with dementia showing no overt dementia clinically...
  8. ncbi request reprint Alz-50/Gallyas-positive lysosome-like intraneuronal granules in Alzheimer's disease and control brains
    K Ikeda
    Department of Neuropathology, Tokyo Institute of Psychiatry, Japan
    Neurosci Lett 258:113-6. 1998
    ..The Alz-50 immunoreactive granules showed ultrastructural features similar to those of lysosomes or lipofuscin. These findings suggest that denatured tau might be degraded in lysosomes...
  9. ncbi request reprint Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/alpha-synuclein
    T Arai
    Department of Neuropathology, Institute of Psychiatry, Tokyo, Japan
    Neurosci Lett 259:83-6. 1999
    ....
  10. ncbi request reprint Substantia nigra in progressive supranuclear palsy, corticobasal degeneration, and parkinsonism-dementia complex of Guam: specific pathological features
    K Oyanagi
    Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Fuchu, Japan
    J Neuropathol Exp Neurol 60:393-402. 2001
    ..It is possible to differentiate between PSP and CBD by the occurrence of many pretangles in CBD, but some similarities between these 2 diseases indicate the existence of common pathological mechanisms...
  11. ncbi request reprint New insights into the thrombopoietic status of patients on dialysis through the evaluation of megakaryocytopoiesis in bone marrow and of endogenous thrombopoietin levels
    M Ando
    Division of Nephrology, Tokyo Metropolitan Geriatric Medical Center, Tokyo, Japan
    Blood 97:915-21. 2001
    ..Elevation of serum TPO may in part serve as an aid to erythropoiesis in dialysis patients...
  12. ncbi request reprint Argyrophilic grain disease mimicking temporal Pick's disease: a clinical, radiological, and pathological study of an autopsy case with a clinical course of 15 years
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Japan
    Acta Neuropathol 102:195-9. 2001
    ..This report may contribute to the elucidation of the clinicopathological hallmarks of AGD...
  13. ncbi request reprint Atypical amyotrophic lateral sclerosis with dementia mimicking frontal Pick's disease: a report of an autopsy case with a clinical course of 15 years
    K Tsuchiya
    Department of Laboratory Medicine and Pathology, Tokyo Metropolitan Matsuzawa Hospital, Japan
    Acta Neuropathol 101:625-30. 2001
    ..We also note the possibility that motor neuron disease-inclusion dementia with a long clinical course may develop into ALS in the final stage of the illness...
  14. ncbi request reprint Atypical late-onset dementia characterized by limbic degeneration with coiled bodies and argyrophilic threads
    K Oshima
    Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan
    Clin Neuropathol 22:296-303. 2003
    ..Further study is needed to determine whether the present case could be classified as an atypical case of these diseases or represents a new entity...
  15. ncbi request reprint Neurons containing Alz-50-immunoreactive granules around the cerebral infarction: evidence for the lysosomal degradation of altered tau in human brain?
    K Ikeda
    Department of Neuropathology, Tokyo Institute of Psychiatry, 2 1 8, Kamikitazawa, Setagaya Ku, Tokyo, Japan
    Neurosci Lett 284:187-9. 2000
    ..Alz-50-positive granules were more prominent in fresh infarction than in old infarction. After undergoing degradation and modification, altered tau might remain, at least partially, in secondary lysosomes...
  16. ncbi request reprint Intracellular processing of aggregated tau differs between corticobasal degeneration and progressive supranuclear palsy
    T Arai
    Department of Neuropathology, Tokyo Institute of Psychiatry, Japan
    Neuroreport 12:935-8. 2001
    ..Such biochemical differences may be related to the neuropathological features of these diseases...
  17. ncbi request reprint A potent antiviral effect on hepatitis C viral dynamics in serum and peripheral blood mononuclear cells during combination therapy with high-dose daily interferon alfa plus ribavirin and intravenous twice-daily treatment with interferon beta
    Y Asahina
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    Hepatology 34:377-84. 2001
    ..Taken together, our data on HCV dynamics provide molecular insight into utilization of combination or twice-daily dosing regimens to increase rates of sustained viral eradication of HCV...
  18. pmc Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy
    M Honda
    Sleep Disorders Research Project, Tokyo Institute of Psychiatry, 2 1 8 Kamikitazawa, Setagaya Ku, Tokyo 156 8585, Japan
    Neurology 73:511-7. 2009
    ..To test this hypothesis, we evaluated the remaining hypocretin cells in human narcolepsy brains for the presence of aggregated protein inclusions, gliosis, and inflammation...
  19. ncbi request reprint Different conformation of neuronal tau deposits distinguished by double immunofluorescence with AT8 and thiazin red combined with Gallyas method
    T Uchihara
    Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Japan
    Acta Neuropathol 102:462-6. 2001
    ....
  20. doi request reprint Usefulness of measuring reticulocyte hemoglobin equivalent in the management of haemodialysis patients with iron deficiency
    N Miwa
    Department of Blood Purification, Tokyo Women s Medical University, Tokyo, Japan
    Int J Lab Hematol 32:248-55. 2010
    ..RET-He is a new parameter, equivalent value to CHr, and is easily measurable on the widely spread and popular blood cell counter and is a sensitive and specific marker of iron status in dialysis patients...
  21. ncbi request reprint [An autopsied case of presenile dementia with tangles]
    K Niizato
    Department of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, 2-1-1 Kamikitazawa, Setagaya-ku, Tokyo 156-0057, Japan
    No To Shinkei 53:659-64. 2001
    ..In our case, the onset was presenile and we could exclude any other diseases, that usually present with NFT, and to our knowledge, this is the first report of a presenile dementia with tangles...
  22. ncbi request reprint MRI of influenza encephalopathy in children: value of diffusion-weighted imaging
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, Tokyo, Japan
    J Comput Assist Tomogr 24:303-7. 2000
    ..Our purpose was to describe the MR findings of influenza encephalopathy and assess the value of diffusion-weighted imaging for its diagnosis...
  23. doi request reprint New-onset microalbuminuria following allogeneic myeloablative SCT is a sign of near-term decrease in renal function
    T Morito
    Department of Medicine, Division of Nephrology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan
    Bone Marrow Transplant 48:972-6. 2013
    ..3 (1.2-140)). In conclusion, de novo microalbuminuria following conditioning therapy is a warning of near-term loss of renal function...
  24. ncbi request reprint Japanese encephalitis - serial CT findings and neuropathology in an autopsy case
    Z Kobayashi
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Clin Neuropathol 28:422-9. 2009
    ..We discussed for the first time the correlation of CT and neuropathological findings in a patient with Japanese encephalitis...
  25. ncbi request reprint Diffusion-weighted MR imaging of Carmofur-induced leukoencephalopathy
    A Fujikawa
    Department of Radiology, Kyorin University, 6 20 2, Shinkawa, Mitaka, Tokyo, 181 8611, Japan
    Eur Radiol 11:2602-6. 2001
    ..Our results suggest that diffusion-weighted MR imaging may be useful to differentiate carmofur-induced leukoencephalopathy from age-related periventricular hyperintensity...
  26. ncbi request reprint Appearance of tau-2 immunoreactivity in glial cells in human brain with cerebral infarction
    T Uchihara
    Department of Neuropathology, Tokyo Metropolitan Institute for Neuroscience, 2 6 Musashi dai, Fuchu, Tokyo, 183 8526, Japan
    Neurosci Lett 286:99-102. 2000
    ..Lack of argyrophilia in any of these tau-immunoreactive cells distinguishes them from tau-immunoreactive structures seen in various neurodegenerative disorders...
  27. doi request reprint Noninvasive estimation of fibrosis progression overtime using the FIB-4 index in chronic hepatitis C
    N Tamaki
    Division of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Viral Hepat 20:72-6. 2013
    ..4 (P < 0.001). In conclusion, measurement of the time-course changes in the FIB-4 index is useful for the noninvasive and real-time estimation of the progression in liver fibrosis...
  28. ncbi request reprint Preliminary evaluation of volume-rendered three-dimensional display of time-of-flight MR angiography in the diagnosis of intracranial aneurysms
    K Tsuchiya
    Department of Radiology, Kyorin University, Tokyo, Japan
    Neuroradiology 43:633-6. 2001
    ..3D volume-rendered MRA can be effectively added to conventional imaging techniques for diagnosis of intracranial aneurysms...
  29. ncbi request reprint Visualization of cervical nerve roots and their distal nerve fibers by diffusion-weighted scanning using parallel imaging
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Acta Radiol 47:599-602. 2006
    ..To report a technique developed for visualizing cervical nerve roots and distal nerve fibers using diffusion-weighted magnetic resonance imaging employing parallel imaging...
  30. ncbi request reprint Corticobasal degeneration presenting with nonfluent primary progressive aphasia: a clinicopathological study
    M Mimura
    Department of Neuropsychiatry, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, 142 8666, Tokyo, Japan
    J Neurol Sci 183:19-26. 2001
    ..The clinical manifestations in CBD are diverse, and primary progressive nonfluent aphasia should be considered as an initial symptom of CBD. Neuropathological examination of such patients should include cytoskeletal abnormality studies...
  31. ncbi request reprint Mutational analysis within the 3' region of the PKD1 gene in Japanese families
    K Tsuchiya
    Department of Medicine IV, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku ku, 162 8666, Tokyo, Japan
    Mutat Res 458:77-84. 2001
    ..These were novel mutations, except for R3752W, and three of them were identified in more than two families. Mutation analysis of the PKD1 gene in the Japanese population is being reported for the first time...
  32. ncbi request reprint Diffusion-weighted MR imaging in multiple sclerosis: comparison with contrast-enhanced study
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Eur J Radiol 31:165-9. 1999
    ..To assess the utility of cerebral diffusion-weighted MR imaging in the diagnosis of multiple sclerosis (MS) in comparison with contrast-enhanced T1-weighted imaging...
  33. ncbi request reprint Volume-rendered 3D display of MR angiograms in the diagnosis of cerebral arteriovenous malformations
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, Shinkawa, Mitaka, Tokyo, Japan
    Acta Radiol 44:675-9. 2003
    ..To determine whether application of a volume-rendered display of 3D time-of-flight (TOF) MR angiography could assist the diagnosis of cerebral arteriovenous malformations (AVMs)...
  34. ncbi request reprint Content of reticulocyte hemoglobin is a reliable tool for determining iron deficiency in dialysis patients
    K Tsuchiya
    Department of Medicine IV, Tokyo Women s Medical University, Tokyo, Japan
    Clin Nephrol 59:115-23. 2003
    ..Iron status of the patients can be determined from the recently available measurement of content of reticulocyte hemoglobin (CHr)...
  35. ncbi request reprint A new MRI technique for demonstrating the surface of the brain together with the cortical veins
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan
    Neuroradiology 41:425-7. 1999
    ..This simple technique is useful for demonstrating brain surface structures, especially in patients from whom one plans to excise a lesion...
  36. ncbi request reprint Developmental expression of maf-1 messenger ribonucleic acids in rat kidney by in situ hybridization histochemistry
    J Imaki
    Department of Anatomy, Nippon Medical School, Tokyo, Japan
    Biochem Biophys Res Commun 272:777-82. 2000
    ..These findings suggest that the expression of maf-1 gene may be involved in embryological development and/or differentiation of the kidney...
  37. doi request reprint MR imaging of IgG4-related disease in the head and neck and brain
    K Toyoda
    Department of Radiology, Teikyo University School of Medicine, Tokyo, Japan
    AJNR Am J Neuroradiol 33:2136-9. 2012
    ....
  38. ncbi request reprint Reduced expression of Toll-like receptor 4 contributes to impaired cytokine response of monocytes in uremic patients
    M Ando
    Department of Nephrology, Tokyo Metropolitan Komagome Hospital, Bunkyo ku, Tokyo, Japan
    Kidney Int 70:358-62. 2006
    ..Abnormal TLR4 expression by monocytes may play a role in the susceptibility of such patients to bacterial infections...
  39. ncbi request reprint Diffusion-weighted MRI of subdural and epidural empyemas
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, 181 8611, Tokyo, Japan
    Neuroradiology 45:220-3. 2003
    ..DWI may be an adjunct to conventional sequences for differentiating between subdural and epidural empyemas...
  40. ncbi request reprint Pharmacokinetics and enhanced PKR response in patients with chronic hepatitis C treated with pegylated interferon alpha-2b and ribavirin
    Y Asahina
    Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan
    J Viral Hepat 14:396-403. 2007
    ..The concentrations of both ribavirin and PEG-IFN alpha-2b were not associated with viral response and PKR expression...
  41. ncbi request reprint Optimal treatment strategy for patients with paroxysmal atrial fibrillation: J-RHYTHM Study
    Satoshi Ogawa
    Department of Cardiology, Keio University, Tokyo, Japan
    Circ J 73:242-8. 2009
    ..However, mortality and cardiovascular morbidity were not affected by the treatment strategy (umin-CTR No. C000000106)...
  42. ncbi request reprint Dementia with Lewy bodies showing advanced Lewy pathology but minimal Alzheimer pathology--Lewy pathology causes neuronal loss inducing progressive dementia
    H Uchikado
    Department of Psychiatry, Yokohama City University School of Medicine, Yokohama, Japan
    Clin Neuropathol 21:269-77. 2002
    ..Consequently, the present case was pathologically diagnosed as having DLB of the neocortical type, pure form. In the present study, we suggest that Lewy pathology in the cerebral cortex could be responsible for progressive dementia...
  43. pmc Sympathetic cardiac denervation in Parkinson's disease and pure autonomic failure but not in multiple system atrophy
    S Orimo
    J Neurol Neurosurg Psychiatry 73:776-7. 2002
  44. pmc Atypical cause of hibernating myocardium due to complex cardiovascular lesions associated with Takayasu's arteritis
    M Nakajima
    Department of Cardiovascular Surgery, Yamanashi Central Hospital, 1 1 1 Fujimi, Kofu City, Yamanashi, Japan 400 0027
    Heart 90:e43. 2004
    ....
  45. ncbi request reprint A molecular phylogenetic framework for the Ryukyu endemic rodents Tokudaia osimensis and Diplothrix legata
    H Suzuki
    Laboratory of Ecology and Genetics, Hokkaido University, Sapporo, 060 0810, Japan
    Mol Phylogenet Evol 15:15-24. 2000
    ..legata established its lineage at least by the beginning of the Pleistocene era. It is thus evident that the Okinawa area preserves rare indigenous species with various levels of genetic endemicity...
  46. ncbi request reprint Phylogeographic origin of Hokkaido house mice (Mus musculus) as indicated by genetic markers with maternal, paternal and biparental inheritance
    M Terashima
    1Laboratory of Ecology and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Kita ku, Sapporo 060 0810, Japan
    Heredity (Edinb) 96:128-38. 2006
    ..There are, however, alternative interpretations, including genetic admixture between MUS arriving by a southern route and CAS from a northern route...
  47. ncbi request reprint Two cases of atypical melanocytic lesions in recessive dystrophic epidermolysis bullosa infants
    K Natsuga
    Department of Dermatology, Hokkaido University Graduate School of Medicine, and Department of Dermatology, Sapporo City General Hospital, Sapporo, Japan
    Clin Exp Dermatol 30:636-9. 2005
    ..AtML may easily be misdiagnosed as malignant melanoma and, even in infant patients with RDEB, this should be included as one of the differential diagnosis of pigmented lesions...
  48. ncbi request reprint Differentiation between solitary brain metastasis and high-grade glioma by diffusion tensor imaging
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, 6 20 2, Shinkawa, Mitaka, Tokyo 181 8611, Japan
    Br J Radiol 78:533-7. 2005
    ..Although FA values are not helpful in differentiating between the two groups, visual differences in FA values can allow the differentiation. Displacement of white-matter fibres is another finding suggestive of metastasis...
  49. ncbi request reprint A new inbred strain JF1 established from Japanese fancy mouse carrying the classic piebald allele
    T Koide
    Mammalian Genetics Laboratory, National Institute of Genetics, Shizuoka ken, Japan
    Mamm Genome 9:15-9. 1998
    ..The clarified genotypes of JF1 for coat color are "aa BB CC DD ss"...
  50. ncbi request reprint Diffuse neurofibrillary tangles with calcification (a form of dementia): X-ray spectrometric evidence of lead accumulation in calcified regions
    T Haraguchi
    Department of Neuropsychiatry, Okayama University Medical School, 2-5-1 Shikata-cho, Okayama, Japan
    Neuroreport 12:1257-60. 2001
    ..The implications and possible significance of the lead accumulation in DNTC brains are discussed...
  51. ncbi request reprint [An autopsy case of pure autonomic failure with pathological features of Parkinson's disease]
    H Miura
    Department of 5th Internal Medicine, Tokyo Medical University
    Rinsho Shinkeigaku 41:40-4. 2001
    ..This is a rare and important report on a patient with PAF who satisfied the strict clinical criteria on PAF reported in 1996, and showed neuropathological findings, consistent with Parkinson's disease...
  52. ncbi request reprint Lead content of brain tissue in diffuse neurofibrillary tangles with calcification (DNTC): the possibility of lead neurotoxicity
    T Haraguchi
    Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan
    Neuroreport 12:3887-90. 2001
    ..Although it remains unclear how these findings are related to the formation of NFTs, they suggest that Pb neurotoxicity may be involved in the pathogenesis of DNTC...
  53. ncbi request reprint Combination of HLA-A and HLA class II alleles controls the susceptibility to rheumatoid arthritis
    K Tsuchiya
    Department of Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
    Tissue Antigens 58:395-401. 2001
    ..Our results suggested the possibility that the susceptibility to RA is controlled by the interaction of HLA-A and DRBl genes or by that of HLA-A and DPBl genes in different patient subgroups...
  54. ncbi request reprint Diffusion-weighted MRI of the cervical spinal cord using a single-shot fast spin-echo technique: findings in normal subjects and in myelomalacia
    K Tsuchiya
    Department of Radiology, Kyorin University School of Medicine, 6 20 2 Shinkawa, Mitaka, 181 8611 Tokyo, Japan
    Neuroradiology 45:90-4. 2003
    ..30+/-0.38x10(-3) mm(2)/s) were significantly higher than those of normal volunteers (2.26+/-0.08x10(-3) mm(2)/s). Increased diffusion in areas of cervical myelomalacia, suggesting irreversible damage, can be detected using this technique...
  55. ncbi request reprint Progressive supranuclear palsy presenting with primary progressive aphasia--clinicopathological report of an autopsy case
    A Mochizuki
    Department of Neurology, Institute of Clinical Medicine, University of Tsukuba, 1 1 1 Tennodai, 305 8575, Ibaraki, Japan
    Acta Neuropathol 105:610-4. 2003
    ..Although focal cortical symptoms in PSP are rare or absent, we should keep in mind the possibility of atypical PSP in which cortical pathology is predominant, particularly in the frontal lobe, and could result in PPA...
  56. ncbi request reprint Marked asymmetry of putaminal pathology in an MSA-P patient with Pisa syndrome
    I Hozumi
    Department of Neurology and Geriatrics, Gifu University, School of Medicine, Gifu, Japan
    Mov Disord 19:470-2. 2004
    ..The pathophysiological mechanism underlying forms of axial dystonia remains to be elucidated. We report here the histopathological findings of a multiple system atrophy of parkinsonian predominance (MSA-P) patient with Pisa syndrome...
  57. ncbi request reprint PCR-based identification and characterization of Burkholderia cepacia complex bacteria from clinical and environmental sources
    S T Seo
    Division of Microbiology, National Institute for Agro Environmental Sciences NIAES, Tsukuba 305 8604, Japan
    Lett Appl Microbiol 39:413-9. 2004
    ..To study the genotypic identification and characterization of the 119 Burkholderia cepacia complex (Bcc) strains recovered from clinical and environmental sources in Japan and Thailand...
  58. pmc Chronic Japanese schistosomiasis and hepatocellular carcinoma: ten years of follow-up in Yamanashi Prefecture, Japan
    F Iida
    Yamanashi Kosei Hospital, Kofu City, Japan
    Bull World Health Organ 77:573-81. 1999
    ..The role of HBV infection in the development of hepatoma in schistosomiasis patients was not confirmed after an assay for HCVAb was included in the study...