Hiroaki Sakurai


Affiliation: Toyama Medical and Pharmaceutical University
Country: Japan


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    Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, et al. Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J Biol Chem. 2003;278:36916-23 pubmed
  2. request reprint
    Sakurai H, Singhirunnusorn P, Shimotabira E, Chino A, Suzuki S, Koizumi K, et al. TAK1-mediated transcriptional activation of CD28-responsive element and AP-1-binding site within the IL-2 promoter in Jurkat T cells. FEBS Lett. 2005;579:6641-6 pubmed
    ..These results indicate that TAK1 plays a critical role in T cell activation by controlling production of IL-2. ..