Affiliation: Tottori University
- Prostatic stromal sarcoma: case report and review of the literatureMari Osaki
Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine, Tottori University, Yonago National Hospital, Yonago and Miyagawa Clinic, Tottori, Japan
Pathol Int 53:407-11. 2003..The tumor was diagnosed as prostatic stromal sarcoma (PSS) showing epithelioid differentiation and of a progesterone-dependent nature. Possible favorable nature of the PSS might be expected after complete resection...
- Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45Mitsuhiko Osaki
Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine, Tottori University, 86 NIshi cho, Yonago, 683 8503 Tottori, Japan
J Cancer Res Clin Oncol 130:8-14. 2004..We concluded that: 1) the PI3K-Akt pathway plays an important role in preventing Fas-mediated apoptosis; and 2) a PI3 K inhibitor, such as LY294002, might be a useful anti-tumoral agent for gastric carcinoma...
- Expression of RUNX3 protein in human gastric mucosa, intestinal metaplasia and carcinomaM Osaki
Tottori University, Yonago, Japan
Eur J Clin Invest 34:605-12. 2004..Human runt-related transcription factor gene 3 (RUNX3) is considered as a possible candidate of tumour suppressor gene in human gastric carcinoma...
- MAD1 (mitotic arrest deficiency 1) is a candidate for a tumor suppressor gene in human stomachMitsuhiko Osaki
Division of Molecular Genetics and Biofunction, Department of Biomedical Science, Graduate School of Medicine, Tottori University, 86, Nishi cho, Yonago 683 8503, Japan
Virchows Arch 451:771-9. 2007..Taken together, our findings suggest that the MAD1 gene could be a candidate tumor suppressor gene and that down-regulation of MAD1 expression contribute to tumorigenesis in human stomach...
- Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell linesAmi Takeda
Division of Organ Pathology, Department of Microbiology and Pathology, Graduate School of Medicine, Tottori University, Yonago, Japan
Pancreas 28:353-8. 2004....
- Anti-Fas antibody-induced apoptosis and its signal transduction in human gastric carcinoma cell linesKeiko Adachi
Division of Organ Pathology, Department of Microbiology and Pathology, Faculty of Medicine, Tottori University, 86 NIshi cho, Yonago, Tottori 683 8503, Japan
Int J Oncol 23:713-9. 2003..These findings suggest that anti-Fas antibody induced apoptosis through the type II signaling pathway in the human gastric carcinoma cell lines, MKN-45 and KATO-III...