Hisataka ShojiSummaryAffiliation: Toray Industries Country: Japan Publications
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Publications
Extracorporeal endotoxin removal for the treatment of sepsis: endotoxin adsorption cartridge (Toraymyxin)Hisataka Shoji
Division of Planning and Science, Department of Blood Purification Medical Devices, Toray Medical Co, Tokyo, Japan
Ther Apher Dial 7:108-14. 2003..Further studies are now ongoing to establish Toraymyxin treatment as one of the options to treat sepsis and septic shock patients and to clarify the mechanisms involved in this therapy...
Changes in plasma interleukin-18 by direct hemoperfusion with polymyxin B-immobilized fiber in patients with septic shockTsukasa Nakamura
Department of Medicine, Shinmatsudo Central General Hospital, Chiba, Tokyo, Japan
Blood Purif 23:417-20. 2005..CONCLUSIONS: IL-18 may be associated with the severity of septic shock, and PMX-F treatment is effective in reducing the IL-18 level in patients with septic shock...
Effect over time of endotoxin adsorption therapy in sepsisTakuya Ueno
Department of Surgery, Kitasato University School of Medicine, Kanagawa, Japan
Ther Apher Dial 9:128-36. 2005....
Effect of polymyxin B-immobilized fiber on blood metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 levels in acute respiratory distress syndrome patientsTsukasa Nakamura
Department of Medicine, Shinmatsudo Central General Hospital, Chiba, Japan
Blood Purif 22:256-60. 2004..01, TIMP-1 220.6 +/- 30.5 ng/ml, p < 0.01). CONCLUSION: These data suggest that MMP-9 and TIMP-1 may play a role in the pathogenesis of ARDS and that PMX-F treatment ameliorated increased MMP-9 and TIMP-1 levels in ARDS patients...
Effects of hemoperfusion on serum cardiac troponin T concentrations using polymyxin B-immobilized fibers in septic patients undergoing hemodialysisTsukasa Nakamura
Department of Medicine, Misato Junshin Hospital, Saitama, Japan
ASAIO J 48:41-4. 2002..PMX-F is effective in reducing myocardial damage, in part, due to reducing plasma endotoxin levels...
Endotoxin adsorption by polymyxin B immobilized fiber column in patients with systemic inflammatory response syndrome: the Japanese experienceTakashi Sato
Kidney Center, Koga Hospital, Kurume, Fukuoka Japan
Ther Apher Dial 7:252-8. 2003..Further studies are needed to clarify the mechanisms of PMX treatment and to strengthen the scientific basis of this treatment...
Hemoperfusion with polymyxin B-immobilized fiber in septic patients with methicillin-resistant Staphylococcus aureus-associated glomerulonephritisTsukasa Nakamura
Department of Medicine, Misato Junshin Hospital, Saitama, Japan
Nephron Clin Pract 94:c33-9. 2003..CONCLUSION: PMX-F treatment may be effective in reducing urinary protein and urinary podocyte excretion in septic patients with MRSA-associated glomerulonephritis...
Hemoperfusion with polymyxin B immobilized fibers for urinary albumin excretion in septic patients with traumaTsukasa Nakamura
Department of Medicine, Misato Junshin Hospital, Saitama, Japan
ASAIO J 48:244-8. 2002..Neither MACR nor plasma endotoxin levels were affected by conventional treatment, however. In summary, trauma patients with sepsis appear to show increased MACR, and PMX-F therapy may be effective for attenuating the increase in MACR...
Polymyxin B-immobilized fiber hemoperfusion with the PMX-05R column in elderly patients suffering from septic shockTsukasa Nakamura
Department of Medicine, Shinmatsudo Central General Hospital, Chiba, Japan
Am J Med Sci 334:244-7. 2007..The aim of the present study was to determine whether PMX-F treatment with the PMX-05R column is effective in elderly patients with septic shock...
Removal of endotoxin in blood by polymyxin B immobilized polystyrene-derivative fiberKazuo Teramoto
Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa, Japan
Ther Apher 6:103-8. 2002..The adsorption of endotoxin was confirmed by desorption of LPS from PMX-F as well. PMX-F adsorbed serum amyloid protein A besides LPS, but neither C-reactive protein nor low-density lipoprotein. The adsorbing property of heparin was low...
