K Maeda

Summary

Affiliation: Toranomon Hospital
Country: Japan

Publications

  1. ncbi request reprint A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    H Okamoto
    Biological Pharmacological Research Laboratories, Central Pharmaceutical Research Institute, JT Inc, Takatsuki, Osaka, Japan
    Nature 406:203-7. 2000
  2. ncbi request reprint bis(2-(Acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, and S-(2-(acylamino)phenyl) alkanethioates as novel inhibitors of cholesteryl ester transfer protein
    H Shinkai
    Central Pharmaceutical Research Institute, JT Inc, 1 1 Murasaki cho, Takatsuki, Osaka 569 1125, Japan
    J Med Chem 43:3566-72. 2000
  3. ncbi request reprint Molecular modelling and conformational analysis of novel glycoprotein (Gp) IIb/IIIa antagonists. Molecular orbital calculation and the condensed heterocyclic derivatives
    S Ono
    Exploratory Reseach II, Drug Discovery Laboratories, Welfide Corporation, 2 25 1 Shodai Ohtani, Hirakata, 573 1153, Osaka, Japan
    Eur J Med Chem 35:577-92. 2000

Collaborators

  • N Nakamura
  • S Ono
  • H Shinkai
  • H Okamoto
  • T Yamasaki
  • F Yonemori
  • K Wakitani
  • I Uchida
  • T Minowa

Detail Information

Publications3

  1. ncbi request reprint A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    H Okamoto
    Biological Pharmacological Research Laboratories, Central Pharmaceutical Research Institute, JT Inc, Takatsuki, Osaka, Japan
    Nature 406:203-7. 2000
    ..Our findings indicate that CETP may be atherogenic in vivo and that JTT-705 may be a potential anti-atherogenic drug...
  2. ncbi request reprint bis(2-(Acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, and S-(2-(acylamino)phenyl) alkanethioates as novel inhibitors of cholesteryl ester transfer protein
    H Shinkai
    Central Pharmaceutical Research Institute, JT Inc, 1 1 Murasaki cho, Takatsuki, Osaka 569 1125, Japan
    J Med Chem 43:3566-72. 2000
    ..It increased the plasma HDL cholesterol level by 27% and 54%, respectively, when given at oral doses of 30 or 100 mg/kg once a day for 3 days to male Japanese white rabbits...
  3. ncbi request reprint Molecular modelling and conformational analysis of novel glycoprotein (Gp) IIb/IIIa antagonists. Molecular orbital calculation and the condensed heterocyclic derivatives
    S Ono
    Exploratory Reseach II, Drug Discovery Laboratories, Welfide Corporation, 2 25 1 Shodai Ohtani, Hirakata, 573 1153, Osaka, Japan
    Eur J Med Chem 35:577-92. 2000
    ..Molecular orbital calculation studies suggested the presence of a preferred spatial orientation between the amidine and the carboxylic acid...