Research Topics
| K MaedaSummaryAffiliation: Toranomon Hospital Country: Japan Publications
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Detail Information
Publications
A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbitsH Okamoto
Biological Pharmacological Research Laboratories, Central Pharmaceutical Research Institute, JT Inc, Takatsuki, Osaka, Japan
Nature 406:203-7. 2000..Our findings indicate that CETP may be atherogenic in vivo and that JTT-705 may be a potential anti-atherogenic drug...- bis(2-(Acylamino)phenyl) disulfides, 2-(acylamino)benzenethiols, and S-(2-(acylamino)phenyl) alkanethioates as novel inhibitors of cholesteryl ester transfer proteinH Shinkai
Central Pharmaceutical Research Institute, JT Inc, 1 1 Murasaki cho, Takatsuki, Osaka 569 1125, Japan
J Med Chem 43:3566-72. 2000..It increased the plasma HDL cholesterol level by 27% and 54%, respectively, when given at oral doses of 30 or 100 mg/kg once a day for 3 days to male Japanese white rabbits... - Molecular modelling and conformational analysis of novel glycoprotein (Gp) IIb/IIIa antagonists. Molecular orbital calculation and the condensed heterocyclic derivativesS Ono
Exploratory Reseach II, Drug Discovery Laboratories, Welfide Corporation, 2 25 1 Shodai Ohtani, Hirakata, 573 1153, Osaka, Japan
Eur J Med Chem 35:577-92. 2000..Molecular orbital calculation studies suggested the presence of a preferred spatial orientation between the amidine and the carboxylic acid...