Keisuke Miki

Summary

Affiliation: Toneyama National Hospital
Country: Japan

Publications

  1. doi request reprint Effects of ghrelin treatment on exertional dyspnea in COPD: an exploratory analysis
    Keisuke Miki
    Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, 560 8552, Japan
    J Physiol Sci 65:277-84. 2015
  2. doi request reprint Exertional acidotic responses in idiopathic pulmonary fibrosis: the mechanisms of exertional dyspnea
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respir Physiol Neurobiol 185:653-8. 2013
  3. pmc Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Japan
    PLoS ONE 7:e35708. 2012
  4. doi request reprint Effects of oxygen on exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 17:149-54. 2012
  5. doi request reprint Exertional dyspnea-related acidotic and sympathetic responses in patients with sequelae of pulmonary tuberculosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    J Physiol Sci 60:187-93. 2010
  6. doi request reprint Acidosis and raised norepinephrine levels are associated with exercise dyspnoea in idiopathic pulmonary fibrosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 14:1020-6. 2009
  7. ncbi request reprint The degree of exercise hypoxemia reflects pulmonary artery pressure during early exercise in chronic obstructive pulmonary disease patients
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Clin Physiol Funct Imaging 28:64-9. 2008
  8. pmc Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    BMC Pulm Med 13:37. 2013
  9. pmc Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients
    Kenji Yoshimura
    Department of Respiratory Medicine, Toneyama National Hospital, Osaka, Japan
    Int J Chron Obstruct Pulmon Dis 7:109-17. 2012
  10. doi request reprint Identification of three exercise-induced mortality risk factors in patients with COPD
    Kenji Yoshimura
    Department of Respiratory Medicine, National Hospital Organization Toneyama Hospital, Toyonaka City, Osaka, Japan
    COPD 11:615-26. 2014

Collaborators

Detail Information

Publications15

  1. doi request reprint Effects of ghrelin treatment on exertional dyspnea in COPD: an exploratory analysis
    Keisuke Miki
    Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, 560 8552, Japan
    J Physiol Sci 65:277-84. 2015
    ..049) was achieved. In conclusion, underweight COPD patients benefitted from ghrelin treatment in terms of shifts to the early exercise phase of the dyspnea break-point during a standardized exercise program. ..
  2. doi request reprint Exertional acidotic responses in idiopathic pulmonary fibrosis: the mechanisms of exertional dyspnea
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respir Physiol Neurobiol 185:653-8. 2013
    ..Regardless of breathing CA or 30% O(2), IPF patients did not regulate exertional acidosis by ventilatory compensation to stop exercise, resulting in reaching a specific pH...
  3. pmc Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Japan
    PLoS ONE 7:e35708. 2012
    ..Ghrelin is a novel growth hormone (GH)-releasing peptide with GH-independent effects. The efficacy and safety of adding ghrelin to pulmonary rehabilitation (PR) in cachectic COPD patients were investigated...
  4. doi request reprint Effects of oxygen on exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 17:149-54. 2012
    ..We investigated the exercise responses to hyperoxia in relation to dyspnoea profile, as well as cardiopulmonary, acidotic and sympathetic parameters in 35 patients with stable COPD (mean FEV(1) 46% predicted)...
  5. doi request reprint Exertional dyspnea-related acidotic and sympathetic responses in patients with sequelae of pulmonary tuberculosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    J Physiol Sci 60:187-93. 2010
    ..443, p = 0.0012; r = 0.643, p < 0.0001, respectively, before and after the break point). In TBsq patients during exercise, increases in circulating NE levels and exertional acidosis were correlated with exertional dyspnea...
  6. doi request reprint Acidosis and raised norepinephrine levels are associated with exercise dyspnoea in idiopathic pulmonary fibrosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 14:1020-6. 2009
    ..This study tested the hypothesis in IPF that exertional dyspnoea correlates with cardiopulmonary exercise responses, specifically changes in arterial blood pH and plasma norepinephrine (NE)...
  7. ncbi request reprint The degree of exercise hypoxemia reflects pulmonary artery pressure during early exercise in chronic obstructive pulmonary disease patients
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Clin Physiol Funct Imaging 28:64-9. 2008
    ..In conclusion, the PaO(2)-slope and the SpO(2)-slope reflect Ppa during the early exercise phase. Thus, assessment of these parameters could be useful to evaluate the cardiopulmonary haemodynamic pathophysiology of COPD patients...
  8. pmc Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    BMC Pulm Med 13:37. 2013
    ....
  9. pmc Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients
    Kenji Yoshimura
    Department of Respiratory Medicine, Toneyama National Hospital, Osaka, Japan
    Int J Chron Obstruct Pulmon Dis 7:109-17. 2012
    ..Tiotropium partially relieves exertional dyspnea and reduces the risk of congestive heart failure in chronic obstructive pulmonary disease (COPD) patients. However, its effect on the sympathetic activation response to exercise is unknown...
  10. doi request reprint Identification of three exercise-induced mortality risk factors in patients with COPD
    Kenji Yoshimura
    Department of Respiratory Medicine, National Hospital Organization Toneyama Hospital, Toyonaka City, Osaka, Japan
    COPD 11:615-26. 2014
    ..Thus, these new exercise-induced mortality risk factors may lead to more efficient pulmonary rehabilitation programs for COPD patients based on patient-specific exercise-induced pathophysiological profiles...
  11. ncbi request reprint Infective tricuspid valve endocarditis with pulmonary emboli caused by Campylobacter fetus after tooth extraction
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Osaka
    Intern Med 44:1055-9. 2005
    ..Long-term antibiotic therapy was given, curing the infection with valvuloplasty. We presented the possibility that infective Campylobacter fetus endocarditis after dental treatment was caused by eating raw meat...
  12. doi request reprint Personalized pulmonary rehabilitation and occupational therapy based on cardiopulmonary exercise testing for patients with advanced chronic obstructive pulmonary disease
    Ryoji Maekura
    Department of Respiratory Medicine and Rehabilitation, National Hospital Organization Toneyama Hospital, Toyonaka City, Osaka, Japan
    Int J Chron Obstruct Pulmon Dis 10:1787-800. 2015
    ..Personalized pulmonary rehabilitation including occupational therapy improves the prognosis of patients with advanced COPD...
  13. ncbi request reprint [A case of spontaneous resolution of sarcoidosis with primary pulmonary cavitations]
    Takeo Iwasaki
    Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital
    Nihon Kokyuki Gakkai Zasshi 45:59-64. 2007
    ..The walls of the cavitations gradually thinned and had almost completely vanished after 6 months of careful observation without steroid therapy...
  14. doi request reprint Differences in physiological response to exercise in patients with different COPD severity
    Ryoji Maekura
    Department of Respiratory Medicine, National Hospital Organization Toneyama Hospital, Toyonaka City, Osaka, Japan
    Respir Care 59:252-62. 2014
    ..The present study aimed to characterize life-threatening factors such as hypoxemia, acidosis, and sympathetic activation during exercise in these patients...
  15. pmc Whole-genome sequence of the hypervirulent clinical strain Mycobacterium intracellulare M.i.198
    Yoshitaka Tateishi
    Department of Bacteriology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    J Bacteriol 194:6336. 2012
    ..We report herein the draft genome sequence of Mycobacterium intracellulare clinical strain M.i.198, which consistently exhibits hypervirulence in human patients, human macrophages in vitro, and immunocompetent mice...