Keisuke Miki

Summary

Affiliation: Toneyama National Hospital
Country: Japan

Publications

  1. pmc Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Japan
    PLoS ONE 7:e35708. 2012
  2. ncbi request reprint The degree of exercise hypoxemia reflects pulmonary artery pressure during early exercise in chronic obstructive pulmonary disease patients
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Clin Physiol Funct Imaging 28:64-9. 2008
  3. doi request reprint Acidosis and raised norepinephrine levels are associated with exercise dyspnoea in idiopathic pulmonary fibrosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 14:1020-6. 2009
  4. doi request reprint Exertional dyspnea-related acidotic and sympathetic responses in patients with sequelae of pulmonary tuberculosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    J Physiol Sci 60:187-93. 2010
  5. doi request reprint Effects of oxygen on exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 17:149-54. 2012
  6. doi request reprint Exertional acidotic responses in idiopathic pulmonary fibrosis: the mechanisms of exertional dyspnea
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respir Physiol Neurobiol 185:653-8. 2013
  7. pmc Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    BMC Pulm Med 13:37. 2013
  8. pmc Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients
    Kenji Yoshimura
    Department of Respiratory Medicine, Toneyama National Hospital, Osaka, Japan
    Int J Chron Obstruct Pulmon Dis 7:109-17. 2012
  9. ncbi request reprint Infective tricuspid valve endocarditis with pulmonary emboli caused by Campylobacter fetus after tooth extraction
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Osaka
    Intern Med 44:1055-9. 2005
  10. doi request reprint Differences in physiological response to exercise in patients with different COPD severity
    Ryoji Maekura
    Department of Respiratory Medicine, National Hospital Organization Toneyama Hospital, Toyonaka City, Osaka, Japan
    Respir Care 59:252-62. 2014

Detail Information

Publications11

  1. pmc Ghrelin treatment of cachectic patients with chronic obstructive pulmonary disease: a multicenter, randomized, double-blind, placebo-controlled trial
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Japan
    PLoS ONE 7:e35708. 2012
    ..Ghrelin is a novel growth hormone (GH)-releasing peptide with GH-independent effects. The efficacy and safety of adding ghrelin to pulmonary rehabilitation (PR) in cachectic COPD patients were investigated...
  2. ncbi request reprint The degree of exercise hypoxemia reflects pulmonary artery pressure during early exercise in chronic obstructive pulmonary disease patients
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Clin Physiol Funct Imaging 28:64-9. 2008
    ..In conclusion, the PaO(2)-slope and the SpO(2)-slope reflect Ppa during the early exercise phase. Thus, assessment of these parameters could be useful to evaluate the cardiopulmonary haemodynamic pathophysiology of COPD patients...
  3. doi request reprint Acidosis and raised norepinephrine levels are associated with exercise dyspnoea in idiopathic pulmonary fibrosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 14:1020-6. 2009
    ..This study tested the hypothesis in IPF that exertional dyspnoea correlates with cardiopulmonary exercise responses, specifically changes in arterial blood pH and plasma norepinephrine (NE)...
  4. doi request reprint Exertional dyspnea-related acidotic and sympathetic responses in patients with sequelae of pulmonary tuberculosis
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    J Physiol Sci 60:187-93. 2010
    ..443, p = 0.0012; r = 0.643, p < 0.0001, respectively, before and after the break point). In TBsq patients during exercise, increases in circulating NE levels and exertional acidosis were correlated with exertional dyspnea...
  5. doi request reprint Effects of oxygen on exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respirology 17:149-54. 2012
    ..We investigated the exercise responses to hyperoxia in relation to dyspnoea profile, as well as cardiopulmonary, acidotic and sympathetic parameters in 35 patients with stable COPD (mean FEV(1) 46% predicted)...
  6. doi request reprint Exertional acidotic responses in idiopathic pulmonary fibrosis: the mechanisms of exertional dyspnea
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka, Osaka, Japan
    Respir Physiol Neurobiol 185:653-8. 2013
    ..Regardless of breathing CA or 30% O(2), IPF patients did not regulate exertional acidosis by ventilatory compensation to stop exercise, resulting in reaching a specific pH...
  7. pmc Effects of ghrelin treatment on exercise capacity in underweight COPD patients: a substudy of a multicenter, randomized, double-blind, placebo-controlled trial of ghrelin treatment
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, 5 1 1 Toneyama, Toyonaka, Osaka, Japan
    BMC Pulm Med 13:37. 2013
    ....
  8. pmc Effects of tiotropium on sympathetic activation during exercise in stable chronic obstructive pulmonary disease patients
    Kenji Yoshimura
    Department of Respiratory Medicine, Toneyama National Hospital, Osaka, Japan
    Int J Chron Obstruct Pulmon Dis 7:109-17. 2012
    ..Tiotropium partially relieves exertional dyspnea and reduces the risk of congestive heart failure in chronic obstructive pulmonary disease (COPD) patients. However, its effect on the sympathetic activation response to exercise is unknown...
  9. ncbi request reprint Infective tricuspid valve endocarditis with pulmonary emboli caused by Campylobacter fetus after tooth extraction
    Keisuke Miki
    Department of Internal Medicine, National Hospital Organization Toneyama National Hospital, Osaka
    Intern Med 44:1055-9. 2005
    ..Long-term antibiotic therapy was given, curing the infection with valvuloplasty. We presented the possibility that infective Campylobacter fetus endocarditis after dental treatment was caused by eating raw meat...
  10. doi request reprint Differences in physiological response to exercise in patients with different COPD severity
    Ryoji Maekura
    Department of Respiratory Medicine, National Hospital Organization Toneyama Hospital, Toyonaka City, Osaka, Japan
    Respir Care 59:252-62. 2014
    ..The present study aimed to characterize life-threatening factors such as hypoxemia, acidosis, and sympathetic activation during exercise in these patients...
  11. pmc Whole-genome sequence of the hypervirulent clinical strain Mycobacterium intracellulare M.i.198
    Yoshitaka Tateishi
    Department of Bacteriology, Graduate School of Medicine, Osaka City University, Osaka, Japan
    J Bacteriol 194:6336. 2012
    ..We report herein the draft genome sequence of Mycobacterium intracellulare clinical strain M.i.198, which consistently exhibits hypervirulence in human patients, human macrophages in vitro, and immunocompetent mice...