Noboru Uchide

Summary

Affiliation: Tokyo University of Pharmacy and Life Science
Country: Japan

Publications

  1. ncbi Possible roles of proinflammatory and chemoattractive cytokines produced by human fetal membrane cells in the pathology of adverse pregnancy outcomes associated with influenza virus infection
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Mediators Inflamm 2012:270670. 2012
  2. ncbi Antioxidant therapy as a potential approach to severe influenza-associated complications
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Molecules 16:2032-52. 2011
  3. ncbi Effects of mitogen-activated protein kinase inhibitors on tumor necrosis factor-alpha gene expression and apoptosis induction in cultured human fetal membrane chorion cells infected with influenza virus
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
    Intervirology 50:99-107. 2007
  4. ncbi Inhibition of influenza-virus-induced apoptosis in chorion cells of human fetal membranes by nordihydroguaiaretic Acid
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, and Yoneyama Maternity Hospital, Tokyo, Japan
    Intervirology 48:336-40. 2005
  5. ncbi Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Japan
    Antiviral Res 56:207-17. 2002
  6. ncbi Characterization of monocyte differentiation-inducing (MDI) factors derived from human fetal membrane chorion cells undergoing apoptosis after influenza virus infection
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Int J Biochem Cell Biol 38:1926-38. 2006
  7. ncbi Antiviral function of pyrrolidine dithiocarbamate against influenza virus: the inhibition of viral gene replication and transcription
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
    J Antimicrob Chemother 52:8-10. 2003
  8. ncbi Lactate dehydrogenase leakage as a marker for apoptotic cell degradation induced by influenza virus infection in human fetal membrane cells
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
    Intervirology 52:164-73. 2009
  9. ncbi Imbalance between ROS production and elimination results in apoptosis induction in primary smooth chorion trophoblast cells prepared from human fetal membrane tissues
    Bo Yuan
    Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0355, Japan
    Life Sci 82:623-30. 2008
  10. ncbi A new simple multi-well plate-based assay for monocyte differentiation using human monocytic leukemia THP-1 cells
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
    J Immunol Methods 328:215-9. 2007

Collaborators

Detail Information

Publications15

  1. ncbi Possible roles of proinflammatory and chemoattractive cytokines produced by human fetal membrane cells in the pathology of adverse pregnancy outcomes associated with influenza virus infection
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Mediators Inflamm 2012:270670. 2012
    ....
  2. ncbi Antioxidant therapy as a potential approach to severe influenza-associated complications
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Molecules 16:2032-52. 2011
    ..This review article updates knowledge of antioxidant therapy as a potential approach to severe influenza-associated complications...
  3. ncbi Effects of mitogen-activated protein kinase inhibitors on tumor necrosis factor-alpha gene expression and apoptosis induction in cultured human fetal membrane chorion cells infected with influenza virus
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
    Intervirology 50:99-107. 2007
    ....
  4. ncbi Inhibition of influenza-virus-induced apoptosis in chorion cells of human fetal membranes by nordihydroguaiaretic Acid
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, and Yoneyama Maternity Hospital, Tokyo, Japan
    Intervirology 48:336-40. 2005
    ..We examined effects of an antioxidant, nordihydroguaiaretic acid (NDGA), on apoptosis induction and viral proliferation. Subsequently, the results were compared with those of pyrrolidine dithiocarbamate (PDTC), another antioxidant...
  5. ncbi Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Japan
    Antiviral Res 56:207-17. 2002
    ..The synthesis of specific viral macromolecules at the early stage of infection may play a critical role in the mechanism of apoptosis induction and moderate ROS overproduction may not be involved in the mechanism...
  6. ncbi Characterization of monocyte differentiation-inducing (MDI) factors derived from human fetal membrane chorion cells undergoing apoptosis after influenza virus infection
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    Int J Biochem Cell Biol 38:1926-38. 2006
    ..It is possible that these pathways represent part of the mechanism for birth complications associated with intrauterine influenza infection in pregnancy...
  7. ncbi Antiviral function of pyrrolidine dithiocarbamate against influenza virus: the inhibition of viral gene replication and transcription
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan
    J Antimicrob Chemother 52:8-10. 2003
  8. ncbi Lactate dehydrogenase leakage as a marker for apoptotic cell degradation induced by influenza virus infection in human fetal membrane cells
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
    Intervirology 52:164-73. 2009
    ....
  9. ncbi Imbalance between ROS production and elimination results in apoptosis induction in primary smooth chorion trophoblast cells prepared from human fetal membrane tissues
    Bo Yuan
    Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432 1 Horinouchi, Hachioji, Tokyo 192 0355, Japan
    Life Sci 82:623-30. 2008
    ....
  10. ncbi A new simple multi-well plate-based assay for monocyte differentiation using human monocytic leukemia THP-1 cells
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan
    J Immunol Methods 328:215-9. 2007
    ..This method is sensitive and easy to perform, especially in case of analyzing a large number of samples...
  11. ncbi Differentiation of monocytes to macrophages induced by influenza virus-infected apoptotic cells
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    J Gen Virol 83:747-51. 2002
    ..These results suggested that monocytic THP-1 cells were morphologically and functionally differentiated to macrophages by IV-infected apoptotic cells due to a soluble factor released from the apoptotic cells...
  12. ncbi Semi-quantitative RT-PCR-based assay, improved by Southern hybridization technique, for polarity-specific influenza virus RNAs in cultured cells
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    J Virol Methods 106:125-34. 2002
    ....
  13. ncbi Differential mRNA expression of inflammatory cytokines in cultured human fetal membrane cells responding to influenza virus infection
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
    Biol Pharm Bull 25:239-43. 2002
    ....
  14. ncbi Induction of pro-inflammatory cytokine gene expression and apoptosis in human chorion cells of fetal membranes by influenza virus infection: possible implications for maintenance and interruption of pregnancy during infection
    Noboru Uchide
    Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Tokyo, Japan
    Med Sci Monit 11:RA7-16. 2005
    ..Understanding the interactions would make important contributions to the elucidation of the pathogenesis of influenza virus infection during pregnancy...
  15. ncbi Apoptosis in cultured human fetal membrane cells infected with influenza virus
    Noboru Uchide
    Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan
    Biol Pharm Bull 25:109-14. 2002
    ..We further observed that influenza virus replication is associated with the induction of apoptosis...