Hidekazu Sugiura

Summary

Affiliation: Tokyo Women's Medical University
Country: Japan

Publications

  1. ncbi Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis
    Hidekazu Sugiura
    Dept of Medicine IV, Tokyo Women s Medical Univ, 8 1 Kawada cho, Shinjuku City, Tokyo, Japan 162 8666
    Am J Physiol Renal Physiol 302:F1252-64. 2012
  2. ncbi Recombinant human erythropoietin mitigates reductions in renal klotho expression
    Hidekazu Sugiura
    Department of Medicine IV, Tokyo Women s Medical University, Japan
    Am J Nephrol 32:137-44. 2010
  3. ncbi Beneficial effect of aliskiren combined with olmesartan in reducing urinary protein excretion in patients with chronic kidney disease
    Takahito Moriyama
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Kawada cho 8 1, Shinjyuku ku, Tokyo 162 8666, Japan
    Int Urol Nephrol 44:841-5. 2012
  4. ncbi Klotho reduces apoptosis in experimental ischaemic acute kidney injury via HSP-70
    Hidekazu Sugiura
    Department of Medicine IV, Tokyo Women s Medical University, Tokyo, Japan
    Nephrol Dial Transplant 25:60-8. 2010
  5. ncbi Klotho reduces apoptosis in experimental ischaemic acute renal failure
    Hidekazu Sugiura
    Department of Blood Purification, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku City, Tokyo 162 8666, Japan
    Nephrol Dial Transplant 20:2636-45. 2005
  6. ncbi ATF3 protects against renal ischemia-reperfusion injury
    Takumi Yoshida
    Department of Internal Medicine IV, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku City, Tokyo, Japan 162 8666
    J Am Soc Nephrol 19:217-24. 2008
  7. ncbi Frequency of renal disease in Japan: an analysis of 2,404 renal biopsies at a single center
    Takahito Moriyama
    Department of Medicine IV, Kidney Center, Tokyo Women s Medical University, Shinjuku ku, Tokyo, Japan
    Nephron Clin Pract 115:c227-36. 2010
  8. ncbi Effect of single-dose rituximab on primary glomerular diseases
    Hidekazu Sugiura
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Nephron Clin Pract 117:c98-105. 2011
  9. ncbi CD2AP expression in a renal ischemia/reperfusion injury model and analysis of its related genes using overexpression and RNA interference technique
    Sayoko Nishimura
    Department of Medicine IV, Tokyo Women s Medical University, Japan
    Am J Nephrol 25:373-81. 2005
  10. ncbi Association between clinical characteristics and AL amyloid deposition in the kidney
    Mitsuyo Itabashi
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjuku ku, Tokyo 162 8666, Japan
    Heart Vessels 25:543-8. 2010

Collaborators

Detail Information

Publications20

  1. ncbi Reduced Klotho expression level in kidney aggravates renal interstitial fibrosis
    Hidekazu Sugiura
    Dept of Medicine IV, Tokyo Women s Medical Univ, 8 1 Kawada cho, Shinjuku City, Tokyo, Japan 162 8666
    Am J Physiol Renal Physiol 302:F1252-64. 2012
    ..Taken together, renal fibrosis can trigger a deterioration spiral of Klotho expression, which may be involved in the pathophysiology of CKD progression...
  2. ncbi Recombinant human erythropoietin mitigates reductions in renal klotho expression
    Hidekazu Sugiura
    Department of Medicine IV, Tokyo Women s Medical University, Japan
    Am J Nephrol 32:137-44. 2010
    ....
  3. ncbi Beneficial effect of aliskiren combined with olmesartan in reducing urinary protein excretion in patients with chronic kidney disease
    Takahito Moriyama
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Kawada cho 8 1, Shinjyuku ku, Tokyo 162 8666, Japan
    Int Urol Nephrol 44:841-5. 2012
    ..Blockade of the renin-angiotensin-aldosterone system is a therapeutic mainstay in patients with chronic kidney disease (CKD). However, the renoprotective effect of the novel direct renin inhibitor aliskiren is unknown...
  4. ncbi Klotho reduces apoptosis in experimental ischaemic acute kidney injury via HSP-70
    Hidekazu Sugiura
    Department of Medicine IV, Tokyo Women s Medical University, Tokyo, Japan
    Nephrol Dial Transplant 25:60-8. 2010
    ....
  5. ncbi Klotho reduces apoptosis in experimental ischaemic acute renal failure
    Hidekazu Sugiura
    Department of Blood Purification, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku City, Tokyo 162 8666, Japan
    Nephrol Dial Transplant 20:2636-45. 2005
    ....
  6. ncbi ATF3 protects against renal ischemia-reperfusion injury
    Takumi Yoshida
    Department of Internal Medicine IV, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku City, Tokyo, Japan 162 8666
    J Am Soc Nephrol 19:217-24. 2008
    ..In conclusion, ATF3 plays a protective role in renal ischemia-reperfusion injury and the mechanism of the protection may involve suppression of p53 and induction of p21...
  7. ncbi Frequency of renal disease in Japan: an analysis of 2,404 renal biopsies at a single center
    Takahito Moriyama
    Department of Medicine IV, Kidney Center, Tokyo Women s Medical University, Shinjuku ku, Tokyo, Japan
    Nephron Clin Pract 115:c227-36. 2010
    ..Evaluating the frequency of renal disease according to sex, age, time period and ethnicity is of considerable importance...
  8. ncbi Effect of single-dose rituximab on primary glomerular diseases
    Hidekazu Sugiura
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Nephron Clin Pract 117:c98-105. 2011
    ..Rituximab, which acts by inhibiting CD20-mediated B cell proliferation and differentiation, could be effective in the treatment of nephrotic syndrome as shown in recent reports...
  9. ncbi CD2AP expression in a renal ischemia/reperfusion injury model and analysis of its related genes using overexpression and RNA interference technique
    Sayoko Nishimura
    Department of Medicine IV, Tokyo Women s Medical University, Japan
    Am J Nephrol 25:373-81. 2005
    ..However, the precise properties and its role in the renal tubules have not been clarified...
  10. ncbi Association between clinical characteristics and AL amyloid deposition in the kidney
    Mitsuyo Itabashi
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjuku ku, Tokyo 162 8666, Japan
    Heart Vessels 25:543-8. 2010
    ..These findings suggest that the vascular deposition pattern of amyloid in the kidney is important for determining patient survival and renal outcome...
  11. ncbi Oxidative stress decreases klotho expression in a mouse kidney cell line
    Michihiro Mitobe
    Department of Medicine IV, Tokyo Women s Medical University, Tokyo, Japan
    Nephron Exp Nephrol 101:e67-74. 2005
    ....
  12. ncbi [Case of MMF monotherapy for membranous nephropathy]
    Mioko Kobayashi
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Nihon Jinzo Gakkai Shi 52:572-7. 2010
    ..No digestive symptoms, kidney function worsening or increase in blood pressure were noted during treatment. These findings suggest that MMF monotherapy is effective and safe for the treatment of membranous nephropathy...
  13. ncbi Effect of the antiplatelet agent cilostazol on endovascular inflammatory biochemical parameters and the clinical symptoms of peripheral artery disease and restless legs syndrome in hemodialysis patients
    Shunji Shiohira
    Department of Medicine IV, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku, Tokyo 162 8666, Japan
    Clin Exp Nephrol 15:893-9. 2011
    ..We performed an observational, prospective study to evaluate the effect of cilostazol on several clinical and biochemical parameters in HD patients with PAD and RLS...
  14. ncbi Clinical effects of calcium channel blockers and renin-angiotensin-aldosterone system inhibitors on changes in the estimated glomerular filtration rate in patients with polycystic kidney disease
    Michihiro Mitobe
    Department of Medicine IV, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku ku, Tokyo 162 8666, Japan
    Clin Exp Nephrol 14:573-7. 2010
    ..Thus, whether calcium channel blockers (CCB) are useful for the treatment of hypertension in patients with PKD is questionable...
  15. ncbi Successful use of single-dose rituximab for the maintenance of remission in a patient with steroid-resistant nephrotic syndrome
    Noritomo Kurosu
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Intern Med 48:1901-4. 2009
    ..We conclude that rituximab may be an effective treatment agent for resistant nephrotic syndrome and the peripheral B cell count may be a useful marker in such patients for preventing disease relapse...
  16. ncbi Pharmacokinetics of orally administered tacrolimus in lupus nephritis patients
    Keiko Uchida
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Yakugaku Zasshi 130:113-8. 2010
    ..We recommend that monitoring should be carried out by C(12 h) in lupus nephritis outpatients...
  17. ncbi [Clinico-pathological features and outcome in adult patients with Henoch-Schönlein purpura nephritis]
    Yuki Tsuruta
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Nihon Jinzo Gakkai Shi 52:51-7. 2010
    ..It may be necessary to consider the decrease in nephrons, in accordance with non-immunological glomerular obsolescence, in addition to immunological treatment to clarify the prognosis...
  18. ncbi [Effects of steroid therapy on membranous nephropathy]
    Takashi Takei
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
    Nihon Jinzo Gakkai Shi 50:597-601. 2008
    ..Although membranous nephropathy is a common cause of nephrotic syndrome in adults, its treatment remains under debate...
  19. ncbi [Functional analysis of the left-right determinant inv (inversion of embryonic turning) gene]
    Satsuki Shirota
    Department of Medicine IV, Tokyo Women's Medical University, Tokyo, Japan
    Nippon Jinzo Gakkai Shi 46:676-84. 2004
    ..In contrast, repairing related genes were upregulated. In conclusion, gene expression of inv was modulated under oxidative stress and the inv gene may play a role in repairing and regenerating renal epithelial cells...
  20. ncbi The characteristics of relapse in adult-onset minimal-change nephrotic syndrome
    Takashi Takei
    Department of Medicine, Kidney Center, Tokyo Women s Medical University, 8 1 Kawadacho, Shinjuku ku, Tokyo 162 8666, Japan
    Clin Exp Nephrol 11:214-7. 2007
    ..It is, therefore, necessary to identify factors that can predict this increased risk of relapse in some patients in order to establish useful treatment methods to reduce the risk...