Tomohiko Sato

Summary

Affiliation: Tokyo Medical University
Country: Japan

Publications

  1. doi request reprint Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
    Tomohiko Sato
    Department of Geriatric Medicine, Tokyo Medical University, 6 7 1 Nishishinjuku Shinjuku ku, Tokyo 160 0023, Japan
    Neurobiol Aging 32:1626-33. 2011
  2. ncbi request reprint Deep gray matter hyperperfusion with occipital hypoperfusion in dementia with Lewy bodies
    T Sato
    Department of Geriatric Medicine, Tokyo Medical University, Shinjuku ku, Tokyo, Japan
    Eur J Neurol 14:1299-301. 2007
  3. doi request reprint Rate of progression of Alzheimer's disease in younger versus older patients: a longitudinal single photon emission computed tomography study
    Minoru Sakai
    Department of Geriatric Medicine, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 13:555-62. 2013
  4. doi request reprint The progression of cognitive deterioration and regional cerebral blood flow patterns in Alzheimer's disease: a longitudinal SPECT study
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    J Neurol Sci 290:96-101. 2010
  5. doi request reprint Regional differences in cortical benzodiazepine receptors of Alzheimer, vascular, and mixed dementia patients
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    J Neurol Sci 323:71-6. 2012
  6. doi request reprint Vascular risk factors are associated with faster decline of Alzheimer disease: a longitudinal SPECT study
    Kazumasa Kume
    Department of Geriatric Medicine, Tokyo Medical University, 6 7 1 Nishishinjuku Shinjuku ku, Tokyo 160 0023, Japan
    J Neurol 258:1295-303. 2011
  7. doi request reprint Effects of cilostazol on cognition and regional cerebral blood flow in patients with Alzheimer's disease and cerebrovascular disease: a pilot study
    Hirofumi Sakurai
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 13:90-7. 2013
  8. ncbi request reprint The effect of education on rCBF changes in Alzheimer's disease: a longitudinal SPECT study
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Eur J Nucl Med Mol Imaging 35:2182-90. 2008
  9. doi request reprint Prediction of response to donepezil in Alzheimer's disease: combined MRI analysis of the substantia innominata and SPECT measurement of cerebral perfusion
    Hidekazu Kanetaka
    Department of Geriatric Medicine, Tokyo Medical University, Japan
    Nucl Med Commun 29:568-73. 2008
  10. doi request reprint Vascular risk factors and progression in Alzheimer's disease
    Hirofumi Sakurai
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 11:211-4. 2011

Collaborators

Detail Information

Publications23

  1. doi request reprint Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
    Tomohiko Sato
    Department of Geriatric Medicine, Tokyo Medical University, 6 7 1 Nishishinjuku Shinjuku ku, Tokyo 160 0023, Japan
    Neurobiol Aging 32:1626-33. 2011
    ..Pioglitazone may offer a novel strategy for the treatment of AD...
  2. ncbi request reprint Deep gray matter hyperperfusion with occipital hypoperfusion in dementia with Lewy bodies
    T Sato
    Department of Geriatric Medicine, Tokyo Medical University, Shinjuku ku, Tokyo, Japan
    Eur J Neurol 14:1299-301. 2007
    ..Our results suggest that the addition of deep gray matter hyperperfusion to occipital hypoperfusion may be useful in the clinical differentiation of DLB and AD...
  3. doi request reprint Rate of progression of Alzheimer's disease in younger versus older patients: a longitudinal single photon emission computed tomography study
    Minoru Sakai
    Department of Geriatric Medicine, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 13:555-62. 2013
    ..We investigated the effect of age on the rate of progression of cognitive impairment and on regional cerebral blood flow (rCBF) deficits using longitudinal single photon emission computed tomography (SPECT) studies...
  4. doi request reprint The progression of cognitive deterioration and regional cerebral blood flow patterns in Alzheimer's disease: a longitudinal SPECT study
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    J Neurol Sci 290:96-101. 2010
    ..We examined the possible relationship between the rate of cognitive deterioration and regional cerebral blood flow (rCBF) patterns in patients with AD...
  5. doi request reprint Regional differences in cortical benzodiazepine receptors of Alzheimer, vascular, and mixed dementia patients
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    J Neurol Sci 323:71-6. 2012
    ....
  6. doi request reprint Vascular risk factors are associated with faster decline of Alzheimer disease: a longitudinal SPECT study
    Kazumasa Kume
    Department of Geriatric Medicine, Tokyo Medical University, 6 7 1 Nishishinjuku Shinjuku ku, Tokyo 160 0023, Japan
    J Neurol 258:1295-303. 2011
    ..Multiple vascular risk factors are associated with a greater rate of decline in cognition, function, and rCBF in patients with AD. Our results highlight the contribution of vascular risk factors on the progression of AD...
  7. doi request reprint Effects of cilostazol on cognition and regional cerebral blood flow in patients with Alzheimer's disease and cerebrovascular disease: a pilot study
    Hirofumi Sakurai
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 13:90-7. 2013
    ....
  8. ncbi request reprint The effect of education on rCBF changes in Alzheimer's disease: a longitudinal SPECT study
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Eur J Nucl Med Mol Imaging 35:2182-90. 2008
    ..To determine the relationship of differing levels of education on regional cerebral blood flow (rCBF) in patients with Alzheimer's disease (AD)...
  9. doi request reprint Prediction of response to donepezil in Alzheimer's disease: combined MRI analysis of the substantia innominata and SPECT measurement of cerebral perfusion
    Hidekazu Kanetaka
    Department of Geriatric Medicine, Tokyo Medical University, Japan
    Nucl Med Commun 29:568-73. 2008
    ....
  10. doi request reprint Vascular risk factors and progression in Alzheimer's disease
    Hirofumi Sakurai
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 11:211-4. 2011
    ..To determine whether vascular risk factors such as hypertension, diabetes and hypercholesterolemia affect the progression of Alzheimer's disease (AD)...
  11. doi request reprint Frontal Assessment Battery and brain perfusion images in amnestic mild cognitive impairment
    Kazumasa Kume
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 11:77-82. 2011
    ..To assess the frontal lobe functions of subjects with MCI using the Frontal Assessment Battery (FAB) and to identify the brain regions responsible for FAB performance...
  12. ncbi request reprint [Prediction of the development of Alzheimer disease in patients with mild cognitive impairment]
    Kazumasa Kume
    Department of Geriatric Medicine, Tokyo Medical University
    Nihon Ronen Igakkai Zasshi 47:147-52. 2010
    ....
  13. doi request reprint Subgroups of Alzheimer's disease associated with diabetes mellitus based on brain imaging
    Raita Fukazawa
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo 160 0023, Japan
    Dement Geriatr Cogn Disord 35:280-90. 2013
    ..We attempted to define possible subgroups of Alzheimer's disease (AD) associated with diabetes mellitus (DM) based on brain imaging...
  14. doi request reprint Neuroanatomical correlates of unawareness of memory deficits in early Alzheimer's disease
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Dement Geriatr Cogn Disord 25:347-53. 2008
    ..To investigate neuroanatomical substrates of unawareness of memory deficits in patients with early Alzheimer's disease (AD)...
  15. ncbi request reprint [A patient with early Alzheimer's disease who showed improvement of cognitive function and cerebral perfusion by combined therapy of nilvadipine and PPAR gamma agonists]
    Tomohiko Sato
    Department of Geriatric Medicine, Tokyo Medical University
    Nihon Ronen Igakkai Zasshi 45:428-33. 2008
    ....
  16. ncbi request reprint [Regional cerebral blood flow patterns in extremely elderly patients with Alzheimer's disease]
    Kentaro Hirao
    Department of Geriatric Medicine, Tokyo Medical University
    Nihon Ronen Igakkai Zasshi 45:408-13. 2008
    ....
  17. ncbi request reprint Longitudinal patterns of unawareness of memory deficits in mild Alzheimer's disease
    Tomotaka Akai
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Geriatr Gerontol Int 9:16-20. 2009
    ..However, less is known about the longitudinal progression of this phenomenon. We examined the longitudinal evolution of unawareness in patients with mild AD to determine whether impaired awareness progresses with cognitive decline...
  18. pmc A Longitudinal SPECT Study of Different Patterns of Regional Cerebral Blood Flow in Alzheimer's Disease with or without Diabetes
    Kentaro Hirao
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Dement Geriatr Cogn Disord Extra 1:62-74. 2011
    ..To determine the effect of diabetes mellitus (DM) on regional cerebral blood flow (rCBF) patterns in patients with Alzheimer's disease (AD)...
  19. ncbi request reprint [Elderly case of isolated ACTH deficiency presenting with depression and digestive symptoms]
    Kentaro Hirao
    Department of Geriatric Medicine, Tokyo Medical University
    Nihon Ronen Igakkai Zasshi 44:117-21. 2007
    ..In summary, we report an elderly case of isolated ACTH deficiency with nonspecific initial manifestations such as nausea, fatigue, and depression...
  20. ncbi request reprint [Alzheimer's disease]
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University
    Nihon Rinsho 68:330-4. 2010
    ..In addition, PPARgamma agonists have been shown to inhibit inflammatory gene expression, alter Abeta homeostasis and exhibit neuroprotective effects. PPARgamma agonists represent a new and potentially efficacious treatment of AD...
  21. ncbi request reprint [Awareness of memory deficits in patients with dementias: a study with the Everyday Memory Checklist]
    Haruo Hanyu
    Department of Geriatric Medicine, Tokyo Medical University, Tokyo, Japan
    Nihon Ronen Igakkai Zasshi 44:463-9. 2007
    ....
  22. doi request reprint Prediction model for CD34 positive cell yield in peripheral blood stem cell collection on the fourth day after G-CSF administration in healthy donors
    Tetsuichi Yoshizato
    Department of Transfusion Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Int J Hematol 98:56-65. 2013
    ..When the score is 0 or 1 on day 4, starting apheresis on day 5 potentially helps avoiding the need for multiple harvests. Score 3 or 4 on day 4 is indicative of better performance if apheresis is started on day 4...
  23. doi request reprint Crk-associated substrate lymphocyte type regulates myeloid cell motility and suppresses the progression of leukemia induced by p210Bcr/Abl
    Sachiko Seo
    Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Cancer Sci 102:2109-17. 2011
    ..Thus, Cas-L seems to regulate the progression of CML in a negative way, presumably by attenuating extramedullary hyperplasia...