Emi K Nishimura
Affiliation: Tokyo Medical and Dental University
- Key roles for transforming growth factor beta in melanocyte stem cell maintenanceEmi K Nishimura
Department of Stem Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, 2 3 10 Kandasurugadai, Chiyoda ku, Tokyo 101 0062, Japan
Cell Stem Cell 6:130-40. 2010..These data demonstrate that the TGF-beta signaling pathway is one of the key niche factors that regulate melanocyte stem cell immaturity and quiescence...
- Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentationEmi K Nishimura
Department of Stem Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Chiyoda ku, Tokyo, Japan
Pigment Cell Melanoma Res 24:401-10. 2011..This review focuses on the identification of MelSCs and their characteristics and explains the importance of the MelSC population in the mechanisms of hair pigmentation, hair greying, and skin repigmentation...
- A melanocyte-melanoma precursor niche in sweat glands of volar skinNatsuko Okamoto
Department of Stem Cell Biology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Pigment Cell Melanoma Res 27:1039-50. 2014..These findings indicate that sweat glands maintain melanocyte-melanoma precursors in an immature state in the niche and explain the preferential distribution of early melanoma cells around sweat glands in human volar skin. ..
- A stem cell-derived gene (Sddr) negatively regulates differentiation of embryonic stem cellsMiwako Miura
Department of Stem Cell Biology, Graduate School of Medical Science, Cancer Research Institute, Kanazawa University, Kanazawa, Japan
Int J Dev Biol 54:33-9. 2010..These results suggest that although it is dispensable for ES cell self-renewal, Sddr is a negative regulator of ES cell differentiation...