Affiliation: Tokyo Medical and Dental University
- Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptorTakahiro Satoh
Department of Dermatology, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
J Immunol 177:2621-9. 2006..These findings indicate that the PGD(2)-CRTH2 system plays a significant role in chronic allergic skin inflammation. CRTH2 may represent a novel therapeutic target for treatment of human allergic disorders, including atopic dermatitis...