Research Topics
| K MatsuzakaSummaryAffiliation: Tokyo Dental College Country: Japan Publications
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Detail Information
Publications
Bone formation in beta-tricalcium phosphate-filled bone defects of the rat femur: morphometric analysis and expression of bone related protein mRNAKiyoto Shiratori
Department of Pathology, Oral Health Science Center, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Biomed Res 26:51-9. 2005..Taken together, these results prove that beta-TCP is an appropriate material for osteoconduction and promotes bone formation in bone defects...
Changes in the homeostatic mechanism of dental pulp with age: expression of the core-binding factor alpha-1, dentin sialoprotein, vascular endothelial growth factor, and heat shock protein 27 messenger RNAsKenichi Matsuzaka
Oral Health Science Center, Tokyo Dental College, Chiba, Japan
J Endod 34:818-21. 2008..The self-defense system in young DPCs is undertaken by calcification, but in adult DPCs it is carried out by the expression of self-defense proteins and the regeneration of vessels...
Effects of multigrooved surfaces on osteoblast-like cells in vitro: scanning electron microscopic observation and mRNA expression of osteopontin and osteocalcinK Matsuzaka
Department of Clinical Pathophysiology and Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba, 261 8502 Japan
J Biomed Mater Res A 68:227-34. 2004..These results suggest that multigrooves could be used to control the orientation of mineralized ECM as well as of cells, and also to enhance the production of mineralized ECM...
Canalicular adenoma arising in the upper lip: review of the pathological findingsKenichi Matsuzaka
Department of Clinical Pathophysiology, Oral Health Science Center Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Bull Tokyo Dent Coll 45:229-33. 2004..The tumor cells were immunoreactive to AE1/AE3, CK19 and S-100, were partially positive for CK7, CK8, GFAP and PCNA, but were negative for SMA, CK13, CK14 and vimentin...
Acinic cell carcinoma found by recurrence of a mucous cyst in the sublingual glandKenichi Matsuzaka
Oral Health Science Center, Department of Clinical Pathophysiology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Bull Tokyo Dent Coll 45:95-8. 2004..This report concludes that the pathological diagnosis is beneficial in clarifying the reasons for the recurrence of a benign lesion...
Papillary cystadenoma arising from the upper lip: a case reportKenichi Matsuzaka
Oral Health Science Center, Department of Clinical Pathophysiology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Bull Tokyo Dent Coll 44:213-6. 2003..Only one case (0.9%) of papillary cystadenoma has occurred among the 110 benign intraoral salivary gland tumors seen in our hospital from 1966 through September 2003...
Intravascular papillary endothelial hyperplasia arising from the upper lipKenichi Matsuzaka
Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Bull Tokyo Dent Coll 44:55-9. 2003..This case represents IPEH with high proliferative activity...
The attachment and growth behavior of osteoblast-like cells on microtextured surfacesKenichi Matsuzaka
Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Biomaterials 24:2711-9. 2003..Therefore, microgrooved surfaces seem interesting to be applied on bone-anchored implants...
Age-related differences in expression of vascular endothelial growth factor by periodontal ligament cells in vitroKenichi Matsuzaka
Department of Clinical Pathophysiology, Oral Health Science Center HRC7, Tokyo Dental College, Mihama ku, Chiba, Japan
Bull Tokyo Dent Coll 48:143-6. 2007..In conclusion, the data revealed that PDL cells varied with age, and suggest that in view of such changes in cell proliferation and VEGF mRNA expression, age should be taken into consideration in periodontal treatment...
Effect on the amount of bone-implant contact when splinting immediate-loaded dental implantsKenichi Matsuzaka
Oral Health Science Center HRC7, Department of Clinical Pathophysiology, Tokyo Dental College, 1 2 2, Masago, Mihama ku, Chiba, 261 8502 Japan
Implant Dent 16:309-16. 2007..Much attention has been focused on the immediate or early loading of implants with or without splinting. The purpose of this study was to evaluate the contact rate between bones and implants, with or without splinting...
Age-related differences in localization of beta-defensin-2 in human gingival epitheliaKenichi Matsuzaka
Oral Health Science Center HRC7, Tokyo Dental College, Chiba, Japan
Bull Tokyo Dent Coll 47:167-70. 2006..Furthermore, immunoreaction was stronger in the elderly group. The results revealed HBD-2 positive cells in spinous cells in the elderly group and in the parakeratinized layer in the young group...
Effects of epidermal growth factor and/or nerve growth factor on Malassez's epithelial rest cells in vitro: expression of mRNA for osteopontin, bone morphogenetic protein 2 and vascular endothelial growth factorK Yamawaki
Department of Clinical Pathophysiology, Tokyo Dental College, Masago, Mihama ku, Chiba, Japan
J Periodontal Res 45:421-7. 2010..The purpose of this study was to determine the effects of epidermal growth factor (EGF) and/or nerve growth factor (NGF) in vitro on these functions of MER cells...
Bone response to calcium phosphate-coated and bisphosphonate-immobilized titanium implantsM Yoshinari
Department of Dental Materials Science, Oral Health Science Center, Tokyo Dental College, Chiba, Japan
Biomaterials 23:2879-85. 2002..These data suggest that a thin coating of calcium phosphate followed by bisphosphonate-immobilization is effective in the promotion of osteogenesis on surfaces of dental implants...
A case of an ameloblastic fibro-odontoma arising from a calcifying odontogenic cystK Matsuzaka
Oral Health Science Center, Department of Pathology, Tokyo Dental College, Chiba, Japan
Bull Tokyo Dent Coll 42:51-5. 2001..Cytokeratin 19 was strongly immunoreactive in the epithelium of the lesion; osteopontin and osteocalcin reacted in the mesenchymal cells and weakly in the epithelial element of this tumor...
Cellular responses of rat periodontal ligament cells under hypoxia and re-oxygenation conditions in vitroH Amemiya
Department of Clinical Pathophysiology, Tokyo Dental College, Chiba, Japan
J Periodontal Res 43:322-7. 2008..The aim of this study was to investigate the responses of periodontal ligament cells under hypoxia and re-oxygenation conditions in vitro...
Effects of multigrooved surfaces on fibroblast behaviorM Yoshinari
Department of Dental Materials Science and Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
J Biomed Mater Res A 65:359-68. 2003..These results suggest that multigrooves can control the orientation of ECM as well as cells and thus enhance the production of ECM...
Analysis of side population cells derived from dental pulp tissueM Kenmotsu
Oral Health Science Center HRC7, Tokyo Dental Collage, Chiba, Japan
Int Endod J 43:1132-42. 2010..To investigate the characteristics of side population (SP) cells derived from the dental pulp of young and aged rats...
Characteristics of newly formed bone during guided bone regeneration: observations by immunohistochemistry and confocal laser scanning microscopyK Matsuzaka
Department of Clinical Pathophysiology, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Bull Tokyo Dent Coll 42:225-34. 2001..These results suggest that GBR accelerates the migration of osteogenic cells, the formation of new bone, and mineralization in the defect created by the e-PTFE membrane...
An experimental study on the features of peri-implant epithelium: immunohistochemical and electron-microscopic observationsMasatsugu Fujiseki
Oral Health Science Center, Department of Pathology, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Bull Tokyo Dent Coll 44:185-99. 2003..Taken together, the peri-implant epithelium is similar to that seen in the oral mucosa, and it is structurally different from the junctional epithelium...
Morphological and molecular changes in denture-supporting tissues under persistent mechanical stress in ratsM Tsuruoka
Department of Removable Prosthodontics and Gerodontology, Oral Health Science Center, Tokyo Dental College, Mihama ku, Chiba, Japan
J Oral Rehabil 35:889-97. 2008....
Oncocytic tumor in myoepithelioma arising from the grossopalatine glandK Matsuzaka
Oral Health Science Center, Tokyo Dental College, 1 2 2, Masago, Mihama ku, Chiba 261 8502, Japan
Oral Oncol 39:306-8. 2003..The oncocytic tumor contained large amounts of eosinophilic granular cytoplasm and small nuclei...
Morphology of Malassez's epithelial rest-like cells in the cementum: transmission electron microscopy, immunohistochemical, and TdT-mediated dUTP-biotin nick end labeling studiesM Suzuki
Oral Health Science Center and Department of Periodontics, Tokyo Dental College, Chiba, Japan
J Periodontal Res 41:280-7. 2006....
Galanin inhibits calcium channels via Galpha(i)-protein mediated by GalR1 in rat nucleus tractus solitariusTakayuki Endoh
Oral Health Science Center HRC7, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Brain Res 1229:37-46. 2008..These results indicate that GAL inhibits N- and P/Q-types VDCCs via Galpha(i)-protein betagamma subunits mediated by GalR1 in NTS...
Nerve growth factor and brain-derived neurotrophic factor attenuate angiotensin-II-induced facilitation of calcium channels in acutely dissociated nucleus tractus solitarii neurons of the ratTakayuki Endoh
Oral Health Science Center HRC7, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Arch Oral Biol 53:1192-201. 2008..This study aimed to investigate the hypothesis that NGF and BDNF interfere with angiotensin-II- and glutamate-induced facilitation of voltage-dependent Ca(2+) channels (VDCCs) in nucleus tractus solitarius (NTS) neurons...
Behavior of rat periodontal ligament cells on fibroblast growth factor-2-immobilized titanium surfaces treated by plasma modificationEitoyo Kokubu
Department of Clinical Pathophysiology and Oral Health Science Center, Tokyo Dental College, Mihama ku, Chiba 261 8501, Japan
J Biomed Mater Res A 91:69-75. 2009..Immobilized FGF-2, although inferior to culture medium with FGF-2, influenced the proliferation of PDL cells and might have promoted collagen and vascular synthesis...
Prevention of biofilm formation on titanium surfaces modified with conjugated molecules comprised of antimicrobial and titanium-binding peptidesMasao Yoshinari
Division of Oral Implants Research and HRC7, Oral Health Science Center, Tokyo Dental College, Mihama ku, Chiba, Japan
Biofouling 26:103-10. 2010..These results indicate that surface modification with conjugated molecules consisting of antimicrobial and Ti-binding peptides is a promising method for reduction of biofilm formation on Ti surfaces...
Controlled release of simvastatin acid using cyclodextrin inclusion systemMasao Yoshinari
Oral Health Science Center HRC7, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Dent Mater J 26:451-6. 2007..Besides, the amount of crystalline complexes in the coatings increased with decrease in pH. These results suggested that the release rate of SVA depended on two factors: pH of the solution and concomitant crystallinity of the coating...
Leukemia case in patient with taste dysfunctionMasakazu Tazaki
Department of Physiology, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Bull Tokyo Dent Coll 46:33-6. 2005..A blood cell count was also performed simultaneously and promyelocytic leukemia was identified. This case provides an example of leukemia being detected at the time of a blood test being given to assess taste dysfunction...
Oxygen plasma surface modification enhances immobilization of simvastatin acidMasao Yoshinari
Department of Dental Materials Science, Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Mihama ku, Chiba 261 8502, Japan
Biomed Res 27:29-36. 2006....
Adsorption behavior of antimicrobial peptide histatin 5 on PMMAMasao Yoshinari
Department of Dental Materials Science and Oral Health Science Center, Tokyo Dental College, 1 2 2 Masago, Chiba 261 8502, Japan
J Biomed Mater Res B Appl Biomater 77:47-54. 2006..albicans initially attached. On the contrary, the amount of C. albicans colonization on histatin-adsorbed PMMA was significantly less than the control...
Cell proliferation and cell death in periodontal ligaments during orthodontic tooth movementR Mabuchi
Department of Pathology, Tokyo Dental College, Chiba, Japan
J Periodontal Res 37:118-24. 2002..The data also suggest that the ratios of cell proliferation and of cell death are closely related to the regeneration and reconstruction of periodontal ligaments which reflect the orthodontic force...
Tenascin-C promotes differentiation of rat dental pulp cells in vitroK Matsuoka
Oral Health Science Center HRC7, Tokyo Dental College, Chiba, Tokyo, Japan
Int Endod J 46:30-9. 2013..To investigate the effects of tenascin-C (TN-C) on cultured rat dental pulp cells in relation to the expression of Notch signalling...
Morphohistological change and expression of HSP70, osteopontin and osteocalcin mRNAs in rat dental pulp cells with orthodontic tooth movementSatoshi Shigehara
Department of Clinical Pathophysiology, Tokyo Dental College, Japan
Bull Tokyo Dent Coll 47:117-24. 2006..This suggests that orthodontic tooth movement causes degenerative changes and apoptosis in pulp cells, while pulp homeostasis is maintained at the genetic level...
Cell proliferation and expression of Cbfa-1 in a peripheral osteo-chondroma arising from the mandibular oral mucosa of an edentulous alveolar ridgeKenichi Matsuzaka
Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Bull Tokyo Dent Coll 43:181-5. 2002....
The effect of surface pore size on the differentiation of rat bone marrow cells: morphological observations and expression of bone related protein mRNAMasanori Nashimoto
Department of Pathology, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Bull Tokyo Dent Coll 45:201-11. 2004..2 microm Millipore filter pore size is the most suitable for inducing RBM to differentiate into an osteoblastic phenotype among these surfaces and is probably related to production of the ECM but not to the phenomenon of cell spreading...
Two cases of schwannoma with marked cystic changesM Wakoh
Department of Oral and Maxillofacial Radiology, Tokyo Dental College, Chiba, 261 8502, Japan
Dentomaxillofac Radiol 34:44-50. 2005..Benign pleomorphic adenoma was suspected, but histopathological examination identified schwannoma, predominantly comprising Antoni B type tissue...
Low-level (gallium-aluminum-arsenide) laser irradiation of Par-C10 cells and acinar cells of rat parotid glandKatsuhiro Onizawa
Department of Pathology, Tokyo Dental College, Mihama ku, Chiba, Japan
Lasers Med Sci 24:155-61. 2009....
Characteristics of newly formed bone during guided bone regeneration: analysis of cbfa-1, osteocalcin, and VEGF expressionShiho Tanaka
Department of Clinical Pathophysiology, Tokyo Dental College, 1 2 2, Masago, Mihama ku, Chiba 261 8502, Japan
J Oral Implantol 33:321-6. 2007..These findings suggested that osteogenic cells differentiated into osteoblasts in the membrane-covered defects and that the bone healing process would be completed at an early stage...
The effect of Emdogain on ectopic bone formation in tubes of rat demineralized dentin matrixYoshihiko Koike
Department of Clinical Pathophysiology, Tokyo Dental College, Chiba, Japan
J Periodontal Res 40:385-94. 2005..CONCLUSION: These results suggest that neither EMD nor PGA has the ability to induce hard tissue and that EMPs contained within EMD might aggregate on the dentin surface and inhibit the effect of the demineralized dentin matrix...
Lesions related to the formation of bone, cartilage or cementum arising in the oral area: a statistical study and review of the literatureKenichi Matsuzaka
Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Bull Tokyo Dent Coll 43:173-80. 2002..The patients' ages ranged from 3 to 84 years, and the mean was 40.1 years old. Lesions with hard tissue formation were observed most frequently in the third decade and in the mandibular molar region...
Adenomatoid odontogenic tumor arising from the mandibular molar region: a case report and review of the literatureDaisuke Sato
Department of Clinical Pathophysiology, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan
Bull Tokyo Dent Coll 45:223-7. 2004..The present case lends support to the categorization of AOT as an odontogenic tumor consisting of a disorderly mixture of odontogenic epithelium and odontogenic ectomesenchyme with calcification...
Periodontal ligament and gingival fibroblast adhesion to dentin-like textured surfacesCorinna Bruckmann
Department of Periodontology and Biomaterials, College of Dental Science, University Medical Centre Nijmegen, P.O. Box 9101, Nijmegen 6500 HB, The Netherlands
Biomaterials 26:339-46. 2005..However, considerable differences were observed between primary cells from different animals. Therefore, final efficacy of the surfaces remains to be proven in implantation experiments...
Characterization of the peri-implant epithelium in hamster palatine mucosa: behavior of Merkel cells and nerve endingsYuta Suzuki
Department of Crown and Bridge Prosthodontics, Tokyo Dental College
Biomed Res 26:257-69. 2005..However, regenerative nerve fibers seem to play essential roles as part of the defense and sensory systems around the peri-implant epithelium to compensate for the weakened defense mechanism...
An updated clinical and epidemiological profile of the adenomatoid odontogenic tumour: a collaborative retrospective studyHans Peter Philipsen
Edificio El Condor 30, Urb Guadalmina Alta, San Pedro de Alcantara, Spain
J Oral Pathol Med 36:383-93. 2007..Adenomatoid odontogenic tumour (AOT) is a benign odontogenic jaw lesion. The aim of this study was to update the biological profile of AOT...
