Tetsuo Kubota

Summary

Affiliation: Tokyo Medical and Dental University
Country: Japan

Publications

  1. doi request reprint Possible involvement of chemokine-induced platelet activation in thrombophilic diathesis of antiphospholipid syndrome
    Tetsuo Kubota
    Tokyo Medical and Dental University Graduate School of Health Care Sciences, Department of Microbiology and Immunology, Tokyo, Japan
    Ann N Y Acad Sci 1173:137-45. 2009
  2. ncbi request reprint Anti-tumor necrosis factor therapy does not diminish the immune response to influenza vaccine in Japanese patients with rheumatoid arthritis
    Tetsuo Kubota
    Tokyo Medical and Dental University Graduate School of Health Sciences, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Mod Rheumatol 17:531-3. 2007
  3. pmc NF-kappaB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor
    Tetsuo Kubota
    Department of Microbiology and Immunology, Tokyo Medical and Dental University Graduate School of Health Sciences, Tokyo, Japan
    Arthritis Res Ther 9:R97. 2007
  4. ncbi request reprint Cryopyrin-associated periodic syndromes: background and therapeutics
    Tetsuo Kubota
    Graduate School of Health Care Sciences, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8510, Japan
    Mod Rheumatol 20:213-21. 2010
  5. pmc Effect of a small molecule inhibitor of nuclear factor-kappaB nuclear translocation in a murine model of arthritis and cultured human synovial cells
    Kyoko Wakamatsu
    Department of Microbiology and Immunology, Tokyo Medical and Dental University Graduate School of Health Sciences, Tokyo, Japan
    Arthritis Res Ther 7:R1348-59. 2005
  6. ncbi request reprint Inhibition of fractalkine ameliorates murine collagen-induced arthritis
    Toshihiro Nanki
    Department of Medicine and Rheumatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Immunol 173:7010-6. 2004
  7. ncbi request reprint Retinoid ameliorates experimental autoimmune myositis, with modulation of Th cell differentiation and antibody production in vivo
    Naho Ohyanagi
    Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Rheum 60:3118-27. 2009
  8. doi request reprint Infected abdominal aortic aneurysm caused by nontyphoid Salmonella in an immunocompromised patient with rheumatoid arthritis
    Kayoko Kaneko
    Department of Medicine and Rheumatology, Tokyo Medical and Dental University, 1 5 45, Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    J Infect Chemother 15:312-5. 2009
  9. pmc Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity
    Fumihito Suzuki
    Department of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Arthritis Res Ther 14:R48. 2012
  10. ncbi request reprint Inhibition of the NF-κB pathway as a candidate therapeutic strategy for cryopyrin-associated periodic syndrome
    Satoka Shimogaki
    Department of Microbiology and Immunology, Tokyo Medical and Dental University Graduate School of Health Care Sciences, Tokyo, Japan
    Mod Rheumatol 24:517-24. 2014

Collaborators

Detail Information

Publications20

  1. doi request reprint Possible involvement of chemokine-induced platelet activation in thrombophilic diathesis of antiphospholipid syndrome
    Tetsuo Kubota
    Tokyo Medical and Dental University Graduate School of Health Care Sciences, Department of Microbiology and Immunology, Tokyo, Japan
    Ann N Y Acad Sci 1173:137-45. 2009
    ..These results suggest that the NF-kappaB pathway may be a potential therapeutic target relating to both the coagulation pathway and platelet activity...
  2. ncbi request reprint Anti-tumor necrosis factor therapy does not diminish the immune response to influenza vaccine in Japanese patients with rheumatoid arthritis
    Tetsuo Kubota
    Tokyo Medical and Dental University Graduate School of Health Sciences, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Mod Rheumatol 17:531-3. 2007
  3. pmc NF-kappaB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor
    Tetsuo Kubota
    Department of Microbiology and Immunology, Tokyo Medical and Dental University Graduate School of Health Sciences, Tokyo, Japan
    Arthritis Res Ther 9:R97. 2007
    ....
  4. ncbi request reprint Cryopyrin-associated periodic syndromes: background and therapeutics
    Tetsuo Kubota
    Graduate School of Health Care Sciences, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8510, Japan
    Mod Rheumatol 20:213-21. 2010
    ....
  5. pmc Effect of a small molecule inhibitor of nuclear factor-kappaB nuclear translocation in a murine model of arthritis and cultured human synovial cells
    Kyoko Wakamatsu
    Department of Microbiology and Immunology, Tokyo Medical and Dental University Graduate School of Health Sciences, Tokyo, Japan
    Arthritis Res Ther 7:R1348-59. 2005
    ....
  6. ncbi request reprint Inhibition of fractalkine ameliorates murine collagen-induced arthritis
    Toshihiro Nanki
    Department of Medicine and Rheumatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Immunol 173:7010-6. 2004
    ..Our results suggest that anti-FKN mAb ameliorates arthritis by inhibiting infiltration of inflammatory cells into the synovium. Thus, FKN can be a new target molecule for the treatment of RA...
  7. ncbi request reprint Retinoid ameliorates experimental autoimmune myositis, with modulation of Th cell differentiation and antibody production in vivo
    Naho Ohyanagi
    Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Rheum 60:3118-27. 2009
    ..The present study was undertaken to examine the effects of a synthetic retinoid, Am80, on experimental autoimmune myositis as well as on Th phenotype development and antibody production...
  8. doi request reprint Infected abdominal aortic aneurysm caused by nontyphoid Salmonella in an immunocompromised patient with rheumatoid arthritis
    Kayoko Kaneko
    Department of Medicine and Rheumatology, Tokyo Medical and Dental University, 1 5 45, Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    J Infect Chemother 15:312-5. 2009
    ....
  9. pmc Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity
    Fumihito Suzuki
    Department of Medicine and Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Arthritis Res Ther 14:R48. 2012
    ....
  10. ncbi request reprint Inhibition of the NF-κB pathway as a candidate therapeutic strategy for cryopyrin-associated periodic syndrome
    Satoka Shimogaki
    Department of Microbiology and Immunology, Tokyo Medical and Dental University Graduate School of Health Care Sciences, Tokyo, Japan
    Mod Rheumatol 24:517-24. 2014
    ..Cryopyrin-associated periodic syndrome (CAPS) is caused by unrestricted IL-1β release due to mutation of the gene coding NLRP3. This study aimed to clarify whether NLRP3-related IL-1β release is dependent on the NF-κB pathway...
  11. ncbi request reprint Excessive production of IFN-gamma in patients with systemic lupus erythematosus and its contribution to induction of B lymphocyte stimulator/B cell-activating factor/TNF ligand superfamily-13B
    Masayoshi Harigai
    Department of Pharmacovigilance, Tokyo Medical and Dental University Graduate School of Medicine, Tokyo, Japan
    J Immunol 181:2211-9. 2008
    ....
  12. ncbi request reprint A case of Muckle-Wells syndrome caused by a novel H312P mutation in NALP3 (cryopyrin)
    Ryuji Koike
    Department of Pharmacovigilance, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Mod Rheumatol 17:496-9. 2007
    ..The diagnosis was established on the basis of a typical clinical picture together with a missense mutation, which replaced an amino acid adjacent to one in an earlier reported case of MWS resembling this one...
  13. ncbi request reprint [An autopsy case of intestinal Behcet's disease with sacroiliitis accompanied by myelodysplastic syndrome with trisomy 8. ]
    Rieko Tsubata
    Department of Rheumatology, Tokyo Medical and Dental University, Tokyo, Japan
    Nihon Rinsho Meneki Gakkai Kaishi 28:48-55. 2005
    ..We reviewed similar cases reported and investigated the association of intestinal Behcet's disease with trisomy 8. The association of sacroiliitis with Behcet's disease is also studied...
  14. doi request reprint Clinical characteristics and risk factors for Pneumocystis jirovecii pneumonia in patients with rheumatoid arthritis receiving adalimumab: a retrospective review and case-control study of 17 patients
    Kaori Watanabe
    Department of Pharmacovigilance, Graduate School of Medical and Dental Sciences, Tokyo Medical Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Mod Rheumatol 23:1085-93. 2013
    ..To investigate the clinical characteristics and risk factors of Pneumocystis jirovecii pneumonia (PCP) in rheumatoid arthritis (RA) patients treated with adalimumab...
  15. doi request reprint Spinocerebellar ataxias type 27 derived from a disruption of the fibroblast growth factor 14 gene with mimicking phenotype of paroxysmal non-kinesigenic dyskinesia
    Keiko Shimojima
    Tokyo Women s Medical University Institute for Integrated Medical Sciences, Shinjuku Ward, Tokyo, Japan
    Brain Dev 34:230-3. 2012
    ..Further studies should be conducted on the phenotypic heterogeneity of FGF14 mutations and/or haploinsufficiency in SCA27 and PNKD...
  16. ncbi request reprint The emergence of anti-dsDNA antibodies precedes nucleosome-specific antibodies in MRL/lpr and MRL/+ mice
    Qing Lu
    Tokyo Medical and Dental University Graduate School of Allied Health Sciences, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    J Med Dent Sci 50:9-15. 2003
    ....
  17. doi request reprint Varicella-zoster virus hepatitis in polymyositis
    Fumitaka Mizoguchi
    Department of Medicine and Rheumatology, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo, Japan
    Mod Rheumatol 18:301-5. 2008
    ..Physicians should be aware that VZV infection could complicate severe hepatitis in immuno-suppressed patients...
  18. doi request reprint Amplitude spectral analyses of disorganized patterns on electroencephalograms in preterm infants
    Masako Saito
    Department of Pediatrics, Juntendo University, Faculty of Medicine, Bunkyo ku, Tokyo, Japan
    Brain Dev 35:38-44. 2013
    ..Amplitude spectral analyses will contribute to objective evaluation of disorganized patterns...
  19. doi request reprint Acute encephalopathy in children with Dravet syndrome
    Akihisa Okumura
    Department of Pediatrics, Juntendo University Faculty of Medicine, Bunkyo ku, Tokyo, Japan
    Epilepsia 53:79-86. 2012
    ..The occurrence of acute encephalopathy in children with Dravet syndrome has been reported sporadically. This study clarified the features of acute encephalopathy in children with Dravet syndrome...
  20. ncbi request reprint Phenytoin desensitization monitored by antigen specific T cell response using carboxyfluorescein succinimidyl ester dilution assay
    Akihisa Okumura
    Department of Pediatrics, Juntendo University School of Medicine, 2 1 1 Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Eur J Paediatr Neurol 11:385-8. 2007
    ..After desensitization, phenytoin-specific CFSElow CD4+ cells decreased to background level. These results indicate that CFSE dilution assay will be useful for the diagnosis and monitoring of drug hypersensitivity...