Hideyuki Koga

Summary

Affiliation: Tokyo Medical and Dental University
Country: Japan

Publications

  1. pmc Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect
    Hideyuki Koga
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Res Ther 10:R84. 2008
  2. doi request reprint Effect of posterolateral bundle graft fixation angles on graft tension curves and load sharing in double-bundle anterior cruciate ligament reconstruction using a transtibial drilling technique
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Arthroscopy 29:529-38. 2013
  3. doi request reprint The effect of graft fixation angles on anteroposterior and rotational knee laxity in double-bundle anterior cruciate ligament reconstruction: evaluation using computerized navigation
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Am J Sports Med 40:615-23. 2012
  4. doi request reprint Surgical management of grade 3 medial knee injuries combined with cruciate ligament injuries
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Knee Surg Sports Traumatol Arthrosc 20:88-94. 2012
  5. ncbi request reprint Exogenous synovial stem cells adhere to defect of meniscus and differentiate into cartilage cells
    Keisuke Mizuno
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Japan
    J Med Dent Sci 55:101-11. 2008
  6. doi request reprint [Articular cartilage regeneration with synovial mesenchymal stem cells]
    Ichiro Sekiya
    Section of Cartilage Regeneration, Tokyo Medical and Dental University, Tokyo, Japan
    Clin Calcium 21:879-89. 2011
  7. doi request reprint Analysis of the chondrogenic potential of human synovial stem cells according to harvest site and culture parameters in knees with medial compartment osteoarthritis
    Tsuyoshi Nagase
    Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Rheum 58:1389-98. 2008
  8. doi request reprint Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit
    Hideyuki Koga
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Cell Tissue Res 333:207-15. 2008
  9. pmc Analysis of human synovial and bone marrow mesenchymal stem cells in relation to heat-inactivation of autologous and fetal bovine serums
    Akimoto Nimura
    Section of Cartilage Regeneration, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BMC Musculoskelet Disord 11:208. 2010
  10. pmc Transplantation of Achilles tendon treated with bone morphogenetic protein 7 promotes meniscus regeneration in a rat model of massive meniscal defect
    Nobutake Ozeki
    Tokyo Medical and Dental University, Tokyo, Japan Yokohama City University, Yokohama, Japan
    Arthritis Rheum 65:2876-86. 2013

Collaborators

Detail Information

Publications32

  1. pmc Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect
    Hideyuki Koga
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Res Ther 10:R84. 2008
    ..We have developed a novel transplantation method with synovial mesenchymal stem cells (MSCs) to adhere to the cartilage defect...
  2. doi request reprint Effect of posterolateral bundle graft fixation angles on graft tension curves and load sharing in double-bundle anterior cruciate ligament reconstruction using a transtibial drilling technique
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Arthroscopy 29:529-38. 2013
    ..To evaluate the effect of posterolateral bundle (PLB) graft fixation angles on graft tension curves and load sharing between the anteromedial bundle (AMB) and the PLB in double-bundle anterior cruciate ligament (ACL) reconstruction...
  3. doi request reprint The effect of graft fixation angles on anteroposterior and rotational knee laxity in double-bundle anterior cruciate ligament reconstruction: evaluation using computerized navigation
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    Am J Sports Med 40:615-23. 2012
    ....
  4. doi request reprint Surgical management of grade 3 medial knee injuries combined with cruciate ligament injuries
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Knee Surg Sports Traumatol Arthrosc 20:88-94. 2012
    ..The purpose of this study was to assess clinical outcome for patients with grade 3 valgus instability who were treated according to our surgical management strategy...
  5. ncbi request reprint Exogenous synovial stem cells adhere to defect of meniscus and differentiate into cartilage cells
    Keisuke Mizuno
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Japan
    J Med Dent Sci 55:101-11. 2008
    ..GFP mRNA expressions were not observed in distant organs at day 1. After intra-articular injection, synovial MSCs attached to the meniscal defect and differentiated into cartilage cells...
  6. doi request reprint [Articular cartilage regeneration with synovial mesenchymal stem cells]
    Ichiro Sekiya
    Section of Cartilage Regeneration, Tokyo Medical and Dental University, Tokyo, Japan
    Clin Calcium 21:879-89. 2011
    ..To date, no adverse events have been reported in the study. Regeneration of cartilage, reduction in defect size and an improvement of symptoms have been obtained in most patients over the last 3 years...
  7. doi request reprint Analysis of the chondrogenic potential of human synovial stem cells according to harvest site and culture parameters in knees with medial compartment osteoarthritis
    Tsuyoshi Nagase
    Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Rheum 58:1389-98. 2008
    ....
  8. doi request reprint Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit
    Hideyuki Koga
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Cell Tissue Res 333:207-15. 2008
    ..Higher cell density and a periosteum patch were needed to obtain a high production of cartilage matrix by synovium-MSCs...
  9. pmc Analysis of human synovial and bone marrow mesenchymal stem cells in relation to heat-inactivation of autologous and fetal bovine serums
    Akimoto Nimura
    Section of Cartilage Regeneration, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    BMC Musculoskelet Disord 11:208. 2010
    ..To examine whether heat-inactivation of serum affected the proliferation and whether autologous human serum influenced their multipotentiality...
  10. pmc Transplantation of Achilles tendon treated with bone morphogenetic protein 7 promotes meniscus regeneration in a rat model of massive meniscal defect
    Nobutake Ozeki
    Tokyo Medical and Dental University, Tokyo, Japan Yokohama City University, Yokohama, Japan
    Arthritis Rheum 65:2876-86. 2013
    ..Additionally, we analyzed the relative contributions of host and donor cells on the healing process after tendon transplantation in a rat model...
  11. ncbi request reprint FGF2 and dexamethasone increase the production of hyaluronan in two-dimensional culture of elastic cartilage-derived cells: in vitro analyses and in vivo cartilage formation
    Akiko Yokoyama
    Section of Orthopaedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Cell Tissue Res 329:469-78. 2007
    ..The synthesis of gelatinous matrix in vitro and the formation of cartilage tissue in vivo could be obtained only for the combination of elastic cartilage-derived cells with redifferentiation medium...
  12. ncbi request reprint Meniscus regeneration by syngeneic, minor mismatched, and major mismatched transplantation of synovial mesenchymal stem cells in a rat model
    Makiko Okuno
    Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan Department of Orthopaedic Surgery, Hyogo College of Medicine, Tokyo, Japan
    J Orthop Res 32:928-36. 2014
    ..Syngeneic and minor mismatched transplantation of synovial MSCs promoted meniscus regeneration better than major mismatched transplantation in a rat meniscectmized model...
  13. doi request reprint Human mesenchymal stem cells in synovial fluid increase in the knee with degenerated cartilage and osteoarthritis
    Ichiro Sekiya
    Section of Cartilage Regeneration, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    J Orthop Res 30:943-9. 2012
    ..We listed 20 genes which were expressed higher in both SYN MSCs and SF MSCs than in BM MSCs, and 3 genes were confirmed by quantitative RT-PCR. MSCs in SF increased along with degenerated cartilage and osteoarthritis...
  14. doi request reprint Increased proliferation of human synovial mesenchymal stem cells with autologous human serum: comparisons with bone marrow mesenchymal stem cells and with fetal bovine serum
    Akimoto Nimura
    Tokyo Medical and Dental University, Bunkyo ku, Tokyo, Japan
    Arthritis Rheum 58:501-10. 2008
    ..Since effectiveness of the sera might depend on the origin of the MSCs, we also examined bone marrow MSCs...
  15. ncbi request reprint A retrospective study of the midterm outcome of two-bundle anterior cruciate ligament reconstruction using quadrupled semitendinosus tendon in comparison with one-bundle reconstruction
    Takeshi Muneta
    Department of Orthopedic Surgery, School of Medicine, Tokyo Medical and Dental University Hospital, Tokyo, Japan
    Arthroscopy 22:252-8. 2006
    ....
  16. ncbi request reprint Synovial stem cells are regionally specified according to local microenvironments after implantation for cartilage regeneration
    Hideyuki Koga
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519 Japan
    Stem Cells 25:689-96. 2007
    ..Our results will advance MSC-based therapeutic strategies for cartilage injury and provide the clues for the mechanisms that govern multilineage differentiation of MSCs...
  17. doi request reprint Remnant volume of anterior cruciate ligament correlates preoperative patients' status and postoperative outcome
    Takeshi Muneta
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital, 1 5 45 Yushima, Bunkyo ku, Tokyo, 113 8519, Japan
    Knee Surg Sports Traumatol Arthrosc 21:906-13. 2013
    ..A cohort study was conducted to evaluate the correlation of anterior cruciate ligament (ACL) remnant volume with preoperative status and postoperative outcome of the patients after a remnant-preserving double-bundle (DB) ACL reconstruction...
  18. doi request reprint Morphological differences during in vitro chondrogenesis of bone marrow-, synovium-MSCs, and chondrocytes
    Shizuko Ichinose
    Instrumental Analysis Research Center, Tokyo Medical and Dental University, Tokyo 113 8519, Japan
    Lab Invest 90:210-21. 2010
    ..In this study, we revealed morphological differences of bone marrow-MSCs, synovium-MSCs, and chondrocytes during in vitro chondrogenesis. The most obvious differences in the three populations were observed at day 1 in the deep zone...
  19. doi request reprint Synovial mesenchymal stem cells accelerate early remodeling of tendon-bone healing
    Young Jin Ju
    Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Cell Tissue Res 332:469-78. 2008
    ..DiI-labeled cells could no longer be observed. Implantation of synovial MSCs into bone tunnel thus accelerated early remodeling of tendon-bone healing, as shown histologically...
  20. ncbi request reprint A prospective randomized study of 4-strand semitendinosus tendon anterior cruciate ligament reconstruction comparing single-bundle and double-bundle techniques
    Takeshi Muneta
    Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Arthroscopy 23:618-28. 2007
    ..A randomized clinical study was conducted to compare the outcome between double-bundle (DB) and single-bundle (SB) anterior cruciate ligament (ACL) reconstructions with 4-strand semitendinosus tendon (ST)...
  21. doi request reprint Intraarticular injection of synovial stem cells promotes meniscal regeneration in a rabbit massive meniscal defect model
    Daisuke Hatsushika
    Department of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Bunkyo ku, Japan
    J Orthop Res 31:1354-9. 2013
    ..Synovial MSCs injected into the knee adhered around the meniscal defect, and promoted meniscal regeneration in rabbits...
  22. doi request reprint Radiographic description of femoral tunnel placement expressed as intercondylar clock time in double-bundle anterior cruciate ligament reconstruction
    Junya Yamazaki
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital, Tokyo, Japan
    Knee Surg Sports Traumatol Arthrosc 19:418-23. 2011
    ..The reproducibility of the method was evaluated in double-bundle (DB) reconstructions...
  23. pmc Mesenchymal stem cells in synovial fluid increase after meniscus injury
    Yu Matsukura
    Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Clin Orthop Relat Res 472:1357-64. 2014
    ..Although relatively uncommon, spontaneous healing from a meniscus injury has been observed even within the avascular area. This may be the result of the existence of mesenchymal stem cells in synovial fluid...
  24. doi request reprint Transplantation of aggregates of synovial mesenchymal stem cells regenerates meniscus more effectively in a rat massive meniscal defect
    Hiroki Katagiri
    Department of Joint Surgery and Sports Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Biochem Biophys Res Commun 435:603-9. 2013
    ..We confirmed that MSCs transplanted as aggregates existed in the regenerated meniscus focally and partially. Transplantation of aggregates of synovial MSCs regenerated meniscus more effectively in a rat massive meniscal defect...
  25. pmc Arthroscopic centralization of an extruded lateral meniscus
    Hideyuki Koga
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan
    Arthrosc Tech 1:e209-12. 2012
    ..The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus...
  26. doi request reprint Hyaluronan injection therapy for athletic patients with patellar tendinopathy
    Takeshi Muneta
    Department of Orthopaedic Surgery, School of Medicine, Tokyo Medical and Dental University Hospital, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    J Orthop Sci 17:425-31. 2012
    ..The purpose of this study was to summarize the clinical experience of and to describe the appropriate indication for this injection therapy...
  27. ncbi request reprint Comparison of rat mesenchymal stem cells derived from bone marrow, synovium, periosteum, adipose tissue, and muscle
    Hideya Yoshimura
    Section of Orthopaedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Cell Tissue Res 327:449-62. 2007
    ..In particular, synovium-derived cells had the greatest potential for both proliferation and chondrogenesis, indicating their usefulness for cartilage study in a rat model...
  28. doi request reprint The kinematic analysis of female subjects after double-bundle anterior cruciate ligament reconstruction during single-leg squatting
    Junya Yamazaki
    Section of Orthopedic Surgery, School of Medicine, Tokyo Medical and Dental University Hospital, 1 5 45 Yushima, Bunkyo ku, Tokyo 113 8519, Japan
    J Orthop Sci 18:284-9. 2013
    ....
  29. doi request reprint Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium-derived mesenchymal stem cells
    Yoichi Ezura
    Department of Molecular Pharmacology, Tokyo Medical and Dental University, Tokyo, Japan
    Arthritis Rheum 60:1416-26. 2009
    ..The purpose of this study was to investigate the CpG methylation status in human synovium-derived MSCs during experimental chondrogenesis, with a view toward potential therapeutic use in osteoarthritis...
  30. ncbi request reprint Higher chondrogenic potential of fibrous synovium- and adipose synovium-derived cells compared with subcutaneous fat-derived cells: distinguishing properties of mesenchymal stem cells in humans
    Tomoyuki Mochizuki
    Tokyo Medical and Dental University, Yushima, Tokyo, Japan
    Arthritis Rheum 54:843-53. 2006
    ....
  31. ncbi request reprint Protein-conjugated quantum dots effectively delivered into living cells by a cationic nanogel
    Sayaka Toita
    Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2 3 10, Kanda Surugadai, Chiyoda ku, Tokyo 101 0062, Japan
    J Nanosci Nanotechnol 8:2279-85. 2008
    ..The hybrid nanoparticles are a promising candidate as a cell tracer in tissue engineering...
  32. pmc Effects of different initial bundle tensioning strategies on the outcome of double-bundle ACL reconstruction: a cohort study
    Takeshi Muneta
    Department of Orthopaedic Surgery, Tokyo Medical and Dental University Hospital, Tokyo, Japan
    Sports Med Arthrosc Rehabil Ther Technol 3:15. 2011
    ..abstract:..