Koji Kasahara

Summary

Affiliation: Tokyo University of Agriculture
Country: Japan

Publications

  1. pmc Hmo1 directs pre-initiation complex assembly to an appropriate site on its target gene promoters by masking a nucleosome-free region
    Koji Kasahara
    Division of Molecular and Cellular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama 230 0045, Japan
    Nucleic Acids Res 39:4136-50. 2011
  2. pmc Genome-wide localization analysis of a complete set of Tafs reveals a specific effect of the taf1 mutation on Taf2 occupancy and provides indirect evidence for different TFIID conformations at different promoters
    Kazushige Ohtsuki
    Division of Molecular and Cellular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama 230 0045, Japan
    Nucleic Acids Res 38:1805-20. 2010
  3. pmc Saccharomyces cerevisiae HMO1 interacts with TFIID and participates in start site selection by RNA polymerase II
    Koji Kasahara
    Division of Molecular and Cellular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, 230 0045, Japan
    Nucleic Acids Res 36:1343-57. 2008
  4. pmc Assembly of regulatory factors on rRNA and ribosomal protein genes in Saccharomyces cerevisiae
    Koji Kasahara
    Division of Molecular and Cellular Biology, Science of Supramolecular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, Kanagawa, Japan
    Mol Cell Biol 27:6686-705. 2007
  5. ncbi request reprint In vivo synthesis of Taf1p lacking the TAF N-terminal domain using alternative transcription or translation initiation sites
    Koji Kasahara
    Division of Molecular and Cellular Biology, Graduate School of Integrated Science, Yokohama City University, 230 0045, Japan
    Genes Cells 9:709-21. 2004
  6. doi request reprint Saccharomyces cerevisiae Med9 comprises two functionally distinct domains that play different roles in transcriptional regulation
    Hiroyuki Takahashi
    Division of Molecular and Cellular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama 230 0045, Japan
    Genes Cells 14:53-67. 2009
  7. pmc Autonomous function of the amino-terminal inhibitory domain of TAF1 in transcriptional regulation
    Shinya Takahata
    Division of Molecular and Cellular Biology, Graduate School of Integrated Science, Yokohama City University, Yokohama 230 0045, Japan
    Mol Cell Biol 24:3089-99. 2004
  8. ncbi request reprint Magnetic resonance-based visualization of gene expression in mammalian cells using a bacterial polyphosphate kinase reporter gene
    Sewon Ki
    Yokohama City University, Yokohama, Japan
    Biotechniques 42:209-15. 2007
  9. pmc A novel magnetic resonance-based method to measure gene expression in living cells
    Sewon Ki
    International Graduate School of Arts and Sciences, Yokohama City University, Yokohama 230 0045, Japan
    Nucleic Acids Res 34:e51. 2006
  10. pmc Highly redundant function of multiple AT-rich sequences as core promoter elements in the TATA-less RPS5 promoter of Saccharomyces cerevisiae
    Fuminori Sugihara
    Division of Molecular and Cellular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, Japan
    Nucleic Acids Res 39:59-75. 2011

Collaborators

Detail Information

Publications12

  1. pmc Hmo1 directs pre-initiation complex assembly to an appropriate site on its target gene promoters by masking a nucleosome-free region
    Koji Kasahara
    Division of Molecular and Cellular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama 230 0045, Japan
    Nucleic Acids Res 39:4136-50. 2011
    ..This novel mechanism ensures accurate transcriptional initiation by delineating the 5'- and 3'-boundaries of the PIC assembly zone...
  2. pmc Genome-wide localization analysis of a complete set of Tafs reveals a specific effect of the taf1 mutation on Taf2 occupancy and provides indirect evidence for different TFIID conformations at different promoters
    Kazushige Ohtsuki
    Division of Molecular and Cellular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama 230 0045, Japan
    Nucleic Acids Res 38:1805-20. 2010
    ....
  3. pmc Saccharomyces cerevisiae HMO1 interacts with TFIID and participates in start site selection by RNA polymerase II
    Koji Kasahara
    Division of Molecular and Cellular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, 230 0045, Japan
    Nucleic Acids Res 36:1343-57. 2008
    ....
  4. pmc Assembly of regulatory factors on rRNA and ribosomal protein genes in Saccharomyces cerevisiae
    Koji Kasahara
    Division of Molecular and Cellular Biology, Science of Supramolecular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, Kanagawa, Japan
    Mol Cell Biol 27:6686-705. 2007
    ..Reporter gene assays indicate that these functional properties are determined by the promoter sequence...
  5. ncbi request reprint In vivo synthesis of Taf1p lacking the TAF N-terminal domain using alternative transcription or translation initiation sites
    Koji Kasahara
    Division of Molecular and Cellular Biology, Graduate School of Integrated Science, Yokohama City University, 230 0045, Japan
    Genes Cells 9:709-21. 2004
    ..Finally, this study also demonstrates that Drosophila TAND2 substitutes functionally for yeast TAND2, but Drosophila TAND1 does not substitute for yeast TAND1...
  6. doi request reprint Saccharomyces cerevisiae Med9 comprises two functionally distinct domains that play different roles in transcriptional regulation
    Hiroyuki Takahashi
    Division of Molecular and Cellular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Yokohama 230 0045, Japan
    Genes Cells 14:53-67. 2009
    ..Add-back experiments indicate that some unidentified factor(s) in med9 extracts may impact the binding of TFIID to the promoter...
  7. pmc Autonomous function of the amino-terminal inhibitory domain of TAF1 in transcriptional regulation
    Shinya Takahata
    Division of Molecular and Cellular Biology, Graduate School of Integrated Science, Yokohama City University, Yokohama 230 0045, Japan
    Mol Cell Biol 24:3089-99. 2004
    ..These results indicate that there is no or minimal geometric constraint on the ability of the TAND to function normally in transcriptional regulation as long as TFIID assembly is secured...
  8. ncbi request reprint Magnetic resonance-based visualization of gene expression in mammalian cells using a bacterial polyphosphate kinase reporter gene
    Sewon Ki
    Yokohama City University, Yokohama, Japan
    Biotechniques 42:209-15. 2007
    ..The ppk reporter gene system described here is noninvasive, does not require an exogenous substrate, and can potentially be used in internal tissues of living organisms...
  9. pmc A novel magnetic resonance-based method to measure gene expression in living cells
    Sewon Ki
    International Graduate School of Arts and Sciences, Yokohama City University, Yokohama 230 0045, Japan
    Nucleic Acids Res 34:e51. 2006
    ..Because this system is completely non-invasive and does not require exogenous substrates, it is a powerful tool for studying gene expression in multicellular organisms, as well...
  10. pmc Highly redundant function of multiple AT-rich sequences as core promoter elements in the TATA-less RPS5 promoter of Saccharomyces cerevisiae
    Fuminori Sugihara
    Division of Molecular and Cellular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, Japan
    Nucleic Acids Res 39:59-75. 2011
    ..These results show a novel architecture of yeast TATA-less promoters and support a model in which pol II scans DNA downstream from a recruited site, while searching for appropriate initiation site(s)...
  11. doi request reprint Saccharomyces cerevisiae Ssd1p promotes CLN2 expression by binding to the 5'-untranslated region of CLN2 mRNA
    Yoshifumi Ohyama
    Division of Molecular and Cellular Biology, Department of Supramolecular Biology, Graduate School of Nanobioscience, Yokohama City University, 1 7 29, Suehiro cho, Tsurumi ku, Yokohama 230 0045, Japan
    Genes Cells 15:1169-88. 2010
    ..Based on these observations, we propose a model for the action of Ssd1p and discuss its biologic role...
  12. ncbi request reprint Identification of a novel TATA element-binding protein binding region at the N terminus of the Saccharomyces cerevisiae TAF1 protein
    Shinya Takahata
    Division of Molecular and Cellular Biology, Graduate School of Integrated Science, Yokohama City University, Yokohama 230 0045, USA
    J Biol Chem 278:45888-902. 2003
    ..Supporting these observations is that TAND1 can be at least partly functionally substituted by TAND3...