Hideki Ishikawa

Summary

Affiliation: Tokyo Women's Medical University
Country: Japan

Publications

  1. ncbi request reprint Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention and Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Japan
    J Nutr 136:816S-820S. 2006
  2. ncbi request reprint Randomized controlled trial of the effect of bifidobacteria-fermented milk on ulcerative colitis
    Hideki Ishikawa
    Department of Cancer Epidemiology, Research Institute, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    J Am Coll Nutr 22:56-63. 2003
  3. doi request reprint Beneficial effects of probiotic bifidobacterium and galacto-oligosaccharide in patients with ulcerative colitis: a randomized controlled study
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Digestion 84:128-33. 2011
  4. ncbi request reprint Randomized trial of dietary fiber and Lactobacillus casei administration for prevention of colorectal tumors
    Hideki Ishikawa
    Laboratory of Hereditary Tumors, Institute for Advanced Medical Sciences, Hyogo College of Medicine, Osaka, Japan
    Int J Cancer 116:762-7. 2005
  5. ncbi request reprint Chemoprevention of carcinogenesis in familial tumors
    Hideki Ishikawa
    Laboratory of Hereditary Tumor, Institute for Advanced Medical Sciences, Hyogo College of Medicine, 2 3 1 2F Kyomachibori, Nishi ku, 550 0003, Osaka, Japan
    Int J Clin Oncol 9:299-303. 2004
  6. doi request reprint Excessive fat restriction might promote the recurrence of colorectal tumors
    Tomiyo Nakamura
    Osaka University Graduate School of Medicine and Health Science, Osaka, Japan
    Nutr Cancer 62:154-63. 2010
  7. ncbi request reprint [Prevention of carcinogenesis in familial tumors]
    Hideki Ishikawa
    Dept of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Osaka, Japan
    Gan To Kagaku Ryoho 32:973-6. 2005
  8. ncbi request reprint A pilot, randomized, placebo-controlled, double-blind phase 0/biomarker study on effect of artepillin C-rich extract of Brazilian propolis in frequent colorectal adenoma polyp patients
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Am Coll Nutr 31:327-37. 2012
  9. pmc Preventive effects of low-dose aspirin on colorectal adenoma growth in patients with familial adenomatous polyposis: double-blind, randomized clinical trial
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kyoto, Japan
    Cancer Med 2:50-6. 2013
  10. doi request reprint Chemoprevention of colorectal cancer in Japan: a brief introduction to current clinical trials
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, 3 2 17 Imahashi, Chuo Ku, Osaka, 541 0042, Japan
    J Gastroenterol 44:77-81. 2009

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention and Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Japan
    J Nutr 136:816S-820S. 2006
    ..No adverse effect was observed in either group. The study showed that administering AGE to patients with advanced cancer of the digestive system improved NK cell activity, but caused no improvement in QOL...
  2. ncbi request reprint Randomized controlled trial of the effect of bifidobacteria-fermented milk on ulcerative colitis
    Hideki Ishikawa
    Department of Cancer Epidemiology, Research Institute, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    J Am Coll Nutr 22:56-63. 2003
    ..Alterations of intestinal flora, such as reduction in the concentration of bifidobacteria and increase in that of Bacteroides species, are apparently associated with the severity of ulcerative colitis...
  3. doi request reprint Beneficial effects of probiotic bifidobacterium and galacto-oligosaccharide in patients with ulcerative colitis: a randomized controlled study
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Digestion 84:128-33. 2011
    ..Here, we examined the effects of a live Bifidobacterium breve strain Yakult, a probiotic contained in bifidobacteria-fermented milk, and galacto-oligosaccharide (GOS) as synbiotics in UC patients...
  4. ncbi request reprint Randomized trial of dietary fiber and Lactobacillus casei administration for prevention of colorectal tumors
    Hideki Ishikawa
    Laboratory of Hereditary Tumors, Institute for Advanced Medical Sciences, Hyogo College of Medicine, Osaka, Japan
    Int J Cancer 116:762-7. 2005
    ..casei. No significant difference in the development of new colorectal tumors was observed with administration of either wheat bran or L. casei. However, our results suggest that L. casei prevented atypia of colorectal tumors...
  5. ncbi request reprint Chemoprevention of carcinogenesis in familial tumors
    Hideki Ishikawa
    Laboratory of Hereditary Tumor, Institute for Advanced Medical Sciences, Hyogo College of Medicine, 2 3 1 2F Kyomachibori, Nishi ku, 550 0003, Osaka, Japan
    Int J Clin Oncol 9:299-303. 2004
    ..In addition to NSAIDs, clinical trials have been performed using vitamins and dietary components. These show minimal side effects, but their efficacy is still insufficient for clinical use, and further studies are anticipated...
  6. doi request reprint Excessive fat restriction might promote the recurrence of colorectal tumors
    Tomiyo Nakamura
    Osaka University Graduate School of Medicine and Health Science, Osaka, Japan
    Nutr Cancer 62:154-63. 2010
    ..For women, similar trends were observed. These results suggest that extreme fat restriction is highly likely to promote the recurrence of colorectal tumors, which may be partly attributable to linoleic acid deficiency...
  7. ncbi request reprint [Prevention of carcinogenesis in familial tumors]
    Hideki Ishikawa
    Dept of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Osaka, Japan
    Gan To Kagaku Ryoho 32:973-6. 2005
    ..In addition to NSAIDs, clinical trials have been performed using vitamins and dietary components. These show minimal side effects, but their efficacy is still insufficient for clinical use, and further studies are anticipated...
  8. ncbi request reprint A pilot, randomized, placebo-controlled, double-blind phase 0/biomarker study on effect of artepillin C-rich extract of Brazilian propolis in frequent colorectal adenoma polyp patients
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan
    J Am Coll Nutr 31:327-37. 2012
    ..The objective of the study was to test in a small pilot biomarker study in a high-risk group the safety and efficacy of propolis for colon cancer prevention, which has not been evaluated in humans...
  9. pmc Preventive effects of low-dose aspirin on colorectal adenoma growth in patients with familial adenomatous polyposis: double-blind, randomized clinical trial
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Kyoto, Japan
    Cancer Med 2:50-6. 2013
    ..The results thus indicated a potential for aspirin to reduce colorectal adenoma development in patients with FAP, but careful follow-up is needed to avoid or rapidly counter severe adverse effects...
  10. doi request reprint Chemoprevention of colorectal cancer in Japan: a brief introduction to current clinical trials
    Hideki Ishikawa
    Department of Molecular Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, 3 2 17 Imahashi, Chuo Ku, Osaka, 541 0042, Japan
    J Gastroenterol 44:77-81. 2009
    ..This article outlines relevant past clinical data and gives a brief introduction to these two studies...
  11. ncbi request reprint Significance of fecal deoxycholic acid concentration for colorectal tumor enlargement
    Atsuko Kawano
    Division of Preventive and Social Medicine, Department of Hygiene and Public Health, Osaka Medical College
    Asian Pac J Cancer Prev 11:1541-6. 2010
    ..85, 95% confidence interval: 1.12-3.05). This trend was observed more strongly in the left side colon. In conclusion, a high fecal DCA concentration may be a promoter of colorectal tumor enlargement...
  12. ncbi request reprint Aged garlic extract inhibits angiogenesis and proliferation of colorectal carcinoma cells
    Nariaki Matsuura
    Department of Molecular Targeting Cancer Prevention and Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Osaka, Japan
    J Nutr 136:842S-846S. 2006
    ..AGE would be a good chemopreventive agent for colorectal cancer because of its antiproliferative action on colorectal carcinoma cells and inhibitory activity on angiogenesis...
  13. ncbi request reprint Reduction in salivary cortisol level by music therapy during colonoscopic examination
    Noriya Uedo
    Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan
    Hepatogastroenterology 51:451-3. 2004
    ..Music therapy is widely used in the treatment of acute and chronic pain. Therefore, we investigated the effects of music therapy on pain and on salivary cortisol levels in patients undergoing screening colonoscopy...
  14. doi request reprint Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation
    Momoko Todo
    Department of Molecular Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi Hirokoji, Kamigyo ku, Kyoto 602 8566, Japan
    Oncol Rep 30:2379-84. 2013
    ....
  15. ncbi request reprint Familial adenomatous polyposis complicated by chronic myelogenous leukemia: response to imatinib mesylate
    Takeyoshi Itsukuma
    Division of Hematology Oncology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
    J Gastroenterol 42:402-5. 2007
    ..Eighteen months later, however, the polyps were enlarged. In this patient, imatinib administration led to the remission of CML and might also have been responsible for the temporary regression of adenomatous polyps of FAP...
  16. ncbi request reprint [Cancer prevention in familial cancer]
    Hideki Ishikawa
    Department of Cancer Epidemiology, Osaka Medical Center for Cancer and Cardiovascular Diseases, 3 3 Nakamichi, 1 chome, Higashinari ku, Osaka 537 8511, Japan
    Gan To Kagaku Ryoho 29:545-9. 2002
    ..The main end point of the trial is number and size of colorectal adenomas after 2 years. Subject recruiting was started in March, 2002. The trial will be completed in September, 2005...
  17. ncbi request reprint Evaluation of epidemiological studies of intestinal bacteria that affected occurrence of colorectal cancer: studies of prevention of colorectal tumors by dairy products and lactic acid bacteria
    Atsuko Kawano
    Division of Preventive and Social Medicine, Department of Hygiene and Public Health, Osaka Medical College
    Nihon Eiseigaku Zasshi 65:422-46. 2010
    ..On the other hand, it was suggested in some clinical studies that lactic acid bacteria reduce the occurrence of colorectal cancer...
  18. ncbi request reprint [Investigation of the Giardia lamblia infection rate using whole gut lavage fluid]
    Astuko Kawano
    Division of Preventive and Social Medicine, Department of Hygiene and Public Health, Osaka Medical College
    Nihon Shokakibyo Gakkai Zasshi 105:1605-11. 2008
    ..We investigated the presence of trophozoites of Giardia lamblia microscopically in sediment of whole gut lavage fluid obtained from patients undergoing colonoscopy...
  19. ncbi request reprint Aged garlic extract has chemopreventative effects on 1,2-dimethylhydrazine-induced colon tumors in rats
    Takefumi Katsuki
    Department of Surgery 1, University of Occupational and Environmental Health, Kitakyushu, Japan
    J Nutr 136:847S-851S. 2006
    ..AGE treatment significantly decreased the mean MIB-5-labeling index. These findings suggest AGE has a chemopreventive effect on colon carcinogenesis through suppression of cell proliferation...
  20. ncbi request reprint Elevated risk of colorectal cancer associated with the AA genotype of the cyclin D1 A870G polymorphism in an Indian population
    Jing Jiang
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, 467 8601 Nagoya, Japan
    J Cancer Res Clin Oncol 132:193-9. 2006
    ..To investigate whether the common cyclin D1 (CCND1) A870G polymorphism is a risk factor for colorectal cancer (CRC) in an Indian population...
  21. ncbi request reprint Efficacy of cyclosporin with corticotropin for refractory ulcerative colitis
    Shozo Okamura
    Division of Gastroenterology, Department of Internal Medicine Toyohashi, Municipal Hospital, Aotake cho, Toyohashi, Aichi, 441 8570, Japan
    Hepatogastroenterology 50:91-4. 2003
    ..Our aim was to assess the short- and long-term efficacy of combination therapy with cyclosporin and corticotropin for steroid-resistant ulcerative colitis...
  22. ncbi request reprint Prevention of gut inflammation by Bifidobacterium in dextran sulfate-treated gnotobiotic mice associated with Bacteroides strains isolated from ulcerative colitis patients
    Hiromi Setoyama
    Yakult Central Institute for Microbiological Research, Yaho 1796, Kunitachi shi, Tokyo 186 8650, Japan
    Microbes Infect 5:115-22. 2003
    ..vulgatus strain, and that Bifidobacterium strains may repress exacerbation of intestinal inflammation through growth inhibition of the B. vulgatus strain...
  23. ncbi request reprint A comparison of image quality between tissue harmonic imaging and fundamental imaging with an electronic radial scanning echoendoscope in the diagnosis of pancreatic diseases
    Hideki Ishikawa
    Second Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Japan
    Gastrointest Endosc 57:931-6. 2003
    ..This study compares the quality of US images acquired by tissue harmonic imaging during electronic radial scanning EUS to those acquired by fundamental imaging...
  24. ncbi request reprint Case of intraductal papillary mucinous tumor in which endosonography-guided fine-needle aspiration biopsy caused dissemination
    Yoshiki Hirooka
    J Gastroenterol Hepatol 18:1323-4. 2003
  25. ncbi request reprint Comparison of image quality between electronic and mechanical radial scanning echoendoscopes in pancreatic diseases
    Katsushi Niwa
    Second Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Japan
    J Gastroenterol Hepatol 19:454-9. 2004
    ..In 2000, a newly designed echoendoscope, the electronic radial scanning echoendoscope (ER-ES), appeared. The aim of the present study was to compare B-mode image quality between the ER-ES and the MR-ES in pancreatic diseases...
  26. ncbi request reprint The novel germline mutation of the hMLH1 gene in a case of suspected hereditary non-polyposis colorectal cancer (HNPCC) in a patient with no family history of cancer
    Naohiro Tomita
    Department of Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo 660 8511, Japan
    Jpn J Clin Oncol 34:556-60. 2004
    ..According to the Human Mutation Database and International Collaborative Group on HNPCC (ICG-HNPCC) Database, this is the first report of this type of deletion mutation in the hMLH1 gene...
  27. ncbi request reprint Influence of the C161T but not Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma on colorectal cancer in an Indian population
    Jing Jiang
    Department of Health Promotion and Preventive Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho ku, Nagoya 467 8601, Japan
    Cancer Sci 96:507-12. 2005
    ..Further research is needed to investigate functional implications of polymorphisms of the PPAR-gamma gene in CRC development...
  28. ncbi request reprint Associations between 5,10-methylenetetrahydrofolate reductase codon 677 and 1298 genetic polymorphisms and environmental factors with reference to susceptibility to colorectal cancer: a case-control study in an Indian population
    Jingwen Wang
    Department of Health Promotion and Preventive Medicine, Nagoya City University, Graduate School of Medical Sciences, Nagoya, Japan
    Int J Cancer 118:991-7. 2006
    ..55, 95% CI 0.73-3.33), were at a somewhat higher rectal cancer risk. Moreover, the consumed alcohol amount (gram-years) may be also associated with colon or rectal cancer risk...
  29. ncbi request reprint Cholecystocolonic fistula preoperatively diagnosed by endoscopic ultrasound of the colon
    Naoto Okada
    Department of Gastroenterology, Nagoya University School of Medicine, Nagoya, Japan
    J Gastroenterol Hepatol 20:1621-4. 2005
    ..Barium enema and endoscopic retrograde cholangiopancreatography did not reveal fistula. Curved-linear array EUS of the colon showed fistula...
  30. ncbi request reprint [Cancer prevention]
    Hideyuki Akaza
    Dept of Urology, Institute of Clinical Medicine, University of Tsukuba
    Gan To Kagaku Ryoho 32:1499-506. 2005
    ..Overall, cancer prevention is still in evolution. New approaches are needed, and new infrastructure will be needed at a government level to implement this...