K Ikari

Summary

Affiliation: Tokyo Women's Medical University
Country: Japan

Publications

  1. pmc Supportive evidence for a genetic association of the FCRL3 promoter polymorphism with rheumatoid arthritis
    K Ikari
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Ann Rheum Dis 65:671-3. 2006
  2. pmc ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population
    Noriko Iikuni
    Arthritis Res Ther 9:405. 2007
  3. ncbi request reprint Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population
    K Ikari
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Tokyo 162 0054, Japan
    Rheumatology (Oxford) 45:1345-8. 2006
  4. ncbi request reprint Association between PADI4 and rheumatoid arthritis: a replication study
    Katsunori Ikari
    Institute of Rheumatology, Tokyo Women s Medical University, Kwada, Tokyo, Japan
    Arthritis Rheum 52:3054-7. 2005
  5. ncbi request reprint Effect of matrix metalloproteinase-3 functional SNP on serum matrix metalloproteinase-3 level and outcome measures in Japanese RA patients
    S Tsukahara
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Rheumatology (Oxford) 47:41-4. 2008
  6. ncbi request reprint Association between PADI4 and rheumatoid arthritis: a meta-analysis
    T Iwamoto
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Rheumatology (Oxford) 45:804-7. 2006
  7. doi request reprint Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese
    K Nishimoto
    Institute of Rheumatology, Tokyo Women s Medical University, Japan
    Ann Rheum Dis 69:368-73. 2010
  8. doi request reprint Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population
    Shu Kobayashi
    Tokyo Women s Medical University, Tokyo, Japan
    Arthritis Rheum 58:1940-6. 2008
  9. ncbi request reprint Failure to confirm association between SLC22A4 polymorphism and rheumatoid arthritis in a Japanese population
    Mahito Kuwahara
    Institute of Rheumatology, Tokyo Women s Medical University, Tokyo, Japan
    Arthritis Rheum 52:2947-8. 2005
  10. doi request reprint Association of the MSX2 gene polymorphisms with ankylosing spondylitis in Japanese
    Tatsuya Furuichi
    Laboratory for Bone and Joint Diseases, SNP Research Center, RIKEN, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    J Hum Genet 53:419-24. 2008

Collaborators

Detail Information

Publications27

  1. pmc Supportive evidence for a genetic association of the FCRL3 promoter polymorphism with rheumatoid arthritis
    K Ikari
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Ann Rheum Dis 65:671-3. 2006
    ..A case-control study showed that the strongest evidence of the association was derived from a polymorphism in the promoter region of FCRL3, which has a regulatory effect on the expression of the gene...
  2. pmc ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population
    Noriko Iikuni
    Arthritis Res Ther 9:405. 2007
  3. ncbi request reprint Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population
    K Ikari
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Tokyo 162 0054, Japan
    Rheumatology (Oxford) 45:1345-8. 2006
    ..Because the gene confers an impact on autoimmune diseases, we attempt to explore an association between PTPN22 gene and RA in a Japanese population without restricting to the SNP, R620W...
  4. ncbi request reprint Association between PADI4 and rheumatoid arthritis: a replication study
    Katsunori Ikari
    Institute of Rheumatology, Tokyo Women s Medical University, Kwada, Tokyo, Japan
    Arthritis Rheum 52:3054-7. 2005
    ..The present study was undertaken to further investigate the association of PADI4 with RA, using a series of population-based samples from subjects with the same ethnic background as the subjects in the original study...
  5. ncbi request reprint Effect of matrix metalloproteinase-3 functional SNP on serum matrix metalloproteinase-3 level and outcome measures in Japanese RA patients
    S Tsukahara
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Rheumatology (Oxford) 47:41-4. 2008
    ..We attempt to determine whether the MMP-3 promoter polymorphism is associated with serum titre of MMP-3, disease activity and severity in Japanese RA patients...
  6. ncbi request reprint Association between PADI4 and rheumatoid arthritis: a meta-analysis
    T Iwamoto
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Rheumatology (Oxford) 45:804-7. 2006
    ..However, subsequent replication studies showed conflicting results. The aim of this study was to determine whether meta-analysis would prove the existence of the association...
  7. doi request reprint Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese
    K Nishimoto
    Institute of Rheumatology, Tokyo Women s Medical University, Japan
    Ann Rheum Dis 69:368-73. 2010
    ..Gene expression levels of TRAF1 and C5 to assess the functional significance of genotypes were also analysed...
  8. doi request reprint Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population
    Shu Kobayashi
    Tokyo Women s Medical University, Tokyo, Japan
    Arthritis Rheum 58:1940-6. 2008
    ..The present study was undertaken to investigate the effect of STAT4 on susceptibility to RA and SLE in the Japanese...
  9. ncbi request reprint Failure to confirm association between SLC22A4 polymorphism and rheumatoid arthritis in a Japanese population
    Mahito Kuwahara
    Institute of Rheumatology, Tokyo Women s Medical University, Tokyo, Japan
    Arthritis Rheum 52:2947-8. 2005
  10. doi request reprint Association of the MSX2 gene polymorphisms with ankylosing spondylitis in Japanese
    Tatsuya Furuichi
    Laboratory for Bone and Joint Diseases, SNP Research Center, RIKEN, 4 6 1 Shirokanedai, Minato ku, Tokyo 108 8639, Japan
    J Hum Genet 53:419-24. 2008
    ..In the genes previously reported to have association with AS, only one synonymous SNP, c.963T > G in ANKH, showed a marginal association in the Japanese population (P = 0.045)...
  11. pmc MHC2TA is associated with rheumatoid arthritis in Japanese patients
    Noriko Iikuni
    Ann Rheum Dis 66:274-5. 2007
  12. ncbi request reprint Risk factors for total knee arthroplasty in rheumatoid arthritis
    Shigeki Momohara
    Department of Orthopaedic Surgery, Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku ku, Tokyo, 162 0054, Japan
    Mod Rheumatol 17:476-80. 2007
    ..These results suggest that, when treating RA patients, physicians should pay particular attention to pain complaints, the patient's daily activity level, and the RF factor status...
  13. ncbi request reprint Dermatan sulfate in the synovial fluid of patients with knee osteoarthritis
    Shigeki Momohara
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku ku, Tokyo, 162 0054, Japan
    Mod Rheumatol 17:301-5. 2007
    ..This suggests that metabolism of the small leucine-rich repeat proteoglycans decorin and biglycan, which contain chains of DSDeltaDi4S, is similar to that of aggrecan...
  14. ncbi request reprint Linkage and association analyses of the osteoprotegerin gene locus with human osteoporosis
    Hioryuki Ohmori
    Department of Public Health, Asahikawa Medical College, 2 1 1 1 Midorigaoka Higashi, Asahikawa 078 8510, Japan
    J Hum Genet 47:400-6. 2002
    ..A haplotype analysis with the six SNPs revealed that four major haplotypes account for 71% of the alleles in the Japanese population...
  15. ncbi request reprint High CCL18/PARC expression in articular cartilage and synovial tissue of patients with rheumatoid arthritis
    Shigeki Momohara
    Institute of Rheumatology, Tokyo Women s Medical University, Tokyo, Japan
    J Rheumatol 34:266-71. 2007
    ..We studied the role of CCL18/pulmonary and activation-regulated chemokine (PARC) in rheumatoid arthritis (RA)...
  16. ncbi request reprint Failure to confirm association between PDCD1 polymorphisms and rheumatoid arthritis in a Japanese population
    Takuji Iwamoto
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo, 162 0054, Japan
    J Hum Genet 52:557-60. 2007
    ..We conclude that polymorphisms in the PDCD1 gene analyzed here are not associated with RA in a Japanese population...
  17. doi request reprint Return of infliximab efficacy after total knee arthroplasty in a patient with rheumatoid arthritis
    Hiroe Toki
    Clin Rheumatol 27:549-50. 2008
  18. ncbi request reprint A case of Castleman's disease associated with diffuse idiopathic skeletal hyperostosis and ossification of the posterior longitudinal ligament of the spine
    Shu Kobayashi
    Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku ku, Tokyo, 162 0054, Japan
    Mod Rheumatol 17:418-21. 2007
    ..In this paper, we describe this patient in order to discuss the association of these diseases...
  19. ncbi request reprint A role of monocyte chemoattractant protein-4 (MCP-4)/CCL13 from chondrocytes in rheumatoid arthritis
    Takuji Iwamoto
    Institute of Rheumatology, Tokyo Women s Medical University, Japan
    FEBS J 274:4904-12. 2007
    ....
  20. ncbi request reprint Disturbances of the symphysis pubis in rheumatoid arthritis: report of two cases
    So Tsukahara
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku ku, Tokyo, 162 0054, Japan
    Mod Rheumatol 17:344-7. 2007
    ..Both cases had received long-term corticosteroid therapy, including pulse therapy. We recommend reducing the corticosteroid dose to prevent disturbances of the symphysis pubis especially in RA patients on long-term steroid therapy...
  21. ncbi request reprint The serum concentration of infliximab in cases of autologous blood donation for patients with rheumatoid arthritis
    Takeshi Mochizuki
    Department of Orthopaedic Surgery, Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Tokyo 162 0054, Japan
    Mod Rheumatol 17:24-7. 2007
    ..However, even after autotransfusion those levels were decreased compared with levels measured just before the operation. Therefore, we conclude that there is little influence of AB donation on the risks of infliximab...
  22. ncbi request reprint Spontaneous multiple insufficiency fractures after pelvic abscess and sepsis in a rheumatoid arthritis patient treated with high-load corticosteroid therapy: a case report
    Takeshi Mochizuki
    Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo, 162 0054, Japan
    Clin Rheumatol 26:1925-8. 2007
    ....
  23. ncbi request reprint Acute destruction of the hip joints and rapid resorption of femoral head in patients with rheumatoid arthritis
    Koichiro Yoshino
    Department of Orthopedic Surgery, Institute of Rheumatology, Tokyo Women s Medical University, 10 22 Kawada, Shinjuku, Tokyo 162 0054, Japan
    Mod Rheumatol 16:395-400. 2006
    ..As a result, all of them had total hip arthroplasty. We recommend taking repetitive radiographs for RA patients with continuing severe hip pain...
  24. ncbi request reprint Images in clinical medicine. Bone changes in rheumatoid arthritis
    Katsunori Ikari
    Tokyo Women s Medical University, Tokyo 162 0054, Japan
    N Engl J Med 353:e13. 2005
  25. ncbi request reprint Matrix metalloproteinase 28/epilysin expression in cartilage from patients with rheumatoid arthritis and osteoarthritis: comment on the article by Kevorkian et al
    Shigeki Momohara
    Arthritis Rheum 50:4074-5; author reply 4075. 2004
  26. pmc Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine
    Toshihiro Tanaka
    Division of Genetic Diagnosis, The Institute of Medical Science, University of Tokyo, Tokyo, Japan
    Am J Hum Genet 73:812-22. 2003
    ..Identification of the locus of susceptibility to OPLL by genomewide linkage and linkage disequilibrium studies permits us to investigate the pathogenesis of the disease, which may lead to the development of novel therapeutic tools...
  27. ncbi request reprint Large-scale screening for candidate genes of ossification of the posterior longitudinal ligament of the spine
    Kozo Furushima
    Division of Genetic Diagnosis, The Institute of Medical Science The University of Tokyo, Japan
    J Bone Miner Res 17:128-37. 2002
    ..Only BMP4 reached criteria of suggestive evidence of linkage. Because this gene is a well-known factor in osteogenetic function, BMP4 should be screened in further study for the polymorphism responsible...