T Hisabori

Summary

Affiliation: Tokyo Institute of Technology
Country: Japan

Publications

  1. pmc Molecular processes of inhibition and stimulation of ATP synthase caused by the phytotoxin tentoxin
    Erik Meiss
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259 R1 8, Yokohama 226 8503, Japan
    J Biol Chem 283:24594-9. 2008
  2. ncbi request reprint Molecular devices of chloroplast F(1)-ATP synthase for the regulation
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, Yokohama, Kanagawa, Japan
    Biochim Biophys Acta 1555:140-6. 2002
  3. ncbi request reprint [Intelligent proteomics: requirement of new strategy]
    Toru Hisabori
    Tanpakushitsu Kakusan Koso 48:1263-8. 2003
  4. ncbi request reprint Thioredoxin affinity chromatography: a useful method for further understanding the thioredoxin network
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8503, Japan
    J Exp Bot 56:1463-8. 2005
  5. ncbi request reprint [ATP synthase: highly organized molecular structure and its marvelous function]
    Toru Hisabori
    Tanpakushitsu Kakusan Koso 50:1151-9. 2005
  6. ncbi request reprint Towards a functional dissection of thioredoxin networks in plant cells
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta, Midori ku, Yokohama, Japan
    Photochem Photobiol 83:145-51. 2007
  7. ncbi request reprint The gamma subunit in chloroplast F(1)-ATPase can rotate in a unidirectional and counter-clockwise manner
    T Hisabori
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama, Japan
    FEBS Lett 463:35-8. 1999
  8. ncbi request reprint The formation or the reduction of a disulfide bridge on the gamma subunit of chloroplast ATP synthase affects the inhibitory effect of the epsilon subunit
    T Hisabori
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8503, Japan
    J Biol Chem 273:15901-5. 1998
  9. ncbi request reprint The regulatory functions of the gamma and epsilon subunits from chloroplast CF1 are transferred to the core complex, alpha3beta3, from thermophilic bacterial F1
    T Hisabori
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Yokohama, Japan
    Eur J Biochem 247:1158-65. 1997
  10. ncbi request reprint Molecular evolution of the modulator of chloroplast ATP synthase: origin of the conformational change dependent regulation
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, and ATP System Project, Exploratory Research for Advanced Technology, Japan Science and Technology Corporation, Yokohama, Japan
    FEBS Lett 545:71-5. 2003

Collaborators

  • Y Kato
  • Tatsuru Masuda
  • Ken Motohashi
  • E Muneyuki
  • K Mochizuki
  • Dirk Bald
  • Y Kikuchi
  • Patrick G N Romano
  • Masasuke Yoshida
  • Georg Groth
  • Shinji Masuda
  • Fumihiko Fujii
  • Y Sugano
  • Fumio Arisaka
  • Hiroki Konno
  • Naomi Hosoya-Matsuda
  • Ken ichiro Takamiya
  • Hanayo Ueoka-Nakanishi
  • Holger Lill
  • Ei Ichiro Sunamura
  • Erik Meiss
  • Shoko Hishiya
  • Masahiro Wakita
  • Akinori Ikegami
  • Hiroyuki Ohta
  • Satoshi Hara
  • Yoshiki Yamaryo
  • Masayuki Ohmori
  • Hidehisa Yoshimura
  • Takayuki Suzuki
  • Penka Pavlova
  • Daisuke Yamazaki
  • Kenji Sugiyama
  • Yang Tian
  • K Y Hara
  • K Shiseki
  • Mari Imashimizu-Kobayashi
  • Wakako Hatakeyama
  • Masahiko Ikeuchi
  • Yoko Mizota
  • Shigekazu Takahashi
  • Naho Yoshimura
  • Naoki Fusada
  • Tomoe Murakami-Fuse
  • Chan Gi Pack
  • Nobuhiro Kikuchi
  • Fumie Koyama
  • Masataka Kinjo
  • Kazuhito Inoue
  • Akiko Nozaki
  • Toshiharu Suzuki
  • Yoichi Nakanishi
  • Katsuya Shimabukuro
  • Yukichi Hara
  • Takeshi Kasama
  • Shinjiro Kasahara
  • Takeyoshi Okajima
  • Takeo Ohsaka
  • Mieko Shioda
  • Lanqun Mao
  • N Murai
  • H Taguchi
  • F Motojima
  • Y Kato-Yamada

Detail Information

Publications37

  1. pmc Molecular processes of inhibition and stimulation of ATP synthase caused by the phytotoxin tentoxin
    Erik Meiss
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259 R1 8, Yokohama 226 8503, Japan
    J Biol Chem 283:24594-9. 2008
    ..Hence, tentoxin is a sophisticated molecular tool to mark and control certain catalytic steps within the reaction pathway of the molecular F1 motor...
  2. ncbi request reprint Molecular devices of chloroplast F(1)-ATP synthase for the regulation
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, Yokohama, Kanagawa, Japan
    Biochim Biophys Acta 1555:140-6. 2002
    ..In this article, we discuss recent progress in understanding of the regulation system of the chloroplast ATP synthase at the molecular level...
  3. ncbi request reprint [Intelligent proteomics: requirement of new strategy]
    Toru Hisabori
    Tanpakushitsu Kakusan Koso 48:1263-8. 2003
  4. ncbi request reprint Thioredoxin affinity chromatography: a useful method for further understanding the thioredoxin network
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8503, Japan
    J Exp Bot 56:1463-8. 2005
    ..Based on the information on the target proteins provided by these studies, the complete thioredoxin-related redox networks can now be efficiently described...
  5. ncbi request reprint [ATP synthase: highly organized molecular structure and its marvelous function]
    Toru Hisabori
    Tanpakushitsu Kakusan Koso 50:1151-9. 2005
  6. ncbi request reprint Towards a functional dissection of thioredoxin networks in plant cells
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta, Midori ku, Yokohama, Japan
    Photochem Photobiol 83:145-51. 2007
    ..The current review charts the technical progress made in the continuing discovery of the numerous and diverse roles played by these proteins in the regulation of redox networks in plant cells...
  7. ncbi request reprint The gamma subunit in chloroplast F(1)-ATPase can rotate in a unidirectional and counter-clockwise manner
    T Hisabori
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama, Japan
    FEBS Lett 463:35-8. 1999
    ..We conclude that the rotation of the gamma subunit in the F(1)-motor is a ubiquitous phenomenon in all F(1)-ATPases in prokaryotes as well as in eukaryotes...
  8. ncbi request reprint The formation or the reduction of a disulfide bridge on the gamma subunit of chloroplast ATP synthase affects the inhibitory effect of the epsilon subunit
    T Hisabori
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8503, Japan
    J Biol Chem 273:15901-5. 1998
    ..These results show that the formation or reduction of the disulfide bond on the gamma subunit may induce a conformational change in the region that directly affects the interaction of this subunit with the adjacent epsilon subunit...
  9. ncbi request reprint The regulatory functions of the gamma and epsilon subunits from chloroplast CF1 are transferred to the core complex, alpha3beta3, from thermophilic bacterial F1
    T Hisabori
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Yokohama, Japan
    Eur J Biochem 247:1158-65. 1997
    ....
  10. ncbi request reprint Molecular evolution of the modulator of chloroplast ATP synthase: origin of the conformational change dependent regulation
    Toru Hisabori
    Chemical Resources Laboratory, Tokyo Institute of Technology, and ATP System Project, Exploratory Research for Advanced Technology, Japan Science and Technology Corporation, Yokohama, Japan
    FEBS Lett 545:71-5. 2003
    ..In this review, we describe the function of two regulatory subunits, gamma and epsilon, of ATP synthase based on their possible conformational changes and discuss the evolutionary origin of these regulation systems...
  11. pmc Comprehensive survey of proteins targeted by chloroplast thioredoxin
    K Motohashi
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8503, Japan
    Proc Natl Acad Sci U S A 98:11224-9. 2001
    ..The method developed in the present study is thus applicable to investigate the various redox networks via Trxs and the related enzymes in the cell...
  12. ncbi request reprint Redox regulation of the rotation of F(1)-ATP synthase
    D Bald
    PRESTO, Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Japan
    J Biol Chem 276:39505-7. 2001
    ..These findings obtained by the single molecule analysis therefore provide new insights into the mechanisms of enzyme regulation...
  13. ncbi request reprint Conformational change of the chloroplast ATP synthase on the enzyme activation process detected by the trypsin sensitivity of the gamma subunit
    Kenji Sugiyama
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama 226 8503, Japan
    Biochem Biophys Res Commun 301:311-6. 2003
    ..From these results, we propose the Delta mu H(+)-dependent conformational change of CF(1) on the enzyme activation process, which is affected by both ADP binding to the catalytic sites and proton flow via F(o) portion...
  14. ncbi request reprint The heterogeneous interaction of substoichiometric TNP-ATP and F1-ATPase from Escherichia coli
    E Muneyuki
    Research Laboratory of Resources Utilization, Tokyo Institute of Technology, Yokohama
    J Biochem 120:940-5. 1996
    ..Weaker affinity of the catalytic site for TNP-ATP may account for the heterogeneous binding and hydrolysis under the conditions described in this paper...
  15. ncbi request reprint The role of the betaDELSEED motif of F1-ATPase: propagation of the inhibitory effect of the epsilon subunit
    K Y Hara
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama, 226-8503, Japan
    J Biol Chem 276:23969-73. 2001
    ..We here conclude that the epsilon subunit exerts its inhibitory effect through the electrostatic interaction with the DELSEED motif of the beta subunit...
  16. ncbi request reprint The CHLI1 subunit of Arabidopsis thaliana magnesium chelatase is a target protein of the chloroplast thioredoxin
    Akinori Ikegami
    Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama 226 8501, Japan
    J Biol Chem 282:19282-91. 2007
    ..Our findings strongly suggest that chlorophyll biosynthesis is subject to chloroplast biogenesis regulation networks to coordinate them with the photosynthetic pathways in chloroplasts...
  17. ncbi request reprint In vitro reconstitution of monogalactosyldiacylglycerol (MGDG) synthase regulation by thioredoxin
    Yoshiki Yamaryo
    Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 B 14 Nagatsuta cho, Midori ku, Yokohama, Kanagawa 226 8501, Japan
    FEBS Lett 580:4086-90. 2006
    ..Because thioredoxin efficiently reduced disulfide bonds to enhance MGD activity in vitro, MGD is potentially an envelope-bound thioredoxin target protein in higher plants...
  18. ncbi request reprint Significance of the epsilon subunit in the thiol modulation of chloroplast ATP synthase
    Hiroki Konno
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259 R1 8, Midori ku, Yokohama 226 8503, Japan
    Biochem Biophys Res Commun 318:17-24. 2004
    ..In addition, a structural requirement for the redox regulation of ATP hydrolysis activity might be different from that for the ATP synthesis activity...
  19. ncbi request reprint Target proteins of the cytosolic thioredoxins in Arabidopsis thaliana
    Daisuke Yamazaki
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Midori ku, Yokohama, 226 8503 Japan
    Plant Cell Physiol 45:18-27. 2004
    ..The results in this study and recent proteomics studies on the target proteins of chloroplast thioredoxin indicate the versatility and the physiological significance of thioredoxin as reductant in plant cell...
  20. ncbi request reprint ATP synthase--a marvellous rotary engine of the cell
    M Yoshida
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama 226 8503, Japan
    Nat Rev Mol Cell Biol 2:669-77. 2001
    ..The mechanisms by which rotation and catalysis are coupled in the working enzyme are now being unravelled on a molecular scale...
  21. ncbi request reprint Thioredoxin-h1 reduces and reactivates the oxidized cytosolic malate dehydrogenase dimer in higher plants
    Satoshi Hara
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259 R1 8, Midori ku, Yokohama 226 8503, Japan
    J Biol Chem 281:32065-71. 2006
    ..These results demonstrate that the oxidized form cytMDH dimer is a preferable target protein of the reduced form thioredoxin-h1 as suggested by thioredoxin affinity chromatography...
  22. ncbi request reprint HCF164 receives reducing equivalents from stromal thioredoxin across the thylakoid membrane and mediates reduction of target proteins in the thylakoid lumen
    Ken Motohashi
    The ATP System Project, ERATO, JST, Nagatsuta 5800 3, Midori ku, Yokohama, Japan
    J Biol Chem 281:35039-47. 2006
    ..The data presented here suggest that HCF164 serves as an important transducer of reducing equivalents to proteins in the thylakoid lumen...
  23. ncbi request reprint Physiological impact of intrinsic ADP inhibition of cyanobacterial FoF1 conferred by the inherent sequence inserted into the gammasubunit
    Ei Ichiro Sunamura
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259 R1 8, Midori ku, Yokohama 226 8503, Japan
    Plant Cell Physiol 51:855-65. 2010
    ..We believe that the physiological significance of this increased likelihood of shifting into the ADP inhibition state allows the intracellular ATP levels to be maintained, which is especially critical for photosynthetic organisms...
  24. ncbi request reprint Synchronized domain-opening motion of GroEL is essential for communication between the two rings
    K Shiseki
    Chemical Resources Laboratory, Tokyo Institute of Technology, 4259 Nagatsuta, Yokohama, 226-8503, Japan
    J Biol Chem 276:11335-8. 2001
    ..Taken together, cooperative conformational transitions in GroEL rings ensure the functional communication between the two rings of GroEL...
  25. ncbi request reprint Chloroplast cyclophilin is a target protein of thioredoxin. Thiol modulation of the peptidyl-prolyl cis-trans isomerase activity
    Ken Motohashi
    ATP System Project, Exploratory Research for Advanced Technology ERATO, Japan Science and Technology Corporation, and the Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259, Yokohama 226 8503, Japan
    J Biol Chem 278:31848-52. 2003
    ..Because four cysteine residues in Arabidopsis thaliana cyclophilin were conserved in the isoforms from several organisms, it appears that this redox regulation must be one of the common regulation systems of cyclophilin...
  26. pmc The regulator of the F1 motor: inhibition of rotation of cyanobacterial F1-ATPase by the epsilon subunit
    Hiroki Konno
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta, Yokohama, Japan
    EMBO J 25:4596-604. 2006
    ..These results suggest that the epsilon subunit of chloroplast-type ATP synthase plays an important regulator for the rotary motor enzyme, thus preventing wasteful ATP hydrolysis...
  27. ncbi request reprint The significance of type II and PrxQ peroxiredoxins for antioxidative stress response in the purple bacterium Rhodobacter sphaeroides
    Masahiro Wakita
    Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226 8501, Japan
    J Biol Chem 282:27792-801. 2007
    ..The gene disruptants also demonstrated reduced levels of photopigment synthesis, suggesting that the peroxiredoxins are directly or indirectly involved in regulated synthesis of the photosynthetic apparatus...
  28. doi request reprint Identification of thioredoxin targeted proteins using thioredoxin single cysteine mutant-immobilized resin
    Ken Motohashi
    Chemical Resources Laboratory, Tokyo Institute of Technology, Yokohama, Japan
    Methods Mol Biol 479:117-31. 2009
    ..Following the development of this technique, more than one hundred proteins have been reported as potential Trx targets, allowing significant progress to be made in our knowledge and understanding of Trx-target proteins...
  29. ncbi request reprint A facilitated electron transfer of copper--zinc superoxide dismutase (SOD) based on a cysteine-bridged SOD electrode
    Yang Tian
    Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama, Japan
    Biochim Biophys Acta 1569:151-8. 2002
    ..In addition, we found that the SOD confined on the electrode can be expected to possess its inherent enzymatic activity for dismutation of the superoxide ion...
  30. ncbi request reprint Binary reducing equivalent pathways using NADPH-thioredoxin reductase and ferredoxin-thioredoxin reductase in the cyanobacterium Synechocystis sp. strain PCC 6803
    Shoko Hishiya
    Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta 4259 R1 8, Midori ku, Yokohama, 226 8503 Japan
    Plant Cell Physiol 49:11-8. 2008
    ..A study of the binary reducing equivalent pathways in cyanobacterial cells is reported here...
  31. ncbi request reprint Anti-oxidative stress system in cyanobacteria. Significance of type II peroxiredoxin and the role of 1-Cys peroxiredoxin in Synechocystis sp. strain PCC 6803
    Naomi Hosoya-Matsuda
    Chemical Resources Laboratory, Tokyo Institute of Technology, Midori ku, Yokohama 226 8503, Japan
    J Biol Chem 280:840-6. 2005
    ..The results indicate the physiological significance of two different peroxiredoxins as an anti-oxidative stress system in cyanobacteria...
  32. ncbi request reprint Inverse regulation of rotation of F1-ATPase by the mutation at the regulatory region on the gamma subunit of chloroplast ATP synthase
    Hanayo Ueoka-Nakanishi
    ATP System Project, Exploratory Research for Advanced Technology ERATO, Japan Science and Technology Agency JST, 5800 3 Nagatsuta cho, Midori ku, Yokohama 226 0026, Japan
    J Biol Chem 279:16272-7. 2004
    ..These results obtained by the single molecule analysis of the redox regulation provide further insights into the regulation mechanism of the rotary enzyme...
  33. ncbi request reprint Complete inhibition and partial Re-activation of single F1-ATPase molecules by tentoxin: new properties of the re-activated enzyme
    Penka Pavlova
    Department of Structural Biology, Faculty of Earth and Life Science, Vrije Universiteit Amsterdam, The Netherlands
    J Biol Chem 279:9685-8. 2004
    ....
  34. ncbi request reprint A thermostable enzyme as an experimental platform to study properties of less stable homologues
    Holger Lill
    Department of Structural Biology, Faculty of Earth and Life Science, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
    Protein Eng Des Sel 17:553-5. 2004
    ..Using F(1)-ATPase as a case study, we tackled this problem by introducing function-determining domains from a difficult-to-handle variety of an enzyme into a stable homologue...
  35. ncbi request reprint Two cAMP receptor proteins with different biochemical properties in the filamentous cyanobacterium Anabaena sp. PCC 7120
    Takayuki Suzuki
    Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro, Tokyo 153 8902, Japan
    FEBS Lett 571:154-60. 2004
    ..8 microM, among bacterial CRPs. A gel mobility shift assay elucidated that AnCrpA and AnCrpB formed a complex with the consensus DNA sequence in the presence of cAMP, although AnCrpB did not have ordinary DNA-binding motifs...
  36. ncbi request reprint Substitution of a single amino acid switches the tentoxin-resistant thermophilic F1-ATPase into a tentoxin-sensitive enzyme
    Georg Groth
    Department of Plant Biochemistry, Heinrich Heine Universitat, D 40225 Dusseldorf, Germany
    J Biol Chem 277:20117-9. 2002
    ..However, mutation betaSer(66) --> Ala, predicted to provide a crucial hydrogen bond with the inhibitor, resulted in tentoxin inhibition of ATP hydrolysis comparable with the situation found with the chloroplast enzyme...